Found 114 hits with Last Name = 'donetti' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 4
(RAT) | BDBM50007872
(3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...)Show SMILES CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| Show InChI InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(RAT) | BDBM82247
(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 | PDB
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| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
Reactome pathway KEGG
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| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM81444
(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)Show InChI InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
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| PC cid PC sid UniChem
Patents
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| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(RAT) | BDBM81768
(BENZYLIC ACID | CAS_6581-06-2 | NSC_5311391 | Quin...)Show InChI InChI=1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid PDB UniChem
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| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM35234
(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 | PDB
Reactome pathway KEGG
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| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Rattus norvegicus) | BDBM25764
(ALPRENOLOL,(+) | ALPRENOLOL,(-) | Alfeprol | Alphe...)Show InChI InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 | PDB MMDB
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| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(RAT) | BDBM50241143
((MDL 72222)3,5-Dichloro-benzoic acid 8-methyl-8-az...)Show SMILES CN1C2CCC1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1 |THB:9:7:1:3.4| Show InChI InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3 | PDB
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| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007887
(3-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCCC1CC(C2)NC(=O)n1c2ccccc2n(C)c1=O |THB:10:8:1:3.5.4| Show InChI InChI=1S/C18H24N4O2/c1-20-13-6-5-7-14(20)11-12(10-13)19-17(23)22-16-9-4-3-8-15(16)21(2)18(22)24/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| PubMed
| 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat)) | BDBM25764
(ALPRENOLOL,(+) | ALPRENOLOL,(-) | Alfeprol | Alphe...)Show InChI InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 | PDB
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| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50031942
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)Show SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34 |r,c:24| Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1 | PDB
Reactome pathway KEGG
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| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007868
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES CN1C2CCCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |THB:10:8:1:3.5.4| Show InChI InChI=1S/C17H22N4O2/c1-20-12-5-4-6-13(20)10-11(9-12)18-16(22)21-15-8-3-2-7-14(15)19-17(21)23/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,22)(H,19,23) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007879
(3-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2n(C)c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C17H22N4O2/c1-19-12-7-8-13(19)10-11(9-12)18-16(22)21-15-6-4-3-5-14(15)20(2)17(21)23/h3-6,11-13H,7-10H2,1-2H3,(H,18,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
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| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50108392
((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12 |r,THB:9:7:4.3:1| Show InChI InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+ | PDB
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| PDB PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007884
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES O=C(NC1CN2CCC1CC2)n1c2ccccc2[nH]c1=O |THB:2:3:7.6:9.10,(2.42,-9.19,;3.37,-10.41,;4.89,-10.18,;6.01,-9.14,;6.78,-7.92,;8.5,-7.15,;8.22,-5.37,;7.26,-6.33,;7.67,-8.26,;9.25,-9.22,;10.05,-8.08,;2.77,-11.82,;1.29,-12.32,;-.02,-11.56,;-1.35,-12.33,;-1.35,-13.87,;-.02,-14.64,;1.32,-13.87,;2.8,-14.34,;3.7,-13.07,;5.24,-13.07,)| Show InChI InChI=1S/C15H18N4O2/c20-14-16-11-3-1-2-4-13(11)19(14)15(21)17-12-9-18-7-5-10(12)6-8-18/h1-4,10,12H,5-9H2,(H,16,20)(H,17,21) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Patents
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| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007870
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES CN1C2CCCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O |THB:10:8:1:3.5.4| Show InChI InChI=1S/C17H21N3O3/c1-19-11-5-4-6-12(19)10-13(9-11)23-17(22)20-15-8-3-2-7-14(15)18-16(20)21/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,21) | PDB
UniProtKB/SwissProt
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| PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007872
