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Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'zanoni' and Initial = 'bc'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50073048
PNG
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1
Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34)
KEGG

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n/an/a 0.470n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound against human Neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103722
PNG
(CHEMBL3084802 | N-{4-[5-Amino-1-(3-trifluoromethyl...)
Show SMILES Nc1cc(nn1-c1cccc(c1)C(F)(F)F)C1CCC(CNS(=O)(=O)c2ccccc2[N+]([O-])=O)CC1 |(.85,-2.45,;1.97,-1.38,;3.48,-1.66,;4.21,-.31,;3.16,.79,;1.77,.14,;.43,.88,;.38,2.42,;-.97,3.16,;-2.28,2.36,;-2.24,.81,;-.9,.07,;-3.57,.02,;-4.77,-.71,;-5.08,.55,;-3.79,-1.59,;5.75,-.12,;6.33,1.3,;7.84,1.51,;8.79,.27,;10.32,.48,;10.9,1.89,;12.43,2.09,;11.62,3.41,;13.48,3.22,;13.27,.79,;12.56,-.57,;13.39,-1.87,;14.93,-1.8,;15.63,-.4,;14.79,.88,;15.49,2.24,;17.03,2.32,;14.65,3.54,;8.19,-1.15,;6.68,-1.34,)|
Show InChI InChI=1S/C23H24F3N5O4S/c24-23(25,26)17-4-3-5-18(12-17)30-22(27)13-19(29-30)16-10-8-15(9-11-16)14-28-36(34,35)21-7-2-1-6-20(21)31(32)33/h1-7,12-13,15-16,28H,8-11,14,27H2
KEGG

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n/an/a 10n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103700
PNG
(CHEMBL3084801 | N-{4-[5-Amino-1-(4-trifluoromethyl...)
Show SMILES Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)C1CCC(CNS(=O)(=O)c2ccccc2[N+]([O-])=O)CC1 |(-4.59,.2,;-3.68,1.44,;-2.14,1.44,;-1.67,2.91,;-2.91,3.81,;-4.16,2.91,;-5.61,3.39,;-6.75,2.35,;-8.22,2.82,;-8.54,4.35,;-7.4,5.36,;-5.93,4.88,;-10.01,4.82,;-10.59,6.31,;-11.33,3.93,;-11.32,5.23,;-.2,3.39,;.12,4.89,;1.59,5.36,;2.73,4.33,;4.19,4.79,;5.32,3.77,;6.79,4.23,;7.11,5.72,;8.28,4.63,;7.93,3.19,;7.6,1.69,;8.74,.67,;10.2,1.13,;10.53,2.63,;9.39,3.67,;9.7,5.16,;11.16,5.64,;8.56,6.21,;2.4,2.82,;.94,2.35,)|
Show InChI InChI=1S/C23H24F3N5O4S/c24-23(25,26)17-9-11-18(12-10-17)30-22(27)13-19(29-30)16-7-5-15(6-8-16)14-28-36(34,35)21-4-2-1-3-20(21)31(32)33/h1-4,9-13,15-16,28H,5-8,14,27H2
KEGG

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n/an/a 10n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103712
PNG
(CHEMBL430414 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H22N4O3S/c1-16-3-9-19(10-4-16)27-23(24)15-22(25-27)17-5-7-18(8-6-17)26-31(28,29)21-13-11-20(30-2)12-14-21/h3-15,26H,24H2,1-2H3
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n/an/a 15n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103712
PNG
(CHEMBL430414 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H22N4O3S/c1-16-3-9-19(10-4-16)27-23(24)15-22(25-27)17-5-7-18(8-6-17)26-31(28,29)21-13-11-20(30-2)12-14-21/h3-15,26H,24H2,1-2H3
KEGG

