Compile Data Set for Download or QSAR

Found 127 hits with Last Name = 'pelekoudas' and Initial = 'dn'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538919 (CHEMBL4633233) Show SMILES COc1ccc(cc1F)-c1ccc(COC2(CN(C2)C#N)C2CC2)c(F)c1 Show InChI InChI=1S/C21H20F2N2O2/c1-26-20-7-4-15(9-19(20)23)14-2-3-16(18(22)8-14)10-27-21(17-5-6-17)11-25(12-21)13-24/h2-4,7-9,17H,5-6,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM393394 (US9963444, Example 95) Show SMILES COc1cccc(c1)-c1ccc(COC2(C)CN(C2)C#N)cc1 Show InChI InChI=1S/C19H20N2O2/c1-19(12-21(13-19)14-20)23-11-15-6-8-16(9-7-15)17-4-3-5-18(10-17)22-2/h3-10H,11-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393375 (3-((4'-Methyl-[1,1'-biphenyl]-4-yl)methoxy)azetidi...) Show SMILES Cc1ccc(cc1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C18H18N2O/c1-14-2-6-16(7-3-14)17-8-4-15(5-9-17)12-21-18-10-20(11-18)13-19/h2-9,18H,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393377 (3-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)metho...) Show SMILES COc1cccc(c1)-c1ccc(COC2CN(C2)C#N)c(F)c1 Show InChI InChI=1S/C18H17FN2O2/c1-22-16-4-2-3-13(7-16)14-5-6-15(18(19)8-14)11-23-17-9-21(10-17)12-20/h2-8,17H,9-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393376 (3-((4'-Fluoro-[1,1'-biphenyl]-4-yl)methoxy)azetidi...) Show SMILES Fc1ccc(cc1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C17H15FN2O/c18-16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-21-17-9-20(10-17)12-19/h1-8,17H,9-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393378 (3-((3'-Methoxy-3-(trifluoromethyl)-[1,1'-biphenyl]...) Show SMILES COc1cccc(c1)-c1ccc(COC2CN(C2)C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C19H17F3N2O2/c1-25-16-4-2-3-13(7-16)14-5-6-15(18(8-14)19(20,21)22)11-26-17-9-24(10-17)12-23/h2-8,17H,9-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393368 (3-((2',3'-Dimethoxy-[1,1'-biphenyl]-4-yl)methoxy)a...) Show SMILES COc1cccc(-c2ccc(COC3CN(C3)C#N)cc2)c1OC Show InChI InChI=1S/C19H20N2O3/c1-22-18-5-3-4-17(19(18)23-2)15-8-6-14(7-9-15)12-24-16-10-21(11-16)13-20/h3-9,16H,10-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.880	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393366 (3-((3'-Methoxy-[1,1'-biphenyl]-4-yl)methoxy)azetid...) Show SMILES COc1cccc(c1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C18H18N2O2/c1-21-17-4-2-3-16(9-17)15-7-5-14(6-8-15)12-22-18-10-20(11-18)13-19/h2-9,18H,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393366 (3-((3'-Methoxy-[1,1'-biphenyl]-4-yl)methoxy)azetid...) Show SMILES COc1cccc(c1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C18H18N2O2/c1-21-17-4-2-3-16(9-17)15-7-5-14(6-8-15)12-22-18-10-20(11-18)13-19/h2-9,18H,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393362 (US9963444, Example 63) Show SMILES