Found 121 hits with Last Name = 'lowe' and Initial = 'ew' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peptidylglycine alpha-amidating monooxygenase
(Rattus norvegicus) | BDBM50273316
(CHEMBL509495 | N-dansyl-Tyr-Val-D-Ala)Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)N[C@H](C)C(O)=O |r| Show InChI InChI=1S/C29H36N4O7S/c1-17(2)26(28(36)30-18(3)29(37)38)31-27(35)23(16-19-12-14-20(34)15-13-19)32-41(39,40)25-11-7-8-21-22(25)9-6-10-24(21)33(4)5/h6-15,17-18,23,26,32,34H,16H2,1-5H3,(H,30,36)(H,31,35)(H,37,38)/t18-,23+,26+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Florida
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidation |
Bioorg Med Chem 16: 10061-74 (2008)
Article DOI: 10.1016/j.bmc.2008.10.013 BindingDB Entry DOI: 10.7270/Q22R3RHS |
More data for this Ligand-Target Pair | |
Peptidylglycine alpha-amidating monooxygenase
(Rattus norvegicus) | BDBM50273962
(CHEMBL445286 | Phenylthioacetylglycine)Show InChI InChI=1S/C10H11NO2S/c12-10(13)7-11-9(14)6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.80E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Florida
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidation |
Bioorg Med Chem 16: 10061-74 (2008)
Article DOI: 10.1016/j.bmc.2008.10.013 BindingDB Entry DOI: 10.7270/Q22R3RHS |
More data for this Ligand-Target Pair | |
Peptidylglycine alpha-amidating monooxygenase
(Rattus norvegicus) | BDBM50273494
(6-O-Palmitoyl-L-ascorbate | CHEMBL457018)Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@@H]1OC(=O)C(O)C1O |r| Show InChI InChI=1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,19-21,23,25-26H,2-16H2,1H3/t17-,19?,20?,21-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Florida
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase in presence of DMSO |
Bioorg Med Chem 16: 10061-74 (2008)
Article DOI: 10.1016/j.bmc.2008.10.013 BindingDB Entry DOI: 10.7270/Q22R3RHS |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416888
(CHEMBL1257363)Show SMILES CCC(=O)Oc1ccc(cc1)[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(=O)CC |r| Show InChI InChI=1S/C23H22N4O4S/c1-4-18(28)27-17-9-7-6-8-16(17)20-21(24-23(32-3)26-25-20)31-22(27)14-10-12-15(13-11-14)30-19(29)5-2/h6-13,22H,4-5H2,1-3H3/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416889
(CHEMBL1258290)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccccc1C |r| Show InChI InChI=1S/C21H20N4O2S/c1-4-17(26)25-16-12-8-7-11-15(16)18-19(22-21(28-3)24-23-18)27-20(25)14-10-6-5-9-13(14)2/h5-12,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416890
(CHEMBL1258291)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccc(OC)c(Br)c1 |r| Show InChI InChI=1S/C21H19BrN4O3S/c1-4-17(27)26-15-8-6-5-7-13(15)18-19(23-21(30-3)25-24-18)29-20(26)12-9-10-16(28-2)14(22)11-12/h5-11,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416891
(CHEMBL1258402)Show SMILES CCCOc1ccccc1[C@@H]1Oc2nc(SCC=C)nnc2-c2ccccc2N1C(C)=O |r| Show InChI InChI=1S/C24H24N4O3S/c1-4-14-30-20-13-9-7-11-18(20)23-28(16(3)29)19-12-8-6-10-17(19)21-22(31-23)25-24(27-26-21)32-15-5-2/h5-13,23H,2,4,14-15H2,1,3H3/t23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416892
(CHEMBL1258403)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cc(Cl)ccc1OC |r| Show InChI InChI=1S/C21H19ClN4O3S/c1-4-17(27)26-15-8-6-5-7-13(15)18-19(23-21(30-3)25-24-18)29-20(26)14-11-12(22)9-10-16(14)28-2/h5-11,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 759 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416893
