Compile Data Set for Download or QSAR

Found 79 hits with Last Name = 'buynitsky' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083766 (2-(3,5-Dichloro-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccccc1 |t:8| Show InChI InChI=1S/C26H28Cl2N6O6S/c27-19-12-17(16-6-2-1-3-7-16)13-20(28)23(19)41(38,39)34-22(25(36)37)15-32-24(35)21-14-18(40-33-21)8-4-5-9-29-26-30-10-11-31-26/h1-3,6-7,10-13,18,22,34H,4-5,8-9,14-15H2,(H,32,35)(H,36,37)(H2,29,30,31)/t18?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083788 (2-(2-Chloro-6-methyl-benzenesulfonylamino)-3-({5-[...) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:18| Show InChI InChI=1S/C21H27ClN6O6S/c1-13-5-4-7-15(22)18(13)35(32,33)28-17(20(30)31)12-26-19(29)16-11-14(34-27-16)6-2-3-8-23-21-24-9-10-25-21/h4-5,7,9-10,14,17,28H,2-3,6,8,11-12H2,1H3,(H,26,29)(H,30,31)(H2,23,24,25)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083789 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C28H34N6O6S/c1-18-14-21(20-8-4-3-5-9-20)15-19(2)25(18)41(38,39)34-24(27(36)37)17-32-26(35)23-16-22(40-33-23)10-6-7-11-29-28-30-12-13-31-28/h3-5,8-9,12-15,22,24,34H,6-7,10-11,16-17H2,1-2H3,(H,32,35)(H,36,37)(H2,29,30,31)/t22?,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083769 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H32N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h8-11,17,19,29H,4-7,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083783 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({5-[4-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cccc1Cl |t:8| Show InChI InChI=1S/C20H24Cl2N6O6S/c21-13-5-3-6-14(22)17(13)35(32,33)28-16(19(30)31)11-26-18(29)15-10-12(34-27-15)4-1-2-7-23-20-24-8-9-25-20/h3,5-6,8-9,12,16,28H,1-2,4,7,10-11H2,(H,26,29)(H,30,31)(H2,23,24,25)/t12?,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083791 (3-({5-[3-(6-Amino-pyridin-2-yl)-propyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cccc(N)n2)C1)C(O)=O |t:19| Show InChI InChI=1S/C24H31N5O6S/c1-14-10-15(2)22(16(3)11-14)36(33,34)29-20(24(31)32)13-26-23(30)19-12-18(35-28-19)8-4-6-17-7-5-9-21(25)27-17/h5,7,9-11,18,20,29H,4,6,8,12-13H2,1-3H3,(H2,25,27)(H,26,30)(H,31,32)/t18?,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083785 (3-({5-[3-(1H-Imidazol-2-ylcarbamoyl)-propyl]-4,5-d...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCC(=O)Nc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H30N6O7S/c1-13-9-14(2)20(15(3)10-13)37(34,35)29-18(22(32)33)12-26-21(31)17-11-16(36-28-17)5-4-6-19(30)27-23-24-7-8-25-23/h7-10,16,18,29H,4-6,11-12H2,1-3H3,(H,26,31)(H,32,33)(H2,24,25,27,30)/t16?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083775 (3-[(5-{2-[3-(1H-Imidazol-2-yl)-ureido]-ethyl}-4,5-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCNC(=O)Nc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H29N7O7S/c1-12-8-13(2)18(14(3)9-12)37(34,35)29-17(20(31)32)11-26-19(30)16-10-15(36-28-16)4-5-25-22(33)27-21-23-6-7-24-21/h6-9,15,17,29H,4-5,10-11H2,1-3H3,(H,26,30)(H,31,32)(H3,23,24,25,27,33)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083780 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C30H35N5O6S/c1-20-16-23(22-10-4-3-5-11-22)17-21(2)28(20)42(39,40)35-26(30(37)38)19-33-29(36)25-18-24(41-34-25)12-6-8-14-31-27-13-7-9-15-32-27/h3-5,7,9-11,13,15-17,24,26,35H,6,8,12,14,18-19H2,1-2H3,(H,31,32)(H,33,36)(H,37,38)/t24?,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083770 (3-({5-[3-(2-Amino-1H-imidazol-4-yl)-propyl]-4,5-di...