Compile Data Set for Download or QSAR

Found 20 hits with Last Name = 'silva' and Initial = 'er'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50241867 (((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...) Show SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de S£o Carlos Curated by ChEMBL					Assay Description Competitive inhibition of Leishmania amazonensis arginase assessed as inhibition constant for enzyme-inhibitor complex using L-arginine as substrate ...				J Nat Prod 79: 1459-63 (2016) Article DOI: 10.1021/acs.jnatprod.5b00875 BindingDB Entry DOI: 10.7270/Q2G73J78
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521944 (CHEMBL4204512) Show SMILES CC(=O)Nc1ccc(C)cc1C(F)(F)C(=O)NNc1ccccc1 Show InChI InChI=1S/C17H17F2N3O2/c1-11-8-9-15(20-12(2)23)14(10-11)17(18,19)16(24)22-21-13-6-4-3-5-7-13/h3-10,21H,1-2H3,(H,20,23)(H,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521942 (CHEMBL4216180) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccccc1 Show InChI InChI=1S/C16H15F2N3O2/c1-11(22)19-14-10-6-5-9-13(14)16(17,18)15(23)21-20-12-7-3-2-4-8-12/h2-10,20H,1H3,(H,19,22)(H,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 mins				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521943 (CHEMBL4574177) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H14F5N3O2/c1-10(26)23-14-5-3-2-4-13(14)16(18,19)15(27)25-24-12-8-6-11(7-9-12)17(20,21)22/h2-9,24H,1H3,(H,23,26)(H,25,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521947 (CHEMBL4530523) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H16F2N2O2/c1-12(22)21-15-10-6-5-9-14(15)17(18,19)16(23)20-11-13-7-3-2-4-8-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510709 (CHEMBL4571367) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C12H11N7S/c13-12(20)18-17-10-9-6-16-19(11(9)15-7-14-10)8-4-2-1-3-5-8/h1-7H,(H3,13,18,20)(H,14,15,17)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521942 (CHEMBL4216180) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccccc1 Show InChI InChI=1S/C16H15F2N3O2/c1-11(22)19-14-10-6-5-9-13(14)16(17,18)15(23)21-20-12-7-3-2-4-8-12/h2-10,20H,1H3,(H,19,22)(H,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521944 (CHEMBL4204512) Show SMILES CC(=O)Nc1ccc(C)cc1C(F)(F)C(=O)NNc1ccccc1 Show InChI InChI=1S/C17H17F2N3O2/c1-11-8-9-15(20-12(2)23)14(10-11)17(18,19)16(24)22-21-13-6-4-3-5-7-13/h3-10,21H,1-2H3,(H,20,23)(H,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 mins				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521947 (CHEMBL4530523) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H16F2N2O2/c1-12(22)21-15-10-6-5-9-14(15)17(18,19)16(23)20-11-13-7-3-2-4-8-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521943 (CHEMBL4574177) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H14F5N3O2/c1-10(26)23-14-5-3-2-4-13(14)16(18,19)15(27)25-24-12-8-6-11(7-9-12)17(20,21)22/h2-9,24H,1H3,(H,23,26)(H,25,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510711 (CHEMBL4467463) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10F3N7S/c14-13(15,16)7-1-3-8(4-2-7)23-11-9(5-20-23)10(18-6-19-11)21-22-12(17)24/h1-6H,(H3,17,22,24)(H,18,19,21)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510712 (CHEMBL4570250) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C12H10ClN7S/c13-7-1-3-8(4-2-7)20-11-9(5-17-20)10(15-6-16-11)18-19-12(14)21/h1-6H,(H3,14,19,21)(H,15,16,18)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521945 (CHEMBL4216693) Show SMILES CC(=O)Nc1ccc(C)cc1C(F)(F)C(=O)NNc1ccccn1 Show InChI InChI=1S/C16H16F2N4O2/c1-10-6-7-13(20-11(2)23)12(9-10)16(17,18)15(24)22-21-14-5-3-4-8-19-14/h3-9H,1-2H3,(H,19,21)(H,20,23)(H,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510707 (CHEMBL4541649) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C13H10N8S/c14-5-8-1-3-9(4-2-8)21-12-10(6-18-21)11(16-7-17-12)19-20-13(15)22/h1-4,6-7H,(H3,15,20,22)(H,16,17,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510708 (CHEMBL4456185) Show SMILES Cc1ccc(cc1)-n1ncc2c(NNC(N)=S)ncnc12 Show InChI InChI=1S/C13H13N7S/c1-8-2-4-9(5-3-8)20-12-10(6-17-20)11(15-7-16-12)18-19-13(14)21/h2-7H,1H3,(H3,14,19,21)(H,15,16,18)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510710 (CHEMBL4438412) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(F)cc1 Show InChI InChI=1S/C12H10FN7S/c13-7-1-3-8(4-2-7)20-11-9(5-17-20)10(15-6-16-11)18-19-12(14)21/h1-6H,(H3,14,19,21)(H,15,16,18)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026 BindingDB Entry DOI: 10.7270/Q2SX6HJQ
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50521946 (CHEMBL4211729) Show SMILES CC(=O)Nc1ccccc1C(F)(F)C(=O)NNc1ccccn1 Show InChI InChI=1S/C15H14F2N4O2/c1-10(22)19-12-7-3-2-6-11(12)15(16,17)14(23)21-20-13-8-4-5-9-18-13/h2-9H,1H3,(H,18,20)(H,19,22)(H,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production using L-arginine as ...				Bioorg Med Chem 27: 3853-3859 (2019) Article DOI: 10.1016/j.bmc.2019.07.022 BindingDB Entry DOI: 10.7270/Q27D2ZJF
					More data for this Ligand-Target Pair