(CHEMBL1258510)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccc(OC)cc1 |r| Show InChI InChI=1S/C21H20N4O3S/c1-4-17(26)25-16-8-6-5-7-15(16)18-19(22-21(29-3)24-23-18)28-20(25)13-9-11-14(27-2)12-10-13/h5-12,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416894
(CHEMBL1258511)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccccc1OC |r| Show InChI InChI=1S/C21H20N4O3S/c1-4-17(26)25-15-11-7-5-9-13(15)18-19(22-21(29-3)24-23-18)28-20(25)14-10-6-8-12-16(14)27-2/h5-12,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 562 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416895
(CHEMBL1258628)Show SMILES CCC(=O)Oc1ccc(Cl)cc1[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(=O)CC |r| Show InChI InChI=1S/C23H21ClN4O4S/c1-4-18(29)28-16-9-7-6-8-14(16)20-21(25-23(33-3)27-26-20)32-22(28)15-12-13(24)10-11-17(15)31-19(30)5-2/h6-12,22H,4-5H2,1-3H3/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416896
(CHEMBL1258629)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cc(OC)ccc1OC |r| Show InChI InChI=1S/C22H22N4O4S/c1-5-18(27)26-16-9-7-6-8-14(16)19-20(23-22(31-4)25-24-19)30-21(26)15-12-13(28-2)10-11-17(15)29-3/h6-12,21H,5H2,1-4H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 191 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416897
(CHEMBL1258737)Show SMILES CCOc1ccc(Br)cc1[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(=O)CC |r| Show InChI InChI=1S/C22H21BrN4O3S/c1-4-18(28)27-16-9-7-6-8-14(16)19-20(24-22(31-3)26-25-19)30-21(27)15-12-13(23)10-11-17(15)29-5-2/h6-12,21H,4-5H2,1-3H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416898
(CHEMBL1258738)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cccc(C)n1 |r| Show InChI InChI=1S/C21H21N5O2S/c1-4-8-17(27)26-16-12-6-5-10-14(16)18-19(23-21(29-3)25-24-18)28-20(26)15-11-7-9-13(2)22-15/h5-7,9-12,20H,4,8H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416899
(CHEMBL1258857)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccc(OC)cc1OC |r| Show InChI InChI=1S/C23H24N4O4S/c1-5-8-19(28)27-17-10-7-6-9-15(17)20-21(24-23(32-4)26-25-20)31-22(27)16-12-11-14(29-2)13-18(16)30-3/h6-7,9-13,22H,5,8H2,1-4H3/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416900
(CHEMBL1258858)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C19H18N4O2S2/c1-3-7-15(24)23-13-9-5-4-8-12(13)16-17(20-19(26-2)22-21-16)25-18(23)14-10-6-11-27-14/h4-6,8-11,18H,3,7H2,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 871 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416901
(CHEMBL1258972)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccc(C)o1 |r| Show InChI InChI=1S/C20H20N4O3S/c1-4-7-16(25)24-14-9-6-5-8-13(14)17-18(21-20(28-3)23-22-17)27-19(24)15-11-10-12(2)26-15/h5-6,8-11,19H,4,7H2,1-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416902
(CHEMBL1258973)Show SMILES CC(=O)N1[C@@H](Oc2nc(SCC=C)nnc2-c2ccccc12)c1cccnc1 |r| Show InChI InChI=1S/C20H17N5O2S/c1-3-11-28-20-22-18-17(23-24-20)15-8-4-5-9-16(15)25(13(2)26)19(27-18)14-7-6-10-21-12-14/h3-10,12,19H,1,11H2,2H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 832 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416903