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cnc(N)[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H30N6O6S/c1-12-7-13(2)19(14(3)8-12)35(32,33)28-18(21(30)31)11-24-20(29)17-9-16(34-27-17)6-4-5-15-10-25-22(23)26-15/h7-8,10,16,18,28H,4-6,9,11H2,1-3H3,(H,24,29)(H,30,31)(H3,23,25,26)/t16?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083767 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1cccc2ccccc12 |t:8| Show InChI InChI=1S/C24H28N6O6S/c31-22(19-14-17(36-29-19)8-3-4-11-25-24-26-12-13-27-24)28-15-20(23(32)33)30-37(34,35)21-10-5-7-16-6-1-2-9-18(16)21/h1-2,5-7,9-10,12-13,17,20,30H,3-4,8,11,14-15H2,(H,28,31)(H,32,33)(H2,25,26,27)/t17?,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083781 (3-({5-[4-(Pyridin-2-ylamino)-butyl]-4,5-dihydro-is...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O |t:19| Show InChI InChI=1S/C25H33N5O6S/c1-16-12-17(2)23(18(3)13-16)37(34,35)30-21(25(32)33)15-28-24(31)20-14-19(36-29-20)8-4-6-10-26-22-9-5-7-11-27-22/h5,7,9,11-13,19,21,30H,4,6,8,10,14-15H2,1-3H3,(H,26,27)(H,28,31)(H,32,33)/t19?,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083774 (3-({5-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyl...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC2=NCCN2)C1)C(O)=O |t:19,28| Show InChI InChI=1S/C23H34N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h10-11,17,19,29H,4-9,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083771 (2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-({5-[...) Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:17| Show InChI InChI=1S/C19H27N7O7S/c1-11-16(12(2)32-24-11)34(30,31)26-15(18(28)29)10-23-17(27)14-9-13(33-25-14)5-3-4-6-20-19-21-7-8-22-19/h7-8,13,15,26H,3-6,9-10H2,1-2H3,(H,23,27)(H,28,29)(H2,20,21,22)/t13?,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083786 (2-Benzenesulfonylamino-3-({5-[4-(pyridin-2-ylamino...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C22H27N5O6S/c28-21(25-15-19(22(29)30)27-34(31,32)17-9-2-1-3-10-17)18-14-16(33-26-18)8-4-6-12-23-20-11-5-7-13-24-20/h1-3,5,7,9-11,13,16,19,27H,4,6,8,12,14-15H2,(H,23,24)(H,25,28)(H,29,30)/t16?,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083765 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H28N6O6S/c1-12-8-13(2)18(14(3)9-12)34(31,32)27-17(20(29)30)11-25-19(28)16-10-15(33-26-16)4-5-22-21-23-6-7-24-21/h6-9,15,17,27H,4-5,10-11H2,1-3H3,(H,25,28)(H,29,30)(H2,22,23,24)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083773 (2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(pyridin-2-y...) Show SMILES CN([C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |t:7| Show InChI InChI=1S/C29H33N5O6S/c1-34(41(38,39)24-15-13-22(14-16-24)21-9-3-2-4-10-21)26(29(36)37)20-32-28(35)25-19-23(40-33-25)11-5-7-17-30-27-12-6-8-18-31-27/h2-4,6,8-10,12-16,18,23,26H,5,7,11,17,19-20H2,1H3,(H,30,31)(H,32,35)(H,36,37)/t23?,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50055900 (3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...) Show SMILES NC(=N)c1ccc(cc1)C1=NO[C@@H](CC(=O)NCCC(O)=O)C1 |t:10| Show InChI InChI=1S/C15H18N4O4/c16-15(17)10-3-1-9(2-4-10)12-7-11(23-19-12)8-13(20)18-6-5-14(21)22/h1-4,11H,5-8H2,(H3,16,17)(H,18,20)(H,21,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083784 (2-(Naphthalene-1-sulfonylamino)-3-({5-[4-(pyridin-...