BindingDB PrimarySearch

Found 9 hits with Last Name = 'yu' and Initial = 'bz'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet-activating factor receptor (Cavia porcellus)	BDBM50021572 ((2S,3S)-2-(3,4-Dimethoxy-phenyl)-3-methyl-5-propyl...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50% of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50405462 (CHEMBL2115332) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50 of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50% of the specific [3H]PAF binding, obtained as natural product.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50% of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition concentration required to block 50% of the specific [3H]PAF binding, obtained from Chiralpak column at low temperatures.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50 %of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50021571 ((2S,3R)-5-Allyl-2-(3,4-dimethoxy-phenyl)-3a-ethoxy...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50 of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM21680 ((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a
University of Delaware Curated by ChEMBL					Assay Description Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...				J Nat Prod 72: 24-8 (2009) Article DOI: 10.1021/np8004453 BindingDB Entry DOI: 10.7270/Q2X34XG0
University of Delaware Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50236230 (2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dih...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Delaware Curated by ChEMBL					Assay Description Binding affinity to human pancreatic recombinant 1B PLA2 expressed in Escherichia coli by resonance energy transfer assay in presence of trimethyl-am...				J Nat Prod 72: 24-8 (2009) Article DOI: 10.1021/np8004453 BindingDB Entry DOI: 10.7270/Q2X34XG0
University of Delaware Curated by ChEMBL					More data for this Ligand-Target Pair