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Compile Data Set for Download or QSAR

Found 195 hits with Last Name = 'bhat' and Initial = 'l'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 0.190n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.300n/a 0.980n/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...

US Patent US9604944 (2017)


BindingDB Entry DOI: 10.7270/Q2ZW1NZ2
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.300n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Dopamine, D2s: Radioligand: [3H]Spiperone (20-60 Ci/mmol) or [3H]-7-hydroxy DPAT, 1.0 nMControl Compound: Haloperidol or ChlorpromazineIncubation Con...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.300n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) C...

J Med Chem 52: 2226-32 (2009)


BindingDB Entry DOI: 10.7270/Q2QZ2D9J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 0.610n/a 1.96n/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...

US Patent US9604944 (2017)


BindingDB Entry DOI: 10.7270/Q2ZW1NZ2
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 0.610n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) C...

J Med Chem 52: 2226-32 (2009)


BindingDB Entry DOI: 10.7270/Q2QZ2D9J
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 0.620n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Dopamine, D2s: Radioligand: [3H]Spiperone (20-60 Ci/mmol) or [3H]-7-hydroxy DPAT, 1.0 nMControl Compound: Haloperidol or ChlorpromazineIncubation Con...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.650n/a 0.970n/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...

US Patent US9604944 (2017)


BindingDB Entry DOI: 10.7270/Q2ZW1NZ2
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.650n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312156
PNG
(6-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-2H...)
Show SMILES COc1ccccc1N1CCN(CCCCOc2ccc3OCC(=O)Nc3c2)CC1
Show InChI InChI=1S/C23H29N3O4/c1-28-22-7-3-2-6-20(22)26-13-11-25(12-14-26)10-4-5-15-29-18-8-9-21-19(16-18)24-23(27)17-30-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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 0.650n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...

J Med Chem 52: 2226-32 (2009)


BindingDB Entry DOI: 10.7270/Q2QZ2D9J
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202585
PNG
(US10035761, Compound 8j | US9238625, 8j)
Show SMILES CCOCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-25-13-6-5-12-24-20(14-16(2)3)21(10-7-11-21)17-8-9-18(22)19(23)15-17/h8-9,15-16,20,24H,4-7,10-14H2,1-3H3/t20-/m1/s1
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 0.800n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202585
PNG
(US10035761, Compound 8j | US9238625, 8j)
Show SMILES CCOCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-25-13-6-5-12-24-20(14-16(2)3)21(10-7-11-21)17-8-9-18(22)19(23)15-17/h8-9,15-16,20,24H,4-7,10-14H2,1-3H3/t20-/m1/s1
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 0.800n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM172726
PNG
(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1
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 0.910n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM172726
PNG
(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1
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 0.910n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172721
PNG
(US9096515, 21a | US9296681, 21a)
Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H30Cl2N2O2/c1-4-26-19(25)24-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3,(H,24,25)
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 1n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM172721
PNG
(US9096515, 21a | US9296681, 21a)
Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H30Cl2N2O2/c1-4-26-19(25)24-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3,(H,24,25)
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 1n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202585
PNG
(US10035761, Compound 8j | US9238625, 8j)
Show SMILES CCOCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-25-13-6-5-12-24-20(14-16(2)3)21(10-7-11-21)17-8-9-18(22)19(23)15-17/h8-9,15-16,20,24H,4-7,10-14H2,1-3H3/t20-/m1/s1
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 1.16n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202585
PNG
(US10035761, Compound 8j | US9238625, 8j)
Show SMILES CCOCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-25-13-6-5-12-24-20(14-16(2)3)21(10-7-11-21)17-8-9-18(22)19(23)15-17/h8-9,15-16,20,24H,4-7,10-14H2,1-3H3/t20-/m1/s1
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 1.16n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202584
PNG
(US10035761, Compound 8h | US9238625, 8h)
Show SMILES COCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H31Cl2NO/c1-15(2)13-19(23-11-4-5-12-24-3)20(9-6-10-20)16-7-8-17(21)18(22)14-16/h7-8,14-15,19,23H,4-6,9-13H2,1-3H3/t19-/m1/s1
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 1.19n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202584
PNG
(US10035761, Compound 8h | US9238625, 8h)
Show SMILES COCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H31Cl2NO/c1-15(2)13-19(23-11-4-5-12-24-3)20(9-6-10-20)16-7-8-17(21)18(22)14-16/h7-8,14-15,19,23H,4-6,9-13H2,1-3H3/t19-/m1/s1
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 1.19n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202582
PNG
(US10035761, Compound 8a | US9238625, 8a)
Show SMILES CCOCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H29Cl2NO/c1-4-23-11-10-22-18(12-14(2)3)19(8-5-9-19)15-6-7-16(20)17(21)13-15/h6-7,13-14,18,22H,4-5,8-12H2,1-3H3
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 1.40n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202582
PNG
(US10035761, Compound 8a | US9238625, 8a)
Show SMILES CCOCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H29Cl2NO/c1-4-23-11-10-22-18(12-14(2)3)19(8-5-9-19)15-6-7-16(20)17(21)13-15/h6-7,13-14,18,22H,4-5,8-12H2,1-3H3
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 1.40n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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US Patent
 1.5n/a 2.25n/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...

