Found 83 hits with Last Name = 'michaux' and Initial = 'j' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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MCE
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| PDB
Article
PubMed
| 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384714
(CHEMBL2037200)Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
MCE
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| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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| PDB
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PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484569
(CHEMBL1934184)Show InChI InChI=1S/C17H9ClN2O2S/c18-15-4-3-14(23-15)16-11-5-6-19-8-12(11)10-2-1-9(17(21)22)7-13(10)20-16/h1-8H,(H,21,22) | PDB
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| PC cid
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UniChem
| Article
PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM152738
(5-(4-chlorophenyl)benzo[c]2,6-naphthyridine-8-carb...)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1ccc(Cl)cc1)c1ccncc21 Show InChI InChI=1S/C19H11ClN2O2/c20-13-4-1-11(2-5-13)18-15-7-8-21-10-16(15)14-6-3-12(19(23)24)9-17(14)22-18/h1-10H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484568
(CHEMBL1934181)Show SMILES CCNc1ncc2c3ccc(cc3nc(-c3ccc(Cl)cc3)c2n1)C(O)=O Show InChI InChI=1S/C20H15ClN4O2/c1-2-22-20-23-10-15-14-8-5-12(19(26)27)9-16(14)24-17(18(15)25-20)11-3-6-13(21)7-4-11/h3-10H,2H2,1H3,(H,26,27)(H,22,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484577
(CHEMBL1934182)Show InChI InChI=1S/C17H10N2O2S/c20-17(21)10-1-2-12-14-8-18-5-3-13(14)16(19-15(12)7-10)11-4-6-22-9-11/h1-9H,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484567
(CHEMBL1934180)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1ccccc1)c1nc(NC3CC3)ncc21 Show InChI InChI=1S/C21H16N4O2/c26-20(27)13-6-9-15-16-11-22-21(23-14-7-8-14)25-19(16)18(24-17(15)10-13)12-4-2-1-3-5-12/h1-6,9-11,14H,7-8H2,(H,26,27)(H,22,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
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| PC cid
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UniChem
| Article
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| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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| PDB
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PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assay |
J Med Chem 54: 635-54 (2011)
Article DOI: 10.1021/jm101251q
BindingDB Entry DOI: 10.7270/Q2J67H7N |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Casein kinase II subunit alpha
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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| PDB
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PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha by radiometric assay |
J Med Chem 54: 635-54 (2011)
Article DOI: 10.1021/jm101251q
BindingDB Entry DOI: 10.7270/Q2J67H7N |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484584
(CHEMBL1934318)Show SMILES OC(=O)c1ccc2c(c1)nc(Sc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H11ClN2O2S/c20-12-2-1-3-13(9-12)25-18-15-6-7-21-10-16(15)14-5-4-11(19(23)24)8-17(14)22-18/h1-10H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
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| PC cid
PC sid
UniChem
| Article
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484579
(CHEMBL1934166)Show InChI InChI=1S/C19H12N2O3/c22-13-3-1-2-11(8-13)18-15-6-7-20-10-16(15)14-5-4-12(19(23)24)9-17(14)21-18/h1-10,22H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484556