(3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...)Show SMILES CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| Show InChI InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) | PDB
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| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat)) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB
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| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat)) | BDBM35256
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 | PDB
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| Article PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007886
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C16H20N4O2/c1-19-11-6-7-12(19)9-10(8-11)17-15(21)20-14-5-3-2-4-13(14)18-16(20)22/h2-5,10-12H,6-9H2,1H3,(H,17,21)(H,18,22) | PDB
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(RAT) | BDBM50017696
((2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiaz...)Show InChI InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 | KEGG
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Patents
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| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM21393
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 | PDB
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| 6.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007881
(4-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cccc(C)c2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C17H21N3O3/c1-10-4-3-5-14-15(10)18-16(21)20(14)17(22)23-13-8-11-6-7-12(9-13)19(11)2/h3-5,11-13H,6-9H2,1-2H3,(H,18,21) | PDB
UniProtKB/SwissProt
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| CHEMBL KEGG PC cid PC sid UniChem
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| 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM21393
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 | PDB
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| 8.13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007858
(3-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2n(C)c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C17H21N3O3/c1-18-11-7-8-12(18)10-13(9-11)23-17(22)20-15-6-4-3-5-14(15)19(2)16(20)21/h3-6,11-13H,7-10H2,1-2H3 | PDB
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007882
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES O=C(OC1CN2CCC1CC2)n1c2ccccc2[nH]c1=O |THB:2:3:7.6:9.10,(4.68,-13,;5.62,-14.22,;7.14,-14.01,;8.27,-12.95,;9.04,-11.73,;10.74,-10.96,;10.47,-9.2,;9.51,-10.16,;9.91,-12.09,;11.5,-13.04,;12.3,-11.89,;5.04,-15.64,;3.57,-16.12,;2.24,-15.37,;.91,-16.14,;.91,-17.68,;2.24,-18.45,;3.57,-17.68,;5.06,-18.14,;5.97,-16.89,;7.51,-16.89,)| Show InChI InChI=1S/C15H17N3O3/c19-14-16-11-3-1-2-4-12(11)18(14)15(20)21-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,19) | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(RAT) | BDBM7966
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) | PDB
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| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007888
(3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxy...)Show SMILES CCn1c2ccccc2n(C(=O)OC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| Show InChI InChI=1S/C18H23N3O3/c1-3-20-15-6-4-5-7-16(15)21(17(20)22)18(23)24-14-10-12-8-9-13(11-14)19(12)2/h4-7,12-14H,3,8-11H2,1-2H3 | PDB
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| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(RAT) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB
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| PDB Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM84952
(BIMT 17 | CAS_127941 | NSC_127941)Show SMILES FC(F)(F)c1ccc(cc1)N1CCN(CCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C20H21F3N4O/c21-20(22,23)15-5-7-16(8-6-15)26-12-9-25(10-13-26)11-14-27-18-4-2-1-3-17(18)24-19(27)28/h1-8H,9-14H2,(H,24,28) | PDB
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| 19.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007857
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES O=C(NC1CCN2CCCC1C2)n1c2ccccc2[nH]c1=O |TLB:2:3:11:7.9.8| Show InChI InChI=1S/C16H20N4O2/c21-15(17-12-7-9-19-8-3-4-11(12)10-19)20-14-6-2-1-5-13(14)18-16(20)22/h1-2,5-6,11-12H,3-4,7-10H2,(H,17,21)(H,18,22) | PDB
UniProtKB/SwissProt
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007874
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C16H19N3O3/c1-18-10-6-7-11(18)9-12(8-10)22-16(21)19-14-5-3-2-4-13(14)17-15(19)20/h2-5,10-12H,6-9H2,1H3,(H,17,20) | PDB
UniProtKB/SwissProt
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| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM82561
(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3/t12-,13+,14+ | PDB
UniProtKB/SwissProt
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| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007869
(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(F)cc2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C16H18FN3O3/c1-19-10-3-4-11(19)8-12(7-10)23-16(22)20-14-5-2-9(17)6-13(14)18-15(20)21/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,18,21) | PDB