COc1ccc(cc1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C18H18N2O2/c1-21-17-8-6-16(7-9-17)15-4-2-14(3-5-15)12-22-18-10-20(11-18)13-19/h2-9,18H,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538909 (CHEMBL4637701) Show SMILES Brc1cc(Oc2ccccc2)ccc1COC1CN(C1)C#N Show InChI InChI=1S/C17H15BrN2O2/c18-17-8-15(22-14-4-2-1-3-5-14)7-6-13(17)11-21-16-9-20(10-16)12-19/h1-8,16H,9-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50538919 (CHEMBL4633233) Show SMILES COc1ccc(cc1F)-c1ccc(COC2(CN(C2)C#N)C2CC2)c(F)c1 Show InChI InChI=1S/C21H20F2N2O2/c1-26-20-7-4-15(9-19(20)23)14-2-3-16(18(22)8-14)10-27-21(17-5-6-17)11-25(12-21)13-24/h2-4,7-9,17H,5-6,10-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393380 (3-((4-Phenoxybenzyl)oxy)azetidine-1-carbonitrile |...) Show SMILES N#CN1CC(C1)OCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O2/c18-13-19-10-17(11-19)20-12-14-6-8-16(9-7-14)21-15-4-2-1-3-5-15/h1-9,17H,10-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393384 (US9963444, Example 85) Show SMILES N#CN1CC(C1)OCc1ccc(cc1)-c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C24H22N2O2/c25-18-26-14-24(15-26)28-17-20-9-11-21(12-10-20)22-7-4-8-23(13-22)27-16-19-5-2-1-3-6-19/h1-13,24H,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538916 (CHEMBL4646586) Show SMILES FC(F)(F)c1ccc(cc1)-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C18H15F3N2O/c19-18(20,21)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-24-17-9-23(10-17)12-22/h1-8,17H,9-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538910 (CHEMBL4645560) Show SMILES COc1ccc(cc1F)-c1ccc2CN(Cc2c1)C1CN(C1)C#N Show InChI InChI=1S/C19H18FN3O/c1-24-19-5-4-14(7-18(19)20)13-2-3-15-8-23(9-16(15)6-13)17-10-22(11-17)12-21/h2-7,17H,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538911 (CHEMBL4635238) Show SMILES COc1cccc(c1)-c1ccc(cc1)C(=O)NC1(C)CN(C1)C#N Show InChI InChI=1S/C19H19N3O2/c1-19(11-22(12-19)13-20)21-18(23)15-8-6-14(7-9-15)16-4-3-5-17(10-16)24-2/h3-10H,11-12H2,1-2H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393394 (US9963444, Example 95) Show SMILES COc1cccc(c1)-c1ccc(COC2(C)CN(C2)C#N)cc1 Show InChI InChI=1S/C19H20N2O2/c1-19(12-21(13-19)14-20)23-11-15-6-8-16(9-7-15)17-4-3-5-18(10-17)22-2/h3-10H,11-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50538918 (CHEMBL4638402) Show SMILES COc1ccc(cc1F)-c1ccc(COC2(CN(C2)C#N)c2cccnc2)c(F)c1 Show InChI InChI=1S/C23H19F2N3O2/c1-29-22-7-6-17(10-21(22)25)16-4-5-18(20(24)9-16)12-30-23(13-28(14-23)15-26)19-3-2-8-27-11-19/h2-11H,12-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM447488 (US10689357, Example 25) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H]1C[C@H](C1)N=C=S |r,wU:18.19,20.24,(-9.61,-3.62,;-8.28,-4.39,;-6.94,-3.62,;-6.94,-2.08,;-5.61,-1.31,;-4.28,-2.08,;-4.28,-3.62,;-5.61,-4.39,;-2.94,-1.31,;-2.94,.23,;-1.61,1,;-.28,.23,;-.28,-1.31,;-1.61,-2.08,;1.06,1,;.29,2.33,;1.83,2.33,;2.39,.23,;3.72,1,;4.12,2.48,;5.61,2.08,;5.21,.6,;6.94,2.85,;8.28,3.62,;9.61,4.39,)| Show InChI InChI=1S/C18H18N2O3S2/c1-23-17-6-2-13(3-7-17)14-4-8-18(9-5-14)25(21,22)20-16-10-15(11-16)19-12-24/h2-9,15-16,20H,10-11H2,1H3/t15-,16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393391 (3-((4'-Cyano-5-phenoxy-[1,1'-biphenyl]-2-yl)methox...) Show SMILES N#CN1CC(C1)OCc1ccc(Oc2ccccc2)cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C24H19N3O2/c25-13-18-6-8-19(9-7-18)24-12-22(29-21-4-2-1-3-5-21)11-10-20(24)16-28-23-14-27(15-23)17-26/h1-12,23H,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393379 (3-((3,3'-Dimethoxy-[1,1'-biphenyl]-4-yl)methoxy)az...) Show SMILES COc1cccc(c1)-c1ccc(COC2CN(C2)C#N)c(OC)c1 Show InChI InChI=1S/C19H20N2O3/c1-22-17-5-3-4-14(8-17)15-6-7-16(19(9-15)23-2)12-24-18-10-21(11-18)13-20/h3-9,18H,10-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393363 (3-([1,1'-Biphenyl]-4-ylmethoxy)azetidine-1-carboni...) Show SMILES N#CN1CC(C1)OCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H16N2O/c18-13-19-10-17(11-19)20-12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,17H,10-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538914 (CHEMBL4637755) Show SMILES COc1cccc(c1)-c1ccc(cc1)S(=O)(=O)N1CCC11CN(C1)C#N Show InChI InChI=1S/C19H19N3O3S/c1-25-17-4-2-3-16(11-17)15-5-7-18(8-6-15)26(23,24)22-10-9-19(22)12-21(13-19)14-20/h2-8,11H,9-10,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393363 (3-([1,1'-Biphenyl]-4-ylmethoxy)azetidine-1-carboni...) Show SMILES N#CN1CC(C1)OCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H16N2O/c18-13-19-10-17(11-19)20-12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,17H,10-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538912 (CHEMBL4643588) Show SMILES COc1cccc(c1)-c1ccc(cc1)S(=O)(=O)NC1(C)CN(C1)C#N Show InChI InChI=1S/C18H19N3O3S/c1-18(11-21(12-18)13-19)20-25(22,23)17-8-6-14(7-9-17)15-4-3-5-16(10-15)24-2/h3-10,20H,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM447493 (US10689357, Example 30) Show SMILES COc1ccc(cc1F)-c1ccc(cc1)S(=O)(=O)N[C@H]1C[C@H](C1)N=C=S |r,wU:19.20,21.25,(-11.93,2.49,;-11.4,1.04,;-9.86,1.04,;-9.09,2.37,;-7.55,2.37,;-6.78,1.04,;-7.55,-.3,;-9.09,-.3,;-9.86,-1.63,;-5.24,1.04,;-4.47,-.3,;-2.93,-.3,;-2.16,1.04,;-2.93,2.37,;-4.47,2.37,;-.62,1.04,;-.62,-.5,;-.62,2.58,;.92,1.04,;2.46,1.04,;3.54,2.13,;5.14,1.04,;3.54,-.05,;7.03,1.04,;7.98,2.68,;8.93,4.32,)| Show InChI InChI=1S/C18H17FN2O3S2/c1-24-18-7-4-13(8-17(18)19)12-2-5-16(6-3-12)26(22,23)21-15-9-14(10-15)20-11-25/h2-8,14-15,21H,9-10H2,1H3/t14-,15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393385 (US9963444, Example 86) Show SMILES N#CN1CC(COCc2ccc(cc2)-c2ccccc2)C1 Show InChI InChI=1S/C18H18N2O/c19-14-20-10-16(11-20)13-21-12-15-6-8-18(9-7-15)17-4-2-1-3-5-17/h1-9,16H,10-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50576137 (CHEMBL4863412) Show SMILES Fc1cc(ccc1CO[C@H]1C[C@H](C1)N=C=S)-c1ccc2OCCc2c1 |r,wU:9.9,11.14,(13.46,-17.55,;12.7,-18.88,;11.16,-18.9,;10.4,-20.24,;11.19,-21.57,;12.73,-21.55,;13.49,-20.22,;15.02,-20.2,;15.81,-21.53,;17.35,-21.52,;18.42,-20.42,;19.52,-21.5,;18.44,-22.59,;21.06,-21.48,;21.84,-22.81,;22.6,-24.13,;8.86,-20.26,;8.09,-18.93,;6.55,-18.94,;5.78,-20.28,;4.27,-20.63,;4.13,-22.17,;5.56,-22.78,;6.58,-21.61,;8.12,-21.59,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538918 (CHEMBL4638402) Show SMILES COc1ccc(cc1F)-c1ccc(COC2(CN(C2)C#N)c2cccnc2)c(F)c1 Show InChI InChI=1S/C23H19F2N3O2/c1-29-22-7-6-17(10-21(22)25)16-4-5-18(20(24)9-16)12-30-23(13-28(14-23)15-26)19-3-2-8-27-11-19/h2-11H,12-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393389 (3-((4'-Methoxy-5-phenoxy-[1,1'-biphenyl]-2-yl)meth...) Show SMILES COc1ccc(cc1)-c1cc(Oc2ccccc2)ccc1COC1CN(C1)C#N Show InChI InChI=1S/C24H22N2O3/c1-27-20-10-7-18(8-11-20)24-13-22(29-21-5-3-2-4-6-21)12-9-19(24)16-28-23-14-26(15-23)17-25/h2-13,23H,14-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393373 (3-((4-(2-Methoxypyridin-3-yl)benzyl)oxy)azetidine-...) Show SMILES COc1ncccc1-c1ccc(COC2CN(C2)C#N)cc1 Show InChI InChI=1S/C17H17N3O2/c1-21-17-16(3-2-8-19-17)14-6-4-13(5-7-14)11-22-15-9-20(10-15)12-18/h2-8,15H,9-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538922 (CHEMBL4647961) Show SMILES C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C22H32N2O5S/c1-16-20(21(25)24(16)18-12-8-13-19(15-18)30(2,27)28)23-22(26)29-14-7-6-11-17-9-4-3-5-10-17/h8,12-13,15-17,20H,3-7,9-11,14H2,1-2H3,(H,23,26)/t16-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538922 (CHEMBL4647961) Show SMILES C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C22H32N2O5S/c1-16-20(21(25)24(16)18-12-8-13-19(15-18)30(2,27)28)23-22(26)29-14-7-6-11-17-9-4-3-5-10-17/h8,12-13,15-17,20H,3-7,9-11,14H2,1-2H3,(H,23,26)/t16-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of NAAA (unknown origin)				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393397 (3-((4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)benzyl)...) Show SMILES N#CN1CC(C1)(OCc1ccc(cc1)-c1ccc2OCCOc2c1)c1ccccc1 Show InChI InChI=1S/C25H22N2O3/c26-18-27-16-25(17-27,22-4-2-1-3-5-22)30-15-19-6-8-20(9-7-19)21-10-11-23-24(14-21)29-13-12-28-23/h1-11,14H,12-13,15-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM447489 (US10689357, Example 26) Show SMILES COc1ccc(cc1)-c1ccc(nc1)S(=O)(=O)N[C@H]1C[C@H](C1)N=C=S |r,wU:18.19,20.24,(-9.61,-3.62,;-8.28,-4.39,;-6.94,-3.62,;-6.94,-2.08,;-5.61,-1.31,;-4.28,-2.08,;-4.28,-3.62,;-5.61,-4.39,;-2.94,-1.31,;-2.94,.23,;-1.61,1,;-.28,.23,;-.28,-1.31,;-1.61,-2.08,;1.06,1,;.29,2.33,;1.83,2.33,;2.39,.23,;3.72,1,;4.12,2.48,;5.61,2.08,;5.21,.6,;6.94,2.85,;8.28,3.62,;9.61,4.39,)| Show InChI InChI=1S/C17H17N3O3S2/c1-23-16-5-2-12(3-6-16)13-4-7-17(18-10-13)25(21,22)20-15-8-14(9-15)19-11-24/h2-7,10,14-15,20H,8-9H2,1H3/t14-,15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50538913 (CHEMBL4649749) Show SMILES COc1cccc(c1)-c1ccc(cc1)C(=O)N1CCC11CN(C1)C#N Show InChI InChI=1S/C20H19N3O2/c1-25-18-4-2-3-17(11-18)15-5-7-16(8-6-15)19(24)23-10-9-20(23)12-22(13-20)14-21/h2-8,11H,9-10,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393392 (3-((2'-Cyano-5-phenoxy-[1,1'-biphenyl]-2-yl)methox...) Show SMILES N#CN1CC(C1)OCc1ccc(Oc2ccccc2)cc1-c1ccccc1C#N Show InChI InChI=1S/C24H19N3O2/c25-13-18-6-4-5-9-23(18)24-12-21(29-20-7-2-1-3-8-20)11-10-19(24)16-28-22-14-27(15-22)17-26/h1-12,22H,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50439664 (CHEMBL2419814 | US9353075, 17) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C18H17NO4/c1-12-16(17(20)23-12)19-18(21)22-11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10,12,16H,11H2,1H3,(H,19,21)/t12-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50389023 (CHEMBL2064166 | US9353075, 6) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 |r| Show InChI InChI=1S/C16H21NO4/c1-12-14(15(18)21-12)17-16(19)20-11-7-3-6-10-13-8-4-2-5-9-13/h2,4-5,8-9,12,14H,3,6-7,10-11H2,1H3,(H,17,19)/t12-,14+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM447497 (US10689357, Example 33) Show SMILES COc1ccc(cc1)-c1ccc(OC(=O)N[C@H]2C[C@H](C2)N=C=S)cc1 |r,wU:16.16,18.21,(-10.53,-1.93,;-9.2,-2.7,;-7.86,-1.93,;-7.86,-.39,;-6.53,.39,;-5.2,-.39,;-5.2,-1.93,;-6.53,-2.7,;-3.86,.39,;-3.86,1.93,;-2.53,2.7,;-1.19,1.93,;.14,2.7,;1.47,1.93,;1.47,.39,;2.81,2.7,;4.64,1.93,;6.13,2.32,;6.53,.84,;5.04,.44,;7.86,.07,;9.2,-.7,;10.53,-1.47,;-1.19,.39,;-2.53,-.39,)| Show InChI InChI=1S/C19H18N2O3S/c1-23-17-6-2-13(3-7-17)14-4-8-18(9-5-14)24-19(22)21-16-10-15(11-16)20-12-25/h2-9,15-16H,10-11H2,1H3,(H,21,22)/t15-,16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM447480 (US10689357, Example 18) Show SMILES COc1ccc(cc1)-c1ccc(nc1)C(=O)N[C@H]1C[C@H](C1)N=C=S |r,wU:17.18,19.23,(-9.61,-3.62,;-8.28,-4.39,;-6.94,-3.62,;-6.94,-2.08,;-5.61,-1.31,;-4.28,-2.08,;-4.28,-3.62,;-5.61,-4.39,;-2.94,-1.31,;-2.94,.23,;-1.61,1,;-.28,.23,;-.28,-1.31,;-1.61,-2.08,;1.06,1,;1.06,2.54,;2.39,.23,;3.72,1,;4.12,2.48,;5.61,2.08,;5.21,.6,;6.94,2.85,;8.28,3.62,;9.61,4.39,)| Show InChI InChI=1S/C18H17N3O2S/c1-23-16-5-2-12(3-6-16)13-4-7-17(19-10-13)18(22)21-15-8-14(9-15)20-11-24/h2-7,10,14-15H,8-9H2,1H3,(H,21,22)/t14-,15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50576160 (CHEMBL4863536) Show SMILES S=C=NC1CN(CCCCCCc2ccccc2)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50576139 (CHEMBL4854759) Show SMILES S=C=N[C@@H]1C[C@@H](C1)OCc1ccc(cn1)-c1ccc2occc2c1 |r,wU:5.7,3.2,(22.54,-38.89,;21.78,-37.56,;21,-36.24,;19.46,-36.25,;18.36,-35.17,;17.28,-36.27,;18.38,-37.35,;15.74,-36.28,;14.96,-34.96,;13.42,-34.97,;12.64,-33.64,;11.1,-33.65,;10.34,-34.99,;11.13,-36.33,;12.67,-36.31,;8.8,-35.01,;8.02,-33.68,;6.49,-33.7,;5.72,-35.03,;4.21,-35.38,;4.07,-36.92,;5.5,-37.53,;6.52,-36.36,;8.06,-36.35,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393386 (US9963444, Example 87) Show SMILES N#CN1CC(C1)OCc1ccc(Oc2ccccc2)cc1-c1ccccc1 Show InChI InChI=1S/C23H20N2O2/c24-17-25-14-22(15-25)26-16-19-11-12-21(27-20-9-5-2-6-10-20)13-23(19)18-7-3-1-4-8-18/h1-13,22H,14-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393336 (5-(3-Fluoro-4-(((1S,3S)-3-isothiocyanatocyclobutox...) Show SMILES Fc1cc(ccc1CO[C@H]1C[C@H](C1)N=C=S)-c1ccc2OCOc2c1 |r,wU:9.9,11.14,(-2.37,3.37,;-2.37,1.83,;-3.7,1.06,;-3.7,-.48,;-2.37,-1.25,;-1.04,-.48,;-1.04,1.06,;.3,1.83,;1.63,1.06,;2.96,1.83,;3.36,3.32,;4.85,2.92,;4.45,1.43,;6.18,3.69,;7.52,4.46,;8.85,5.23,;-5.04,-1.25,;-6.37,-.48,;-7.71,-1.25,;-7.71,-2.79,;-8.85,-3.82,;-8.22,-5.23,;-6.69,-5.07,;-6.37,-3.56,;-5.04,-2.79,)| Show InChI InChI=1S/C19H16FNO3S/c20-17-5-12(13-3-4-18-19(6-13)24-11-23-18)1-2-14(17)9-22-16-7-15(8-16)21-10-25/h1-6,15-16H,7-9,11H2/t15-,16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM319796 (US10174015, Compound 9) Show SMILES Clc1cccc(CCCCCC(=O)N2CCOC2=O)c1 Show InChI InChI=1S/C15H18ClNO3/c16-13-7-4-6-12(11-13)5-2-1-3-8-14(18)17-9-10-20-15(17)19/h4,6-7,11H,1-3,5,8-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAAA (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00076 BindingDB Entry DOI: 10.7270/Q2C25175
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM319796 (US10174015, Compound 9) Show SMILES Clc1cccc(CCCCCC(=O)N2CCOC2=O)c1 Show InChI InChI=1S/C15H18ClNO3/c16-13-7-4-6-12(11-13)5-2-1-3-8-14(18)17-9-10-20-15(17)19/h4,6-7,11H,1-3,5,8-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of rat NAAA				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393395 (3-((3'-Methoxy-[1,1'-biphenyl]-4-yl)methoxy)-3-phe...) Show SMILES COc1cccc(c1)-c1ccc(COC2(CN(C2)C#N)c2ccccc2)cc1 Show InChI InChI=1S/C24H22N2O2/c1-27-23-9-5-6-21(14-23)20-12-10-19(11-13-20)15-28-24(16-26(17-24)18-25)22-7-3-2-4-8-22/h2-14H,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM393396 (3-((4-(Benzo[d][1,3]dioxol-5-yl)benzyl)oxy)-3-phen...) Show SMILES N#CN1CC(C1)(OCc1ccc(cc1)-c1ccc2OCOc2c1)c1ccccc1 Show InChI InChI=1S/C24H20N2O3/c25-16-26-14-24(15-26,21-4-2-1-3-5-21)29-13-18-6-8-19(9-7-18)20-10-11-22-23(12-20)28-17-27-22/h1-12H,13-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assay				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115195 BindingDB Entry DOI: 10.7270/Q2K35Z63
					More data for this Ligand-Target Pair

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