Compile Data Set for Download or QSAR

Found 495 hits with Last Name = 'hermans' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM43339 (4-amino-1-naphthalenol;hydrochloride | 4-amino-1-n...) Show SMILES Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H9NO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as...				Eur J Med Chem 136: 480-486 (2017) Article DOI: 10.1016/j.ejmech.2017.05.015 BindingDB Entry DOI: 10.7270/Q20Z75S9
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT8 (Homo sapiens (Human))	BDBM43339 (4-amino-1-naphthalenol;hydrochloride | 4-amino-1-n...) Show SMILES Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H9NO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as...				Eur J Med Chem 136: 480-486 (2017) Article DOI: 10.1016/j.ejmech.2017.05.015 BindingDB Entry DOI: 10.7270/Q20Z75S9
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307231 (1-(4-Cyanobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...) Show SMILES N#Cc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C17H13N3/c18-10-14-6-8-15(9-7-14)12-20-13-19-11-17(20)16-4-2-1-3-5-16/h1-9,11,13H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50518833 (CHEMBL4528993 | US10829446, Compound 45) Show SMILES Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H14FN3O3S/c19-15-11-13(17-8-4-5-9-20-17)10-14(12-15)18(23)21-22-26(24,25)16-6-2-1-3-7-16/h1-12,22H,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics CRC Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 62: 7146-7159 (2019) Article DOI: 10.1021/acs.jmedchem.9b00665 BindingDB Entry DOI: 10.7270/Q26D5XCM
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307242 (1-(4-Cyanobenzyl)-5-(2-fluorophenyl)-1H-imidazole ...) Show SMILES Fc1ccccc1-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C17H12FN3/c18-16-4-2-1-3-15(16)17-10-20-12-21(17)11-14-7-5-13(9-19)6-8-14/h1-8,10,12H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307220 (CHEMBL591229 | Methyl 3-[1-(4-Cyanobenzyl)-1H-imid...) Show SMILES COC(=O)CCc1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C15H15N3O2/c1-20-15(19)7-6-14-9-17-11-18(14)10-13-4-2-12(8-16)3-5-13/h2-5,9,11H,6-7,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM308131 (US9649309, Compound UNC2876A) Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CC3CC3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.25,wD:27.29,(-10.11,-3.85,;-8.77,-3.08,;-7.44,-3.85,;-6.1,-3.08,;-4.77,-3.85,;-3.44,-3.08,;-2.1,-3.85,;-.77,-3.08,;-.77,-1.54,;.56,-.77,;.56,.77,;1.9,-1.54,;3.23,-.77,;4.56,-1.54,;5.9,-.77,;5.9,.77,;7.23,1.54,;8.57,.77,;9.34,-.56,;10.11,.77,;4.56,1.54,;3.23,.77,;-2.1,-.77,;-2.1,.77,;-3.44,1.54,;-4.77,.77,;-6.1,1.54,;-6.1,3.08,;-7.44,3.85,;-4.77,3.85,;-3.44,3.08,;-3.44,-1.54,)| Show InChI InChI=1S/C24H40N6O2/c1-2-3-12-25-24-26-15-21(22(29-24)27-18-6-8-20(31)9-7-18)23(32)28-19-10-13-30(14-11-19)16-17-4-5-17/h15,17-20,31H,2-14,16H2,1H3,(H,28,32)(H2,25,26,27,29)/t18-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113822 BindingDB Entry DOI: 10.7270/Q2TX3KFC
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307243 (1-(4-Cyanobenzyl)-5-(2-methylphenyl)-1H-imidazole ...) Show SMILES Cc1ccccc1-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C18H15N3/c1-14-4-2-3-5-17(14)18-11-20-13-21(18)12-16-8-6-15(10-19)7-9-16/h2-9,11,13H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307223 (CHEMBL592614 | Methyl 3-[1-(4-Bromobenzyl)-1H-imid...) Show SMILES COC(=O)CCc1cncn1Cc1ccc(Br)cc1 Show InChI InChI=1S/C14H15BrN2O2/c1-19-14(18)7-6-13-8-16-10-17(13)9-11-2-4-12(15)5-3-11/h2-5,8,10H,6-7,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50602486 (CHEMBL5196154) Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:24.24,wD:27.28,(26.44,-12.6,;27.77,-11.83,;29.1,-12.6,;30.44,-11.83,;31.77,-12.6,;33.11,-11.83,;34.44,-12.6,;35.78,-11.83,;35.77,-10.28,;37.1,-9.51,;37.1,-7.97,;38.44,-10.27,;39.77,-9.5,;41.1,-10.27,;42.43,-9.5,;42.43,-7.96,;43.77,-7.19,;45.1,-7.96,;46.43,-7.19,;47.77,-7.96,;41.1,-7.19,;39.76,-7.96,;34.44,-9.52,;34.43,-7.98,;33.1,-7.21,;31.77,-7.98,;30.43,-7.21,;30.43,-5.67,;29.1,-4.9,;31.77,-4.9,;33.1,-5.67,;33.11,-10.29,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113822 BindingDB Entry DOI: 10.7270/Q2TX3KFC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50602485 (CHEMBL5171919) Show SMILES CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113822 BindingDB Entry DOI: 10.7270/Q2TX3KFC
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM24655 (1-benzyl-5-phenyl-1H-imidazole | 4-phenylimidazole...) Show SMILES C(c1ccccc1)n1cncc1-c1ccccc1 Show InChI InChI=1S/C16H14N2/c1-3-7-14(8-4-1)12-18-13-17-11-16(18)15-9-5-2-6-10-15/h1-11,13H,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527224 (CHEMBL4468833 | US10829446, Compound 48) Show SMILES COc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C19H16FN3O4S/c1-27-15-11-13(17-7-4-5-9-21-17)10-14(12-15)19(24)22-23-28(25,26)18-8-3-2-6-16(18)20/h2-12,23H,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307234 (1-(4-Bromobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...) Show SMILES Brc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C16H13BrN2/c17-15-8-6-13(7-9-15)11-19-12-18-10-16(19)14-4-2-1-3-5-14/h1-10,12H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307245 (1-(4-Cyanobenzyl)-5-(3-methylphenyl)-1H-imidazole ...) Show SMILES Cc1cccc(c1)-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C18H15N3/c1-14-3-2-4-17(9-14)18-11-20-13-21(18)12-16-7-5-15(10-19)6-8-16/h2-9,11,13H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307244 (1-(4-Cyanobenzyl)-5-(3-fluorophenyl)-1H-imidazole ...) Show SMILES Fc1cccc(c1)-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C17H12FN3/c18-16-3-1-2-15(8-16)17-10-20-12-21(17)11-14-6-4-13(9-19)5-7-14/h1-8,10,12H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527244 (CHEMBL4437798 | US10829446, Compound 105) Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cc(Cl)cc(c1)-c1ccco1 Show InChI InChI=1S/C17H12ClFN2O4S/c18-13-9-11(15-5-3-7-25-15)8-12(10-13)17(22)20-21-26(23,24)16-6-2-1-4-14(16)19/h1-10,21H,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307243 (1-(4-Cyanobenzyl)-5-(2-methylphenyl)-1H-imidazole ...) Show SMILES Cc1ccccc1-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C18H15N3/c1-14-4-2-3-5-17(14)18-11-20-13-21(18)12-16-8-6-15(10-19)7-9-16/h2-9,11,13H,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307233 (1-(4-Chlorobenzyl)-5-phenyl-1H-imidazole | CHEMBL5...) Show SMILES Clc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C16H13ClN2/c17-15-8-6-13(7-9-15)11-19-12-18-10-16(19)14-4-2-1-3-5-14/h1-10,12H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527381 (CHEMBL4466823 | US10829446, Compound 41) Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccccn1 Show InChI InChI=1S/C18H14FN3O3S/c19-15-8-1-2-10-17(15)26(24,25)22-21-18(23)14-7-5-6-13(12-14)16-9-3-4-11-20-16/h1-12,22H,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50047262 ((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...) Show SMILES N#Cc1ccc(cc1)[C@H]1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307245 (1-(4-Cyanobenzyl)-5-(3-methylphenyl)-1H-imidazole ...) Show SMILES Cc1cccc(c1)-c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C18H15N3/c1-14-3-2-4-17(9-14)18-11-20-13-21(18)12-16-7-5-15(10-19)6-8-16/h2-9,11,13H,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307229 (3-[1-(4-Bromobenzyl)-1H-imidazol-5-yl]-1-propanol ...) Show SMILES OCCCc1cncn1Cc1ccc(Br)cc1 Show InChI