UniProtKB/SwissProt
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| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007885
(6-Fluoro-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cc(F)ccc2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C16H18FN3O3/c1-19-10-3-4-11(19)8-12(7-10)23-16(22)20-14-6-9(17)2-5-13(14)18-15(20)21/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,18,21) | PDB
UniProtKB/SwissProt
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Similars
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| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007893
(8,8-Dimethyl-3-(2-oxo-2,3-dihydro-benzoimidazole-1...)Show SMILES C[N+]1(C)C2CCC1CC(C2)OC(=O)n1c2ccccc2[nH]c1=O |THB:10:8:1:4.5| Show InChI InChI=1S/C17H21N3O3/c1-20(2)11-7-8-12(20)10-13(9-11)23-17(22)19-15-6-4-3-5-14(15)18-16(19)21/h3-6,11-13H,7-10H2,1-2H3/p+1 | PDB
UniProtKB/SwissProt
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Similars
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| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM84952
(BIMT 17 | CAS_127941 | NSC_127941)Show SMILES FC(F)(F)c1ccc(cc1)N1CCN(CCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C20H21F3N4O/c21-20(22,23)15-5-7-16(8-6-15)26-12-9-25(10-13-26)11-14-27-18-4-2-1-3-17(18)24-19(27)28/h1-8H,9-14H2,(H,24,28) | PDB
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| 47.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | PDB
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| 47.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | PDB
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| 56.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007873
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show InChI InChI=1S/C13H15N3O3/c17-12-15-10-3-1-2-4-11(10)16(12)13(18)19-9-5-7-14-8-6-9/h1-4,9,14H,5-8H2,(H,15,17) | PDB
UniProtKB/SwissProt
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Similars
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| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM84952
(BIMT 17 | CAS_127941 | NSC_127941)Show SMILES FC(F)(F)c1ccc(cc1)N1CCN(CCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C20H21F3N4O/c21-20(22,23)15-5-7-16(8-6-15)26-12-9-25(10-13-26)11-14-27-18-4-2-1-3-17(18)24-19(27)28/h1-8H,9-14H2,(H,24,28) | PDB
Reactome pathway KEGG
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| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007897
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES CN1C2CCCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |TLB:10:8:1:3.5.4| Show InChI InChI=1S/C17H22N4O2/c1-20-12-5-4-6-13(20)10-11(9-12)18-16(22)21-15-8-3-2-7-14(15)19-17(21)23/h2-3,7-8,11-13H,4-6,9-10H2,1H3,(H,18,22)(H,19,23) | PDB
UniProtKB/SwissProt
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| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007860
(7-Methyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2c(C)cccc2[nH]c1=O |THB:9:7:1:3.4| Show InChI InChI=1S/C17H21N3O3/c1-10-4-3-5-14-15(10)20(16(21)18-14)17(22)23-13-8-11-6-7-12(9-13)19(11)2/h3-5,11-13H,6-9H2,1-2H3,(H,18,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| 306 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007866
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show InChI InChI=1S/C14H18N4O2/c1-17-8-6-10(7-9-17)15-13(19)18-12-5-3-2-4-11(12)16-14(18)20/h2-5,10H,6-9H2,1H3,(H,15,19)(H,16,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 436 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 871 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(RAT) | BDBM21393
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 955 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Italia
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 352: 276-82 (1995)
Article DOI: 10.1007/bf00168557 BindingDB Entry DOI: 10.7270/Q2Q52N48 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007859
(2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid...)Show SMILES O=C(OC1CC2CCC(C1)N2Cc1ccccc1)n1c2ccccc2[nH]c1=O |TLB:2:3:10:6.7| Show InChI InChI=1S/C22H23N3O3/c26-21-23-19-8-4-5-9-20(19)25(21)22(27)28-18-12-16-10-11-17(13-18)24(16)14-15-6-2-1-3-7-15/h1-9,16-18H,10-14H2,(H,23,26) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007878
(2-Oxo-5-trifluoromethyl-2,3-dihydro-benzoimidazole...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2ccc(cc2[nH]c1=O)C(F)(F)F |THB:9:7:1:3.4| Show InChI InChI=1S/C17H18F3N3O3/c1-22-10-3-4-11(22)8-12(7-10)26-16(25)23-14-5-2-9(17(18,19)20)6-13(14)21-15(23)24/h2,5-6,10-12H,3-4,7-8H2,1H3,(H,21,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50007890
(6-Acetyl-2-oxo-2,3-dihydro-benzoimidazole-1-carbox...)Show SMILES CN1C2CCC1CC(C2)OC(=O)n1c2cc(ccc2[nH]c1=O)C(C)=O |THB:9:7:1:3.4| Show InChI InChI=1S/C18H21N3O4/c1-10(22)11-3-6-15-16(7-11)21(17(23)19-15)18(24)25-14-8-12-4-5-13(9-14)20(12)2/h3,6-7,12-14H,4-5,8-9H2,1-2H3,(H,19,23) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto De Angeli
Curated by ChEMBL
| Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex |
J Med Chem 33: 2101-8 (1990)
BindingDB Entry DOI: 10.7270/Q22Z164J |
More data for this Ligand-Target Pair | |