Compile Data Set for Download or QSAR

Found 83 hits with Last Name = 'lucchi' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50366495 ((+)butaclamol | CHEMBL1255588) Show SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 |r| Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidol				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048867 (1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) Show SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)CCCc12 Show InChI InChI=1S/C25H34N2O/c1-28-25-14-6-12-23-22(10-5-13-24(23)25)11-7-15-26-16-18-27(19-17-26)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22H,5,7,10-11,13,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using [3H]DTG as radioligand				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048876 (CHEMBL52372 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCCc3ccccc3)CCCc12 Show InChI InChI=1S/C23H31NO/c1-25-23-16-6-14-21-20(12-5-15-22(21)23)13-8-18-24-17-7-11-19-9-3-2-4-10-19/h2-4,6,9-10,14,16,20,24H,5,7-8,11-13,15,17-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048866 (1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...) Show SMILES COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12 Show InChI InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048867 (1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) Show SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)CCCc12 Show InChI InChI=1S/C25H34N2O/c1-28-25-14-6-12-23-22(10-5-13-24(23)25)11-7-15-26-16-18-27(19-17-26)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22H,5,7,10-11,13,15-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Opioid receptor sigma 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048875 (CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...) Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12 Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048868 (CHEMBL52849 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCC3CCCc4ccccc34)CCCc12 Show InChI InChI=1S/C26H35NO/c1-28-26-16-6-14-24-21(11-5-15-25(24)26)12-7-18-27-19-17-22-10-4-9-20-8-2-3-13-23(20)22/h2-3,6,8,13-14,16,21-22,27H,4-5,7,9-12,15,17-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50048867 (1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) Show SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)CCCc12 Show InChI InChI=1S/C25H34N2O/c1-28-25-14-6-12-23-22(10-5-13-24(23)25)11-7-15-26-16-18-27(19-17-26)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22H,5,7,10-11,13,15-20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048866 (1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...) Show SMILES COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12 Show InChI InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048870 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCN(CC3)C3=NCCCC3)c2c1 |t:20| Show InChI InChI=1S/C23H35N3O/c1-27-21-11-10-20-7-4-6-19(22(20)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h10-11,18-19H,2-9,12-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048869 (CHEMBL51630 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCc3ccccc3)CCCc12 Show InChI InChI=1S/C22H29NO/c1-24-22-14-6-12-20-19(10-5-13-21(20)22)11-7-16-23-17-15-18-8-3-2-4-9-18/h2-4,6,8-9,12,14,19,23H,5,7,10-11,13,15-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using [3H]DTG as radioligand				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048878 (1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...) Show SMILES C(CC1CCCc2ccccc12)CN1CCN(CC1)C1=NCCCC1 |t:22| Show InChI InChI=1S/C22H33N3/c1-2-11-21-19(7-1)8-5-9-20(21)10-6-14-24-15-17-25(18-16-24)22-12-3-4-13-23-22/h1-2,7,11,20H,3-6,8-10,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048878 (1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...) Show SMILES C(CC1CCCc2ccccc12)CN1CCN(CC1)C1=NCCCC1 |t:22| Show InChI InChI=1S/C22H33N3/c1-2-11-21-19(7-1)8-5-9-20(21)10-6-14-24-15-17-25(18-16-24)22-12-3-4-13-23-22/h1-2,7,11,20H,3-6,8-10,12-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048873 (1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...) Show SMILES C(CN1CCN(Cc2ccccc2)CC1)CC1=CCCc2ccccc12 |t:18| Show InChI