Compile Data Set for Download or QSAR

Found 780 hits with Last Name = 'lee' and Initial = 'hm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398495 (US10323018, Compound I-224) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cncn1C)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-3-32-24-14-22(17-6-9-19(26)10-7-17)29-23-13-18(8-11-21(23)24)25(31)28-12-4-5-20-15-27-16-30(20)2/h6-11,13-16H,3-5,12H2,1-2H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398498 (US10323018, Compound I-227) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ccc(C)nc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H26FN3O2/c1-3-33-26-16-24(20-8-11-22(28)12-9-20)31-25-15-21(10-13-23(25)26)27(32)29-14-4-5-19-7-6-18(2)30-17-19/h6-13,15-17H,3-5,14H2,1-2H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398499 (US10323018, Compound I-228) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cncnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN4O2/c1-2-32-24-13-22(18-5-8-20(26)9-6-18)30-23-12-19(7-10-21(23)24)25(31)29-11-3-4-17-14-27-16-28-15-17/h5-10,12-16H,2-4,11H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398500 (US10323018, Compound I-229) Show SMILES OCCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O3/c25-18-6-3-16(4-7-18)20-15-22(32-13-12-30)19-8-5-17(14-21(19)29-20)24(31)28-9-1-2-23-26-10-11-27-23/h3-8,10-11,14-15,30H,1-2,9,12-13H2,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398419 (US10323018, Compound I-148) Show SMILES Fc1ccc(cc1)-c1cc(-n2ccnc2)c2ccc(cc2n1)C(=O)NCCCc1nnc[nH]1 Show InChI InChI=1S/C24H20FN7O/c25-18-6-3-16(4-7-18)20-13-22(32-11-10-26-15-32)19-8-5-17(12-21(19)30-20)24(33)27-9-1-2-23-28-14-29-31-23/h3-8,10-15H,1-2,9H2,(H,27,33)(H,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398427 (US10323018, Compound I-156) Show SMILES COCCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O3/c1-32-13-14-33-23-16-21(17-4-7-19(26)8-5-17)30-22-15-18(6-9-20(22)23)25(31)29-10-2-3-24-27-11-12-28-24/h4-9,11-12,15-16H,2-3,10,13-14H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398434 (US10323018, Compound I-163) Show SMILES CCCc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O/c1-2-4-18-15-22(17-6-9-20(26)10-7-17)30-23-16-19(8-11-21(18)23)25(31)29-12-3-5-24-27-13-14-28-24/h6-11,13-16H,2-5,12H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398435 (US10323018, Compound I-164) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1cc(OC)ncc1Cl Show InChI InChI=1S/C23H23ClN6O3/c1-3-33-20-11-19(16-10-22(32-2)26-12-17(16)24)29-18-9-14(6-7-15(18)20)23(31)25-8-4-5-21-27-13-28-30-21/h6-7,9-13H,3-5,8H2,1-2H3,(H,25,31)(H,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398438 (US10323018, Compound I-167) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(C)nc1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-11-20(17-5-4-15(2)27-12-17)29-21-10-16(6-7-18(21)23)25(32)28-14-24-30-19-8-9-26-13-22(19)31-24/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398445 (US10323018, Compound I-174) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(C)nc1OC Show InChI InChI=1S/C26H24N6O3/c1-4-35-23-12-21(18-7-5-15(2)29-26(18)34-3)30-20-11-16(6-8-17(20)23)25(33)28-14-24-31-19-9-10-27-13-22(19)32-24/h5-13H,4,14H2,1-3H3,(H,28,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398446 (US10323018, Compound I-175) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H18ClN5O2S/c1-2-31-19-10-17(20-5-6-21(24)32-20)27-16-9-13(3-4-14(16)19)23(30)26-12-22-28-15-7-8-25-11-18(15)29-22/h3-11H,2,12H2,1H3,(H,26,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398449 (US10323018, Compound I-178) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2n1C)-c1ccc(F)cc1 Show InChI InChI=1S/C26H22FN5O2/c1-3-34-24-13-20(16-4-7-18(27)8-5-16)30-21-12-17(6-9-19(21)24)26(33)29-15-25-31-22-14-28-11-10-23(22)32(25)2/h4-14H,3,15H2,1-2H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398458 (US10323018, Compound I-187) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1cc(F)ccc1OC Show InChI InChI=1S/C26H22FN5O3/c1-3-35-24-12-21(18-11-16(27)5-7-23(18)34-2)30-20-10-15(4-6-17(20)24)26(33)29-14-25-31-19-8-9-28-13-22(19)32-25/h4-13H,3,14H2,1-2H3,(H,29,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398459 (US10323018, Compound I-188) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1cc(OC)ncc1F Show InChI InChI=1S/C25H21FN6O3/c1-3-35-22-10-20(16-9-24(34-2)28-11-17(16)26)30-19-8-14(4-5-15(19)22)25(33)29-13-23-31-18-6-7-27-12-21(18)32-23/h4-12H,3,13H2,1-2H3,(H,29,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398463 (US10323018, Compound I-192) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2ccncc2[nH]1)-c1cccnc1OC Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-12-20(17-5-4-9-27-25(17)33-2)29-19-11-15(6-7-16(19)22)24(32)28-14-23-30-18-8-10-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398464 (US10323018, Compound I-193) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(OC)nc1 Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-11-19(16-5-7-24(33-2)27-12-16)29-20-10-15(4-6-17(20)22)25(32)28-14-23-30-18-8-9-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398465 (US10323018, Compound I-194) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccnc(OC)c1 Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-12-19(15-6-9-27-24(11-15)33-2)29-20-10-16(4-5-17(20)22)25(32)28-14-23-30-18-7-8-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398467 (US10323018, Compound I-196) Show SMILES COc1cc(ccn1)-c1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H23FN6O2/c1-36-24-16-18(10-12-31-24)25-21-9-6-19(27(35)32-11-2-3-23-29-13-14-30-23)15-22(21)33-26(34-25)17-4-7-20(28)8-5-17/h4-10,12-16H,2-3,11H2,1H3,(H,29,30)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398469 (US10323018, Compound I-198) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H22ClN5O2/c1-2-31-21-13-19(15-5-8-17(24)9-6-15)28-20-12-16(7-10-18(20)21)23(30)25-11-3-4-22-26-14-27-29-22/h5-10,12-14H,2-4,11H2,1H3,(H,25,30)(H,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398472 (US10323018, Compound I-201) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1c[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-3-32-24-14-22(17-6-9-20(26)10-7-17)29-23-13-18(8-11-21(23)24)25(31)27-12-4-5-19-15-28-30-16(19)2/h6-11,13-15H,3-5,12H2,1-2H3,(H,27,31)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398474 (US10323018, Compound I-203) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1n[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-3-31-22-13-20(15-4-7-17(24)8-5-15)26-21-12-16(6-9-18(21)22)23(30)25-11-10-19-14(2)27-29-28-19/h4-9,12-13H,3,10-11H2,1-2H3,(H,25,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398475 (US10323018, Compound I-204) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cc[nH]n1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-2-31-23-15-21(16-5-8-18(25)9-6-16)28-22-14-17(7-10-20(22)23)24(30)26-12-3-4-19-11-13-27-29-19/h5-11,13-15H,2-4,12H2,1H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398343 (US10323018, Compound I-72) Show SMILES CC[C@@H](F)c1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398344 (US10323018, Compound I-73) Show SMILES CCOc1c(F)c(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H21F2N5O2/c1-2-32-22-18-10-7-15(23(31)26-11-3-4-17-13-27-30-29-17)12-19(18)28-21(20(22)25)14-5-8-16(24)9-6-14/h5-10,12-13H,2-4,11H2,1H3,(H,26,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398345 (US10323018, Compound I-74) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccc2ncnn2c1)-c1ccnc(C)c1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-12-21(18-8-9-26-16(2)10-18)30-22-11-19(5-6-20(22)23)25(32)27-13-17-4-7-24-28-15-29-31(24)14-17/h4-12,14-15H,3,13H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398349 (US10323018, Compound I-78) Show SMILES CCOc1c(F)c(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H21F2N5O2/c1-2-32-22-17-10-7-15(23(31)26-11-3-4-19-27-13-28-30-19)12-18(17)29-21(20(22)25)14-5-8-16(24)9-6-14/h5-10,12-13H,2-4,11H2,1H3,(H,26,31)(H,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398350 (US10323018, Compound I-79) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1cc2cnccc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H20FN3O2S/c1-2-32-24-13-22(16-3-6-19(27)7-4-16)30-23-12-17(5-8-21(23)24)26(31)29-15-20-11-18-14-28-10-9-25(18)33-20/h3-14H,2,15H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398351 (US10323018, Compound I-80) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1cc2[nH]ncc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H19FN4O2S/c1-2-31-22-11-19(14-3-6-16(25)7-4-14)28-20-9-15(5-8-18(20)22)24(30)26-12-17-10-21-23(32-17)13-27-29-21/h3-11,13H,2,12H2,1H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398353 (US10323018, Compound I-82) Show SMILES COCCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H22FN5O3/c1-34-10-11-35-24-14-22(18-2-5-20(27)6-3-18)31-23-13-19(4-7-21(23)24)26(33)28-15-17-8-9-32-25(12-17)29-16-30-32/h2-9,12-14,16H,10-11,15H2,1H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398355 (US10323018, Compound I-84) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccc2ncnn2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-23-12-21(17-4-7-19(26)8-5-17)30-22-11-18(6-9-20(22)23)25(32)27-13-16-3-10-24-28-15-29-31(24)14-16/h3-12,14-15H,2,13H2,1H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398356 (US10323018, Compound I-85) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1OC Show InChI InChI=1S/C26H22FN5O3/c1-3-35-24-13-22(19-7-5-18(27)12-23(19)34-2)31-21-11-17(4-6-20(21)24)26(33)28-14-16-8-9-32-25(10-16)29-15-30-32/h4-13,15H,3,14H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398357 (US10323018, Compound I-86) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccnc(C)c1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-13-21(18-6-8-26-16(2)10-18)30-22-12-19(4-5-20(22)23)25(32)27-14-17-7-9-31-24(11-17)28-15-29-31/h4-13,15H,3,14H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398366 (US10323018, Compound I-95) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccn(C)c(=O)c1 Show InChI InChI=1S/C23H24N6O3/c1-3-32-21-13-19(15-8-10-29(2)22(30)12-15)26-20-11-16(6-7-18(20)21)23(31)24-9-4-5-17-14-25-28-27-17/h6-8,10-14H,3-5,9H2,1-2H3,(H,24,31)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398367 (US10323018, Compound I-96) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(=O)n(C)c1 Show InChI InChI=1S/C23H24N6O3/c1-3-32-21-12-19(16-7-9-22(30)29(2)14-16)26-20-11-15(6-8-18(20)21)23(31)24-10-4-5-17-13-25-28-27-17/h6-9,11-14H,3-5,10H2,1-2H3,(H,24,31)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398370 (US10323018, Compound I-99) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccnc(C)c1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-12-20(16-6-9-27-15(2)10-16)29-21-11-17(4-5-18(21)23)25(32)28-14-24-30-19-7-8-26-13-22(19)31-24/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398373 (US10323018, Compound I-102) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(OC)nc1 Show InChI InChI=1S/C23H24N6O3/c1-3-32-21-12-19(16-7-9-22(31-2)25-13-16)27-20-11-15(6-8-18(20)21)23(30)24-10-4-5-17-14-26-29-28-17/h6-9,11-14H,3-5,10H2,1-2H3,(H,24,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398378 (US10323018, Compound I-107) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H20FN5O2/c1-2-30-21-12-19(14-3-6-16(23)7-4-14)26-20-11-15(5-8-18(20)21)22(29)24-10-9-17-13-25-28-27-17/h3-8,11-13H,2,9-10H2,1H3,(H,24,29)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398381 (US10323018, Compound I-110) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(C)nc1 Show InChI InChI=1S/C23H24N6O2/c1-3-31-22-12-20(17-7-6-15(2)25-13-17)27-21-11-16(8-9-19(21)22)23(30)24-10-4-5-18-14-26-29-28-18/h6-9,11-14H,3-5,10H2,1-2H3,(H,24,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398386 (US10323018, Compound I-115) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-22-13-20(15-5-8-17(24)9-6-15)27-21-12-16(7-10-19(21)22)23(30)25-11-3-4-18-14-26-29-28-18/h5-10,12-14H,2-4,11H2,1H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398387 (US10323018, Compound I-116) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccnc(OC)c1 Show InChI InChI=1S/C23H24N6O3/c1-3-32-21-13-19(15-8-10-24-22(12-15)31-2)27-20-11-16(6-7-18(20)21)23(30)25-9-4-5-17-14-26-29-28-17/h6-8,10-14H,3-5,9H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398388 (US10323018, Compound I-117) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccnc(C)c1 Show InChI InChI=1S/C23H24N6O2/c1-3-31-22-13-20(16-8-10-24-15(2)11-16)27-21-12-17(6-7-19(21)22)23(30)25-9-4-5-18-14-26-29-28-18/h6-8,10-14H,3-5,9H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398392 (US10323018, Compound I-121) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1OC Show InChI InChI=1S/C24H24FN5O3/c1-3-33-23-13-21(18-9-7-16(25)12-22(18)32-2)28-20-11-15(6-8-19(20)23)24(31)26-10-4-5-17-14-27-30-29-17/h6-9,11-14H,3-5,10H2,1-2H3,(H,26,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398396 (US10323018, Compound I-125) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(Cl)s1 Show InChI InChI=1S/C21H20ClN5O2S/c1-2-29-17-11-16(18-7-8-19(22)30-18)26-15-10-13(5-6-14(15)17)21(28)23-9-3-4-20-24-12-25-27-20/h5-8,10-12H,2-4,9H2,1H3,(H,23,28)(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398401 (US10323018, Compound I-130) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-23-13-21(17-3-6-19(26)7-4-17)30-22-12-18(5-8-20(22)23)25(32)27-14-16-9-10-31-24(11-16)28-15-29-31/h3-13,15H,2,14H2,1H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398403 (US10323018, Compound I-132) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1c[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-3-31-23-13-21(16-4-7-19(25)8-5-16)28-22-12-17(6-9-20(22)23)24(30)26-11-10-18-14-27-29-15(18)2/h4-9,12-14H,3,10-11H2,1-2H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398404 (US10323018, Compound I-133) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1n[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN5O2/c1-3-32-23-14-21(16-6-9-18(25)10-7-16)27-22-13-17(8-11-19(22)23)24(31)26-12-4-5-20-15(2)28-30-29-20/h6-11,13-14H,3-5,12H2,1-2H3,(H,26,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398407 (US10323018, Compound I-136) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1cc(C)nc(OC)c1 Show InChI InChI=1S/C24H26N6O3/c1-4-33-21-13-19(17-10-15(2)28-23(12-17)32-3)29-20-11-16(7-8-18(20)21)24(31)25-9-5-6-22-26-14-27-30-22/h7-8,10-14H,4-6,9H2,1-3H3,(H,25,31)(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398264 (US10323018, Compound I-1) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCc1cncn1C)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H24ClN5O/c1-3-4-21-20-10-7-17(24(31)27-12-11-19-14-26-15-30(19)2)13-22(20)29-23(28-21)16-5-8-18(25)9-6-16/h5-10,13-15H,3-4,11-12H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398265 (US10323018, Compound I-2) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1cncn1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-3-31-23-13-21(16-4-7-18(25)8-5-16)28-22-12-17(6-9-20(22)23)24(30)27-11-10-19-14-26-15-29(19)2/h4-9,12-15H,3,10-11H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398267 (US10323018, Compound I-4) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H24ClN5O/c1-2-4-20-19-11-8-17(24(31)28-12-3-5-22-26-13-14-27-22)15-21(19)30-23(29-20)16-6-9-18(25)10-7-16/h6-11,13-15H,2-5,12H2,1H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair

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