BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 283 hits with Last Name = 'kishino' and Initial = 'j'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin-H2 D-isomerase


(Homo sapiens (Human))		BDBM50008805
PNG
(7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)...)
Show SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H27NO4S/c22-19(23)11-7-2-1-6-10-18-15-12-13-16(14-15)20(18)21-26(24,25)17-8-4-3-5-9-17/h1,3-6,8-9,15-16,18,20-21H,2,7,10-14H2,(H,22,23)/b6-1-/t15-,16?,18+,20?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.340n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(GUINEA PIG)		BDBM50008805
PNG
(7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)...)
Show SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H27NO4S/c22-19(23)11-7-2-1-6-10-18-15-12-13-16(14-15)20(18)21-26(24,25)17-8-4-3-5-9-17/h1,3-6,8-9,15-16,18,20-21H,2,7,10-14H2,(H,22,23)/b6-1-/t15-,16?,18+,20?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 0.490n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Homo sapiens (Human))		BDBM50060462
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 1.60n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Homo sapiens (Human))		BDBM50060462
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 24.2n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(GUINEA PIG)		BDBM50060462
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 193n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Homo sapiens (Human))		BDBM85347
PNG
(BWA868C | CAS_122021 | NSC_122021)
Show SMILES OC(CNn1c(CCCCCCC(O)=O)c(O)n(Cc2ccccc2)c1=O)C1CCCCC1
Show InChI InChI=1S/C25H37N3O5/c29-22(20-13-7-4-8-14-20)17-26-28-21(15-9-1-2-10-16-23(30)31)24(32)27(25(28)33)18-19-11-5-3-6-12-19/h3,5-6,11-12,20,22,26,29,32H,1-2,4,7-10,13-18H2,(H,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Patents
PubMed
 2.60E+3n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Prostaglandin-H2 D-isomerase


(Homo sapiens (Human))		BDBM50008805
PNG
(7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)...)
Show SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C20H27NO4S/c22-19(23)11-7-2-1-6-10-18-15-12-13-16(14-15)20(18)21-26(24,25)17-8-4-3-5-9-17/h1,3-6,8-9,15-16,18,20-21H,2,7,10-14H2,(H,22,23)/b6-1-/t15-,16?,18+,20?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shionogi & Co.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 411-9 (2001)


BindingDB Entry DOI: 10.7270/Q2028Q3C
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))		BDBM50060458
PNG
((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...)
Show SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H]2CC[C@@H](C2)[C@@H]1NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C24H29NO4S/c26-23(27)10-4-2-1-3-9-22-19-11-12-20(15-19)24(22)25-30(28,29)21-14-13-17-7-5-6-8-18(17)16-21/h1,3,5-8,13-14,16,19-20,22,24-25H,2,4,9-12,15H2,(H,26,27)/b3-1-/t19-,20+,22+,24+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.130n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assay