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)NS(=O)(=O)c1cccc2ccccc12 |t:8| Show InChI InChI=1S/C26H29N5O6S/c32-25(21-16-19(37-30-21)10-3-5-14-27-24-13-4-6-15-28-24)29-17-22(26(33)34)31-38(35,36)23-12-7-9-18-8-1-2-11-20(18)23/h1-2,4,6-9,11-13,15,19,22,31H,3,5,10,14,16-17H2,(H,27,28)(H,29,32)(H,33,34)/t19?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50076575 (3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC(N)=N)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H32N6O6S/c1-12-8-13(2)18(14(3)9-12)34(31,32)27-17(20(29)30)11-25-19(28)16-10-15(33-26-16)6-4-5-7-24-21(22)23/h8-9,15,17,27H,4-7,10-11H2,1-3H3,(H,25,28)(H,29,30)(H4,22,23,24)/t15?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50076575 (3-{5-[4-amino(imino)methylaminobutyl]-4,5-dihydro-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC(N)=N)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H32N6O6S/c1-12-8-13(2)18(14(3)9-12)34(31,32)27-17(20(29)30)11-25-19(28)16-10-15(33-26-16)6-4-5-7-24-21(22)23/h8-9,15,17,27H,4-7,10-11H2,1-3H3,(H,25,28)(H,29,30)(H4,22,23,24)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083792 (2-(4-Isopropyl-benzenesulfonylamino)-3-({5-[4-(pyr...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O |t:19| Show InChI InChI=1S/C25H33N5O6S/c1-17(2)18-9-11-20(12-10-18)37(34,35)30-22(25(32)33)16-28-24(31)21-15-19(36-29-21)7-3-5-13-26-23-8-4-6-14-27-23/h4,6,8-12,14,17,19,22,30H,3,5,7,13,15-16H2,1-2H3,(H,26,27)(H,28,31)(H,32,33)/t19?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083770 (3-({5-[3-(2-Amino-1H-imidazol-4-yl)-propyl]-4,5-di...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cnc(N)[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H30N6O6S/c1-12-7-13(2)19(14(3)8-12)35(32,33)28-18(21(30)31)11-24-20(29)17-9-16(34-27-17)6-4-5-15-10-25-22(23)26-15/h7-8,10,16,18,28H,4-6,9,11H2,1-3H3,(H,24,29)(H,30,31)(H3,23,25,26)/t16?,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083783 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({5-[4-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cccc1Cl |t:8| Show InChI InChI=1S/C20H24Cl2N6O6S/c21-13-5-3-6-14(22)17(13)35(32,33)28-16(19(30)31)11-26-18(29)15-10-12(34-27-15)4-1-2-7-23-20-24-8-9-25-20/h3,5-6,8-9,12,16,28H,1-2,4,7,10-11H2,(H,26,29)(H,30,31)(H2,23,24,25)/t12?,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083778 (2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(1H-imidazol...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1 |t:8| Show InChI InChI=1S/C26H30N6O6S/c33-24(22-16-20(38-31-22)8-4-5-13-27-26-28-14-15-29-26)30-17-23(25(34)35)32-39(36,37)21-11-9-19(10-12-21)18-6-2-1-3-7-18/h1-3,6-7,9-12,14-15,20,23,32H,4-5,8,13,16-17H2,(H,30,33)(H,34,35)(H2,27,28,29)/t20?,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50055900 (3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...) Show SMILES NC(=N)c1ccc(cc1)C1=NO[C@@H](CC(=O)NCCC(O)=O)C1 |t:10| Show InChI InChI=1S/C15H18N4O4/c16-15(17)10-3-1-9(2-4-10)12-7-11(23-19-12)8-13(20)18-6-5-14(21)22/h1-4,11H,5-8H2,(H3,16,17)(H,18,20)(H,21,22)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083770 (3-({5-[3-(2-Amino-1H-imidazol-4-yl)-propyl]-4,5-di...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cnc(N)[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H30N6O6S/c1-12-7-13(2)19(14(3)8-12)35(32,33)28-18(21(30)31)11-24-20(29)17-9-16(34-27-17)6-4-5-15-10-25-22(23)26-15/h7-8,10,16,18,28H,4-6,9,11H2,1-3H3,(H,24,29)(H,30,31)(H3,23,25,26)/t16?,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083783 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({5-[4-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cccc1Cl |t:8| Show InChI InChI=1S/C20H24Cl2N6O6S/c21-13-5-3-6-14(22)17(13)35(32,33)28-16(19(30)31)11-26-18(29)15-10-12(34-27-15)4-1-2-7-23-20-24-8-9-25-20/h3,5-6,8-9,12,16,28H,1-2,4,7,10-11H2,(H,26,29)(H,30,31)(H2,23,24,25)/t12?,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083788 (2-(2-Chloro-6-methyl-benzenesulfonylamino)-3-({5-[...) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:18| Show InChI InChI=1S/C21H27ClN6O6S/c1-13-5-4-7-15(22)18(13)35(32,33)28-17(20(30)31)12-26-19(29)16-11-14(34-27-16)6-2-3-8-23-21-24-9-10-25-21/h4-5,7,9-10,14,17,28H,2-3,6,8,11-12H2,1H3,(H,26,29)(H,30,31)(H2,23,24,25)/t14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083767 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1cccc2ccccc12 |t:8| Show InChI InChI=1S/C24H28N6O6S/c31-22(19-14-17(36-29-19)8-3-4-11-25-24-26-12-13-27-24)28-15-20(23(32)33)30-37(34,35)21-10-5-7-16-6-1-2-9-18(16)21/h1-2,5-7,9-10,12-13,17,20,30H,3-4,8,11,14-15H2,(H,28,31)(H,32,33)(H2,25,26,27)/t17?,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083774 (3-({5-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyl...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC2=NCCN2)C1)C(O)=O |t:19,28| Show InChI InChI=1S/C23H34N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h10-11,17,19,29H,4-9,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083774 (3-({5-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyl...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC2=NCCN2)C1)C(O)=O |t:19,28| Show InChI InChI=1S/C23H34N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h10-11,17,19,29H,4-9,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083789 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C28H34N6O6S/c1-18-14-21(20-8-4-3-5-9-20)15-19(2)25(18)41(38,39)34-24(27(36)37)17-32-26(35)23-16-22(40-33-23)10-6-7-11-29-28-30-12-13-31-28/h3-5,8-9,12-15,22,24,34H,6-7,10-11,16-17H2,1-2H3,(H,32,35)(H,36,37)(H2,29,30,31)/t22?,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083769 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H32N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h8-11,17,19,29H,4-7,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083787 (2-Amino-3-({5-[4-(1H-imidazol-2-ylamino)-butyl]-4,...) Show SMILES N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:6| Show InChI InChI=1S/C14H22N6O4/c15-10(13(22)23)8-19-12(21)11-7-9(24-20-11)3-1-2-4-16-14-17-5-6-18-14/h5-6,9-10H,1-4,7-8,15H2,(H,19,21)(H,22,23)(H2,16,17,18)/t9?,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083779 (3-({5-[4-(Isoquinolin-1-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2nccc3ccccc23)C1)C(O)=O |t:19| Show InChI InChI=1S/C29H35N5O6S/c1-18-14-19(2)26(20(3)15-18)41(38,39)34-25(29(36)37)17-32-28(35)24-16-22(40-33-24)9-6-7-12-30-27-23-10-5-4-8-21(23)11-13-31-27/h4-5,8,10-11,13-15,22,25,34H,6-7,9,12,16-17H2,1-3H3,(H,30,31)(H,32,35)(H,36,37)/t22?,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083782 (2-[2,4,6-trimethylphenylsulfonylamino]-3-[5-(4-ami...