Compile Data Set for Download or QSAR

Found 2522 hits with Last Name = 'joseph' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454823 (CHEMBL3084910) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1Cl)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24ClNO/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454830 (CHEMBL3084869) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1F)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24FNO/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454825 (CHEMBL3084878) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1C)N2C |TLB:9:7:24:3.2| Show InChI InChI=1S/C22H27NO/c1-16-8-6-7-11-21(16)22(17-9-4-3-5-10-17)24-20-14-18-12-13-19(15-20)23(18)2/h3-11,18-20,22H,12-15H2,1-2H3/t18-,19+,20+,22?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50366775 (BENZTROPINE | Benzatropine) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Muscarinic receptor from rat brain membranes using [3H]pirenzepine				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50366775 (BENZTROPINE | Benzatropine) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454828 (CHEMBL3084907) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(F)c1)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24FNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454824 (CHEMBL3084909) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1cccc(F)c1)c1cccc(F)c1)N2C |TLB:9:7:25:2.3| Show InChI InChI=1S/C21H23F2NO/c1-24-18-8-9-19(24)13-20(12-18)25-21(14-4-2-6-16(22)10-14)15-5-3-7-17(23)11-15/h2-7,10-11,18-21H,8-9,12-13H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454829 (CHEMBL3084870) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(Cl)c1)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24ClNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454827 (AMINOBENZTROPINE) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1N)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H26N2O/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14,22H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM86702 (3-[(4-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(Cl)cc1 |THB:9:7:1:3.4| Show InChI InChI=1S/C21H24ClNO/c1-23-18-11-12-19(23)14-20(13-18)24-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50454826 (CHEMBL3084901) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(c1)C(F)(F)F)N2C |TLB:9:7:27:2.3| Show InChI InChI=1S/C22H24F3NO/c1-26-18-10-11-19(26)14-20(13-18)27-21(15-6-3-2-4-7-15)16-8-5-9-17(12-16)22(23,24)25/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes.				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22167 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496111 (CHEMBL3121424) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 Show InChI InChI=1S/C30H29N3O/c1-34-30-16-7-6-14-29(30)32-19-17-31(18-20-32)21-24-22-33(27-13-5-4-12-26(24)27)28-15-8-10-23-9-2-3-11-25(23)28/h2-16,22H,17-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496112 (CHEMBL3121422) Show SMILES COc1ccccc1N1CCN(Cc2cn(-c3cccc(C)c3C)c3ccccc23)CC1 Show InChI InChI=1S/C28H31N3O/c1-21-9-8-13-25(22(21)2)31-20-23(24-10-4-5-11-26(24)31)19-29-15-17-30(18-16-29)27-12-6-7-14-28(27)32-3/h4-14,20H,15-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496117 (CHEMBL3121438) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccc3C)c3ccccc23)CC1 Show InChI InChI=1S/C27H29N3O/c1-21-9-3-5-11-24(21)30-20-22(23-10-4-6-12-25(23)30)19-28-15-17-29(18-16-28)26-13-7-8-14-27(26)31-2/h3-14,20H,15-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496104 (CHEMBL3121435) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c3ccccc23)CC1 Show InChI InChI=1S/C26H27N3O/c1-30-26-14-8-7-13-25(26)28-17-15-27(16-18-28)19-21-20-29(22-9-3-2-4-10-22)24-12-6-5-11-23(21)24/h2-14,20H,15-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496104 (CHEMBL3121435) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c3ccccc23)CC1 Show InChI InChI=1S/C26H27N3O/c1-30-26-14-8-7-13-25(26)28-17-15-27(16-18-28)19-21-20-29(22-9-3-2-4-10-22)24-12-6-5-11-23(21)24/h2-14,20H,15-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496108 (CHEMBL3121419) Show SMILES OC(=O)\C=C\C(O)=O.CC(C)c1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C28H31N3/c1-22(2)25-12-6-8-14-27(25)31-21-23(26-13-7-9-15-28(26)31)20-29-16-18-30(19-17-29)24-10-4-3-5-11-24/h3-15,21-22H,16-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496117 (CHEMBL3121438) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccc3C)c3ccccc23)CC1 Show InChI InChI=1S/C27H29N3O/c1-21-9-3-5-11-24(21)30-20-22(23-10-4-6-12-25(23)30)19-28-15-17-29(18-16-28)26-13-7-8-14-27(26)31-2/h3-14,20H,15-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496103 (CHEMBL3121436) Show SMILES OC(=O)\C=C\C(O)=O.Oc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c3ccccc23)CC1 Show InChI InChI=1S/C25H25N3O/c29-25-13-7-6-12-24(25)27-16-14-26(15-17-27)18-20-19-28(21-8-2-1-3-9-21)23-11-5-4-10-22(20)23/h1-13,19,29H,14-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496112 (CHEMBL3121422) Show SMILES COc1ccccc1N1CCN(Cc2cn(-c3cccc(C)c3C)c3ccccc23)CC1 Show InChI InChI=1S/C28H31N3O/c1-21-9-8-13-25(22(21)2)31-20-23(24-10-4-5-11-26(24)31)19-29-15-17-30(18-16-29)27-12-6-7-14-28(27)32-3/h4-14,20H,15-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496113 (CHEMBL3121420) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccc3C(C)C)c3ccccc23)CC1 Show InChI InChI=1S/C29H33N3O/c1-22(2)24-10-4-6-12-26(24)32-21-23(25-11-5-7-13-27(25)32)20-30-16-18-31(19-17-30)28-14-8-9-15-29(28)33-3/h4-15,21-22H,16-20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496126 (CHEMBL3121421) Show SMILES OC(=O)\C=C\C(O)=O.Cc1cccc(c1C)-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C27H29N3/c1-21-9-8-14-26(22(21)2)30-20-23(25-12-6-7-13-27(25)30)19-28-15-17-29(18-16-28)24-10-4-3-5-11-24/h3-14,20H,15-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496129 (CHEMBL3121437) Show SMILES OC(=O)\C=C\C(O)=O.Cc1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H27N3/c1-21-9-5-7-13-25(21)29-20-22(24-12-6-8-14-26(24)29)19-27-15-17-28(18-16-27)23-10-3-2-4-11-23/h2-14,20H,15-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50106320 (3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethylidene}-8...) Show SMILES CN1C2CCC1CC(C2)=CCOC(c1ccc(F)cc1)c1ccc(F)cc1 |THB:9:7:1:3.4| Show InChI InChI=1S/C23H25F2NO/c1-26-21-10-11-22(26)15-16(14-21)12-13-27-23(17-2-6-19(24)7-3-17)18-4-8-20(25)9-5-18/h2-9,12,21-23H,10-11,13-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50106316 (3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(3-p...) Show SMILES Fc1ccc(cc1)C(OCCC1CC2CCC(C1)N2CCCc1ccccc1)c1ccc(F)cc1 |TLB:10:11:18:14.15| Show InChI InChI=1S/C31H35F2NO/c32-27-12-8-25(9-13-27)31(26-10-14-28(33)15-11-26)35-20-18-24-21-29-16-17-30(22-24)34(29)19-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,24,29-31H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496110 (CHEMBL3121427) Show SMILES OC(=O)\C=C\C(O)=O.FC(F)(F)c1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H24F3N3/c27-26(28,29)23-11-5-7-13-25(23)32-19-20(22-10-4-6-12-24(22)32)18-30-14-16-31(17-15-30)21-8-2-1-3-9-21/h1-13,19H,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496101 (CHEMBL3121425) Show SMILES OC(=O)\C=C\C(O)=O.Oc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 Show InChI InChI=1S/C29H27N3O/c33-29-15-6-5-13-28(29)31-18-16-30(17-19-31)20-23-21-32(26-12-4-3-11-25(23)26)27-14-7-9-22-8-1-2-10-24(22)27/h1-15,21,33H,16-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to 5HT7 receptor (unknown origin)				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454829 (CHEMBL3084870) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1cccc(Cl)c1)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24ClNO/c1-23-18-10-11-19(23)14-20(13-18)24-21(15-6-3-2-4-7-15)16-8-5-9-17(22)12-16/h2-9,12,18-21H,10-11,13-14H2,1H3/t18-,19+,20+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496103 (CHEMBL3121436) Show SMILES OC(=O)\C=C\C(O)=O.Oc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c3ccccc23)CC1 Show InChI InChI=1S/C25H25N3O/c29-25-13-7-6-12-24(25)27-16-14-26(15-17-27)18-20-19-28(21-8-2-1-3-9-21)23-11-5-4-10-22(20)23/h1-13,19,29H,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50106314 (3-(2-Benzhydryloxy-ethyl)-8-(3-phenyl-propyl)-8-az...) Show SMILES C(CN1C2CCC1CC(CCOC(c1ccccc1)c1ccccc1)C2)Cc1ccccc1 |THB:9:8:2:4.5| Show InChI InChI=1S/C31H37NO/c1-4-11-25(12-5-1)13-10-21-32-29-18-19-30(32)24-26(23-29)20-22-33-31(27-14-6-2-7-15-27)28-16-8-3-9-17-28/h1-9,11-12,14-17,26,29-31H,10,13,18-24H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50106321 (CHEMBL126992 | N-Benzhydryl-2-(8-methyl-8-aza-bicy...) Show SMILES CN1C2CCC1CC(CC(=O)NC(c1ccccc1)c1ccccc1)C2 |TLB:0:1:7.25.6:3.4,THB:8:7:1:3.4| Show InChI InChI=1S/C23H28N2O/c1-25-20-12-13-21(25)15-17(14-20)16-22(26)24-23(18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-11,17,20-21,23H,12-16H2,1H3,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86702 (3-[(4-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) Show SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccc(Cl)cc1 |THB:9:7:1:3.4| Show InChI InChI=1S/C21H24ClNO/c1-23-18-11-12-19(23)14-20(13-18)24-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16/h2-10,18-21H,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496121 (CHEMBL3121412) Show SMILES OC(=O)\C=C\C(O)=O.Cc1ccccc1-n1cc(CN2CCC(=CC2)c2ccccc2)c2ccccc12 |c:22| Show InChI InChI=1S/C27H26N2/c1-21-9-5-7-13-26(21)29-20-24(25-12-6-8-14-27(25)29)19-28-17-15-23(16-18-28)22-10-3-2-4-11-22/h2-15,20H,16-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496125 (CHEMBL3121423) Show SMILES OC(=O)\C=C\C(O)=O.C(N1CCN(CC1)c1ccccc1)c1cn(-c2cccc3ccccc23)c2ccccc12 Show InChI InChI=1S/C29H27N3/c1-2-11-25(12-3-1)31-19-17-30(18-20-31)21-24-22-32(28-15-7-6-14-27(24)28)29-16-8-10-23-9-4-5-13-26(23)29/h1-16,22H,17-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496107 (CHEMBL3121429) Show SMILES OC(=O)\C=C\C(O)=O.N#Cc1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H24N4/c27-18-21-8-4-6-12-25(21)30-20-22(24-11-5-7-13-26(24)30)19-28-14-16-29(17-15-28)23-9-2-1-3-10-23/h1-13,20H,14-17,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50142891 (2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...) Show SMILES COc1ccc(Br)cc1CCc1ccccc1C1=NCCN1 |t:19| Show InChI InChI=1S/C18H19BrN2O/c1-22-17-9-8-15(19)12-14(17)7-6-13-4-2-3-5-16(13)18-20-10-11-21-18/h2-5,8-9,12H,6-7,10-11H2,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...				J Med Chem 47: 1602-4 (2004) Article DOI: 10.1021/jm034244g BindingDB Entry DOI: 10.7270/Q2JQ10GG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor (unknown origin)				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496107 (CHEMBL3121429) Show SMILES OC(=O)\C=C\C(O)=O.N#Cc1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H24N4/c27-18-21-8-4-6-12-25(21)30-20-22(24-11-5-7-13-26(24)30)19-28-14-16-29(17-15-28)23-9-2-1-3-10-23/h1-13,20H,14-17,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454824 (CHEMBL3084909) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1cccc(F)c1)c1cccc(F)c1)N2C |TLB:9:7:25:2.3| Show InChI InChI=1S/C21H23F2NO/c1-24-18-8-9-19(24)13-20(12-18)25-21(14-4-2-6-16(22)10-14)15-5-3-7-17(23)11-15/h2-7,10-11,18-21H,8-9,12-13H2,1H3/t18-,19+,20+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496102 (CHEMBL3121417) Show SMILES OC(=O)\C=C\C(O)=O.CCc1ccccc1-n1cc(CN2CCN(CC2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C27H29N3/c1-2-22-10-6-8-14-26(22)30-21-23(25-13-7-9-15-27(25)30)20-28-16-18-29(19-17-28)24-11-4-3-5-12-24/h3-15,21H,2,16-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454830 (CHEMBL3084869) Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1F)N2C |TLB:9:7:24:2.3| Show InChI InChI=1S/C21H24FNO/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14H2,1H3/t16-,17+,18+,21?	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen				J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM23772 ((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...) Show SMILES N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	50	-41.3	n/a	n/a	n/a	n/a	n/a	6.9	22
Institut de Biologie Structurale					Assay Description The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...				J Med Chem 51: 1115-25 (2008) Article DOI: 10.1021/jm070606z BindingDB Entry DOI: 10.7270/Q2DJ5CXD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50106319 (3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-meth...) Show SMILES CN1C2CCC1CC(CCOC(c1ccc(F)cc1)c1ccc(F)cc1)C2 |THB:8:7:1:3.4| Show InChI InChI=1S/C23H27F2NO/c1-26-21-10-11-22(26)15-16(14-21)12-13-27-23(17-2-6-19(24)7-3-17)18-4-8-20(25)9-5-18/h2-9,16,21-23H,10-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [125]RTI-55				J Med Chem 44: 3937-45 (2001) BindingDB Entry DOI: 10.7270/Q26Q1XZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50496106 (CHEMBL3121434) Show SMILES OC(=O)\C=C\C(O)=O.C(N1CCN(CC1)c1ccccc1)c1cn(-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H25N3/c1-3-9-22(10-4-1)27-17-15-26(16-18-27)19-21-20-28(23-11-5-2-6-12-23)25-14-8-7-13-24(21)25/h1-14,20H,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from cloned human 5HT7B receptor expressed in HEK293 cells after 1 hr by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50496105 (CHEMBL3121431) Show SMILES OC(=O)\C=C\C(O)=O.COc1ccccc1N1CCN(Cc2cn(-c3ccccn3)c3ccccc23)CC1 Show InChI InChI=1S/C25H26N4O/c1-30-24-11-5-4-10-23(24)28-16-14-27(15-17-28)18-20-19-29(25-12-6-7-13-26-25)22-9-3-2-8-21(20)22/h2-13,19H,14-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat hippocampus homogenates after 15 mins by scintillation counting				Eur J Med Chem 75: 159-68 (2014) Article DOI: 10.1016/j.ejmech.2014.01.055 BindingDB Entry DOI: 10.7270/Q24J0J3B
					More data for this Ligand-Target Pair

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