US Patent US9604944 (2017)


BindingDB Entry DOI: 10.7270/Q2ZW1NZ2
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM218678
PNG
(US9296681, 33a-Racemic)
Show SMILES CC(C)CC(NCCCC(N)=O)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-13(2)11-17(23-10-3-5-18(22)24)19(8-4-9-19)14-6-7-15(20)16(21)12-14/h6-7,12-13,17,23H,3-5,8-11H2,1-2H3,(H2,22,24)
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 1.5n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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US Patent
 1.5n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...

J Med Chem 52: 2226-32 (2009)


BindingDB Entry DOI: 10.7270/Q2QZ2D9J
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM172725
PNG
(US9096515, 33a -Racemic)
Show SMILES CC(CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)
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 1.5n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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US Patent
 1.5n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172722
PNG
(US9096515, 21b | US9296681, 21b)
Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1
Show InChI InChI=1S/C22H36N2O3/c1-5-26-19-10-8-18(9-11-19)22(12-7-13-22)20(16-17(3)4)23-14-15-24-21(25)27-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3,(H,24,25)
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 2n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM172722
PNG
(US9096515, 21b | US9296681, 21b)
Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1
Show InChI InChI=1S/C22H36N2O3/c1-5-26-19-10-8-18(9-11-19)22(12-7-13-22)20(16-17(3)4)23-14-15-24-21(25)27-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3,(H,24,25)
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 2n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM172726
PNG
(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1
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 2.30n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172726
PNG
(US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...)
Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1
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 2.30n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202582
PNG
(US10035761, Compound 8a | US9238625, 8a)
Show SMILES CCOCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H29Cl2NO/c1-4-23-11-10-22-18(12-14(2)3)19(8-5-9-19)15-6-7-16(20)17(21)13-15/h6-7,13-14,18,22H,4-5,8-12H2,1-3H3
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 2.38n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202582
PNG
(US10035761, Compound 8a | US9238625, 8a)
Show SMILES CCOCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H29Cl2NO/c1-4-23-11-10-22-18(12-14(2)3)19(8-5-9-19)15-6-7-16(20)17(21)13-15/h6-7,13-14,18,22H,4-5,8-12H2,1-3H3
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 2.38n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202584
PNG
(US10035761, Compound 8h | US9238625, 8h)
Show SMILES COCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H31Cl2NO/c1-15(2)13-19(23-11-4-5-12-24-3)20(9-6-10-20)16-7-8-17(21)18(22)14-16/h7-8,14-15,19,23H,4-6,9-13H2,1-3H3/t19-/m1/s1
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US Patent
 2.39n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202584
PNG
(US10035761, Compound 8h | US9238625, 8h)
Show SMILES COCCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H31Cl2NO/c1-15(2)13-19(23-11-4-5-12-24-3)20(9-6-10-20)16-7-8-17(21)18(22)14-16/h7-8,14-15,19,23H,4-6,9-13H2,1-3H3/t19-/m1/s1
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 2.39n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 2.5n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM312188
PNG
(6-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)...)
Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Show InChI InChI=1S/C22H25Cl2N3O3/c23-17-4-3-5-19(22(17)24)27-11-9-26(10-12-27)8-1-2-13-29-16-6-7-20-18(14-16)25-21(28)15-30-20/h3-7,14H,1-2,8-13,15H2,(H,25,28)
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 2.70n/an/an/an/an/an/an/an/a



Reviva Pharmaceuticals, Inc.

US Patent


Assay Description
Serotonin, 5HT1A: Materials and Methods:Receptor Source: Human recombinant 5-HT1A expressed mammalian cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)C...