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060454
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Fluoro-benzo[b]thiophen...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(F)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H30FNO3S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)27-24(30)19-14-31-21-10-9-17(26)13-18(19)21/h3,5,9-10,13-16,20,23H,4,6-8,11-12H2,1-2H3,(H,27,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.270n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060462
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 0.400n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128750
PNG
(7-{2-[(5-Fluoro-benzo[b]thiophene-3-carbonyl)-amin...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(F)cc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H30FNO3S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)27-24(30)19-14-31-21-10-9-17(26)13-18(19)21/h3,5,9-10,13-16,20,23H,4,6-8,11-12H2,1-2H3,(H,27,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.420n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128768
PNG
(7-{2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060462
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060453
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(6-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3cc(O)ccc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-13-17(27)9-10-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060454
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(5-Fluoro-benzo[b]thiophen...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(F)cc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H30FNO3S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)27-24(30)19-14-31-21-10-9-17(26)13-18(19)21/h3,5,9-10,13-16,20,23H,4,6-8,11-12H2,1-2H3,(H,27,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128768
PNG
(7-{2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-10-9-17(27)13-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128767
PNG
(7-{2-[(6-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3cc(O)ccc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-13-17(27)9-10-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060453
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(6-Hydroxy-benzo[b]thiophe...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3cc(O)ccc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-13-17(27)9-10-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3-/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128750
PNG
(7-{2-[(5-Fluoro-benzo[b]thiophene-3-carbonyl)-amin...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(F)cc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H30FNO3S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)27-24(30)19-14-31-21-10-9-17(26)13-18(19)21/h3,5,9-10,13-16,20,23H,4,6-8,11-12H2,1-2H3,(H,27,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.20n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060459
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-7-carbo...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cccc3ccsc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)18-14-17(8-5-3-4-6-11-21(27)28)22(20(25)15-18)26-24(29)19-10-7-9-16-12-13-30-23(16)19/h3,5,7,9-10,12-13,17-18,20,22H,4,6,8,11,14-15H2,1-2H3,(H,26,29)(H,27,28)/b5-3-/t17-,18-,20-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128762
PNG
(7-{2-[(Benzo[b]thiophene-7-carbonyl)-amino]-6,6-di...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cccc3ccsc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)18-14-17(8-5-3-4-6-11-21(27)28)22(20(25)15-18)26-24(29)19-10-7-9-16-12-13-30-23(16)19/h3,5,7,9-10,12-13,17-18,20,22H,4,6,8,11,14-15H2,1-2H3,(H,26,29)(H,27,28)/b5-3+/t17-,18-,20-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060465
PNG
((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1
Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.5n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060465
PNG
((+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bi...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)C#Cc1ccccc1
Show InChI InChI=1S/C28H31NO4S/c30-27(31)11-7-2-1-6-10-26-23-16-17-24(20-23)28(26)29-34(32,33)25-18-14-22(15-19-25)13-12-21-8-4-3-5-9-21/h1,3-6,8-9,14-15,18-19,23-24,26,28-29H,2,7,10-11,16-17,20H2,(H,30,31)/b6-1-/t23-,24+,26+,28+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.60n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128757
PNG
(7-{6,6-Dimethyl-2-[(5-methyl-thiophene-3-carbonyl)...)
Show SMILES Cc1cc(cs1)C(=O)N[C@H]1[C@@H]2C[C@H](C[C@@H]1C\C=C\CCCC(O)=O)C2(C)C
Show InChI InChI=1S/C22H31NO3S/c1-14-10-16(13-27-14)21(26)23-20-15(8-6-4-5-7-9-19(24)25)11-17-12-18(20)22(17,2)3/h4,6,10,13,15,17-18,20H,5,7-9,11-12H2,1-3H3,(H,23,26)(H,24,25)/b6-4+/t15-,17-,18-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128694
PNG
((+) 7-{3-[2-(4-Methoxy-phenyl)-1H-indole-6-sulfony...)
Show SMILES COc1ccc(cc1)-c1cc2ccc(cc2[nH]1)S(=O)(=O)N[C@@H]1[C@@H]2CC[C@@H](C2)[C@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C29H34N2O5S/c1-36-23-13-10-19(11-14-23)26-17-21-12-15-24(18-27(21)30-26)37(34,35)31-29-22-9-8-20(16-22)25(29)6-4-2-3-5-7-28(32)33/h2,4,10-15,17-18,20,22,25,29-31H,3,5-9,16H2,1H3,(H,32,33)/b4-2-/t20-,22+,25+,29+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128738
PNG
(7-{6,6-Dimethyl-2-[(thiophene-2-carbonyl)-amino]-b...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cccs1)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C21H29NO3S/c1-21(2)15-12-14(8-5-3-4-6-10-18(23)24)19(16(21)13-15)22-20(25)17-9-7-11-26-17/h3,5,7,9,11,14-16,19H,4,6,8,10,12-13H2,1-2H3,(H,22,25)(H,23,24)/b5-3+/t14-,15-,16-,19+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128736
PNG
(7-[2-(2-Furan-3-yl-acetylamino)-6,6-dimethyl-bicyc...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)Cc1ccoc1)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C22H31NO4/c1-22(2)17-12-16(7-5-3-4-6-8-20(25)26)21(18(22)13-17)23-19(24)11-15-9-10-27-14-15/h3,5,9-10,14,16-18,21H,4,6-8,11-13H2,1-2H3,(H,23,24)(H,25,26)/b5-3+/t16-,17-,18-,21+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128711
PNG
((+) 7-{3-[2-(4-Hydroxy-phenyl)-1H-indole-6-sulfony...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2cc([nH]c2c1)-c1ccc(O)cc1
Show InChI InChI=1S/C28H32N2O5S/c31-22-12-9-18(10-13-22)25-16-20-11-14-23(17-26(20)29-25)36(34,35)30-28-21-8-7-19(15-21)24(28)5-3-1-2-4-6-27(32)33/h1,3,9-14,16-17,19,21,24,28-31H,2,4-8,15H2,(H,32,33)/b3-1-/t19-,21+,24+,28+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128767
PNG
(7-{2-[(6-Hydroxy-benzo[b]thiophene-3-carbonyl)-ami...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3cc(O)ccc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO4S/c1-25(2)16-11-15(7-5-3-4-6-8-22(28)29)23(20(25)12-16)26-24(30)19-14-31-21-13-17(27)9-10-18(19)21/h3,5,9-10,13-16,20,23,27H,4,6-8,11-12H2,1-2H3,(H,26,30)(H,28,29)/b5-3+/t15-,16-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128744
PNG
(7-{2-[(Benzo[b]thiophene-2-carbonyl)-amino]-6,6-di...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cc3ccccc3s1)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)18-13-17(10-5-3-4-6-12-22(27)28)23(19(25)15-18)26-24(29)21-14-16-9-7-8-11-20(16)30-21/h3,5,7-9,11,14,17-19,23H,4,6,10,12-13,15H2,1-2H3,(H,26,29)(H,27,28)/b5-3+/t17-,18-,19-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128721
PNG
(7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2.2.1]...)
Show SMILES OC(=O)CCCCC(=O)C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2oc3ccccc3c2c1
Show InChI InChI=1S/C26H29NO6S/c28-18(5-1-4-8-25(29)30)14-21-16-9-10-17(13-16)26(21)27-34(31,32)19-11-12-24-22(15-19)20-6-2-3-7-23(20)33-24/h2-3,6-7,11-12,15-17,21,26-27H,1,4-5,8-10,13-14H2,(H,29,30)/t16-,17+,21+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human platelets

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128751
PNG
(7-{6,6-Dimethyl-2-[(2-methyl-thiophene-3-carbonyl)...)
Show SMILES Cc1sccc1C(=O)N[C@H]1[C@@H]2C[C@H](C[C@@H]1C\C=C\CCCC(O)=O)C2(C)C
Show InChI InChI=1S/C22H31NO3S/c1-14-17(10-11-27-14)21(26)23-20-15(8-6-4-5-7-9-19(24)25)12-16-13-18(20)22(16,2)3/h4,6,10-11,15-16,18,20H,5,7-9,12-13H2,1-3H3,(H,23,26)(H,24,25)/b6-4+/t15-,16-,18-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128725
PNG
((+) 7-[3-(9H-Carbazole-3-sulfonylamino)-bicyclo[2....)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2[nH]c3ccccc3c2c1
Show InChI InChI=1S/C26H30N2O4S/c29-25(30)10-4-2-1-3-7-20-17-11-12-18(15-17)26(20)28-33(31,32)19-13-14-24-22(16-19)21-8-5-6-9-23(21)27-24/h1,3,5-6,8-9,13-14,16-18,20,26-28H,2,4,7,10-12,15H2,(H,29,30)/b3-1-/t17-,18+,20+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128725
PNG
((+) 7-[3-(9H-Carbazole-3-sulfonylamino)-bicyclo[2....)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2[nH]c3ccccc3c2c1
Show InChI InChI=1S/C26H30N2O4S/c29-25(30)10-4-2-1-3-7-20-17-11-12-18(15-17)26(20)28-33(31,32)19-13-14-24-22(16-19)21-8-5-6-9-23(21)27-24/h1,3,5-6,8-9,13-14,16-18,20,26-28H,2,4,7,10-12,15H2,(H,29,30)/b3-1-/t17-,18+,20+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human platelets

