Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Rattus norvegicus (rat)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10843 (4-(5,6-dibromo-1H-indol-3-yl)pyrimidin-2-amine | M...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Rattus norvegicus (rat)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10838 (3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10839 (3-(2-aminopyrimidin-4-yl)-6-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10843 (4-(5,6-dibromo-1H-indol-3-yl)pyrimidin-2-amine | M...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10842 (3-(2-aminopyrimidin-4-yl)-7-bromo-1H-indol-4-ol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10838 (3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10838 (3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10843 (4-(5,6-dibromo-1H-indol-3-yl)pyrimidin-2-amine | M...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10838 (3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Rattus norvegicus (rat)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10843 (4-(5,6-dibromo-1H-indol-3-yl)pyrimidin-2-amine | M...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10843 (4-(5,6-dibromo-1H-indol-3-yl)pyrimidin-2-amine | M...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Rattus norvegicus (rat)) | BDBM10840 (4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Rattus norvegicus (rat)) | BDBM10841 (4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine | Merid...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10844 (4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10846 (4-(1H-indol-2-yl)pyrimidin-2-amine | isomeridianin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10846 (4-(1H-indol-2-yl)pyrimidin-2-amine | isomeridianin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10844 (4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10844 (4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM10845 (4-(5-bromo-1H-indol-2-yl)pyrimidin-2-amine | isome...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10838 (3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human)) | BDBM10845 (4-(5-bromo-1H-indol-2-yl)pyrimidin-2-amine | isome...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10844 (4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM10844 (4-(1H-indol-3-yl)pyrimidin-2-amine | Meridianin G) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat)) | BDBM10846 (4-(1H-indol-2-yl)pyrimidin-2-amine | isomeridianin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM10846 (4-(1H-indol-2-yl)pyrimidin-2-amine | isomeridianin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM7533 ((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | 30 |
CNRS | Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30°C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P ... | Bioorg Med Chem Lett 14: 1703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.050 BindingDB Entry DOI: 10.7270/Q2BZ648W | |||||||||||
More data for this Ligand-Target Pair |
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