Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lanosterol synthase (Rattus norvegicus) | BDBM50051375 ((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Binding affinity towards competitive inhibition against rat microsomal Oxidosqualene-lanosterol cyclase | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051375 ((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Binding affinity towards noncompetetive inhibition against rat microsomal Oxidosqualene-lanosterol cyclase | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051383 ((4aR,6S,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051372 ((6R,8aR)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051375 ((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051372 ((6R,8aR)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051371 (1,1,4a-Trimethyl-5-(4,8,12-trimethyl-trideca-3,7,1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051366 ((E)-1-((6S,8aS)-6-Hydroxy-5,5,8a-trimethyl-3,5,6,7...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051380 ((4aS,6S,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051376 ((4aR,6S,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051368 ((6S,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051373 ((6S,8aS)-2-Dodecyl-5,5,8a-trimethyl-1,2,3,5,6,7,8,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051379 ((6S,8aS)-5,5,8a-Trimethyl-2-tetradecyl-1,2,3,5,6,7...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051370 ((6S,8aS)-5,5,8a-Trimethyl-2-((Z)-1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051382 ((6S,8aS)-2-Dodecyl-8a-methyl-1,2,3,5,6,7,8,8a-octa...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051367 ((6S,8aS)-2-(1,5-Dimethyl-hex-4-enyl)-5,5,8a-trimet...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051381 ((6R,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051378 ((6S,8aS)-2-Benzyl-5,5,8a-trimethyl-1,2,3,5,6,7,8,8...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051365 ((6S,8aS)-5,5,8a-Trimethyl-2-(3-phenyl-propyl)-1,2,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003030 ((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051377 ((4aR,8aS)-2-Dodecyl-5,5-dimethyl-decahydro-isoquin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051374 ((6S,8aS)-5,5,8a-Trimethyl-1,2,3,5,6,7,8,8a-octahyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50051369 ((6S,8aS)-5,5,8a-Trimethyl-2-octadecyl-1,2,3,5,6,7,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes | J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB | |||||||||||
More data for this Ligand-Target Pair |