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNS(N)(=O)=O)C1)C(O)=O |t:19| Show InChI InChI=1S/C20H31N5O8S2/c1-12-8-13(2)18(14(3)9-12)34(29,30)25-17(20(27)28)11-22-19(26)16-10-15(33-24-16)6-4-5-7-23-35(21,31)32/h8-9,15,17,23,25H,4-7,10-11H2,1-3H3,(H,22,26)(H,27,28)(H2,21,31,32)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083790 (2-(2,4,6-Trimethyl-benzenesulfonylamino)-3-{[5-(4-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNC(N)=O)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H31N5O7S/c1-12-8-13(2)18(14(3)9-12)34(31,32)26-17(20(28)29)11-24-19(27)16-10-15(33-25-16)6-4-5-7-23-21(22)30/h8-9,15,17,26H,4-7,10-11H2,1-3H3,(H,24,27)(H,28,29)(H3,22,23,30)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083777 (3-({5-[4-(Isoquinolin-3-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2cc3ccccc3cn2)C1)C(O)=O |t:19| Show InChI InChI=1S/C29H35N5O6S/c1-18-12-19(2)27(20(3)13-18)41(38,39)34-25(29(36)37)17-32-28(35)24-15-23(40-33-24)10-6-7-11-30-26-14-21-8-4-5-9-22(21)16-31-26/h4-5,8-9,12-14,16,23,25,34H,6-7,10-11,15,17H2,1-3H3,(H,30,31)(H,32,35)(H,36,37)/t23?,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083771 (2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-({5-[...) Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:17| Show InChI InChI=1S/C19H27N7O7S/c1-11-16(12(2)32-24-11)34(30,31)26-15(18(28)29)10-23-17(27)14-9-13(33-25-14)5-3-4-6-20-19-21-7-8-22-19/h7-8,13,15,26H,3-6,9-10H2,1-2H3,(H,23,27)(H,28,29)(H2,20,21,22)/t13?,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083766 (2-(3,5-Dichloro-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccccc1 |t:8| Show InChI InChI=1S/C26H28Cl2N6O6S/c27-19-12-17(16-6-2-1-3-7-16)13-20(28)23(19)41(38,39)34-22(25(36)37)15-32-24(35)21-14-18(40-33-21)8-4-5-9-29-26-30-10-11-31-26/h1-3,6-7,10-13,18,22,34H,4-5,8-9,14-15H2,(H,32,35)(H,36,37)(H2,29,30,31)/t18?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50408869 (CHEMBL2111850) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H32N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h8-11,17,19,29H,4-7,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083765 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H28N6O6S/c1-12-8-13(2)18(14(3)9-12)34(31,32)27-17(20(29)30)11-25-19(28)16-10-15(33-26-16)4-5-22-21-23-6-7-24-21/h6-9,15,17,27H,4-5,10-11H2,1-3H3,(H,25,28)(H,29,30)(H2,22,23,24)/t15?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083789 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C28H34N6O6S/c1-18-14-21(20-8-4-3-5-9-20)15-19(2)25(18)41(38,39)34-24(27(36)37)17-32-26(35)23-16-22(40-33-23)10-6-7-11-29-28-30-12-13-31-28/h3-5,8-9,12-15,22,24,34H,6-7,10-11,16-17H2,1-2H3,(H,32,35)(H,36,37)(H2,29,30,31)/t22?,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083765 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C21H28N6O6S/c1-12-8-13(2)18(14(3)9-12)34(31,32)27-17(20(29)30)11-25-19(28)16-10-15(33-26-16)4-5-22-21-23-6-7-24-21/h6-9,15,17,27H,4-5,10-11H2,1-3H3,(H,25,28)(H,29,30)(H2,22,23,24)/t15?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of platelet aggregation in human platelet rich plasma (PRP)				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair

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