Wt: 935.0 BDBM228843 | Wt: 993.0 BDBM228841 | Wt: 993.0 BDBM228842 | Wt: 993.0 BDBM228844 | Wt: 1051.1 BDBM228840 |
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [133-300] (Homo sapiens (Human)) | BDBM228840 (PTHRct-8 | QEEWETVM) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | 8.0 | 25 |
The University of Queensland | Assay Description ITC measurements were conducted on a Microcal iTC200 (Malvern Instruments) in buffer consisting of 25 mM Tris (pH 8.0) and 100 mM NaCl. Proteins were... | Biochemistry 56: 2584-2593 (2017) Article DOI: 10.1021/acs.biochem.7b00078 BindingDB Entry DOI: 10.7270/Q2QV3KD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140] (Homo sapiens (Human)) | BDBM228840 (PTHRct-8 | QEEWETVM) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | 8.0 | 25 |
The University of Queensland | Assay Description ITC measurements were conducted on a Microcal iTC200 (Malvern Instruments) in buffer consisting of 25 mM Tris (pH 8.0) and 100 mM NaCl. Proteins were... | Biochemistry 56: 2584-2593 (2017) Article DOI: 10.1021/acs.biochem.7b00078 BindingDB Entry DOI: 10.7270/Q2QV3KD9 | |||||||||||
More data for this Ligand-Target Pair |