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128749
PNG
(7-{2-[(Benzo[b]thiophene-3-carbonyl)-amino]-6,6-di...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccccc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)17-13-16(9-5-3-4-6-12-22(27)28)23(20(25)14-17)26-24(29)19-15-30-21-11-8-7-10-18(19)21/h3,5,7-8,10-11,15-17,20,23H,4,6,9,12-14H2,1-2H3,(H,26,29)(H,27,28)/b5-3+/t16-,17-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128693
PNG
((+) 7-[3-(Dibenzofuran-3-sulfonylamino)-bicyclo[2....)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2c(c1)oc1ccccc21
Show InChI InChI=1S/C26H29NO5S/c28-25(29)10-4-2-1-3-7-20-17-11-12-18(15-17)26(20)27-33(30,31)19-13-14-22-21-8-5-6-9-23(21)32-24(22)16-19/h1,3,5-6,8-9,13-14,16-18,20,26-27H,2,4,7,10-12,15H2,(H,28,29)/b3-1-/t17-,18+,20+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060452
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccccc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)17-13-16(9-5-3-4-6-12-22(27)28)23(20(25)14-17)26-24(29)19-15-30-21-11-8-7-10-18(19)21/h3,5,7-8,10-11,15-17,20,23H,4,6,9,12-14H2,1-2H3,(H,26,29)(H,27,28)/b5-3-/t16-,17-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060447
PNG
((+) 7-[3-(2-Methoxy-dibenzofuran-3-sulfonylamino)-...)
Show SMILES COc1cc2c(cc1S(=O)(=O)N[C@@H]1[C@@H]3CC[C@@H](C3)[C@H]1C\C=C/CCCC(O)=O)oc1ccccc21
Show InChI InChI=1S/C27H31NO6S/c1-33-24-15-21-20-9-6-7-10-22(20)34-23(21)16-25(24)35(31,32)28-27-18-13-12-17(14-18)19(27)8-4-2-3-5-11-26(29)30/h2,4,6-7,9-10,15-19,27-28H,3,5,8,11-14H2,1H3,(H,29,30)/b4-2-/t17-,18+,19+,27+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128711
PNG
((+) 7-{3-[2-(4-Hydroxy-phenyl)-1H-indole-6-sulfony...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2cc([nH]c2c1)-c1ccc(O)cc1
Show InChI InChI=1S/C28H32N2O5S/c31-22-12-9-18(10-13-22)25-16-20-11-14-23(17-26(20)29-25)36(34,35)30-28-21-8-7-19(15-21)24(28)5-3-1-2-4-6-27(32)33/h1,3,9-14,16-17,19,21,24,28-31H,2,4-8,15H2,(H,32,33)/b3-1-/t19-,21+,24+,28+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human platelets

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128757
PNG
(7-{6,6-Dimethyl-2-[(5-methyl-thiophene-3-carbonyl)...)
Show SMILES Cc1cc(cs1)C(=O)N[C@H]1[C@@H]2C[C@H](C[C@@H]1C\C=C\CCCC(O)=O)C2(C)C
Show InChI InChI=1S/C22H31NO3S/c1-14-10-16(13-27-14)21(26)23-20-15(8-6-4-5-7-9-19(24)25)11-17-12-18(20)22(17,2)3/h4,6,10,13,15,17-18,20H,5,7-9,11-12H2,1-3H3,(H,23,26)(H,24,25)/b6-4+/t15-,17-,18-,20+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060463
PNG
((+) 7-[3-(4-Phenylazo-benzenesulfonylamino)-bicycl...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)\N=N\c1ccccc1
Show InChI InChI=1S/C26H31N3O4S/c30-25(31)11-7-2-1-6-10-24-19-12-13-20(18-19)26(24)29-34(32,33)23-16-14-22(15-17-23)28-27-21-8-4-3-5-9-21/h1,3-6,8-9,14-17,19-20,24,26,29H,2,7,10-13,18H2,(H,30,31)/b6-1-,28-27+/t19-,20+,24+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060459
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-7-carbo...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cccc3ccsc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)18-14-17(8-5-3-4-6-11-21(27)28)22(20(25)15-18)26-24(29)19-10-7-9-16-12-13-30-23(16)19/h3,5,7,9-10,12-13,17-18,20,22H,4,6,8,11,14-15H2,1-2H3,(H,26,29)(H,27,28)/b5-3-/t17-,18-,20-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128762
PNG
(7-{2-[(Benzo[b]thiophene-7-carbonyl)-amino]-6,6-di...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1cccc3ccsc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)18-14-17(8-5-3-4-6-11-21(27)28)22(20(25)15-18)26-24(29)19-10-7-9-16-12-13-30-23(16)19/h3,5,7,9-10,12-13,17-18,20,22H,4,6,8,11,14-15H2,1-2H3,(H,26,29)(H,27,28)/b5-3+/t17-,18-,20-,22+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060463
PNG
((+) 7-[3-(4-Phenylazo-benzenesulfonylamino)-bicycl...)
Show SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc(cc1)\N=N\c1ccccc1
Show InChI InChI=1S/C26H31N3O4S/c30-25(31)11-7-2-1-6-10-24-19-12-13-20(18-19)26(24)29-34(32,33)23-16-14-22(15-17-23)28-27-21-8-4-3-5-9-21/h1,3-6,8-9,14-17,19-20,24,26,29H,2,7,10-13,18H2,(H,30,31)/b6-1-,28-27+/t19-,20+,24+,26+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060447
PNG
((+) 7-[3-(2-Methoxy-dibenzofuran-3-sulfonylamino)-...)
Show SMILES COc1cc2c(cc1S(=O)(=O)N[C@@H]1[C@@H]3CC[C@@H](C3)[C@H]1C\C=C/CCCC(O)=O)oc1ccccc21
Show InChI InChI=1S/C27H31NO6S/c1-33-24-15-21-20-9-6-7-10-22(20)34-23(21)16-25(24)35(31,32)28-27-18-13-12-17(14-18)19(27)8-4-2-3-5-11-26(29)30/h2,4,6-7,9-10,15-19,27-28H,3,5,8,11-14H2,1H3,(H,29,30)/b4-2-/t17-,18+,19+,27+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128769
PNG
(7-{2-[(5-Methanesulfonylamino-benzo[b]thiophene-3-...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(NS(C)(=O)=O)cc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C26H34N2O5S2/c1-26(2)17-12-16(8-6-4-5-7-9-23(29)30)24(21(26)13-17)27-25(31)20-15-34-22-11-10-18(14-19(20)22)28-35(3,32)33/h4,6,10-11,14-17,21,24,28H,5,7-9,12-13H2,1-3H3,(H,27,31)(H,29,30)/b6-4+/t16-,17-,21-,24+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required to inhibit the PGD-2 evoked cAMP formation in human platelets