InChI=1S/C24H30N2/c1-2-8-21(9-3-1)20-26-18-16-25(17-19-26)15-7-13-23-12-6-11-22-10-4-5-14-24(22)23/h1-5,8-10,12,14H,6-7,11,13,15-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054122 (2-[4-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-butyl]-1...) Show SMILES C(CCN1CCc2ccccc2C1)CC1CCCc2ccccc12 Show InChI InChI=1S/C23H29N/c1-2-11-22-18-24(17-15-19(22)8-1)16-6-5-10-21-13-7-12-20-9-3-4-14-23(20)21/h1-4,8-9,11,14,21H,5-7,10,12-13,15-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50048866 (1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...) Show SMILES COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12 Show InChI InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50048878 (1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...) Show SMILES C(CC1CCCc2ccccc12)CN1CCN(CC1)C1=NCCCC1 |t:22| Show InChI InChI=1S/C22H33N3/c1-2-11-21-19(7-1)8-5-9-20(21)10-6-14-24-15-17-25(18-16-24)22-12-3-4-13-23-22/h1-2,7,11,20H,3-6,8-10,12-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048877 (1-Benzyl-4-[3-(5-methoxy-3,4-dihydro-naphthalen-1-...) Show SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)=CCCc12 |c:25| Show InChI InChI=1S/C25H32N2O/c1-28-25-14-6-12-23-22(10-5-13-24(23)25)11-7-15-26-16-18-27(19-17-26)20-21-8-3-2-4-9-21/h2-4,6,8-10,12,14H,5,7,11,13,15-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using [3H]DTG as radioligand				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048876 (CHEMBL52372 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCCc3ccccc3)CCCc12 Show InChI InChI=1S/C23H31NO/c1-25-23-16-6-14-21-20(12-5-15-22(21)23)13-8-18-24-17-7-11-19-9-3-2-4-10-19/h2-4,6,9-10,14,16,20,24H,5,7-8,11-13,15,17-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048869 (CHEMBL51630 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCc3ccccc3)CCCc12 Show InChI InChI=1S/C22H29NO/c1-24-22-14-6-12-20-19(10-5-13-21(20)22)11-7-16-23-17-15-18-8-3-2-4-9-18/h2-4,6,8-9,12,14,19,23H,5,7,10-11,13,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054118 (CHEMBL135528 | Dipropyl-[4-(1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)CCCCC1CCCc2ccccc12 Show InChI InChI=1S/C20H33N/c1-3-15-21(16-4-2)17-8-7-11-19-13-9-12-18-10-5-6-14-20(18)19/h5-6,10,14,19H,3-4,7-9,11-13,15-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048873 (1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...) Show SMILES C(CN1CCN(Cc2ccccc2)CC1)CC1=CCCc2ccccc12 |t:18| Show InChI InChI=1S/C24H30N2/c1-2-8-21(9-3-1)20-26-18-16-25(17-19-26)15-7-13-23-12-6-11-22-10-4-5-14-24(22)23/h1-5,8-10,12,14H,6-7,11,13,15-20H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048875 (CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...) Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12 Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048872 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCNCC3)c2c1 Show InChI InChI=1S/C18H28N2O/c1-21-17-8-7-16-5-2-4-15(18(16)14-17)6-3-11-20-12-9-19-10-13-20/h7-8,14-15,19H,2-6,9-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054113 (4-Benzyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)...) Show SMILES C(CCN1CCC(Cc2ccccc2)CC1)CC1CCCc2ccccc12 Show InChI InChI=1S/C26H35N/c1-2-9-22(10-3-1)21-23-16-19-27(20-17-23)18-7-6-12-25-14-8-13-24-11-4-5-15-26(24)25/h1-5,9-11,15,23,25H,6-8,12-14,16-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054112 (CHEMBL135530 | [4-(3,4-Dihydro-naphthalen-1-yl)-bu...) Show SMILES CCCN(CCC)CCCCC1=CCCc2ccccc12 |t:11| Show InChI InChI=1S/C20H31N/c1-3-15-21(16-4-2)17-8-7-11-19-13-9-12-18-10-5-6-14-20(18)19/h5-6,10,13-14H,3-4,7-9,11-12,15-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50368882 (CHEMBL147585 | SK&F-10047 | SK-10047) Show SMILES CC1C2Cc3ccc(O)cc3C1CCN2CC=C |TLB:0:1:10.4.3:14.12.13,15:14:1:10.4.3,THB:9:10:1:14.12.13| Show InChI InChI=1S/C16H21NO/c1-3-7-17-8-6-14-11(2)16(17)9-12-4-5-13(18)10-15(12)14/h3-5,10-11,14,16,18H,1,6-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested on Phencyclidine binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50368882 (CHEMBL147585 | SK&F-10047 | SK-10047) Show SMILES CC1C2Cc3ccc(O)cc3C1CCN2CC=C |TLB:0:1:10.4.3:14.12.13,15:14:1:10.4.3,THB:9:10:1:14.12.13| Show InChI InChI=1S/C16H21NO/c1-3-7-17-8-6-14-11(2)16(17)9-12-4-5-13(18)10-15(12)14/h3-5,10-11,14,16,18H,1,6-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	396	