BindingDB PrimarySearch

Found 23 hits with Last Name = 'liparulo' and Initial = 'i'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515598 (CHEMBL4526049) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515600 (CHEMBL4580044) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515599 (CHEMBL4457426) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515598 (CHEMBL4526049) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515600 (CHEMBL4580044) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515599 (CHEMBL4457426) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50515598 (CHEMBL4526049) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	323	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholinesterase (Homo sapiens (Human))	BDBM50515601 (CHEMBL4527729) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	535	n/a	n/a	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50597595 (CHEMBL5190179) Show SMILES OCCCCCCCCc1ccc(CN2CCCCCC2)c(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50139053 (CHEMBL3752227) Show SMILES CCN(CCCCCCCCc1cccc(OC)c1)Cc1ccccc1OC Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50597594 (CHEMBL5183866) Show SMILES OCCCCCCCCc1ccc(CN2CCCCC2)c(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50597596 (CHEMBL5195029) Show SMILES CN(Cc1ccccc1)Cc1ccc(CCCCCCCCO)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50597593 (CHEMBL5192958) Show SMILES OCCCCCCCCc1ccc(CN2CCCC2)c(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50597597 (CHEMBL5176423) Show SMILES CCN(CC)Cc1ccc(CCCCCCCCO)cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50597594 (CHEMBL5183866) Show SMILES OCCCCCCCCc1ccc(CN2CCCCC2)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50597593 (CHEMBL5192958) Show SMILES OCCCCCCCCc1ccc(CN2CCCC2)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50597595 (CHEMBL5190179) Show SMILES OCCCCCCCCc1ccc(CN2CCCCCC2)c(O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00046b BindingDB Entry DOI: 10.7270/Q2WM1JG5
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515600 (CHEMBL4580044) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515598 (CHEMBL4526049) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50515599 (CHEMBL4457426) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
Normandie Univ Curated by ChEMBL					Assay Description Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111596 BindingDB Entry DOI: 10.7270/Q2988BC8
Normandie Univ Curated by ChEMBL					More data for this Ligand-Target Pair