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n/an/a 15n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103715
PNG
(2-Amino-N-{4-[5-amino-1-(4-trifluoromethyl-phenyl)...)
Show SMILES Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)C1CCC(CNS(=O)(=O)c2ccccc2N)CC1 |(-4.59,.2,;-3.68,1.44,;-2.14,1.44,;-1.67,2.91,;-2.91,3.81,;-4.16,2.91,;-5.61,3.39,;-5.93,4.88,;-7.4,5.36,;-8.54,4.35,;-8.22,2.82,;-6.75,2.35,;-10.01,4.82,;-10.59,6.31,;-11.33,3.93,;-11.32,5.23,;-.2,3.39,;.12,4.89,;1.59,5.36,;2.73,4.33,;4.19,4.79,;5.32,3.77,;6.79,4.23,;7.11,5.72,;8.28,4.63,;7.93,3.19,;7.6,1.69,;8.74,.67,;10.2,1.13,;10.53,2.63,;9.39,3.67,;9.7,5.16,;2.4,2.82,;.94,2.35,)|
Show InChI InChI=1S/C23H26F3N5O2S/c24-23(25,26)17-9-11-18(12-10-17)31-22(28)13-20(30-31)16-7-5-15(6-8-16)14-29-34(32,33)21-4-2-1-3-19(21)27/h1-4,9-13,15-16,29H,5-8,14,27-28H2
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n/an/a 20n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103708
PNG
(CHEMBL75823 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C22H20N4O2S/c1-16-7-13-19(14-8-16)26-22(23)15-21(24-26)17-9-11-18(12-10-17)25-29(27,28)20-5-3-2-4-6-20/h2-15,25H,23H2,1H3
KEGG

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n/an/a 25n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103691
PNG
(CHEMBL72547 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C22H19FN4O2S/c1-15-2-10-19(11-3-15)27-22(24)14-21(25-27)16-4-8-18(9-5-16)26-30(28,29)20-12-6-17(23)7-13-20/h2-14,26H,24H2,1H3
KEGG

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n/an/a 29n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103694
PNG
(CHEMBL73643 | N-{4-[5-Amino-1-(3-dimethylamino-phe...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1cccc(c1)N(C)C
Show InChI InChI=1S/C24H25N5O3S/c1-28(2)19-5-4-6-20(15-19)29-24(25)16-23(26-29)17-7-9-18(10-8-17)27-33(30,31)22-13-11-21(32-3)12-14-22/h4-16,27H,25H2,1-3H3
KEGG

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n/an/a 30n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103692
PNG
(CHEMBL73401 | N-{4-[5-Amino-1-(4-fluoro-phenyl)-1H...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C22H19FN4O3S/c1-30-19-10-12-20(13-11-19)31(28,29)26-17-6-2-15(3-7-17)21-14-22(24)27(25-21)18-8-4-16(23)5-9-18/h2-14,26H,24H2,1H3
KEGG

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n/an/a 37n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103707
PNG
(CHEMBL444319 | N-[4-(5-Amino-1-m-tolyl-1H-pyrazol-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1cccc(C)c1
Show InChI InChI=1S/C23H22N4O3S/c1-16-4-3-5-19(14-16)27-23(24)15-22(25-27)17-6-8-18(9-7-17)26-31(28,29)21-12-10-20(30-2)11-13-21/h3-15,26H,24H2,1-2H3
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n/an/a 37n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103688
PNG
(CHEMBL72133 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C23H22N4O2S/c1-16-3-11-20(12-4-16)27-23(24)15-22(25-27)18-7-9-19(10-8-18)26-30(28,29)21-13-5-17(2)6-14-21/h3-15,26H,24H2,1-2H3
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n/an/a 40n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103690
PNG
(CHEMBL307458 | N-[4-(5-Amino-1-naphthalen-1-yl-1H-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1cccc2ccccc12
Show InChI InChI=1S/C26H22N4O3S/c1-33-21-13-15-22(16-14-21)34(31,32)29-20-11-9-19(10-12-20)24-17-26(27)30(28-24)25-8-4-6-18-5-2-3-7-23(18)25/h2-17,29H,27H2,1H3
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n/an/a 48n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103701
PNG
(CHEMBL75827 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C23H19F3N4O2S/c1-15-2-10-19(11-3-15)30-22(27)14-21(28-30)16-4-8-18(9-5-16)29-33(31,32)20-12-6-17(7-13-20)23(24,25)26/h2-14,29H,27H2,1H3
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n/an/a 63n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103699
PNG
(CHEMBL308110 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1
Show InChI InChI=1S/C23H19F3N4O3S/c1-15-2-8-18(9-3-15)30-22(27)14-21(28-30)16-4-6-17(7-5-16)29-34(31,32)20-12-10-19(11-13-20)33-23(24,25)26/h2-14,29H,27H2,1H3
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n/an/a 67n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103696
PNG
(4-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-p...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(N)cc2)cc1
Show InChI InChI=1S/C22H21N5O2S/c1-15-2-10-19(11-3-15)27-22(24)14-21(25-27)16-4-8-18(9-5-16)26-30(28,29)20-12-6-17(23)7-13-20/h2-14,26H,23-24H2,1H3
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n/an/a 74n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103713
PNG
(CHEMBL73251 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C22H19N5O4S/c1-15-2-8-18(9-3-15)26-22(23)14-21(24-26)16-4-6-17(7-5-16)25-32(30,31)20-12-10-19(11-13-20)27(28)29/h2-14,25H,23H2,1H3
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n/an/a 79n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103733
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc2cnccc12
Show InChI InChI=1S/C21H15F3N4O/c1-13-10-19(27-28(13)16-6-3-5-15(11-16)21(22,23)24)20(29)26-18-7-2-4-14-12-25-9-8-17(14)18/h2-12H,1H3,(H,26,29)
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n/an/a 80n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103716
PNG
(CHEMBL75662 | N-[4-(5-Amino-1-phenyl-1H-pyrazol-3-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccccc1
Show InChI InChI=1S/C22H20N4O3S/c1-29-19-11-13-20(14-12-19)30(27,28)25-17-9-7-16(8-10-17)21-15-22(23)26(24-21)18-5-3-2-4-6-18/h2-15,25H,23H2,1H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103703
PNG
(CHEMBL308508 | N-{4-[5-Amino-1-(4-trifluoromethyl-...)
Show SMILES Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)-c1ccc(CNS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C23H19F3N4O2S/c24-23(25,26)18-10-12-19(13-11-18)30-22(27)14-21(29-30)17-8-6-16(7-9-17)15-28-33(31,32)20-4-2-1-3-5-20/h1-14,28H,15,27H2
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103697
PNG
(CHEMBL75369 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3...)
Show SMILES CN(C)c1cccc(c1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C24H25N5O2S/c1-17-7-13-20(14-8-17)29-24(25)16-23(26-29)18-9-11-19(12-10-18)27-32(30,31)22-6-4-5-21(15-22)28(2)3/h4-16,27H,25H2,1-3H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103721
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H12Cl2F3N3O/c1-10-5-16(17(27)24-14-8-12(19)7-13(20)9-14)25-26(10)15-4-2-3-11(6-15)18(21,22)23/h2-9H,1H3,(H,24,27)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103693
PNG
(CHEMBL432352 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C24H25N5O2S/c1-17-4-10-21(11-5-17)29-24(25)16-23(26-29)18-6-8-19(9-7-18)27-32(30,31)22-14-12-20(13-15-22)28(2)3/h4-16,27H,25H2,1-3H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103711
PNG