(CHEMBL1257240)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cccc(OC)c1 |r| Show InChI InChI=1S/C22H22N4O3S/c1-4-8-18(27)26-17-12-6-5-11-16(17)19-20(23-22(30-3)25-24-19)29-21(26)14-9-7-10-15(13-14)28-2/h5-7,9-13,21H,4,8H2,1-3H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416904
(CHEMBL1257241)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccc(C)s1 |r| Show InChI InChI=1S/C19H18N4O2S2/c1-4-15(24)23-13-8-6-5-7-12(13)16-17(20-19(26-3)22-21-16)25-18(23)14-10-9-11(2)27-14/h5-10,18H,4H2,1-3H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416905
(CHEMBL1257362)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H17N5O2S/c1-3-15(25)24-14-10-5-4-8-12(14)16-17(21-19(27-2)23-22-16)26-18(24)13-9-6-7-11-20-13/h4-11,18H,3H2,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7.41E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416906
(CHEMBL1257471)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2cc(Br)ccc2OC)n1 |r| Show InChI InChI=1S/C22H21BrN4O3S/c1-4-18(28)27-16-9-7-6-8-14(16)19-20(24-22(26-25-19)31-5-2)30-21(27)15-12-13(23)10-11-17(15)29-3/h6-12,21H,4-5H2,1-3H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 813 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416907
(CHEMBL1257472)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccccn2)n1 |r| Show InChI InChI=1S/C20H19N5O2S/c1-3-16(26)25-15-11-6-5-9-13(15)17-18(22-20(24-23-17)28-4-2)27-19(25)14-10-7-8-12-21-14/h5-12,19H,3-4H2,1-2H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416908
(CHEMBL1257593)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccc(SC)cc2)n1 |r| Show InChI InChI=1S/C22H22N4O2S2/c1-4-18(27)26-17-9-7-6-8-16(17)19-20(23-22(25-24-19)30-5-2)28-21(26)14-10-12-15(29-3)13-11-14/h6-13,21H,4-5H2,1-3H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416909
(CHEMBL1257594)Show SMILES COc1ccc([C@@H]2Oc3nc(SCC=C)nnc3-c3ccccc3N2C(C)=O)c(OC)c1OC |r| Show InChI InChI=1S/C24H24N4O5S/c1-6-13-34-24-25-22-19(26-27-24)15-9-7-8-10-17(15)28(14(2)29)23(33-22)16-11-12-18(30-3)21(32-5)20(16)31-4/h6-12,23H,1,13H2,2-5H3/t23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7.76E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416910
(CHEMBL1257712)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cccc(C)n1 |r| Show InChI InChI=1S/C20H19N5O2S/c1-4-16(26)25-15-11-6-5-9-13(15)17-18(22-20(28-3)24-23-17)27-19(25)14-10-7-8-12(2)21-14/h5-11,19H,4H2,1-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416911
(CHEMBL1257713)Show SMILES CCC(=O)Oc1ccc(Br)c(c1)[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(=O)CC |r| Show InChI InChI=1S/C23H21BrN4O4S/c1-4-18(29)28-17-9-7-6-8-14(17)20-21(25-23(33-3)27-26-20)32-22(28)15-12-13(10-11-16(15)24)31-19(30)5-2/h6-12,22H,4-5H2,1-3H3/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416912
(CHEMBL1257835)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2cccs2)n1 |r| Show InChI InChI=1S/C19H18N4O2S2/c1-3-15(24)23-13-9-6-5-8-12(13)16-17(20-19(22-21-16)26-4-2)25-18(23)14-10-7-11-27-14/h5-11,18H,3-4H2,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 309 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416913
(CHEMBL1257836)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccco2)n1 |r| Show InChI InChI=1S/C19H18N4O3S/c1-3-15(24)23-13-9-6-5-8-12(13)16-17(20-19(22-21-16)27-4-2)26-18(23)14-10-7-11-25-14/h5-11,18H,3-4H2,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 813 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416914
(CHEMBL1257950)Show SMILES CC(=O)N1[C@@H](Oc2nc(SCC=C)nnc2-c2ccccc12)c1sccc1C |r| Show InChI InChI=1S/C20H18N4O2S2/c1-4-10-28-20-21-18-16(22-23-20)14-7-5-6-8-15(14)24(13(3)25)19(26-18)17-12(2)9-11-27-17/h4-9,11,19H,1,10H2,2-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 457 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416915
(CHEMBL1257951)Show SMILES CCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cc2OCOc2cc1Cl |r| Show InChI InChI=1S/C21H17ClN4O4S/c1-3-17(27)26-14-7-5-4-6-11(14)18-19(23-21(31-2)25-24-18)30-20(26)12-8-15-16(9-13(12)22)29-10-28-15/h4-9,20H,3,10H2,1-2H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416916
(CHEMBL1258062)Show SMILES CSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2cccc(OCc3ccccc3)c2)n1 |r| Show InChI InChI=1S/C26H22N4O3S/c1-17(31)30-22-14-7-6-13-21(22)23-24(27-26(34-2)29-28-23)33-25(30)19-11-8-12-20(15-19)32-16-18-9-4-3-5-10-18/h3-15,25H,16H2,1-2H3/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416917
(CHEMBL1258063)Show SMILES CCCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccccc2F)n1 |r| Show InChI InChI=1S/C22H21FN4O2S/c1-3-13-30-22-24-20-19(25-26-22)15-10-6-8-12-17(15)27(18(28)4-2)21(29-20)14-9-5-7-11-16(14)23/h5-12,21H,3-4,13H2,1-2H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 646 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416918
(CHEMBL1258179)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1cccnc1 |r| Show InChI InChI=1S/C20H19N5O2S/c1-3-7-16(26)25-15-10-5-4-9-14(15)17-18(22-20(28-2)24-23-17)27-19(25)13-8-6-11-21-12-13/h4-6,8-12,19H,3,7H2,1-2H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.89E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416919
(CHEMBL1258180)Show SMILES CCCC(=O)N1[C@@H](Oc2nc(SC)nnc2-c2ccccc12)c1sccc1C |r| Show InChI InChI=1S/C20H20N4O2S2/c1-4-7-15(25)24-14-9-6-5-8-13(14)16-18(21-20(27-3)23-22-16)26-19(24)17-12(2)10-11-28-17/h5-6,8-11,19H,4,7H2,1-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416920
(CHEMBL1255601)Show SMILES CCCCSc1nnc-2c(O[C@@H](CC)N(C(C)=O)c3ccccc-23)n1 |r| Show InChI InChI=1S/C18H22N4O2S/c1-4-6-11-25-18-19-17-16(20-21-18)13-9-7-8-10-14(13)22(12(3)23)15(5-2)24-17/h7-10,15H,4-6,11H2,1-3H3/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416921
(CHEMBL1258292)Show SMILES CCCSc1nnc-2c(O[C@@H](CC)N(C(C)=O)c3ccccc-23)n1 |r| Show InChI InChI=1S/C17H20N4O2S/c1-4-10-24-17-18-16-15(19-20-17)12-8-6-7-9-13(12)21(11(3)22)14(5-2)23-16/h6-9,14H,4-5,10H2,1-3H3/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416922
(CHEMBL1258293)Show SMILES CCSc1nnc-2c(O[C@@H](C)N(C(C)=O)c3ccccc-23)n1 |r| Show InChI InChI=1S/C15H16N4O2S/c1-4-22-15-16-14-13(17-18-15)11-7-5-6-8-12(11)19(9(2)20)10(3)21-14/h5-8,10H,4H2,1-3H3/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416923
(CHEMBL1258404)Show SMILES COc1ccc(cc1)[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(C)=O |r| Show InChI InChI=1S/C20H18N4O3S/c1-12(25)24-16-7-5-4-6-15(16)17-18(21-20(28-3)23-22-17)27-19(24)13-8-10-14(26-2)11-9-13/h4-11,19H,1-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416924
(CHEMBL1258405)Show SMILES CSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccccc2F)n1 |r| Show InChI InChI=1S/C19H15FN4O2S/c1-11(25)24-15-10-6-4-8-13(15)16-17(21-19(27-2)23-22-16)26-18(24)12-7-3-5-9-14(12)20/h3-10,18H,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416925