InChI=1S/C13H15BrN2O/c14-12-5-3-11(4-6-12)9-16-10-15-8-13(16)2-1-7-17/h3-6,8,10,17H,1-2,7,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527355 (CHEMBL4456585 | US10829446, Compound 46) Show SMILES Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307234 (1-(4-Bromobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...) Show SMILES Brc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C16H13BrN2/c17-15-8-6-13(7-9-15)11-19-12-18-10-16(19)14-4-2-1-3-5-14/h1-10,12H,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307237 (1-(4-Cyanobenzyl)-5-(methyl carboxylate)-1H-imidaz...) Show SMILES COC(=O)c1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C13H11N3O2/c1-18-13(17)12-7-15-9-16(12)8-11-4-2-10(6-14)3-5-11/h2-5,7,9H,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527250 (CHEMBL4475883 | US10829446, Compound 67) Show SMILES Cc1ccn(n1)-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H17FN4O3S/c1-12-9-14(11-15(10-12)23-8-7-13(2)21-23)18(24)20-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527238 (CHEMBL4539384 | US10829446, Compound 42) Show SMILES Cc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C19H16FN3O3S/c1-13-10-14(17-7-4-5-9-21-17)12-15(11-13)19(24)22-23-27(25,26)18-8-3-2-6-16(18)20/h2-12,23H,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50518832 (CHEMBL4455897 | US10829446, Compound 36) Show SMILES Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccc1 Show InChI InChI=1S/C20H17FN2O3S/c1-14-12-16(15-8-4-2-5-9-15)13-18(19(14)21)20(24)22-23-27(25,26)17-10-6-3-7-11-17/h2-13,23H,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics CRC Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 62: 7146-7159 (2019) Article DOI: 10.1021/acs.jmedchem.9b00665 BindingDB Entry DOI: 10.7270/Q26D5XCM
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527328 (CHEMBL4441439 | US10829446, Compound 49) Show SMILES Cc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H15FN4O3S/c1-12-9-13(17-20-7-4-8-21-17)11-14(10-12)18(24)22-23-27(25,26)16-6-3-2-5-15(16)19/h2-11,23H,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527245 (CHEMBL4521125 | US10829446, Compound 89) Show SMILES Fc1cc(cc(c1)-n1nccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C15H11F2N5O3S/c16-11-7-10(8-12(9-11)22-18-5-6-19-22)15(23)20-21-26(24,25)14-4-2-1-3-13(14)17/h1-9,21H,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527225 (CHEMBL4565790 | US10829446, Compound 101) Show SMILES Fc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C17H12F2N2O4S/c18-13-9-11(15-5-3-7-25-15)8-12(10-13)17(22)20-21-26(23,24)16-6-2-1-4-14(16)19/h1-10,21H,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50518831 (CHEMBL4464835 | US10829446, Compound 35) Show SMILES Fc1c(Cl)cc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C19H14ClFN2O3S/c20-17-12-14(13-7-3-1-4-8-13)11-16(18(17)21)19(24)22-23-27(25,26)15-9-5-2-6-10-15/h1-12,23H,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics CRC Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 62: 7146-7159 (2019) Article DOI: 10.1021/acs.jmedchem.9b00665 BindingDB Entry DOI: 10.7270/Q26D5XCM
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307235 (1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole | CHEMBL...) Show SMILES COc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O/c1-20-16-9-7-14(8-10-16)12-19-13-18-11-17(19)15-5-3-2-4-6-15/h2-11,13H,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307232 (1-(4-Fluorobenzyl)-5-phenyl-1H-imidazole | CHEMBL6...) Show SMILES Fc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C16H13FN2/c17-15-8-6-13(7-9-15)11-19-12-18-10-16(19)14-4-2-1-3-5-14/h1-10,12H,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527243 (CHEMBL4458272 | US10829446, Compound 153) Show SMILES