Compile Data Set for Download or QSAR

Found 78 hits with Last Name = 'yousuf' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50102692 (4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCC1)N(C)C Show InChI InChI=1S/C24H32N2O4/c1-26(2)24(12-8-9-13-24)17-25-23(27)19-14-20(28-3)22(21(15-19)29-4)30-16-18-10-6-5-7-11-18/h5-7,10-11,14-15H,8-9,12-13,16-17H2,1-4H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50102692 (4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCC1)N(C)C Show InChI InChI=1S/C24H32N2O4/c1-26(2)24(12-8-9-13-24)17-25-23(27)19-14-20(28-3)22(21(15-19)29-4)30-16-18-10-6-5-7-11-18/h5-7,10-11,14-15H,8-9,12-13,16-17H2,1-4H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537022 (CHEMBL4587165) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C24H46N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25;/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29);1H/b10-9-;/t22-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537040 (CHEMBL4515597) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCSC)C(O)=O |r| Show InChI InChI=1S/C23H43NO3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(25)24-21(23(26)27)19-20-28-2/h10-11,21H,3-9,12-20H2,1-2H3,(H,24,25)(H,26,27)/b11-10-/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537034 (CHEMBL4572247) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCN)C(O)=O |r| Show InChI InChI=1S/C23H44N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(26)25-21(23(27)28)18-17-20-24;/h9-10,21H,2-8,11-20,24H2,1H3,(H,25,26)(H,27,28);1H/b10-9-;/t21-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537044 (CHEMBL4562565) Show SMILES Cl.Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C24H46N4O3.2ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(29)28-21(23(30)31)18-17-20-27-24(25)26;;/h9-10,21H,2-8,11-20H2,1H3,(H,28,29)(H,30,31)(H4,25,26,27);2*1H/b10-9-;;/t21-;;/m0../s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537033 (CHEMBL4535356) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C24H46N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25;/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29);1H/b10-9-;/t22-;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537043 (CHEMBL4227139) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C29H44N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-28(32)31-27(29(33)34)22-24-23-30-26-20-18-17-19-25(24)26/h9-10,17-20,23,27,30H,2-8,11-16,21-22H2,1H3,(H,31,32)(H,33,34)/b10-9-/t27-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537049 (CHEMBL4527071) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CO)C(O)=O |r| Show InChI InChI=1S/C21H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)22-19(18-23)21(25)26/h9-10,19,23H,2-8,11-18H2,1H3,(H,22,24)(H,25,26)/b10-9-/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537023 (CHEMBL4542099) Show SMILES Cl.Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C24H46N4O3.2ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(29)28-21(23(30)31)18-17-20-27-24(25)26;;/h9-10,21H,2-8,11-20H2,1H3,(H,28,29)(H,30,31)(H4,25,26,27);2*1H/b10-9-;;/t21-;;/m1../s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537054 (CHEMBL4549008) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCCN)C(=O)OC |r| Show InChI InChI=1S/C25H48N2O3.ClH/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-24(28)27-23(25(29)30-2)20-18-19-22-26;/h10-11,23H,3-9,12-22,26H2,1-2H3,(H,27,28);1H/b11-10-;/t23-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50256745 ((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...) Show SMILES N[C@@H](COC(c1cccc(F)c1)c1ccccc1OCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H22FNO4/c24-18-10-6-9-17(13-18)22(29-15-20(25)23(26)27)19-11-4-5-12-21(19)28-14-16-7-2-1-3-8-16/h1-13,20,22H,14-15,25H2,(H,26,27)/t20-,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50023924 (CHEMBL3325507) Show SMILES CN1CCC(CC1)NC(=O)c1ccc(COc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H23F3N2O2/c1-26-12-10-18(11-13-26)25-20(27)16-4-2-15(3-5-16)14-28-19-8-6-17(7-9-19)21(22,23)24/h2-9,18H,10-14H2,1H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537031 (CHEMBL4540633) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O |r| Show InChI InChI=1S/C24H41N3O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(28)27-22(24(29)30)18-21-19-25-20-26-21;/h9-10,19-20,22H,2-8,11-18H2,1H3,(H,25,26)(H,27,28)(H,29,30);1H/b10-9-;/t22-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537017 (CHEMBL4228560) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CC(C)C)C(O)=O |r| Show InChI InChI=1S/C24H45NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)25-22(24(27)28)20-21(2)3/h11-12,21-22H,4-10,13-20H2,1-3H3,(H,25,26)(H,27,28)/b12-11-/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537029 (CHEMBL4592570) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C28H45NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-27(30)29-26(28(31)32)24-23-25-20-17-16-18-21-25/h9-10,16-18,20-21,26H,2-8,11-15,19,22-24H2,1H3,(H,29,30)(H,31,32)/b10-9-/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537045 (CHEMBL4562110) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCN)C(O)=O |r| Show InChI InChI=1S/C22H42N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)24-20(18-19-23)22(26)27;/h9-10,20H,2-8,11-19,23H2,1H3,(H,24,25)(H,26,27);1H/b10-9-;/t20-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537035 (CHEMBL4549529) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CN)C(O)=O |r| Show InChI InChI=1S/C21H40N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)23-19(18-22)21(25)26;/h9-10,19H,2-8,11-18,22H2,1H3,(H,23,24)(H,25,26);1H/b10-9-;/t19-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537028 (CHEMBL4228763) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C27H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-26(29)28-25(27(30)31)23-24-20-17-16-18-21-24/h9-10,16-18,20-21,25H,2-8,11-15,19,22-23H2,1H3,(H,28,29)(H,30,31)/b10-9-/t25-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537019 (CHEMBL4526987) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCC)C(O)=O |r| Show InChI InChI=1S/C24H45NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-17-18-19-21-23(26)25-22(24(27)28)20-6-4-2/h12-13,22H,3-11,14-21H2,1-2H3,(H,25,26)(H,27,28)/b13-12-/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537048 (CHEMBL4576431) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCSC)C(O)=O |r| Show InChI InChI=1S/C23H43NO3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(25)24-21(23(26)27)19-20-28-2/h10-11,21H,3-9,12-20H2,1-2H3,(H,24,25)(H,26,27)/b11-10-/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537032 (CHEMBL4559571) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](Cc1cnc[nH]1)C(O)=O |r| Show InChI InChI=1S/C24H41N3O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(28)27-22(24(29)30)18-21-19-25-20-26-21;/h9-10,19-20,22H,2-8,11-18H2,1H3,(H,25,26)(H,27,28)(H,29,30);1H/b10-9-;/t22-;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	313	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537046 (CHEMBL4531406) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C |r| Show InChI InChI=1S/C25H47NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4/h12-13,23H,5-11,14-22H2,1-4H3/b13-12-/t23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiology				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537041 (CHEMBL4515758) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C21H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)22-19(18-23)21(25)26/h9-10,19,23H,2-8,11-18H2,1H3,(H,22,24)(H,25,26)/b10-9-/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	496	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537018 (CHEBI:73723 | Oleoyl Glycine) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCC(O)=O Show InChI InChI=1S/C20H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)21-18-20(23)24/h9-10H,2-8,11-18H2,1H3,(H,21,22)(H,23,24)/b10-9-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiology				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537018 (CHEBI:73723 | Oleoyl Glycine) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCC(O)=O Show InChI InChI=1S/C20H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)21-18-20(23)24/h9-10H,2-8,11-18H2,1H3,(H,21,22)(H,23,24)/b10-9-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537036 (CHEMBL4559157) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)NCCCCCN Show InChI InChI=1S/C23H46N2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20-23(26)25-22-19-16-18-21-24/h9-10H,2-8,11-22,24H2,1H3,(H,25,26)/b10-9-	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537024 (CHEBI:17490 | CHEMBL3392050) Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Reversible non-competitive inhibition of human GlyT2a expressed in Xenopus laevis oocytes by two-electrode voltage clamp electrophysiology				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537042 (CHEMBL4526841) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CC(N)=O)C(O)=O |r| Show InChI InChI=1S/C22H40N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(26)24-19(22(27)28)18-20(23)25/h9-10,19H,2-8,11-18H2,1H3,(H2,23,25)(H,24,26)(H,27,28)/b10-9-/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	613	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537025 (CHEMBL4545242) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C22H39NO5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)23-19(22(27)28)18-21(25)26/h9-10,19H,2-8,11-18H2,1H3,(H,23,24)(H,25,26)(H,27,28)/b10-9-/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	865	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537047 (CHEMBL4543598) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C23H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(25)24-22(20(2)3)23(26)27/h11-12,20,22H,4-10,13-19H2,1-3H3,(H,24,25)(H,26,27)/b12-11-/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537038 (CHEMBL4516669) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C23H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(25)24-22(20(2)3)23(26)27/h11-12,20,22H,4-10,13-19H2,1-3H3,(H,24,25)(H,26,27)/b12-11-/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537051 (CHEMBL226397 | Oleoyl L-Alanine) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](C)C(O)=O Show InChI InChI=1S/C21H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20(23)22-19(2)21(24)25/h10-11,19H,3-9,12-18H2,1-2H3,(H,22,23)(H,24,25)/b11-10-/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537050 (CHEMBL4576550) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C22H39NO5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)23-19(22(27)28)18-21(25)26/h9-10,19H,2-8,11-18H2,1H3,(H,23,24)(H,25,26)(H,27,28)/b10-9-/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50537037 (CHEMBL4578795) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](C)C(O)=O |r| Show InChI InChI=1S/C21H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20(23)22-19(2)21(24)25/h10-11,19H,3-9,12-18H2,1-2H3,(H,22,23)(H,24,25)/b11-10-/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537022 (CHEMBL4587165) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C24H46N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25;/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29);1H/b10-9-;/t22-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537031 (CHEMBL4540633) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O |r| Show InChI InChI=1S/C24H41N3O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(28)27-22(24(29)30)18-21-19-25-20-26-21;/h9-10,19-20,22H,2-8,11-18H2,1H3,(H,25,26)(H,27,28)(H,29,30);1H/b10-9-;/t22-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537032 (CHEMBL4559571) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](Cc1cnc[nH]1)C(O)=O |r| Show InChI InChI=1S/C24H41N3O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(28)27-22(24(29)30)18-21-19-25-20-26-21;/h9-10,19-20,22H,2-8,11-18H2,1H3,(H,25,26)(H,27,28)(H,29,30);1H/b10-9-;/t22-;/m1./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537023 (CHEMBL4542099) Show SMILES Cl.Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C24H46N4O3.2ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(29)28-21(23(30)31)18-17-20-27-24(25)26;;/h9-10,21H,2-8,11-20H2,1H3,(H,28,29)(H,30,31)(H4,25,26,27);2*1H/b10-9-;;/t21-;;/m1../s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537033 (CHEMBL4535356) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C24H46N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-23(27)26-22(24(28)29)19-17-18-21-25;/h9-10,22H,2-8,11-21,25H2,1H3,(H,26,27)(H,28,29);1H/b10-9-;/t22-;/m1./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537034 (CHEMBL4572247) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCN)C(O)=O |r| Show InChI InChI=1S/C23H44N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(26)25-21(23(27)28)18-17-20-24;/h9-10,21H,2-8,11-20,24H2,1H3,(H,25,26)(H,27,28);1H/b10-9-;/t21-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537035 (CHEMBL4549529) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CN)C(O)=O |r| Show InChI InChI=1S/C21H40N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)23-19(18-22)21(25)26;/h9-10,19H,2-8,11-18,22H2,1H3,(H,23,24)(H,25,26);1H/b10-9-;/t19-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537036 (CHEMBL4559157) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)NCCCCCN Show InChI InChI=1S/C23H46N2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20-23(26)25-22-19-16-18-21-24/h9-10H,2-8,11-22,24H2,1H3,(H,25,26)/b10-9-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537048 (CHEMBL4576431) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CCSC)C(O)=O |r| Show InChI InChI=1S/C23H43NO3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(25)24-21(23(26)27)19-20-28-2/h10-11,21H,3-9,12-20H2,1-2H3,(H,24,25)(H,26,27)/b11-10-/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537049 (CHEMBL4527071) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CO)C(O)=O |r| Show InChI InChI=1S/C21H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)22-19(18-23)21(25)26/h9-10,19,23H,2-8,11-18H2,1H3,(H,22,24)(H,25,26)/b10-9-/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537044 (CHEMBL4562565) Show SMILES Cl.Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C24H46N4O3.2ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(29)28-21(23(30)31)18-17-20-27-24(25)26;;/h9-10,21H,2-8,11-20H2,1H3,(H,28,29)(H,30,31)(H4,25,26,27);2*1H/b10-9-;;/t21-;;/m0../s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537045 (CHEMBL4562110) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCN)C(O)=O |r| Show InChI InChI=1S/C22H42N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)24-20(18-19-23)22(26)27;/h9-10,20H,2-8,11-19,23H2,1H3,(H,24,25)(H,26,27);1H/b10-9-;/t20-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537041 (CHEMBL4515758) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C21H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)22-19(18-23)21(25)26/h9-10,19,23H,2-8,11-18H2,1H3,(H,22,24)(H,25,26)/b10-9-/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537054 (CHEMBL4549008) Show SMILES Cl.CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCCCN)C(=O)OC |r| Show InChI InChI=1S/C25H48N2O3.ClH/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-24(28)27-23(25(29)30-2)20-18-19-22-26;/h10-11,23H,3-9,12-22,26H2,1-2H3,(H,27,28);1H/b11-10-;/t23-;/m0./s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50537040 (CHEMBL4515597) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCSC)C(O)=O |r| Show InChI InChI=1S/C23H43NO3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(25)24-21(23(26)27)19-20-28-2/h10-11,21H,3-9,12-20H2,1-2H3,(H,24,25)(H,26,27)/b11-10-/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...				J Med Chem 62: 2466-2484 (2019) Article DOI: 10.1021/acs.jmedchem.8b01775 BindingDB Entry DOI: 10.7270/Q21R6V1K
					More data for this Ligand-Target Pair

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