BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Platelet-activating factor receptor' and Ligand = 'BDBM50001747'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Sante Curated by PDSP K_i Database									J Pharmacol Exp Ther 252: 1221-7 (1990) BindingDB Entry DOI: 10.7270/Q2JW8CC2
Rhone-Poulenc Sante Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Sante Curated by PDSP K_i Database									J Pharmacol Exp Ther 252: 1221-7 (1990) BindingDB Entry DOI: 10.7270/Q2JW8CC2
Rhone-Poulenc Sante Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50% of the specific [3H]PAF binding, obtained as natural product.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50% of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit PAF binding to rabbit platelet membrane				Bioorg Med Chem Lett 1: 327-332 (1991) Article DOI: 10.1016/S0960-894X(01)80818-0 BindingDB Entry DOI: 10.7270/Q2TM7BKP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition concentration required to block 50% of the specific [3H]PAF binding, obtained from Chiralpak column at low temperatures.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitor concentration required to block 50 %of the specific [3H]PAF binding to rabbit platelet membranes.				J Med Chem 30: 136-42 (1987) BindingDB Entry DOI: 10.7270/Q25T3M2X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50001747 ((+)-Kadsurenone \| (Kadsurenone)5-Allyl-2-(3,4-dime...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
American Cyanamid Company Curated by ChEMBL					Assay Description Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma				J Med Chem 36: 580-90 (1993) BindingDB Entry DOI: 10.7270/Q2SX6C9X
American Cyanamid Company Curated by ChEMBL					More data for this Ligand-Target Pair