Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521182![]() (CHEMBL4456312 | US11260049, Ex. 123) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521192![]() (CHEMBL4547537 | US11260049, Ex. 121) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521183![]() (CHEMBL4461475 | US11260049, Ex. 125) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50521183![]() (CHEMBL4461475 | US11260049, Ex. 125) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 m... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50554960![]() (CHEMBL4749555) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human TRPV4 expressed in BHK or HEK MSR2 cells assessed as inhibition of TRPV4 agonist GSK634775 (EC80)-induced response incub... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01303 BindingDB Entry DOI: 10.7270/Q2XW4PFK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50502640![]() (CHEMBL4470585) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 | J Med Chem 62: 9270-9280 (2019) Article DOI: 10.1021/acs.jmedchem.9b01247 BindingDB Entry DOI: 10.7270/Q2N30173 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521185![]() (CHEMBL4439448 | US11260049, Ex. 83) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521195![]() (CHEMBL4586959 | US11260049, Ex. 84) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505550![]() (CHEMBL4439190 | US11260049, Ex. 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521186![]() (CHEMBL4547101 | US11260049, Ex. 45) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505550![]() (CHEMBL4439190 | US11260049, Ex. 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at human TRPV4 | J Med Chem 62: 9270-9280 (2019) Article DOI: 10.1021/acs.jmedchem.9b01247 BindingDB Entry DOI: 10.7270/Q2N30173 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505551![]() (CHEMBL4517101) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at BacMam virus expressing human TRPV4 transduced in BHK/AC9 or HEK MSR2 cells assessed as inhibition of GSK634775-induced Ca2+ f... | J Med Chem 62: 9270-9280 (2019) Article DOI: 10.1021/acs.jmedchem.9b01247 BindingDB Entry DOI: 10.7270/Q2N30173 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505543![]() (CHEMBL4454801) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Antagonist activity at BacMam virus expressing human TRPV4 transduced in BHK/AC9 or HEK MSR2 cells assessed as inhibition of GSK634775-induced Ca2+ f... | J Med Chem 62: 9270-9280 (2019) Article DOI: 10.1021/acs.jmedchem.9b01247 BindingDB Entry DOI: 10.7270/Q2N30173 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50505550![]() (CHEMBL4439190 | US11260049, Ex. 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 m... | J Med Chem 61: 11209-11220 (2018) Article DOI: 10.1021/acs.jmedchem.8b01344 BindingDB Entry DOI: 10.7270/Q2KW5KD5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Short transient receptor potential channel 6 (Homo sapiens (Human)) | BDBM50439218![]() (CHEMBL2418809) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay | Bioorg Med Chem Lett 23: 4979-84 (2013) Article DOI: 10.1016/j.bmcl.2013.06.047 BindingDB Entry DOI: 10.7270/Q2319X9H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539936![]() (4-(((3R,4S)-4-((4-bromophenyl)sulfonyl)-3-hydroxy-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539981![]() (3-chloro-4-(((3R,4S)-4-((5-chloropyridin-2-yl)sulf...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539910![]() (4-(((3R,4S)-4- ((4-chloro- phenyl)sulfonyl)- 3-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521180![]() (CHEMBL4437115 | US11260049, Ex. 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505550![]() (CHEMBL4439190 | US11260049, Ex. 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539865![]() (4-(((3S,4S)-1- ((2-chloro-4- cyanophenyl)sulfonyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539874![]() (4-(((3S,4R)-1- ((2-chloro-4- fluorophenyl)sulfonyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539875![]() (4-(((3S,4R)-1- ((2-chloro-4- methylphenyl)sulfonyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539876![]() (2-chloro-4-(difluoro- methyl)benzene-1- sulfonyl c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539872![]() (4-(((3S,4R)-1- ((2-chloro-4- cyanophenyl)sulfonyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539878![]() (4-chloro-2- methoxybenzene- 1-sulfonyl chloride | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539879![]() (5-chloro-2- (((3R,4S)-4-((4- chlorophenyl)sulfonyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539916![]() (3-chloro-4- (((3R,4S)-3- hydroxy-3- (hydroxymethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539917![]() (3- (difluoromethyl)- 4-(((3R,4S)-3- hydroxy-3- (hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539921![]() (4-(((3S,4R)-1- ((2-bromo-4- chlorophenyl)sulfonyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539969![]() (3-chloro-4- (((3R,4S)-4-((4- chloro-3- fluoropheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521192![]() (CHEMBL4547537 | US11260049, Ex. 121) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521182![]() (CHEMBL4456312 | US11260049, Ex. 123) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521183![]() (CHEMBL4461475 | US11260049, Ex. 125) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539932![]() (4-(((3S,4R)-1- ((4-cyano-2-methyl- phenyl)sulfonyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539937![]() (4-(((3S,4S)-1- ((2,4- dichlorophenyl) sulfonyl)-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50505546![]() (CHEMBL4533534 | US11260049, Ex. 82) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521195![]() (CHEMBL4586959 | US11260049, Ex. 84) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539949![]() (4-(((3S,4R)-1- ((2,4- dichlorophenyl) sulfonyl)-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539881![]() (4-(((3R,4S)-4- ((4-chloro- phenyl)sulfonyl)- 3-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539887![]() (4-(((3S,4R)-1- ((4-chloro-2- (trifluoromethyl) phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539891![]() (4-(((3S,4R)-1- ((4-fluoro-2- (trifluoromethyl) phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539892![]() (4-(((3S,4R)-1- ((4-bromo-2- (trifluoromethyl) phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539896![]() (4-(((3S,4R)-1- ((4-bromo-2- chlorophenyl)sulfonyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539897![]() (4-(((3R,4S)-4- ((4-chloro- phenyl)sulfonyl)- 3-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539900![]() (3-bromo-4- (((3R,4S)-4-((4- chlorophenyl)sulfonyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM50521186![]() (CHEMBL4547101 | US11260049, Ex. 45) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539975![]() (4-(((3R,4S)-4-((5- bromopyridin-2- yl)sulfonyl)-3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539979![]() (2-(((3R,4S)-4-((4- chlorophenyl) sulfonyl)-3- hydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human)) | BDBM539982![]() (3-chloro-4-(((3R,4S)-4-((5-chloropyridin-2-yl)sulf...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2B85C9Z | |||||||||||
More data for this Ligand-Target Pair |
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