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054115 (CHEMBL135930 | Dipropyl-[3-(1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)CCCC1CCCc2ccccc12 Show InChI InChI=1S/C19H31N/c1-3-14-20(15-4-2)16-8-12-18-11-7-10-17-9-5-6-13-19(17)18/h5-6,9,13,18H,3-4,7-8,10-12,14-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048870 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCN(CC3)C3=NCCCC3)c2c1 |t:20| Show InChI InChI=1S/C23H35N3O/c1-27-21-11-10-20-7-4-6-19(22(20)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h10-11,18-19H,2-9,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	414	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048868 (CHEMBL52849 | [3-(5-Methoxy-1,2,3,4-tetrahydro-nap...) Show SMILES COc1cccc2C(CCCNCCC3CCCc4ccccc34)CCCc12 Show InChI InChI=1S/C26H35NO/c1-28-26-16-6-14-24-21(11-5-15-25(24)26)12-7-18-27-19-17-22-10-4-9-20-8-2-3-13-23(20)22/h2-3,6,8,13-14,16,21-22,27H,4-5,7,9-12,15,17-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	469	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50048874 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCNCC3)CCCc12 Show InChI InChI=1S/C18H28N2O/c1-21-18-9-3-7-16-15(5-2-8-17(16)18)6-4-12-20-13-10-19-11-14-20/h3,7,9,15,19H,2,4-6,8,10-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>877	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membrane				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054124 (1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCN3CCCC(C)(C)C3)CCCc12 Show InChI InChI=1S/C21H33NO/c1-21(2)13-7-15-22(16-21)14-6-9-17-8-4-11-19-18(17)10-5-12-20(19)23-3/h5,10,12,17H,4,6-9,11,13-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	898	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50054116 (4-Benzyl-1-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) Show SMILES COc1cccc2C(CCCN3CCC(Cc4ccccc4)CC3)CCCc12 Show InChI InChI=1S/C26H35NO/c1-28-26-14-6-12-24-23(10-5-13-25(24)26)11-7-17-27-18-15-22(16-19-27)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22-23H,5,7,10-11,13,15-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity of compound towards Dopamine receptor D2 was determined in rat striatal homogenate using [3H]- spiperone as radioligand				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054121 (3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES CC1(C)CCCN(CCCCC2CCCc3ccccc23)C1 Show InChI InChI=1S/C21H33N/c1-21(2)14-8-16-22(17-21)15-6-5-10-19-12-7-11-18-9-3-4-13-20(18)19/h3-4,9,13,19H,5-8,10-12,14-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054110 (1-[4-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-butyl]-p...) Show SMILES C(CCN1CCCCC1)CC1CCCc2ccccc12 Show InChI InChI=1S/C19H29N/c1-5-14-20(15-6-1)16-7-4-10-18-12-8-11-17-9-2-3-13-19(17)18/h2-3,9,13,18H,1,4-8,10-12,14-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054120 (1-[3-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-propyl]-...) Show SMILES C(CC1CCCc2ccccc12)CN1CCCCC1 Show InChI InChI=1S/C18H27N/c1-4-13-19(14-5-1)15-7-11-17-10-6-9-16-8-2-3-12-18(16)17/h2-3,8,12,17H,1,4-7,9-11,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048872 (1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1ccc2CCCC(CCCN3CCNCC3)c2c1 Show InChI InChI=1S/C18H28N2O/c1-21-17-8-7-16-5-2-4-15(18(16)14-17)6-3-11-20-12-9-19-10-13-20/h7-8,14-15,19H,2-6,9-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50048874 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCNCC3)CCCc12 Show InChI InChI=1S/C18H28N2O/c1-21-18-9-3-7-16-15(5-2-8-17(16)18)6-4-12-20-13-10-19-11-14-20/h3,7,9,15,19H,2,4-6,8,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserin				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054111 (3,3-Dimethyl-1-[3-(4,5,6,7-tetrahydro-benzo[c]thio...) Show SMILES CC1(C)CCCN(CCCC2CCCc3cscc23)C1 Show InChI InChI=1S/C18H29NS/c1-18(2)9-5-11-19(14-18)10-4-8-15-6-3-7-16-12-20-13-17(15)16/h12-13,15H,3-11,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054119 (1-[3-(4,5,6,7-Tetrahydro-benzo[c]thiophen-4-yl)-pr...) Show SMILES C(CC1CCCc2cscc12)CN1CCCCC1 Show InChI InChI=1S/C16H25NS/c1-2-9-17(10-3-1)11-5-8-14-6-4-7-15-12-18-13-16(14)15/h12-14H,1-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair

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