(CHEMBL1258512)Show SMILES CC(=O)N1[C@@H](Oc2nc(SCC=C)nnc2-c2ccccc12)c1ccc(C)s1 |r| Show InChI InChI=1S/C20H18N4O2S2/c1-4-11-27-20-21-18-17(22-23-20)14-7-5-6-8-15(14)24(13(3)25)19(26-18)16-10-9-12(2)28-16/h4-10,19H,1,11H2,2-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 331 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416926
(CHEMBL1258513)Show SMILES CSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(Br)cc2)n1 |r| Show InChI InChI=1S/C19H15BrN4O2S/c1-11(25)24-15-6-4-3-5-14(15)16-17(21-19(27-2)23-22-16)26-18(24)12-7-9-13(20)10-8-12/h3-10,18H,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416927
(CHEMBL1258630)Show SMILES CCOc1ccccc1[C@@H]1Oc2nc(SC)nnc2-c2ccccc2N1C(C)=O |r| Show InChI InChI=1S/C21H20N4O3S/c1-4-27-17-12-8-6-10-15(17)20-25(13(2)26)16-11-7-5-9-14(16)18-19(28-20)22-21(29-3)24-23-18/h5-12,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416928
(CHEMBL1258631)Show SMILES CSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(Cl)cc2)n1 |r| Show InChI InChI=1S/C19H15ClN4O2S/c1-11(25)24-15-6-4-3-5-14(15)16-17(21-19(27-2)23-22-16)26-18(24)12-7-9-13(20)10-8-12/h3-10,18H,1-2H3/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416929
(CHEMBL1258739)Show SMILES CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2cccn2C)n1 |r| Show InChI InChI=1S/C20H21N5O2S/c1-4-16(26)25-14-10-7-6-9-13(14)17-18(21-20(23-22-17)28-5-2)27-19(25)15-11-8-12-24(15)3/h6-12,19H,4-5H2,1-3H3/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416930
(CHEMBL1258740)Show SMILES CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(OC)c(Br)c2)n1 |r| Show InChI InChI=1S/C21H19BrN4O3S/c1-4-30-21-23-19-18(24-25-21)14-7-5-6-8-16(14)26(12(2)27)20(29-19)13-9-10-17(28-3)15(22)11-13/h5-11,20H,4H2,1-3H3/t20-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 955 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416931
(CHEMBL1258859)Show SMILES CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(OC)cc2OC)n1 |r| Show InChI InChI=1S/C22H22N4O4S/c1-5-31-22-23-20-19(24-25-22)15-8-6-7-9-17(15)26(13(2)27)21(30-20)16-11-10-14(28-3)12-18(16)29-4/h6-12,21H,5H2,1-4H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416932
(CHEMBL1258860)Show SMILES CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(OCc3ccccc3)cc2)n1 |r| Show InChI InChI=1S/C27H24N4O3S/c1-3-35-27-28-25-24(29-30-27)22-11-7-8-12-23(22)31(18(2)32)26(34-25)20-13-15-21(16-14-20)33-17-19-9-5-4-6-10-19/h4-16,26H,3,17H2,1-2H3/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.03E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416933
(CHEMBL1258974)Show SMILES CCOc1cc(ccc1OC(C)=O)[C@@H]1Oc2nc(SCC)nnc2-c2ccccc2N1C(C)=O |r| Show InChI InChI=1S/C24H24N4O5S/c1-5-31-20-13-16(11-12-19(20)32-15(4)30)23-28(14(3)29)18-10-8-7-9-17(18)21-22(33-23)25-24(27-26-21)34-6-2/h7-13,23H,5-6H2,1-4H3/t23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50416934
(CHEMBL1258975)Show SMILES CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2cc(Cl)ccc2OC(C)=O)n1 |r| Show InChI InChI=1S/C22H19ClN4O4S/c1-4-32-22-24-20-19(25-26-22)15-7-5-6-8-17(15)27(12(2)28)21(31-20)16-11-14(23)9-10-18(16)30-13(3)29/h5-11,21H,4H2,1-3H3/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells |
Bioorg Med Chem Lett 20: 5922-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3 |
More data for this Ligand-Target Pair | |