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Compile Data Set for Download or QSAR

Found 44 hits with Last Name = 'vermote' and Initial = 'a'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259987
PNG
(CHEMBL4082179)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1F |r|
Show InChI InChI=1S/C20H20ClFN2O5/c21-14-7-3-1-5-12(14)18(26)23-9-16-17(25)20(28,11-29-16)10-24-19(27)13-6-2-4-8-15(13)22/h1-8,16-17,25,28H,9-11H2,(H,23,26)(H,24,27)/t16-,17-,20+/m1/s1
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n/an/an/an/a 4.86E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260002
PNG
(CHEMBL4096484)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNCc1ccccc1 |r|
Show InChI InChI=1S/C20H23ClN2O4/c21-16-9-5-4-8-15(16)19(25)23-11-17-18(24)20(26,13-27-17)12-22-10-14-6-2-1-3-7-14/h1-9,17-18,22,24,26H,10-13H2,(H,23,25)/t17-,18-,20+/m1/s1
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n/an/an/an/a 6.32E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259989
PNG
(CHEMBL4087861)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccncc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-14-8-21-7-6-13(14)18(26)22-9-15-16(24)19(27,11-28-15)10-23-17(25)12-4-2-1-3-5-12/h1-8,15-16,24,27H,9-11H2,(H,22,26)(H,23,25)/t15-,16-,19+/m1/s1
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n/an/an/an/a>2.50E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259991
PNG
(CHEMBL4082997)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccnnc2)OC[C@@]1(O)CNC(=O)c1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C24H24N4O5/c29-21-20(13-25-23(31)19-10-11-27-28-12-19)33-15-24(21,32)14-26-22(30)18-8-6-17(7-9-18)16-4-2-1-3-5-16/h1-12,20-21,29,32H,13-15H2,(H,25,31)(H,26,30)/t20-,21-,24+/m1/s1
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n/an/an/an/a 8.54E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259992
PNG
(Hamamelitannin)
Show SMILES OC1O[C@H](COC(=O)c2cc(O)c(O)c(O)c2)[C@@H](O)[C@]1(O)COC(=O)c1cc(O)c(O)c(O)c1 |r|
Show InChI InChI=1S/C20H20O14/c21-9-1-7(2-10(22)14(9)25)17(28)32-5-13-16(27)20(31,19(30)34-13)6-33-18(29)8-3-11(23)15(26)12(24)4-8/h1-4,13,16,19,21-27,30-31H,5-6H2/t13-,16-,19?,20-/m1/s1
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n/an/an/an/a 1.65E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259993
PNG
(CHEMBL4097749)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)C1CCCCC1 |r|
Show InChI InChI=1S/C20H27ClN2O5/c21-15-9-5-4-8-14(15)19(26)22-10-16-17(24)20(27,12-28-16)11-23-18(25)13-6-2-1-3-7-13/h4-5,8-9,13,16-17,24,27H,1-3,6-7,10-12H2,(H,22,26)(H,23,25)/t16-,17-,20+/m1/s1
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n/an/an/an/a 3.40E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259994
PNG
(CHEMBL4060563)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN1Cc2ccccc2C1=O |r|
Show InChI InChI=1S/C21H21ClN2O5/c22-16-8-4-3-7-15(16)19(26)23-9-17-18(25)21(28,12-29-17)11-24-10-13-5-1-2-6-14(13)20(24)27/h1-8,17-18,25,28H,9-12H2,(H,23,26)/t17-,18-,21+/m1/s1
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n/an/an/an/a 2.09E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259997
PNG
(CHEMBL4075326)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccc(cc2)-c2ccccc2)OC[C@@]1(O)CN1C(=O)c2ccccc2C1=O |r|
Show InChI InChI=1S/C27H24N2O6/c30-23-22(14-28-24(31)19-12-10-18(11-13-19)17-6-2-1-3-7-17)35-16-27(23,34)15-29-25(32)20-8-4-5-9-21(20)26(29)33/h1-13,22-23,30,34H,14-16H2,(H,28,31)/t22-,23-,27+/m1/s1
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n/an/an/an/a 1.21E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259998
PNG
(CHEMBL4077423)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C20H21ClN2O5/c21-15-9-5-4-8-14(15)19(26)22-10-16-17(24)20(27,12-28-16)11-23-18(25)13-6-2-1-3-7-13/h1-9,16-17,24,27H,10-12H2,(H,22,26)(H,23,25)/t16-,17-,20+/m1/s1
