Found 200 hits with Last Name = 'gondela' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610836
![PNG](/data/jpeg/tenK5061/BindingDB_50610836.png) (MSC-4381)Show SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccc(Cl)cc1C#Cc1cnc(cc1OC)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610833
![PNG](/data/jpeg/tenK5061/BindingDB_50610833.png) (CHEMBL5276884)Show SMILES COc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1cnc(C(O)=O)c(C)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610834
![PNG](/data/jpeg/tenK5061/BindingDB_50610834.png) (CHEMBL5279064)Show SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610830
![PNG](/data/jpeg/tenK5061/BindingDB_50610830.png) (CHEMBL5267752)Show SMILES Cc1ccc2cccnc2c1S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610837
![PNG](/data/jpeg/tenK5061/BindingDB_50610837.png) (CHEMBL5281492)Show SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1cnc(C(O)=O)c(NC)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610835
![PNG](/data/jpeg/tenK5061/BindingDB_50610835.png) (CHEMBL5267349)Show SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1cnc(cc1OC)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610826
![PNG](/data/jpeg/tenK5061/BindingDB_50610826.png) (CHEMBL5287351)Show SMILES Cc1cnc2c(cccc2c1)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610827
![PNG](/data/jpeg/tenK5061/BindingDB_50610827.png) (CHEMBL5287780)Show SMILES Cc1ccnc2c(cccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610824
![PNG](/data/jpeg/tenK5061/BindingDB_50610824.png) (CHEMBL5268966)Show SMILES OC(=O)c1ccc(cn1)C#Cc1ccccc1NS(=O)(=O)c1cccc2cccnc12 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610829
![PNG](/data/jpeg/tenK5061/BindingDB_50610829.png) (CHEMBL5288904)Show SMILES Cc1cc(c2ncccc2c1)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610831
![PNG](/data/jpeg/tenK5061/BindingDB_50610831.png) (CHEMBL5265956)Show SMILES Cc1ccc2cccnc2c1S(=O)(=O)Nc1ccccc1C#Cc1cnc(C(O)=O)c(C)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610825
![PNG](/data/jpeg/tenK5061/BindingDB_50610825.png) (CHEMBL5266104)Show SMILES Cc1ccc2cccc(c2n1)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610828
![PNG](/data/jpeg/tenK5061/BindingDB_50610828.png) (CHEMBL5271816)Show SMILES Cc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 222 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Mus musculus) | BDBM50610868
![PNG](/data/jpeg/tenK5061/BindingDB_50610868.png) (CHEMBL5282978)Show SMILES CC1(C)\C(=C\C=C\C=C\C2=[N+](CCCS([O-])(=O)=O)c3ccc(cc3C2(C)CCCCCC(=O)NCCOCCOCCOCCOc2ccnc3c(cccc23)S(=O)(=O)Nc2ccccc2C#Cc2ccc(nc2)C(O)=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O |c:9| | MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 301 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508562
![PNG](/data/jpeg/tenK5050/BindingDB_50508562.png) (CHEMBL4541928)Show SMILES CN1CCCC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C29H29N7O/c1-35-12-3-4-21(18-35)34-29(37)23-7-9-30-17-26(23)33-22-15-24(28-25(16-22)31-10-11-32-28)20-6-5-19-8-13-36(2)27(19)14-20/h5-11,13-17,21,33H,3-4,12,18H2,1-2H3,(H,34,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM21998
![PNG](/data/jpeg/tenK2/BindingDB_21998.png) (6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)Show SMILES CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C21H27N5O5S/c1-10(2)7-25-20-17(18(28)24(5)21(25)30)16(19(29)26-8-13(27)9-31-26)15(32-20)6-14-11(3)22-23-12(14)4/h10,13,27H,6-9H2,1-5H3,(H,22,23)/t13-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508559
![PNG](/data/jpeg/tenK5050/BindingDB_50508559.png) (CHEMBL4592338)Show SMILES CN1CC[C@H](C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3scc(C)c3c2)c2nccnc2c1 |r| Show InChI InChI=1S/C28H26N6OS/c1-17-16-36-26-4-3-18(11-22(17)26)23-12-20(13-24-27(23)31-9-8-30-24)32-25-14-29-7-5-21(25)28(35)33-19-6-10-34(2)15-19/h3-5,7-9,11-14,16,19,32H,6,10,15H2,1-2H3,(H,33,35)/t19-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM21998
![PNG](/data/jpeg/tenK2/BindingDB_21998.png) (6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)Show SMILES CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C21H27N5O5S/c1-10(2)7-25-20-17(18(28)24(5)21(25)30)16(19(29)26-8-13(27)9-31-26)15(32-20)6-14-11(3)22-23-12(14)4/h10,13,27H,6-9H2,1-5H3,(H,22,23)/t13-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50103571
![PNG](/data/jpeg/tenK5010/BindingDB_50103571.png) (CHEMBL3335793)Show SMILES CC(C)n1c2sc(Cc3c(C)[nH]nc3C(F)(F)F)c(C(=O)N3C[C@](C)(O)CO3)c2c(=O)n(C)c1=O |r| | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508565
![PNG](/data/jpeg/tenK5050/BindingDB_50508565.png) (CHEMBL4439789)Show SMILES CN1CC[C@@H](C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3scc(C)c3c2)c2nccnc2c1 |r| Show InChI InChI=1S/C28H26N6OS/c1-17-16-36-26-4-3-18(11-22(17)26)23-12-20(13-24-27(23)31-9-8-30-24)32-25-14-29-7-5-21(25)28(35)33-19-6-10-34(2)15-19/h3-5,7-9,11-14,16,19,32H,6,10,15H2,1-2H3,(H,33,35)/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508535
![PNG](/data/jpeg/tenK5050/BindingDB_50508535.png) (CHEMBL4465124)Show SMILES CC(=O)N1CCCC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C30H29N7O2/c1-19(38)37-12-3-4-22(18-37)35-30(39)24-7-9-31-17-27(24)34-23-15-25(29-26(16-23)32-10-11-33-29)21-6-5-20-8-13-36(2)28(20)14-21/h5-11,13-17,22,34H,3-4,12,18H2,1-2H3,(H,35,39) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508542
![PNG](/data/jpeg/tenK5050/BindingDB_50508542.png) (CHEMBL4449586)Show SMILES CN1CCC(CNS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 Show InChI InChI=1S/C29H30N6O2S/c1-34-13-9-20(19-34)18-32-38(36,37)28-6-4-3-5-25(28)33-23-16-24(29-26(17-23)30-11-12-31-29)22-8-7-21-10-14-35(2)27(21)15-22/h3-8,10-12,14-17,20,32-33H,9,13,18-19H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610832
![PNG](/data/jpeg/tenK5061/BindingDB_50610832.png) (CHEMBL5282741)Show SMILES COc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508560
![PNG](/data/jpeg/tenK5050/BindingDB_50508560.png) (CHEMBL4471955)Show SMILES CN1CCC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C28H27N7O/c1-34-11-7-20(17-34)33-28(36)22-5-8-29-16-25(22)32-21-14-23(27-24(15-21)30-9-10-31-27)19-4-3-18-6-12-35(2)26(18)13-19/h3-6,8-10,12-16,20,32H,7,11,17H2,1-2H3,(H,33,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508526
![PNG](/data/jpeg/tenK5050/BindingDB_50508526.png) (CHEMBL4542245)Show SMILES CN1CCC(C1)NC(=O)c1ccncc1Nc1cc(-c2cc(F)c3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C28H26FN7O/c1-35-9-4-18(16-35)34-28(37)21-3-6-30-15-25(21)33-19-13-22(27-24(14-19)31-7-8-32-27)17-11-23(29)20-5-10-36(2)26(20)12-17/h3,5-8,10-15,18,33H,4,9,16H2,1-2H3,(H,34,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508537
![PNG](/data/jpeg/tenK5050/BindingDB_50508537.png) (CHEMBL4461874)Show SMILES CC(=O)N1CCC(CC1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C30H29N7O2/c1-19(38)37-13-7-22(8-14-37)35-30(39)24-5-9-31-18-27(24)34-23-16-25(29-26(17-23)32-10-11-33-29)21-4-3-20-6-12-36(2)28(20)15-21/h3-6,9-12,15-18,22,34H,7-8,13-14H2,1-2H3,(H,35,39) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610830
![PNG](/data/jpeg/tenK5061/BindingDB_50610830.png) (CHEMBL5267752)Show SMILES Cc1ccc2cccnc2c1S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610852
![PNG](/data/jpeg/tenK5061/BindingDB_50610852.png) (CHEMBL5287835)Show SMILES COc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(cc1)C(O)=O | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508540
![PNG](/data/jpeg/tenK5050/BindingDB_50508540.png) (CHEMBL4470835)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2cnccc2C(=O)Nc2cncnc2)cc2nccnc12 Show InChI InChI=1S/C27H20N8O/c1-35-9-5-17-2-3-18(10-25(17)35)22-11-19(12-23-26(22)32-8-7-31-23)33-24-15-28-6-4-21(24)27(36)34-20-13-29-16-30-14-20/h2-16,33H,1H3,(H,34,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508564
![PNG](/data/jpeg/tenK5050/BindingDB_50508564.png) (CHEMBL4553861)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2ccccc2S(=O)(=O)NCc2cncnc2)cc2nccnc12 Show InChI InChI=1S/C28H23N7O2S/c1-35-11-8-20-6-7-21(12-26(20)35)23-13-22(14-25-28(23)32-10-9-31-25)34-24-4-2-3-5-27(24)38(36,37)33-17-19-15-29-18-30-16-19/h2-16,18,33-34H,17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50103571
![PNG](/data/jpeg/tenK5010/BindingDB_50103571.png) (CHEMBL3335793)Show SMILES CC(C)n1c2sc(Cc3c(C)[nH]nc3C(F)(F)F)c(C(=O)N3C[C@](C)(O)CO3)c2c(=O)n(C)c1=O |r| | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508543
![PNG](/data/jpeg/tenK5050/BindingDB_50508543.png) (CHEMBL4518022)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2ccccc2S(=O)(=O)NCC2CCOCC2)cc2nccnc12 Show InChI InChI=1S/C29H29N5O3S/c1-34-13-8-21-6-7-22(16-27(21)34)24-17-23(18-26-29(24)31-12-11-30-26)33-25-4-2-3-5-28(25)38(35,36)32-19-20-9-14-37-15-10-20/h2-8,11-13,16-18,20,32-33H,9-10,14-15,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508527
![PNG](/data/jpeg/tenK5050/BindingDB_50508527.png) (CHEMBL4437856)Show SMILES CN1CC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C27H25N7O/c1-33-15-20(16-33)32-27(35)21-5-7-28-14-24(21)31-19-12-22(26-23(13-19)29-8-9-30-26)18-4-3-17-6-10-34(2)25(17)11-18/h3-14,20,31H,15-16H2,1-2H3,(H,32,35) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508554
![PNG](/data/jpeg/tenK5050/BindingDB_50508554.png) (CHEMBL4459213)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2cnccc2C(=O)NCC2COCCN2)cc2nccnc12 Show InChI InChI=1S/C28H27N7O2/c1-35-10-5-18-2-3-19(12-26(18)35)23-13-20(14-24-27(23)32-8-7-31-24)34-25-16-29-6-4-22(25)28(36)33-15-21-17-37-11-9-30-21/h2-8,10,12-14,16,21,30,34H,9,11,15,17H2,1H3,(H,33,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508544
![PNG](/data/jpeg/tenK5050/BindingDB_50508544.png) (CHEMBL4538989)Show SMILES CN1CCC(C1)NS(=O)(=O)c1ccccc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C28H28N6O2S/c1-33-13-10-21(18-33)32-37(35,36)27-6-4-3-5-24(27)31-22-16-23(28-25(17-22)29-11-12-30-28)20-8-7-19-9-14-34(2)26(19)15-20/h3-9,11-12,14-17,21,31-32H,10,13,18H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508556
![PNG](/data/jpeg/tenK5050/BindingDB_50508556.png) (CHEMBL4465233)Show SMILES Cn1cc(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)cn1 Show InChI InChI=1S/C27H22N8O/c1-34-10-6-17-3-4-18(11-25(17)34)22-12-19(13-23-26(22)30-9-8-29-23)32-24-15-28-7-5-21(24)27(36)33-20-14-31-35(2)16-20/h3-16,32H,1-2H3,(H,33,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508558
![PNG](/data/jpeg/tenK5050/BindingDB_50508558.png) (CHEMBL4438803)Show SMILES CN1CCC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3sc(N)nc3c2)c2nccnc2c1 Show InChI InChI=1S/C26H24N8OS/c1-34-9-5-16(14-34)32-25(35)18-4-6-28-13-22(18)31-17-11-19(24-21(12-17)29-7-8-30-24)15-2-3-23-20(10-15)33-26(27)36-23/h2-4,6-8,10-13,16,31H,5,9,14H2,1H3,(H2,27,33)(H,32,35) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508563
![PNG](/data/jpeg/tenK5050/BindingDB_50508563.png) (CHEMBL4576710)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2ccccc2S(=O)(=O)N2CCOCC2)cc2nccnc12 Show InChI InChI=1S/C27H25N5O3S/c1-31-11-8-19-6-7-20(16-25(19)31)22-17-21(18-24-27(22)29-10-9-28-24)30-23-4-2-3-5-26(23)36(33,34)32-12-14-35-15-13-32/h2-11,16-18,30H,12-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508538
![PNG](/data/jpeg/tenK5050/BindingDB_50508538.png) (CHEMBL4472403)Show SMILES CN1CCC(CC1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C29H29N7O/c1-35-12-7-21(8-13-35)34-29(37)23-5-9-30-18-26(23)33-22-16-24(28-25(17-22)31-10-11-32-28)20-4-3-19-6-14-36(2)27(19)15-20/h3-6,9-11,14-18,21,33H,7-8,12-13H2,1-2H3,(H,34,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508557
![PNG](/data/jpeg/tenK5050/BindingDB_50508557.png) (CHEMBL4539068)Show SMILES Cn1cc(CNS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)cn1 Show InChI InChI=1S/C28H25N7O2S/c1-34-12-9-20-7-8-21(13-26(20)34)23-14-22(15-25-28(23)30-11-10-29-25)33-24-5-3-4-6-27(24)38(36,37)32-17-19-16-31-35(2)18-19/h3-16,18,32-33H,17H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610863
![PNG](/data/jpeg/tenK5061/BindingDB_50610863.png) (CHEMBL5280923)Show SMILES OC(=O)c1ccc(cn1)C#Cc1ccccc1NS(=O)(=O)c1cccc2c(OCCOCCOc3ccccc3)ccnc12 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508536
![PNG](/data/jpeg/tenK5050/BindingDB_50508536.png) (CHEMBL4442954)Show SMILES CN1CCC(CC1=O)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C29H27N7O2/c1-35-11-6-18-3-4-19(13-26(18)35)23-14-21(15-24-28(23)32-10-9-31-24)33-25-17-30-8-5-22(25)29(38)34-20-7-12-36(2)27(37)16-20/h3-6,8-11,13-15,17,20,33H,7,12,16H2,1-2H3,(H,34,38) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508530
![PNG](/data/jpeg/tenK5050/BindingDB_50508530.png) (CHEMBL4458729)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2cnccc2C(N)=O)cc2nccnc12 Show InChI InChI=1S/C23H18N6O/c1-29-9-5-14-2-3-15(10-21(14)29)18-11-16(12-19-22(18)27-8-7-26-19)28-20-13-25-6-4-17(20)23(24)30/h2-13,28H,1H3,(H2,24,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610851
![PNG](/data/jpeg/tenK5061/BindingDB_50610851.png) (CHEMBL5290111)Show SMILES CNc1cc(ccc1C(O)=O)C#Cc1ccccc1NS(=O)(=O)c1c(C)ccc2cccnc12 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508545
![PNG](/data/jpeg/tenK5050/BindingDB_50508545.png) (CHEMBL4591819)Show SMILES CN1CCCC(C1)NS(=O)(=O)c1ccccc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C29H30N6O2S/c1-34-14-5-6-22(19-34)33-38(36,37)28-8-4-3-7-25(28)32-23-17-24(29-26(18-23)30-12-13-31-29)21-10-9-20-11-15-35(2)27(20)16-21/h3-4,7-13,15-18,22,32-33H,5-6,14,19H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50610837
![PNG](/data/jpeg/tenK5061/BindingDB_50610837.png) (CHEMBL5281492)Show SMILES CCOc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1cnc(C(O)=O)c(NC)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508529
![PNG](/data/jpeg/tenK5050/BindingDB_50508529.png) (CHEMBL4452425)Show SMILES CN(Cc1cncnc1)S(=O)(=O)c1ccccc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C29H25N7O2S/c1-35-12-9-21-7-8-22(13-27(21)35)24-14-23(15-26-29(24)33-11-10-32-26)34-25-5-3-4-6-28(25)39(37,38)36(2)18-20-16-30-19-31-17-20/h3-17,19,34H,18H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508555
![PNG](/data/jpeg/tenK5050/BindingDB_50508555.png) (CHEMBL4578329)Show SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2cnccc2C(=O)NC2CCNC(=O)C2)cc2nccnc12 Show InChI InChI=1S/C28H25N7O2/c1-35-11-6-17-2-3-18(12-25(17)35)22-13-20(14-23-27(22)32-10-9-30-23)33-24-16-29-7-5-21(24)28(37)34-19-4-8-31-26(36)15-19/h2-3,5-7,9-14,16,19,33H,4,8,15H2,1H3,(H,31,36)(H,34,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508561
![PNG](/data/jpeg/tenK5050/BindingDB_50508561.png) (CHEMBL4448768)Show SMILES CC(=O)N1CC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 Show InChI InChI=1S/C28H25N7O2/c1-17(36)35-15-21(16-35)33-28(37)22-5-7-29-14-25(22)32-20-12-23(27-24(13-20)30-8-9-31-27)19-4-3-18-6-10-34(2)26(18)11-19/h3-14,21,32H,15-16H2,1-2H3,(H,33,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Homo sapiens (Human)) | BDBM50508551
![PNG](/data/jpeg/tenK5050/BindingDB_50508551.png) (CHEMBL4439232)Show SMILES CN1CCC(CNC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 Show InChI InChI=1S/C29H29N7O/c1-35-11-6-19(18-35)16-33-29(37)23-5-8-30-17-26(23)34-22-14-24(28-25(15-22)31-9-10-32-28)21-4-3-20-7-12-36(2)27(20)13-21/h3-5,7-10,12-15,17,19,34H,6,11,16,18H2,1-2H3,(H,33,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Selvita S.A.
Curated by ChEMBL
| Assay Description Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G... |
Bioorg Med Chem Lett 29: 646-653 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.034 BindingDB Entry DOI: 10.7270/Q2BP0620 |
More data for this Ligand-Target Pair | |