(CHEMBL307901 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccccc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C22H19N5O4S/c1-15-6-12-18(13-7-15)26-22(23)14-19(24-26)16-8-10-17(11-9-16)25-32(30,31)21-5-3-2-4-20(21)27(28)29/h2-14,25H,23H2,1H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103720
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc2CCCCc12
Show InChI InChI=1S/C22H20F3N3O/c1-14-12-20(27-28(14)17-9-5-8-16(13-17)22(23,24)25)21(29)26-19-11-4-7-15-6-2-3-10-18(15)19/h4-5,7-9,11-13H,2-3,6,10H2,1H3,(H,26,29)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103718
PNG
(5-Methyl-1-m-tolyl-1H-pyrazole-3-carboxylic acid (...)
Show SMILES Cc1cc(nn1-c1cccc(C)c1)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H15Cl2N3O/c1-11-4-3-5-16(6-11)23-12(2)7-17(22-23)18(24)21-15-9-13(19)8-14(20)10-15/h3-10H,1-2H3,(H,21,24)
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n/an/a 218n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103689
PNG
(2-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-p...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccccc2N)cc1
Show InChI InChI=1S/C22H21N5O2S/c1-15-6-12-18(13-7-15)27-22(24)14-20(25-27)16-8-10-17(11-9-16)26-30(28,29)21-5-3-2-4-19(21)23/h2-14,26H,23-24H2,1H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103742
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C21H15F3N4O/c1-13-11-19(27-28(13)15-6-2-5-14(12-15)21(22,23)24)20(29)26-18-9-3-8-17-16(18)7-4-10-25-17/h2-12H,1H3,(H,26,29)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103731
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1c(F)cccc1F
Show InChI InChI=1S/C18H12F5N3O/c1-10-8-15(17(27)24-16-13(19)6-3-7-14(16)20)25-26(10)12-5-2-4-11(9-12)18(21,22)23/h2-9H,1H3,(H,24,27)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103727
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1Nc1ccccc1
Show InChI InChI=1S/C24H19F3N4O/c1-16-14-22(30-31(16)19-11-7-8-17(15-19)24(25,26)27)23(32)29-21-13-6-5-12-20(21)28-18-9-3-2-4-10-18/h2-15,28H,1H3,(H,29,32)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103737
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1Cc1ccccc1
Show InChI InChI=1S/C25H20F3N3O/c1-17-14-23(30-31(17)21-12-7-11-20(16-21)25(26,27)28)24(32)29-22-13-6-5-10-19(22)15-18-8-3-2-4-9-18/h2-14,16H,15H2,1H3,(H,29,32)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103709
PNG
(3-Amino-N-[4-(5-amino-1-p-tolyl-1H-pyrazol-3-yl)-p...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2cccc(N)c2)cc1
Show InChI InChI=1S/C22H21N5O2S/c1-15-5-11-19(12-6-15)27-22(24)14-21(25-27)16-7-9-18(10-8-16)26-30(28,29)20-4-2-3-17(23)13-20/h2-14,26H,23-24H2,1H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103724
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C22H16F3N3O/c1-14-12-20(27-28(14)17-9-5-8-16(13-17)22(23,24)25)21(29)26-19-11-4-7-15-6-2-3-10-18(15)19/h2-13H,1H3,(H,26,29)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103736
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C18H13BrF3N3O/c1-11-8-16(17(26)23-14-6-3-5-13(19)10-14)24-25(11)15-7-2-4-12(9-15)18(20,21)22/h2-10H,1H3,(H,23,26)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103741
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C19H13F6N3O2/c1-11-8-16(27-28(11)14-6-2-4-12(9-14)18(20,21)22)17(29)26-13-5-3-7-15(10-13)30-19(23,24)25/h2-10H,1H3,(H,26,29)
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103710
PNG
(CHEMBL307462 | N-[4-(5-Amino-1-pyridin-2-yl-1H-pyr...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1ccccn1
Show InChI InChI=1S/C21H19N5O3S/c1-29-17-9-11-18(12-10-17)30(27,28)25-16-7-5-15(6-8-16)19-14-20(22)26(24-19)21-4-2-3-13-23-21/h2-14,25H,22H2,1H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103702
PNG
(4-Dimethylamino-N-[4-(5-methylamino-1-p-tolyl-1H-p...)
Show SMILES CNc1cc(nn1-c1ccc(C)cc1)-c1ccc(NS(=O)(=O)c2ccc(cc2)N(C)C)cc1
Show InChI InChI=1S/C25H27N5O2S/c1-18-5-11-22(12-6-18)30-25(26-2)17-24(27-30)19-7-9-20(10-8-19)28-33(31,32)23-15-13-21(14-16-23)29(3)4/h5-17,26,28H,1-4H3
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The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103726
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C18H13ClF3N3O/c1-11-8-16(17(26)23-14-6-3-5-13(19)10-14)24-25(11)15-7-2-4-12(9-15)18(20,21)22/h2-10H,1H3,(H,23,26)
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n/an/a 520n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103744
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1C
Show InChI InChI=1S/C19H16F3N3O/c1-12-6-3-4-9-16(12)23-18(26)17-10-13(2)25(24-17)15-8-5-7-14(11-15)19(20,21)22/h3-11H,1-2H3,(H,23,26)
KEGG