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n/an/an/an/a 390n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259995
PNG
(CHEMBL4066540)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2cccnc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-16-13(7-4-8-21-16)18(26)22-9-14-15(24)19(27,11-28-14)10-23-17(25)12-5-2-1-3-6-12/h1-8,14-15,24,27H,9-11H2,(H,22,26)(H,23,25)/t14-,15-,19+/m1/s1
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n/an/an/an/a>2.50E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260004
PNG
(CHEMBL4079978)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2cnccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-14-6-7-21-8-13(14)18(26)22-9-15-16(24)19(27,11-28-15)10-23-17(25)12-4-2-1-3-5-12/h1-8,15-16,24,27H,9-11H2,(H,22,26)(H,23,25)/t15-,16-,19+/m1/s1
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n/an/an/an/a 2.00E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259996
PNG
(CHEMBL4085383)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2)OC[C@@]1(O)CNC(=O)c1ccccc1Cl |r|
Show InChI InChI=1S/C20H21ClN2O5/c21-15-9-5-4-8-14(15)19(26)23-11-20(27)12-28-16(17(20)24)10-22-18(25)13-6-2-1-3-7-13/h1-9,16-17,24,27H,10-12H2,(H,22,25)(H,23,26)/t16-,17-,20+/m1/s1
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n/an/an/an/a 5.58E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260006
PNG
(CHEMBL4078565)
Show SMILES O[C@@H]1[C@@H](CN2C(=O)c3ccccc3C2=O)OC[C@@]1(O)CNC(=O)c1ccccc1Cl |r|
Show InChI InChI=1S/C21H19ClN2O6/c22-15-8-4-3-7-14(15)18(26)23-10-21(29)11-30-16(17(21)25)9-24-19(27)12-5-1-2-6-13(12)20(24)28/h1-8,16-17,25,29H,9-11H2,(H,23,26)/t16-,17-,21+/m1/s1
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n/an/an/an/a 260n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260007
PNG
(CHEMBL4102095)
Show SMILES O[C@@H]1[C@@H](CN2C(=O)c3ccccc3C2=O)OC[C@@]1(O)CNC(=O)c1ccnnc1 |r|
Show InChI InChI=1S/C19H18N4O6/c24-15-14(8-23-17(26)12-3-1-2-4-13(12)18(23)27)29-10-19(15,28)9-20-16(25)11-5-6-21-22-7-11/h1-7,14-15,24,28H,8-10H2,(H,20,25)/t14-,15-,19+/m1/s1
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n/an/an/an/a 5.85E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259999
PNG
(CHEMBL4072992)
Show SMILES Cc1ccc(cc1)C(=O)NC[C@]1(O)CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C21H23ClN2O5/c1-13-6-8-14(9-7-13)19(26)24-11-21(28)12-29-17(18(21)25)10-23-20(27)15-4-2-3-5-16(15)22/h2-9,17-18,25,28H,10-12H2,1H3,(H,23,27)(H,24,26)/t17-,18-,21+/m1/s1
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n/an/an/an/a 4.19E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260001
PNG
(CHEMBL4076813)
Show SMILES CC(=O)NC[C@]1(O)CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C15H19ClN2O5/c1-9(19)18-7-15(22)8-23-12(13(15)20)6-17-14(21)10-4-2-3-5-11(10)16/h2-5,12-13,20,22H,6-8H2,1H3,(H,17,21)(H,18,19)/t12-,13-,15+/m1/s1
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n/an/an/an/a 3.55E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260002
PNG
(CHEMBL4096484)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNCc1ccccc1 |r|
Show InChI InChI=1S/C20H23ClN2O4/c21-16-9-5-4-8-15(16)19(25)23-11-17-18(24)20(26,13-27-17)12-22-10-14-6-2-1-3-7-14/h1-9,17-18,22,24,26H,10-13H2,(H,23,25)/t17-,18-,20+/m1/s1
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n/an/an/an/a 8.42E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260003
PNG
(CHEMBL4088791)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN=[N+]=[N-] |r|
Show InChI InChI=1S/C13H15ClN4O4/c14-9-4-2-1-3-8(9)12(20)16-5-10-11(19)13(21,7-22-10)6-17-18-15/h1-4,10-11,19,21H,5-7H2,(H,16,20)/t10-,11-,13+/m1/s1