Cc1cc(cc(c1)-c1ccco1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H15FN2O4S/c1-12-9-13(16-6-4-8-25-16)11-14(10-12)18(22)20-21-26(23,24)17-7-3-2-5-15(17)19/h2-11,21H,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM24655 (1-benzyl-5-phenyl-1H-imidazole | 4-phenylimidazole...) Show SMILES C(c1ccccc1)n1cncc1-c1ccccc1 Show InChI InChI=1S/C16H14N2/c1-3-7-14(8-4-1)12-18-13-17-11-16(18)15-9-5-2-6-10-15/h1-11,13H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50008729 (1-(4-Cyanobenzyl)-5-methyl-1H-imidazole | 4-(5-Met...) Show SMILES Cc1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C12H11N3/c1-10-7-14-9-15(10)8-12-4-2-11(6-13)3-5-12/h2-5,7,9H,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307230 (3-[1-(4-Methoxybenzyl)-1H-imidazol-5-yl]-1-propano...) Show SMILES COc1ccc(Cn2cncc2CCCO)cc1 Show InChI InChI=1S/C14H18N2O2/c1-18-14-6-4-12(5-7-14)10-16-11-15-9-13(16)3-2-8-17/h4-7,9,11,17H,2-3,8,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307226 (3-[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]-1-propanol ...) Show SMILES OCCCc1cncn1Cc1ccc(cc1)C#N Show InChI InChI=1S/C14H15N3O/c15-8-12-3-5-13(6-4-12)10-17-11-16-9-14(17)2-1-7-18/h3-6,9,11,18H,1-2,7,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527263 (CHEMBL4465716 | US10829446, Compound 63) Show SMILES COc1cc(cc(c1)-n1cccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C17H15FN4O4S/c1-26-14-10-12(9-13(11-14)22-8-4-7-19-22)17(23)20-21-27(24,25)16-6-3-2-5-15(16)18/h2-11,21H,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527246 (CHEMBL4445473 | US10829446, Compound 84) Show SMILES Cc1ccnn1-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H17FN4O3S/c1-12-9-14(11-15(10-12)23-13(2)7-8-20-23)18(24)21-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527232 (CHEMBL4436877 | US10829446, Compound 78) Show SMILES Cc1cnn(c1)-c1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C18H17FN4O3S/c1-12-7-14(9-15(8-12)23-11-13(2)10-20-23)18(24)21-22-27(25,26)17-6-4-3-5-16(17)19/h3-11,22H,1-2H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50307235 (1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole | CHEMBL...) Show SMILES COc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O/c1-20-16-9-7-14(8-10-16)12-19-13-18-11-17(19)15-5-3-2-4-6-15/h2-11,13H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527240 (CHEMBL4541948 | US10829446, Compound 124) Show SMILES Fc1ccccc1S(=O)(=O)NNC(=O)c1cccc(c1)-c1ccsc1 Show InChI InChI=1S/C17H13FN2O3S2/c18-15-6-1-2-7-16(15)25(22,23)20-19-17(21)13-5-3-4-12(10-13)14-8-9-24-11-14/h1-11,20H,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527235 (CHEMBL4516984 | US10829446, Compound 52) Show SMILES Fc1cc(cc(c1)-c1ncccn1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C17H12F2N4O3S/c18-13-9-11(16-20-6-3-7-21-16)8-12(10-13)17(24)22-23-27(25,26)15-5-2-1-4-14(15)19/h1-10,23H,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6A [507-778] (Homo sapiens)	BDBM50527366 (CHEMBL4449163 | US10829446, Compound 139) Show SMILES CC(C)Oc1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C17H19FN2O4S/c1-11(2)24-14-9-12(3)8-13(10-14)17(21)19-20-25(22,23)16-7-5-4-6-15(16)18/h4-11,20H,1-3H3,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071 BindingDB Entry DOI: 10.7270/Q2W66Q7V
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50307232 (1-(4-Fluorobenzyl)-5-phenyl-1H-imidazole | CHEMBL6...) Show SMILES Fc1ccc(Cn2cncc2-c2ccccc2)cc1 Show InChI InChI=1S/C16H13FN2/c17-15-8-6-13(7-9-15)11-19-12-18-10-16(19)14-4-2-1-3-5-14/h1-10,12H,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Eindhoven University of Technology Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells				J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF
					More data for this Ligand-Target Pair

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