US Patent US10441590 (2019)


BindingDB Entry DOI: 10.7270/Q2959KXP
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM172729
PNG
(US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...)
Show SMILES CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1
Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m0/s1
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 2.79n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172729
PNG
(US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...)
Show SMILES CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1
Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m0/s1
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 2.79n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202581
PNG
(US10035761, Compound 7g | US9238625, 7g)
Show SMILES CCOCCCCNC(CC(C)C)C1(CCC1)c1ccc(SC)cc1
Show InChI InChI=1S/C22H37NOS/c1-5-24-16-7-6-15-23-21(17-18(2)3)22(13-8-14-22)19-9-11-20(25-4)12-10-19/h9-12,18,21,23H,5-8,13-17H2,1-4H3
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 2.99n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202581
PNG
(US10035761, Compound 7g | US9238625, 7g)
Show SMILES CCOCCCCNC(CC(C)C)C1(CCC1)c1ccc(SC)cc1
Show InChI InChI=1S/C22H37NOS/c1-5-24-16-7-6-15-23-21(17-18(2)3)22(13-8-14-22)19-9-11-20(25-4)12-10-19/h9-12,18,21,23H,5-8,13-17H2,1-4H3
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 2.99n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202587
PNG
(US10035761, Compound 12c | US9238625, 12c)
Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCSCC
Show InChI InChI=1S/C21H35NOS/c1-5-23-19-10-8-18(9-11-19)21(12-7-13-21)20(16-17(3)4)22-14-15-24-6-2/h8-11,17,20,22H,5-7,12-16H2,1-4H3
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 3.31n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202587
PNG
(US10035761, Compound 12c | US9238625, 12c)
Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCSCC
Show InChI InChI=1S/C21H35NOS/c1-5-23-19-10-8-18(9-11-19)21(12-7-13-21)20(16-17(3)4)22-14-15-24-6-2/h8-11,17,20,22H,5-7,12-16H2,1-4H3
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 3.31n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202583
PNG
(US10035761, Compound 8d | US9238625, 8d)
Show SMILES CCCOCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-12-25-13-6-11-24-20(14-16(2)3)21(9-5-10-21)17-7-8-18(22)19(23)15-17/h7-8,15-16,20,24H,4-6,9-14H2,1-3H3/t20-/m1/s1
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 3.80n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM202583
PNG
(US10035761, Compound 8d | US9238625, 8d)
Show SMILES CCCOCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-12-25-13-6-11-24-20(14-16(2)3)21(9-5-10-21)17-7-8-18(22)19(23)15-17/h7-8,15-16,20,24H,4-6,9-14H2,1-3H3/t20-/m1/s1
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 3.80n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202583
PNG
(US10035761, Compound 8d | US9238625, 8d)
Show SMILES CCCOCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-12-25-13-6-11-24-20(14-16(2)3)21(9-5-10-21)17-7-8-18(22)19(23)15-17/h7-8,15-16,20,24H,4-6,9-14H2,1-3H3/t20-/m1/s1
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 5.45n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9238625 (2016)


BindingDB Entry DOI: 10.7270/Q2CV4GKK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))		BDBM202583
PNG
(US10035761, Compound 8d | US9238625, 8d)
Show SMILES CCCOCCCN[C@H](CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C21H33Cl2NO/c1-4-12-25-13-6-11-24-20(14-16(2)3)21(9-5-10-21)17-7-8-18(22)19(23)15-17/h7-8,15-16,20,24H,4-6,9-14H2,1-3H3/t20-/m1/s1
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 5.45n/an/an/an/an/an/an/an/a



Revivia Pharmaceuticals, Inc.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected cycloalkylmethylamines of Formula (I) are reported herein. The compounds were evaluated ...

US Patent US10035761 (2018)


BindingDB Entry DOI: 10.7270/Q2D220N9
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM172728
PNG
(US9096515, 33b -Racemic | US9296681, 33b-Racemic)
Show SMILES CCOc1ccc(cc1)C1(CC(C)CCNCCCC(N)=O)CCC1
Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)
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 5.49n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...

US Patent US9296681 (2016)


BindingDB Entry DOI: 10.7270/Q22B8WW4
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172728
PNG
(US9096515, 33b -Racemic | US9296681, 33b-Racemic)
Show SMILES CCOc1ccc(cc1)C1(CC(C)CCNCCCC(N)=O)CCC1
Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)
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 5.49n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))		BDBM172720
PNG
(US9096515, 12u | US9296681, 12u)
Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCOC(=O)CC
Show InChI InChI=1S/C22H35NO3/c1-5-21(24)26-15-14-23-20(16-17(3)4)22(12-7-13-22)18-8-10-19(11-9-18)25-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3
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 5.70n/an/an/an/an/an/an/an/a



REVIVA PHARMACEUTICALS, INC.

US Patent


Assay Description
The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...

US Patent US9096515 (2015)


BindingDB Entry DOI: 10.7270/Q2Z60MTK
More data for this
Ligand-Target Pair
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