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n/an/an/an/a 2.34E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260000
PNG
(CHEMBL4092720)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccoc1 |r|
Show InChI InChI=1S/C18H19ClN2O6/c19-13-4-2-1-3-12(13)17(24)20-7-14-15(22)18(25,10-27-14)9-21-16(23)11-5-6-26-8-11/h1-6,8,14-15,22,25H,7,9-10H2,(H,20,24)(H,21,23)/t14-,15-,18+/m1/s1
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n/an/an/an/a 7.67E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260005
PNG
(CHEMBL4104220)
Show SMILES Cn1nccc1C(=O)NC[C@H]1OC[C@@](O)(CNC(=O)c2ccccc2)[C@@H]1O |r|
Show InChI InChI=1S/C18H22N4O5/c1-22-13(7-8-21-22)17(25)19-9-14-15(23)18(26,11-27-14)10-20-16(24)12-5-3-2-4-6-12/h2-8,14-15,23,26H,9-11H2,1H3,(H,19,25)(H,20,24)/t14-,15-,18+/m1/s1
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n/an/an/an/a 2.35E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259990
PNG
(CHEMBL4103314)
Show SMILES Cn1cncc1C(=O)NC[C@H]1OC[C@@](O)(CNC(=O)c2ccccc2)[C@@H]1O |r|
Show InChI InChI=1S/C18H22N4O5/c1-22-11-19-7-13(22)17(25)20-8-14-15(23)18(26,10-27-14)9-21-16(24)12-5-3-2-4-6-12/h2-7,11,14-15,23,26H,8-10H2,1H3,(H,20,25)(H,21,24)/t14-,15-,18+/m1/s1
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n/an/an/an/a 5.82E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260008
PNG
(CHEMBL4077031)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN1C(=O)c2ccccc2C1=O |r|
Show InChI InChI=1S/C21H19ClN2O6/c22-15-8-4-3-7-14(15)18(26)23-9-16-17(25)21(29,11-30-16)10-24-19(27)12-5-1-2-6-13(12)20(24)28/h1-8,16-17,25,29H,9-11H2,(H,23,26)/t16-,17-,21+/m1/s1
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n/an/an/an/a 3.90E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260000
PNG
(CHEMBL4092720)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccoc1 |r|
Show InChI InChI=1S/C18H19ClN2O6/c19-13-4-2-1-3-12(13)17(24)20-7-14-15(22)18(25,10-27-14)9-21-16(23)11-5-6-26-8-11/h1-6,8,14-15,22,25H,7,9-10H2,(H,20,24)(H,21,23)/t14-,15-,18+/m1/s1
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n/an/an/an/a 6.85E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259997
PNG
(CHEMBL4075326)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccc(cc2)-c2ccccc2)OC[C@@]1(O)CN1C(=O)c2ccccc2C1=O |r|
Show InChI InChI=1S/C27H24N2O6/c30-23-22(14-28-24(31)19-12-10-18(11-13-19)17-6-2-1-3-7-17)35-16-27(23,34)15-29-25(32)20-8-4-5-9-21(20)26(29)33/h1-13,22-23,30,34H,14-16H2,(H,28,31)/t22-,23-,27+/m1/s1
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n/an/an/an/a 2.47E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260008
PNG
(CHEMBL4077031)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN1C(=O)c2ccccc2C1=O |r|
Show InChI InChI=1S/C21H19ClN2O6/c22-15-8-4-3-7-14(15)18(26)23-9-16-17(25)21(29,11-30-16)10-24-19(27)12-5-1-2-6-13(12)20(24)28/h1-8,16-17,25,29H,9-11H2,(H,23,26)/t16-,17-,21+/m1/s1
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n/an/an/an/a 2.63E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259989
PNG
(CHEMBL4087861)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccncc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-14-8-21-7-6-13(14)18(26)22-9-15-16(24)19(27,11-28-15)10-23-17(25)12-4-2-1-3-5-12/h1-8,15-16,24,27H,9-11H2,(H,22,26)(H,23,25)/t15-,16-,19+/m1/s1
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n/an/an/an/a 2.32E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260001
PNG
(CHEMBL4076813)
Show SMILES CC(=O)NC[C@]1(O)CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C15H19ClN2O5/c1-9(19)18-7-15(22)8-23-12(13(15)20)6-17-14(21)10-4-2-3-5-11(10)16/h2-5,12-13,20,22H,6-8H2,1H3,(H,17,21)(H,18,19)/t12-,13-,15+/m1/s1