(CHEMBL1934160)Show InChI InChI=1S/C19H12N2O2/c22-19(23)13-6-7-14-16-11-20-9-8-15(16)18(21-17(14)10-13)12-4-2-1-3-5-12/h1-11H,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484563
(CHEMBL1934173)Show InChI InChI=1S/C19H11FN2O2/c20-13-4-1-11(2-5-13)18-15-7-8-21-10-16(15)14-6-3-12(19(23)24)9-17(14)22-18/h1-10H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484558
(CHEMBL1934164)Show InChI InChI=1S/C19H11FN2O2/c20-13-3-1-2-11(8-13)18-15-6-7-21-10-16(15)14-5-4-12(19(23)24)9-17(14)22-18/h1-10H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484575
(CHEMBL1934319)Show SMILES OC(=O)c1ccc2c(c1)nc(Cc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C20H13ClN2O2/c21-14-3-1-2-12(8-14)9-18-16-6-7-22-11-17(16)15-5-4-13(20(24)25)10-19(15)23-18/h1-8,10-11H,9H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484559
(CHEMBL1934165)Show InChI InChI=1S/C19H13N3O2/c20-13-3-1-2-11(8-13)18-15-6-7-21-10-16(15)14-5-4-12(19(23)24)9-17(14)22-18/h1-10H,20H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484557
(CHEMBL1934163)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H11ClN2O2/c20-13-3-1-2-11(8-13)18-15-6-7-21-10-16(15)14-5-4-12(19(23)24)9-17(14)22-18/h1-10H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384706
(CHEMBL2037204)Show SMILES CN1CCCN(CC1)C(=O)c1ccc(F)c(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H23ClFN3O3/c1-30-9-2-10-31(12-11-30)26(33)16-3-6-22(28)21(13-16)24-8-5-18(34-24)15-20-19-14-17(27)4-7-23(19)29-25(20)32/h3-8,13-15H,2,9-12H2,1H3,(H,29,32)/b20-15+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484582
(CHEMBL1934178)Show InChI InChI=1S/C18H11N3O3/c22-12-3-1-2-10(6-12)16-17-14(8-19-9-20-17)13-5-4-11(18(23)24)7-15(13)21-16/h1-9,22H,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484562
(CHEMBL1934171)Show SMILES NC(=O)c1cccc(c1)-c1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C20H13N3O3/c21-19(24)12-3-1-2-11(8-12)18-15-6-7-22-10-16(15)14-5-4-13(20(25)26)9-17(14)23-18/h1-10H,(H2,21,24)(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484574
(CHEMBL1934193)Show SMILES OC(=O)c1ccc2c(c1)nc(Oc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H11ClN2O3/c20-12-2-1-3-13(9-12)25-18-15-6-7-21-10-16(15)14-5-4-11(19(23)24)8-17(14)22-18/h1-10H,(H,23,24) | PDB
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| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484583
(CHEMBL1934183)Show InChI InChI=1S/C18H12N2O2S/c1-10-8-23-9-15(10)17-13-4-5-19-7-14(13)12-3-2-11(18(21)22)6-16(12)20-17/h2-9H,1H3,(H,21,22) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384714
(CHEMBL2037200)Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50384706
(CHEMBL2037204)Show SMILES CN1CCCN(CC1)C(=O)c1ccc(F)c(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H23ClFN3O3/c1-30-9-2-10-31(12-11-30)26(33)16-3-6-22(28)21(13-16)24-8-5-18(34-24)15-20-19-14-17(27)4-7-23(19)29-25(20)32/h3-8,13-15H,2,9-12H2,1H3,(H,29,32)/b20-15+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384715
(CHEMBL2037201)Show SMILES Clc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)N3CCCNCC3)c2c1 Show InChI InChI=1S/C25H22ClN3O3/c26-18-5-7-22-20(14-18)21(24(30)28-22)15-19-6-8-23(32-19)16-3-1-4-17(13-16)25(31)29-11-2-9-27-10-12-29/h1,3-8,13-15,27H,2,9-12H2,(H,28,30)/b21-15+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484561
(CHEMBL1934168)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1cccc(OC(F)(F)F)c1)c1ccncc21 Show InChI InChI=1S/C20H11F3N2O3/c21-20(22,23)28-13-3-1-2-11(8-13)18-15-6-7-24-10-16(15)14-5-4-12(19(26)27)9-17(14)25-18/h1-10H,(H,26,27) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484573
(CHEMBL1934192)Show SMILES CN(c1cccc(Cl)c1)c1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C20H14ClN3O2/c1-24(14-4-2-3-13(21)10-14)19-16-7-8-22-11-17(16)15-6-5-12(20(25)26)9-18(15)23-19/h2-11H,1H3,(H,25,26) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484580
(CHEMBL1934170)Show SMILES NS(=O)(=O)c1cccc(c1)-c1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C19H13N3O4S/c20-27(25,26)13-3-1-2-11(8-13)18-15-6-7-21-10-16(15)14-5-4-12(19(23)24)9-17(14)22-18/h1-10H,(H,23,24)(H2,20,25,26) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50335639
(7-((1H-tetrazol-5-yl)methyl)indolo[1,2-a]quinazoli...)Show SMILES O=c1[nH]c2c(Cc3nnn[nH]3)c3ccccc3n2c2ccccc12 Show InChI InChI=1S/C17H12N6O/c24-17-11-6-2-4-8-14(11)23-13-7-3-1-5-10(13)12(16(23)18-17)9-15-19-21-22-20-15/h1-8H,9H2,(H,18,24)(H,19,20,21,22) | PDB
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Cylene Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of PARP1 at 1 uM by chemiluminescence assay |
J Med Chem 54: 635-54 (2011)
Article DOI: 10.1021/jm101251q
BindingDB Entry DOI: 10.7270/Q2J67H7N |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484565
(CHEMBL1934177)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1ccc(Cl)cc1)c1ncncc21 Show InChI InChI=1S/C18H10ClN3O2/c19-12-4-1-10(2-5-12)16-17-14(8-20-9-21-17)13-6-3-11(18(23)24)7-15(13)22-16/h1-9H,(H,23,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484576
(CHEMBL1934169)Show SMILES CS(=O)(=O)c1cccc(c1)-c1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C20H14N2O4S/c1-27(25,26)14-4-2-3-12(9-14)19-16-7-8-21-11-17(16)15-6-5-13(20(23)24)10-18(15)22-19/h2-11H,1H3,(H,23,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484564
(CHEMBL1934176)Show InChI InChI=1S/C19H11FN2O2/c20-16-4-2-1-3-14(16)18-13-7-8-21-10-15(13)12-6-5-11(19(23)24)9-17(12)22-18/h1-10H,(H,23,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human)) | BDBM50384714
(CHEMBL2037200)Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+ | KEGG
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| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Pim3 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484566
(CHEMBL1934179)Show SMILES NC(=O)c1cccc(c1)-c1nc2cc(ccc2c2cncnc12)C(O)=O Show InChI InChI=1S/C19H12N4O3/c20-18(24)11-3-1-2-10(6-11)16-17-14(8-21-9-22-17)13-5-4-12(19(25)26)7-15(13)23-16/h1-9H,(H2,20,24)(H,25,26) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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Cylene Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant DAPK3 by radiometric assay |
J Med Chem 54: 635-54 (2011)
Article DOI: 10.1021/jm101251q
BindingDB Entry DOI: 10.7270/Q2J67H7N |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484587
(CHEMBL1934189)Show SMILES Clc1ccc(cc1)-c1nc2cc(ccc2c2cnccc12)-c1nnn[nH]1 Show InChI InChI=1S/C19H11ClN6/c20-13-4-1-11(2-5-13)18-15-7-8-21-10-16(15)14-6-3-12(9-17(14)22-18)19-23-25-26-24-19/h1-10H,(H,23,24,25,26) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484586
(CHEMBL1934174)Show InChI InChI=1S/C20H14N2O2/c1-12-4-2-3-5-14(12)19-16-8-9-21-11-17(16)15-7-6-13(20(23)24)10-18(15)22-19/h2-11H,1H3,(H,23,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384717
(CHEMBL2037203)Show SMILES CN1CCCN(CC1)C(=O)c1ccc(Cl)c(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H23Cl2N3O3/c1-30-9-2-10-31(12-11-30)26(33)16-3-6-22(28)21(13-16)24-8-5-18(34-24)15-20-19-14-17(27)4-7-23(19)29-25(20)32/h3-8,13-15H,2,9-12H2,1H3,(H,29,32)/b20-15+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384709
(CHEMBL2037195)Show SMILES Clc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)NCCN3CCCC3)c2c1 Show InChI InChI=1S/C26H24ClN3O3/c27-19-6-8-23-21(15-19)22(26(32)29-23)16-20-7-9-24(33-20)17-4-3-5-18(14-17)25(31)28-10-13-30-11-1-2-12-30/h3-9,14-16H,1-2,10-13H2,(H,28,31)(H,29,32)/b22-16+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50384715
(CHEMBL2037201)Show SMILES Clc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)N3CCCNCC3)c2c1 Show InChI InChI=1S/C25H22ClN3O3/c26-18-5-7-22-20(14-18)21(24(30)28-22)15-19-6-8-23(32-19)16-3-1-4-17(13-16)25(31)29-11-2-9-27-10-12-29/h1,3-8,13-15,27H,2,9-12H2,(H,28,30)/b21-15+ | PDB
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| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50384713
(CHEMBL2037199)Show SMILES OCCCNC(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C23H19ClN2O4/c24-16-5-7-20-18(12-16)19(23(29)26-20)13-17-6-8-21(30-17)14-3-1-4-15(11-14)22(28)25-9-2-10-27/h1,3-8,11-13,27H,2,9-10H2,(H,25,28)(H,26,29)/b19-13+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50384714
(CHEMBL2037200)Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM152739
(5-(4-chlorophenyl)benzo[c]2,6-naphthyridine-8-carb...)Show SMILES NC(=O)c1ccc2c(c1)nc(-c1ccc(Cl)cc1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O/c20-13-4-1-11(2-5-13)18-15-7-8-22-10-16(15)14-6-3-12(19(21)24)9-17(14)23-18/h1-10H,(H2,21,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484560
(CHEMBL1934167)Show InChI InChI=1S/C20H14N2O3/c1-25-14-4-2-3-12(9-14)19-16-7-8-21-11-17(16)15-6-5-13(20(23)24)10-18(15)22-19/h2-11H,1H3,(H,23,24) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484585
(CHEMBL1934162)Show InChI InChI=1S/C18H11N3O2/c22-18(23)12-1-2-13-15-10-20-8-5-14(15)17(21-16(13)9-12)11-3-6-19-7-4-11/h1-10H,(H,22,23) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human)) | BDBM50335638
(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) | PDB
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Cylene Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant TBK1 by radiometric assay |
J Med Chem 54: 635-54 (2011)
Article DOI: 10.1021/jm101251q
BindingDB Entry DOI: 10.7270/Q2J67H7N |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50384718
(CHEMBL2037205)Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(o1)C(C)=C1C(=O)Nc2ccc(Cl)cc12 Show InChI InChI=1S/C27H26ClN3O3/c1-17(25-21-16-20(28)7-8-22(21)29-26(25)32)23-9-10-24(34-23)18-5-3-6-19(15-18)27(33)31-12-4-11-30(2)13-14-31/h3,5-10,15-16H,4,11-14H2,1-2H3,(H,29,32) | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human)) | BDBM50384713
(CHEMBL2037199)Show SMILES OCCCNC(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C23H19ClN2O4/c24-16-5-7-20-18(12-16)19(23(29)26-20)13-17-6-8-21(30-17)14-3-1-4-15(11-14)22(28)25-9-2-10-27/h1,3-8,11-13,27H,2,9-10H2,(H,25,28)(H,26,29)/b19-13+ | PDB
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay |
ACS Med Chem Lett 3: 135-139 (2012)
Article DOI: 10.1021/ml200259q
BindingDB Entry DOI: 10.7270/Q2X92CBW |
More data for this
Ligand-Target Pair | |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50484581
(CHEMBL1934175)Show SMILES OC(=O)c1ccc2c(c1)nc(-c1ccccc1OC(F)(F)F)c1ccncc21 Show InChI InChI=1S/C20H11F3N2O3/c21-20(22,23)28-17-4-2-1-3-14(17)18-13-7-8-24-10-15(13)12-6-5-11(19(26)27)9-16(12)25-18/h1-10H,(H,26,27) | PDB
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Cylene Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assay |
Bioorg Med Chem Lett 22: 45-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.087
BindingDB Entry DOI: 10.7270/Q24Q7XV4 |
More data for this
Ligand-Target Pair | |
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