Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JARID1C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50130725 (3-(3-Chloro-4-hydroxy-phenylamino)-4-(2-nitro-phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM50396018 (CHEMBL1230640) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM50396018 (CHEMBL1230640) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JARID1C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50396018 (CHEMBL1230640) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50396018 (CHEMBL1230640) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495469 (CHEMBL3108953) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50495471 (CHEMBL3108959) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in Pichia pastoris using kynuramine as substrate after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495473 (CHEMBL3108955) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495471 (CHEMBL3108959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495470 (CHEMBL3108954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50240772 ((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50535403 (CHEMBL4590543) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino... | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50240772 ((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in Pichia pastoris using benzylamine as substrate after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495473 (CHEMBL3108955) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50535402 (CHEMBL4449010) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495471 (CHEMBL3108959) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM50495468 (CHEMBL3108958) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495470 (CHEMBL3108954) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50535402 (CHEMBL4449010) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant his tagged HDAC6 expressed in baculovirus infected Sf6 insect cells using batcp as substrate incubated for 1 hr by fl... | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50495470 (CHEMBL3108954) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50535401 (CHEMBL4443876) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino... | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50535400 (CHEMBL4575045) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50495469 (CHEMBL3108953) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50240772 ((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in Pichia pastoris using kynuramine as substrate after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50535400 (CHEMBL4575045) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus infected Sf6 insect cells using tertbutyloxycarbonyl (Boc)-(Ac)-Lys-7-amino... | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50495473 (CHEMBL3108955) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4E (Homo sapiens (Human)) | BDBM50495469 (CHEMBL3108953) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50495470 (CHEMBL3108954) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Egl nine homolog 1 (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of PHD2 (unknown origin) by mass spectrometry | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5C (Homo sapiens (Human)) | BDBM50495471 (CHEMBL3108959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JARID1C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50495472 (CHEMBL3108952) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in Pichia pastoris using kynuramine as substrate after 5 mins | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM50495473 (CHEMBL3108955) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM50495470 (CHEMBL3108954) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50535403 (CHEMBL4590543) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Alma Mater Studiorum-University of Bologna Curated by ChEMBL | Assay Description Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assay | ACS Med Chem Lett 10: 469-474 (2019) Article DOI: 10.1021/acsmedchemlett.8b00507 BindingDB Entry DOI: 10.7270/Q2HD805P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM26119 (2-[4-(methoxycarbonyl)pyridin-2-yl]pyridine-4-carb...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Rome Curated by ChEMBL | Assay Description Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method | J Med Chem 57: 42-55 (2014) Article DOI: 10.1021/jm4012802 BindingDB Entry DOI: 10.7270/Q2028VHD | |||||||||||
More data for this Ligand-Target Pair |
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