BindingDB PrimarySearch

Found 12 hits with Last Name = 'kasahara' and Initial = 'c'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human MAPK p38alpha by Z'-LYTE assay				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human MAPK p38beta by Z'-LYTE assay				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant JNK2alpha2-mediated ATF-2 phosphorylation after 30 mins by immunoblotting method				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2C9				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390211 (CHEMBL2070134) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by Rb efflux assay				Bioorg Med Chem Lett 22: 5681-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.087 BindingDB Entry DOI: 10.7270/Q25X2B0C
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390210 (CHEMBL2070133) Show SMILES COc1cnc(nc1NCc1c(F)cc(F)cc1F)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by Rb efflux assay				Bioorg Med Chem Lett 22: 5681-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.087 BindingDB Entry DOI: 10.7270/Q25X2B0C
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50390209 (CHEMBL2070131) Show SMILES COc1cnc(nc1NCc1ccccc1F)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by Rb efflux assay				Bioorg Med Chem Lett 22: 5681-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.087 BindingDB Entry DOI: 10.7270/Q25X2B0C
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2D6				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2C19				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of CYP1A2				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 using midazolam as substrate				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50396845 (CHEMBL2170294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by Rb ion flux assay				J Med Chem 55: 7772-85 (2012) Article DOI: 10.1021/jm3008008 BindingDB Entry DOI: 10.7270/Q2QN67XZ
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair