Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM14774![]() (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50427452![]() (CHEMBL2326941) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50427452![]() (CHEMBL2326941) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50453147![]() (CHEMBL4202704) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453158![]() (CHEMBL4210475) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453158![]() (CHEMBL4210475) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453161![]() (CHEMBL4204999) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain (565 to 918 residues) expressed in Escherichia coli BL21 incubated for 20 mins using cAMP as ... | Bioorg Med Chem 27: 3998-4012 (2019) Article DOI: 10.1016/j.bmc.2019.06.027 BindingDB Entry DOI: 10.7270/Q23N26QR | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453158![]() (CHEMBL4210475) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain (565 to 918 residues) expressed in Escherichia coli BL21 incubated for 20 mins using cAMP as ... | Bioorg Med Chem 27: 3998-4012 (2019) Article DOI: 10.1016/j.bmc.2019.06.027 BindingDB Entry DOI: 10.7270/Q23N26QR | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512768![]() (CHEMBL4454951) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512761![]() (CHEMBL4445930) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453161![]() (CHEMBL4204999) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512763![]() (CHEMBL4439778) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512772![]() (CHEMBL4444414) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512770![]() (CHEMBL4521383) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50453171![]() (CHEMBL4202975) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453171![]() (CHEMBL4202975) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512766![]() (CHEMBL4436770) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512750![]() (CHEMBL4439032) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512752![]() (CHEMBL4445489) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512750![]() (CHEMBL4439032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453180![]() (CHEMBL4208363) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512773![]() (CHEMBL4453045) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512759![]() (CHEMBL4516631) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512752![]() (CHEMBL4445489) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453173![]() (CHEMBL4218658) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512762![]() (CHEMBL4443772) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512751![]() (CHEMBL4522881) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512753![]() (CHEMBL4463356) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512592![]() (CHEMBL4465919) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain incubated for 20 mins using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 3998-4012 (2019) Article DOI: 10.1016/j.bmc.2019.06.027 BindingDB Entry DOI: 10.7270/Q23N26QR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453170![]() (CHEMBL4214364) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512771![]() (CHEMBL4565967) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512758![]() (CHEMBL4566533) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512592![]() (CHEMBL4465919) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512767![]() (CHEMBL4473629) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512764![]() (CHEMBL4439798) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512759![]() (CHEMBL4516631) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512769![]() (CHEMBL4453613) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453176![]() (CHEMBL4217833) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512604![]() (CHEMBL4464777) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain incubated for 20 mins using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 3998-4012 (2019) Article DOI: 10.1016/j.bmc.2019.06.027 BindingDB Entry DOI: 10.7270/Q23N26QR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512601![]() (CHEMBL4519708) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain (565 to 918 residues) expressed in Escherichia coli BL21 incubated for 20 mins using cAMP as ... | Bioorg Med Chem 27: 3998-4012 (2019) Article DOI: 10.1016/j.bmc.2019.06.027 BindingDB Entry DOI: 10.7270/Q23N26QR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512771![]() (CHEMBL4565967) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50512772![]() (CHEMBL4444414) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of human PDE4B catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512760![]() (CHEMBL4435831) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453175![]() (CHEMBL4204966) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453177![]() (CHEMBL4206114) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50512765![]() (CHEMBL4583339) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei PDEB1 catalytic domain using cAMP as substrate incubated for 20 mins by PDELight HTS cAMP phosphodiesterase Kit base... | Bioorg Med Chem 27: 4013-4029 (2019) Article DOI: 10.1016/j.bmc.2019.06.026 BindingDB Entry DOI: 10.7270/Q2Z03CHQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453147![]() (CHEMBL4202704) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453166![]() (CHEMBL4213296) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453160![]() (CHEMBL4209841) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase (Trypanosoma brucei) | BDBM50453168![]() (CHEMBL4209331) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam Curated by ChEMBL | Assay Description Inhibition of full length Trypanosoma brucei PDEB1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assay | J Med Chem 61: 3870-3888 (2018) Article DOI: 10.1021/acs.jmedchem.7b01670 BindingDB Entry DOI: 10.7270/Q2P84FF9 | |||||||||||
More data for this Ligand-Target Pair |
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