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128712
PNG
(CHEMBL309443 | Dibenzofuran-2-sulfonic acid [3-(7-...)
Show SMILES CS(=O)(=O)NC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2oc3ccccc3c2c1
Show InChI InChI=1S/C27H32N2O6S2/c1-36(31,32)28-26(30)11-5-3-2-4-8-21-18-12-13-19(16-18)27(21)29-37(33,34)20-14-15-25-23(17-20)22-9-6-7-10-24(22)35-25/h2,4,6-7,9-10,14-15,17-19,21,27,29H,3,5,8,11-13,16H2,1H3,(H,28,30)/b4-2-/t18-,19+,21+,27+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human platelets

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128749
PNG
(7-{2-[(Benzo[b]thiophene-3-carbonyl)-amino]-6,6-di...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccccc13)[C@@H](C\C=C\CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)17-13-16(9-5-3-4-6-12-22(27)28)23(20(25)14-17)26-24(29)19-15-30-21-11-8-7-10-18(19)21/h3,5,7-8,10-11,15-17,20,23H,4,6,9,12-14H2,1-2H3,(H,26,29)(H,27,28)/b5-3+/t16-,17-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranes

J Med Chem 46: 2446-55 (2003)


Article DOI: 10.1021/jm0205189
BindingDB Entry DOI: 10.7270/Q2WD3ZZ3
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50060452
PNG
((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)
Show SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccccc13)[C@@H](C\C=C/CCCC(O)=O)C2
Show InChI InChI=1S/C25H31NO3S/c1-25(2)17-13-16(9-5-3-4-6-12-22(27)28)23(20(25)14-17)26-24(29)19-15-30-21-11-8-7-10-18(19)21/h3,5,7-8,10-11,15-17,20,23H,4,6,9,12-14H2,1-2H3,(H,26,29)(H,27,28)/b5-3-/t16-,17-,20-,23+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes

J Med Chem 40: 3504-7 (1997)


Article DOI: 10.1021/jm970343g
BindingDB Entry DOI: 10.7270/Q2959GP9
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))		BDBM50128703
PNG
((+) 7-[3-(2-Ethoxy-dibenzofuran-3-sulfonylamino)-b...)
Show SMILES CCOc1cc2c(cc1S(=O)(=O)N[C@@H]1[C@@H]3CC[C@@H](C3)[C@H]1C\C=C/CCCC(O)=O)oc1ccccc21
Show InChI InChI=1S/C28H33NO6S/c1-2-34-25-16-22-21-10-7-8-11-23(21)35-24(22)17-26(25)36(32,33)29-28-19-14-13-18(15-19)20(28)9-5-3-4-6-12-27(30)31/h3,5,7-8,10-11,16-20,28-29H,2,4,6,9,12-15H2,1H3,(H,30,31)/b5-3-/t18-,19+,20+,28+/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membrane

J Med Chem 46: 2436-45 (2003)


Article DOI: 10.1021/jm020517g
BindingDB Entry DOI: 10.7270/Q2154GFS
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 283 total )  |  Next  |  Last  >>
Jump to: