BindingDB PrimarySearch

Found 40 hits with Last Name = 'wells' and Initial = 'ja'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bcl2-associated agonist of cell death (Homo sapiens (Human))	BDBM21447 (4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to Bcl-XL assessed as inhibition of Bcl-XL-BAD derived peptide interaction				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50229786 (5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-P...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to IL2 assessed as inhibition of IL2-IL2Ralpha interaction				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50526692 (CHEMBL1230881) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of wild-type human CHK1 (1 to 289 residues) expressed in baculovirus infected Sf21 insect cells preincubated for 15 mins followed by ATP a...				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein ZipA (Escherichia coli (strain K12))	BDBM50162319 (2-(4-(4-(2-(3-chloro-4-methylphenylamino)pyrimidin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to Escherichia coli ZipA assessed as inhibition of ZipA-FtsZ derived peptide interaction				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453891 (CHEMBL4214567) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human EGFR L858R/T790M mutant (696 to 1022 residues) expressed in Sf9 insect cells by HTRF assay				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bcl2-associated agonist of cell death (Homo sapiens (Human))	BDBM50373072 (CHEMBL402005) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to Bcl-XL				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50229787 ((4S,5R)-Nutlin-3 \| (rac)-(4,5-bis(4-chlorophenyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to human HDM2 assessed as inhibition of HDM2-p53 interaction				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50325999 (3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of wild-type BCR-ABL (unknown origin) expressed in mouse Ba/F3 cells as cell growth inhibition after 48 hrs by MTT assay				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50526695 (BI-78D3 \| CHEMBL508280) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assay				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31285 (BMCL163310 Compound 1 \| CHEMBL361103 \| benzodiazep...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to human HDM2				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50431630 (KRX-0401 \| PERIFOSINE) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cells				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50526693 (CHEMBL4445946) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cells				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50526696 (CHEMBL4459106) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cells				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50379277 (CHEMBL90825) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem	MMDB Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of C-terminal His6-tagged human JNK1alpha1 (1 to 364 residues) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in MKK7...				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM50326058 (CHEMBL1242213 \| N-(3-(imidazo[1,2-a]pyridin-2-yl)p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mature Caspase3				Nat Chem Biol 6: 179-188 (2010) Article DOI: 10.1038/nchembio.318 BindingDB Entry DOI: 10.7270/Q25Q4W9Q
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125816 (CHEMBL1439113) Show SMILES Cc1cccc(C)c1OCCSc1nc2ccccc2n1CC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125790 (CHEMBL3623846) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.94E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125817 (CHEMBL3623845) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125791 (CHEMBL3623844) Show SMILES Cc1ccc(OCCSc2nc3ccccc3n2CC(O)=O)c(C)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125816 (CHEMBL1439113) Show SMILES Cc1cccc(C)c1OCCSc1nc2ccccc2n1CC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Activation of human PDK1 catalytic activity using PIFtide as substrate after 1 hr by phosphor imager analysis in presence of [gamma-32P]-ATP relative...				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tumor necrosis factor (Homo sapiens (Human))	BDBM50373071 (CHEMBL255489) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to TNF				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein ZipA (Escherichia coli (strain K12))	BDBM50162321 (CHEMBL369180 \| N-METHYL-N-[3-(6-PHENYL[1,2,4]TRIAZ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	8.31E+4	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to Escherichia coli ZipA				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM31285 (BMCL163310 Compound 1 \| CHEMBL361103 \| benzodiazep...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco Curated by ChEMBL					Assay Description Binding affinity to human HDM2				Nature 450: 1001-1009 (2007) Article DOI: 10.1038/nature06526 BindingDB Entry DOI: 10.7270/Q24Q7VTV
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50526694 (CHEMBL4592040) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of fluorescent PIFtide from PDK1 (50 to 359 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for ...				J Med Chem 62: 6512-6524 (2019) Article DOI: 10.1021/acs.jmedchem.9b00089 BindingDB Entry DOI: 10.7270/Q25X2DC4
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM56130 (2-[2-(2-phenoxyethylsulfanyl)benzimidazol-1-yl]ace...) Show SMILES OC(=O)Cn1c(SCCOc2ccccc2)nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125815 (CHEMBL2139600) Show SMILES COc1ccccc1OCCSc1nc2ccccc2n1CC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125813 (CHEMBL1310463) Show SMILES OC(=O)Cn1c(SCCOc2ccccc2F)nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125812 (CHEMBL3623847) Show SMILES Cc1ccccc1OCCSc1nc2ccccc2n1CC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125810 (CHEMBL3623848) Show SMILES Cc1cccc(OCCSc2nc3ccccc3n2CC(O)=O)c1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125807 (CHEMBL1382642) Show SMILES Cc1ccccc1OCCSc1nc2ccccc2n1CCC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50387244 (CHEMBL1549031) Show SMILES OC(=O)Cn1c(SCc2ccccc2)nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125804 (CHEMBL1568528) Show SMILES OC(=O)Cn1c(SCc2cccc3ccccc23)nc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125800 (CHEMBL3623849) Show SMILES OC(=O)CSc1nc2ccccc2n1CCOc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125798 (CHEMBL1559959) Show SMILES Cc1cccc(OCCn2c(SCC(O)=O)nc3ccccc23)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125797 (CHEMBL3623850) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125795 (CHEMBL3623851) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125794 (CHEMBL3623852) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125792 (CHEMBL3623853) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Displacement of PIFtide from human PDK1 PIF pocket after 1 hr by fluorescence polarization assay				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125790 (CHEMBL3623846) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Activation of human PDK1 catalytic activity using PIFtide as substrate after 1 hr by phosphor imager analysis in presence of [gamma-32P]-ATP relative...				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50125791 (CHEMBL3623844) Show SMILES Cc1ccc(OCCSc2nc3ccccc3n2CC(O)=O)c(C)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a
Bioinformatics Institute (BII) Curated by ChEMBL					Assay Description Activation of human PDK1 catalytic activity using PIFtide as substrate after 1 hr by phosphor imager analysis in presence of [gamma-32P]-ATP relative...				J Med Chem 58: 8285-91 (2015) Article DOI: 10.1021/acs.jmedchem.5b01216 BindingDB Entry DOI: 10.7270/Q2NS0WR2
Bioinformatics Institute (BII) Curated by ChEMBL					More data for this Ligand-Target Pair