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n/an/an/an/a 1.54E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259999
PNG
(CHEMBL4072992)
Show SMILES Cc1ccc(cc1)C(=O)NC[C@]1(O)CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C21H23ClN2O5/c1-13-6-8-14(9-7-13)19(26)24-11-21(28)12-29-17(18(21)25)10-23-20(27)15-4-2-3-5-16(15)22/h2-9,17-18,25,28H,10-12H2,1H3,(H,23,27)(H,24,26)/t17-,18-,21+/m1/s1
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n/an/an/an/a 7.97E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259992
PNG
(Hamamelitannin)
Show SMILES OC1O[C@H](COC(=O)c2cc(O)c(O)c(O)c2)[C@@H](O)[C@]1(O)COC(=O)c1cc(O)c(O)c(O)c1 |r|
Show InChI InChI=1S/C20H20O14/c21-9-1-7(2-10(22)14(9)25)17(28)32-5-13-16(27)20(31,19(30)34-13)6-33-18(29)8-3-11(23)15(26)12(24)4-8/h1-4,13,16,19,21-27,30-31H,5-6H2/t13-,16-,19?,20-/m1/s1
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n/an/an/an/a 1.46E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260005
PNG
(CHEMBL4104220)
Show SMILES Cn1nccc1C(=O)NC[C@H]1OC[C@@](O)(CNC(=O)c2ccccc2)[C@@H]1O |r|
Show InChI InChI=1S/C18H22N4O5/c1-22-13(7-8-21-22)17(25)19-9-14-15(23)18(26,11-27-14)10-20-16(24)12-5-3-2-4-6-12/h2-8,14-15,23,26H,9-11H2,1H3,(H,19,25)(H,20,24)/t14-,15-,18+/m1/s1
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n/an/an/an/a 2.93E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260007
PNG
(CHEMBL4102095)
Show SMILES O[C@@H]1[C@@H](CN2C(=O)c3ccccc3C2=O)OC[C@@]1(O)CNC(=O)c1ccnnc1 |r|
Show InChI InChI=1S/C19H18N4O6/c24-15-14(8-23-17(26)12-3-1-2-4-13(12)18(23)27)29-10-19(15,28)9-20-16(25)11-5-6-21-22-7-11/h1-7,14-15,24,28H,8-10H2,(H,20,25)/t14-,15-,19+/m1/s1
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n/an/an/an/a 1.14E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259991
PNG
(CHEMBL4082997)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccnnc2)OC[C@@]1(O)CNC(=O)c1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C24H24N4O5/c29-21-20(13-25-23(31)19-10-11-27-28-12-19)33-15-24(21,32)14-26-22(30)18-8-6-17(7-9-18)16-4-2-1-3-5-16/h1-12,20-21,29,32H,13-15H2,(H,25,31)(H,26,30)/t20-,21-,24+/m1/s1
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n/an/an/an/a 4.54E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259995
PNG
(CHEMBL4066540)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2cccnc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-16-13(7-4-8-21-16)18(26)22-9-14-15(24)19(27,11-28-14)10-23-17(25)12-5-2-1-3-6-12/h1-8,14-15,24,27H,9-11H2,(H,22,26)(H,23,25)/t14-,15-,19+/m1/s1
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n/an/an/an/a>2.50E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259990
PNG
(CHEMBL4103314)
Show SMILES Cn1cncc1C(=O)NC[C@H]1OC[C@@](O)(CNC(=O)c2ccccc2)[C@@H]1O |r|
Show InChI InChI=1S/C18H22N4O5/c1-22-11-19-7-13(22)17(25)20-8-14-15(23)18(26,10-27-14)9-21-16(24)12-5-3-2-4-6-12/h2-7,11,14-15,23,26H,8-10H2,1H3,(H,20,25)(H,21,24)/t14-,15-,18+/m1/s1
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n/an/an/an/a 4.67E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260003
PNG
(CHEMBL4088791)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN=[N+]=[N-] |r|
Show InChI InChI=1S/C13H15ClN4O4/c14-9-4-2-1-3-8(9)12(20)16-5-10-11(19)13(21,7-22-10)6-17-18-15/h1-4,10-11,19,21H,5-7H2,(H,16,20)/t10-,11-,13+/m1/s1
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n/an/an/an/a 1.51E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259994
PNG
(CHEMBL4060563)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CN1Cc2ccccc2C1=O |r|
Show InChI InChI=1S/C21H21ClN2O5/c22-16-8-4-3-7-15(16)19(26)23-9-17-18(25)21(28,12-29-17)11-24-10-13-5-1-2-6-14(13)20(24)27/h1-8,17-18,25,28H,9-12H2,(H,23,26)/t17-,18-,21+/m1/s1