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n/an/a 573n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103735
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C19H16F3N3O/c1-12-5-3-7-15(9-12)23-18(26)17-10-13(2)25(24-17)16-8-4-6-14(11-16)19(20,21)22/h3-11H,1-2H3,(H,23,26)
KEGG

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n/an/a 622n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103730
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(I)c1
Show InChI InChI=1S/C18H13F3IN3O/c1-11-8-16(17(26)23-14-6-3-5-13(22)10-14)24-25(11)15-7-2-4-12(9-15)18(19,20)21/h2-10H,1H3,(H,23,26)
KEGG

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n/an/a 670n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103714
PNG
(3-{5-Amino-3-[4-(4-methoxy-benzenesulfonylamino)-p...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1c[n+](ccn1)C(F)(F)F
Show InChI InChI=1S/C21H18F3N6O3S/c1-33-16-6-8-17(9-7-16)34(31,32)28-15-4-2-14(3-5-15)18-12-19(25)30(27-18)20-13-29(11-10-26-20)21(22,23)24/h2-13,28H,25H2,1H3/q+1
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n/an/a 709n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103723
PNG
(5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid (3...)
Show SMILES Cc1cc(nn1-c1ccccc1)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C17H13Cl2N3O/c1-11-7-16(21-22(11)15-5-3-2-4-6-15)17(23)20-14-9-12(18)8-13(19)10-14/h2-10H,1H3,(H,20,23)
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n/an/a 759n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103729
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1-n1cccc1
Show InChI InChI=1S/C22H17F3N4O/c1-15-13-19(27-29(15)17-8-6-7-16(14-17)22(23,24)25)21(30)26-18-9-2-3-10-20(18)28-11-4-5-12-28/h2-14H,1H3,(H,26,30)
KEGG

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n/an/a 763n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103745
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C18H13F4N3O/c1-11-9-16(17(26)23-14-7-5-13(19)6-8-14)24-25(11)15-4-2-3-12(10-15)18(20,21)22/h2-10H,1H3,(H,23,26)
KEGG

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n/an/a 800n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103706
PNG
(CHEMBL306111 | N-[3-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)-c1cc(N)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H22N4O3S/c1-16-6-8-19(9-7-16)27-23(24)15-22(25-27)17-4-3-5-18(14-17)26-31(28,29)21-12-10-20(30-2)11-13-21/h3-15,26H,24H2,1-2H3
KEGG

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n/an/a>1.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103728
PNG
(5-Methyl-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1ccc(cc1)C(F)(F)F)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H12Cl2F3N3O/c1-10-6-16(17(27)24-14-8-12(19)7-13(20)9-14)25-26(10)15-4-2-11(3-5-15)18(21,22)23/h2-9H,1H3,(H,24,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103705
PNG
(CHEMBL72742 | N-{4-[5-Amino-1-(4-trifluoromethyl-p...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1cc(N)n(n1)-c1cc(ccn1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N5O3S/c1-33-17-6-8-18(9-7-17)34(31,32)29-16-4-2-14(3-5-16)19-13-20(26)30(28-19)21-12-15(10-11-27-21)22(23,24)25/h2-13,29H,26H2,1H3
KEGG

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n/an/a>1.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103732
PNG
(5-Methyl-1-thiophen-2-yl-1H-pyrazole-3-carboxylic ...)
Show SMILES Cc1cc(nn1-c1cccs1)C(=O)Nc1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C15H11Cl2N3OS/c1-9-5-13(19-20(9)14-3-2-4-22-14)15(21)18-12-7-10(16)6-11(17)8-12/h2-8H,1H3,(H,18,21)
KEGG

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n/an/a>1.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))
BDBM50103734
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C18H13ClF3N3O/c1-11-9-16(17(26)23-14-7-5-13(19)6-8-14)24-25(11)15-4-2-3-12(10-15)18(20,21)22/h2-10H,1H3,(H,23,26)
KEGG

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n/an/a>1.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair
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