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n/an/an/an/a 1.37E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259996
PNG
(CHEMBL4085383)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2)OC[C@@]1(O)CNC(=O)c1ccccc1Cl |r|
Show InChI InChI=1S/C20H21ClN2O5/c21-15-9-5-4-8-14(15)19(26)23-11-20(27)12-28-16(17(20)24)10-22-18(25)13-6-2-1-3-7-13/h1-9,16-17,24,27H,10-12H2,(H,22,25)(H,23,26)/t16-,17-,20+/m1/s1
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n/an/an/an/a 1.50E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259998
PNG
(CHEMBL4077423)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C20H21ClN2O5/c21-15-9-5-4-8-14(15)19(26)22-10-16-17(24)20(27,12-28-16)11-23-18(25)13-6-2-1-3-7-13/h1-9,16-17,24,27H,10-12H2,(H,22,26)(H,23,25)/t16-,17-,20+/m1/s1
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n/an/an/an/a 7.98E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259987
PNG
(CHEMBL4082179)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1F |r|
Show InChI InChI=1S/C20H20ClFN2O5/c21-14-7-3-1-5-12(14)18(26)23-9-16-17(25)20(28,11-29-16)10-24-19(27)13-6-2-4-8-15(13)22/h1-8,16-17,25,28H,9-11H2,(H,23,26)(H,24,27)/t16-,17-,20+/m1/s1
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n/an/an/an/a 6.22E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260006
PNG
(CHEMBL4078565)
Show SMILES O[C@@H]1[C@@H](CN2C(=O)c3ccccc3C2=O)OC[C@@]1(O)CNC(=O)c1ccccc1Cl |r|
Show InChI InChI=1S/C21H19ClN2O6/c22-15-8-4-3-7-14(15)18(26)23-10-21(29)11-30-16(17(21)25)9-24-19(27)12-5-1-2-6-13(12)20(24)28/h1-8,16-17,25,29H,9-11H2,(H,23,26)/t16-,17-,21+/m1/s1
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n/an/an/an/a 1.27E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259988
PNG
(CHEMBL4078108)
Show SMILES O[C@H]1CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C12H14ClNO4/c13-8-4-2-1-3-7(8)12(17)14-5-10-11(16)9(15)6-18-10/h1-4,9-11,15-16H,5-6H2,(H,14,17)/t9-,10+,11-/m0/s1
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n/an/an/an/a 4.99E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50260004
PNG
(CHEMBL4079978)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2cnccc2Cl)OC[C@@]1(O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1S/C19H20ClN3O5/c20-14-6-7-21-8-13(14)18(26)22-9-15-16(24)19(27,11-28-15)10-23-17(25)12-4-2-1-3-5-12/h1-8,15-16,24,27H,9-11H2,(H,22,26)(H,23,25)/t15-,16-,19+/m1/s1
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n/an/an/an/a>2.50E+5n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity cotreated wit...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259993
PNG
(CHEMBL4097749)
Show SMILES O[C@@H]1[C@@H](CNC(=O)c2ccccc2Cl)OC[C@@]1(O)CNC(=O)C1CCCCC1 |r|
Show InChI InChI=1S/C20H27ClN2O5/c21-15-9-5-4-8-14(15)19(26)22-10-16-17(24)20(27,12-28-16)11-23-18(25)13-6-2-1-3-7-13/h4-5,8-9,13,16-17,24,27H,1-3,6-7,10-12H2,(H,22,26)(H,23,25)/t16-,17-,20+/m1/s1
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n/an/an/an/a 9.56E+3n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair
Signal transduction protein TRAP


(Staphylococcus aureus (strain Mu50 / ATCC 700699))		BDBM50259988
PNG
(CHEMBL4078108)
Show SMILES O[C@H]1CO[C@H](CNC(=O)c2ccccc2Cl)[C@H]1O |r|
Show InChI InChI=1S/C12H14ClNO4/c13-8-4-2-1-3-7(8)12(17)14-5-10-11(16)9(15)6-18-10/h1-4,9-11,15-16H,5-6H2,(H,14,17)/t9-,10+,11-/m0/s1
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n/an/an/an/a 1.14E+4n/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of methicillin-resistant Staphylococcus aureus Mu50 TRAP assessed as potentiation of vancomycin-induced antibiofilm activity treated for 4...

ACS Med Chem Lett 8: 38-42 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00315
BindingDB Entry DOI: 10.7270/Q2RR21QM
More data for this
Ligand-Target Pair