Compile Data Set for Download or QSAR

Found 133 hits with Last Name = 'gazdik' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50528308 (CHEMBL4460082) Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H18F3N3O5S/c1-34(32,33)28-16-8-6-14(7-9-16)21(29)26-20(22(30)27-31)13-4-2-12(3-5-13)15-10-17(23)19(25)18(24)11-15/h2-11,20,28,31H,1H3,(H,26,29)(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528311 (CHEMBL4448936) Show SMILES NS(=O)(=O)Nc1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H17F3N4O5S/c22-16-9-14(10-17(23)18(16)24)11-1-3-12(4-2-11)19(21(30)27-31)26-20(29)13-5-7-15(8-6-13)28-34(25,32)33/h1-10,19,28,31H,(H,26,29)(H,27,30)(H2,25,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528345 (CHEMBL4445188) Show SMILES ONC(=O)C(NC(=O)c1ccc2[nH]ncc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H15F3N4O3/c23-16-8-14(9-17(24)19(16)25)11-1-3-12(4-2-11)20(22(31)29-32)27-21(30)13-5-6-18-15(7-13)10-26-28-18/h1-10,20,32H,(H,26,28)(H,27,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528319 (CHEMBL4566015) Show SMILES ONC(=O)C(NC(=O)c1ccc2[nH]nnc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F3N5O3/c22-14-7-13(8-15(23)18(14)24)10-1-3-11(4-2-10)19(21(31)28-32)25-20(30)12-5-6-16-17(9-12)27-29-26-16/h1-9,19,32H,(H,25,30)(H,28,31)(H,26,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528321 (CHEMBL4522953) Show SMILES ONC(=O)C(NC(=O)c1ccc(O)c(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F4N2O4/c22-14-7-12(5-6-17(14)28)20(29)26-19(21(30)27-31)11-3-1-10(2-4-11)13-8-15(23)18(25)16(24)9-13/h1-9,19,28,31H,(H,26,29)(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528338 (CHEMBL4590563) Show SMILES N\C(=N/O)c1cccc(c1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N4O4/c23-16-9-15(10-17(24)18(16)25)11-4-6-12(7-5-11)19(22(31)29-33)27-21(30)14-3-1-2-13(8-14)20(26)28-32/h1-10,19,32-33H,(H2,26,28)(H,27,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528320 (CHEMBL4578880) Show SMILES ONC(=O)C(NC(=O)c1ccc(F)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F4N2O4/c22-14-6-5-12(9-17(14)28)20(29)26-19(21(30)27-31)11-3-1-10(2-4-11)13-7-15(23)18(25)16(24)8-13/h1-9,19,28,31H,(H,26,29)(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528313 (CHEMBL4544937) Show SMILES ONC(=O)C(NC(=O)Cc1ccc(O)c(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F4N2O4/c23-15-7-11(1-6-18(15)29)8-19(30)27-21(22(31)28-32)13-4-2-12(3-5-13)14-9-16(24)20(26)17(25)10-14/h1-7,9-10,21,29,32H,8H2,(H,27,30)(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528328 (CHEMBL4589359) Show SMILES N\C(=N/O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N4O4/c23-16-9-15(10-17(24)18(16)25)11-1-3-12(4-2-11)19(22(31)29-33)27-21(30)14-7-5-13(6-8-14)20(26)28-32/h1-10,19,32-33H,(H2,26,28)(H,27,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528310 (CHEMBL4455419) Show SMILES NC(=O)c1cccc(c1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F3N3O4/c23-16-9-15(10-17(24)18(16)25)11-4-6-12(7-5-11)19(22(31)28-32)27-21(30)14-3-1-2-13(8-14)20(26)29/h1-10,19,32H,(H2,26,29)(H,27,30)(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528327 (CHEMBL4586845) Show SMILES NC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F3N3O4/c23-16-9-15(10-17(24)18(16)25)11-1-3-12(4-2-11)19(22(31)28-32)27-21(30)14-7-5-13(6-8-14)20(26)29/h1-10,19,32H,(H2,26,29)(H,27,30)(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528349 (CHEMBL4441367) Show SMILES ONC(=O)C(NC(=O)c1ccc(O)cc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H15F3N2O4/c22-16-9-14(10-17(23)18(16)24)11-1-3-12(4-2-11)19(21(29)26-30)25-20(28)13-5-7-15(27)8-6-13/h1-10,19,27,30H,(H,25,28)(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528337 (CHEMBL4446709) Show SMILES ONC(=O)C(NC(=O)c1ccc2[nH]ccc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C23H16F3N3O3/c24-17-10-16(11-18(25)20(17)26)12-1-3-13(4-2-12)21(23(31)29-32)28-22(30)15-5-6-19-14(9-15)7-8-27-19/h1-11,21,27,32H,(H,28,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528335 (CHEMBL3765455) Show SMILES CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C19H19F3N2O3/c1-19(2,3)18(26)23-16(17(25)24-27)11-6-4-10(5-7-11)12-8-13(20)15(22)14(21)9-12/h4-9,16,27H,1-3H3,(H,23,26)(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528314 (CHEMBL4572202) Show SMILES COc1ccc(CC(=O)NC(C(=O)NO)c2ccc(cc2)-c2cc(F)c(F)c(F)c2)cc1OC Show InChI InChI=1S/C24H21F3N2O5/c1-33-19-8-3-13(9-20(19)34-2)10-21(30)28-23(24(31)29-32)15-6-4-14(5-7-15)16-11-17(25)22(27)18(26)12-16/h3-9,11-12,23,32H,10H2,1-2H3,(H,28,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528342 (CHEMBL4435512) Show SMILES Nc1cccc(c1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H16F3N3O3/c22-16-9-14(10-17(23)18(16)24)11-4-6-12(7-5-11)19(21(29)27-30)26-20(28)13-2-1-3-15(25)8-13/h1-10,19,30H,25H2,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528343 (CHEMBL4554326) Show SMILES ONC(=O)C(NC(=O)Cc1ccc(O)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N2O5/c23-15-9-14(10-16(24)20(15)25)12-2-4-13(5-3-12)21(22(31)27-32)26-19(30)8-11-1-6-17(28)18(29)7-11/h1-7,9-10,21,28-29,32H,8H2,(H,26,30)(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528309 (CHEMBL4588933) Show SMILES ONC(=O)C(NC(=O)Cc1ccc(F)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F4N2O4/c23-15-6-1-11(7-18(15)29)8-19(30)27-21(22(31)28-32)13-4-2-12(3-5-13)14-9-16(24)20(26)17(25)10-14/h1-7,9-10,21,29,32H,8H2,(H,27,30)(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528307 (CHEMBL4593147) Show SMILES ONC(=O)C(NC(=O)c1ccc2NC(=O)Cc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C23H16F3N3O4/c24-16-8-14(9-17(25)20(16)26)11-1-3-12(4-2-11)21(23(32)29-33)28-22(31)13-5-6-18-15(7-13)10-19(30)27-18/h1-9,21,33H,10H2,(H,27,30)(H,28,31)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528344 (CHEMBL4537181) Show SMILES ONC(=O)C(NC(=O)Cc1ccc(F)cc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F4N2O3/c23-16-7-1-12(2-8-16)9-19(29)27-21(22(30)28-31)14-5-3-13(4-6-14)15-10-17(24)20(26)18(25)11-15/h1-8,10-11,21,31H,9H2,(H,27,29)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528347 (CHEMBL4462042) Show SMILES OCCNC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C24H20F3N3O5/c25-18-11-17(12-19(26)20(18)27)13-1-3-14(4-2-13)21(24(34)30-35)29-23(33)16-7-5-15(6-8-16)22(32)28-9-10-31/h1-8,11-12,21,31,35H,9-10H2,(H,28,32)(H,29,33)(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528318 (CHEMBL4564549) Show SMILES ONC(=O)C(NC(=O)c1ccc2[nH]cnc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H15F3N4O3/c23-15-7-14(8-16(24)19(15)25)11-1-3-12(4-2-11)20(22(31)29-32)28-21(30)13-5-6-17-18(9-13)27-10-26-17/h1-10,20,32H,(H,26,27)(H,28,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528339 (CHEMBL4459712) Show SMILES ONC(=O)C(NC(=O)CCC(O)=O)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C18H15F3N2O5/c19-12-7-11(8-13(20)16(12)21)9-1-3-10(4-2-9)17(18(27)23-28)22-14(24)5-6-15(25)26/h1-4,7-8,17,28H,5-6H2,(H,22,24)(H,23,27)(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528322 (CHEMBL4579696) Show SMILES COc1ccc(cc1OC)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C23H19F3N2O5/c1-32-18-8-7-14(11-19(18)33-2)22(29)27-21(23(30)28-31)13-5-3-12(4-6-13)15-9-16(24)20(26)17(25)10-15/h3-11,21,31H,1-2H3,(H,27,29)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528348 (CHEMBL4566082) Show SMILES CN(C)C(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C24H20F3N3O4/c1-30(2)24(33)16-9-7-15(8-10-16)22(31)28-21(23(32)29-34)14-5-3-13(4-6-14)17-11-18(25)20(27)19(26)12-17/h3-12,21,34H,1-2H3,(H,28,31)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528326 (CHEMBL4462406) Show SMILES CNC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C23H18F3N3O4/c1-27-21(30)14-6-8-15(9-7-14)22(31)28-20(23(32)29-33)13-4-2-12(3-5-13)16-10-17(24)19(26)18(25)11-16/h2-11,20,33H,1H3,(H,27,30)(H,28,31)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528351 (CHEMBL4475350) Show SMILES ONC(=O)C(NC(=O)CC(O)=O)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C17H13F3N2O5/c18-11-5-10(6-12(19)15(11)20)8-1-3-9(4-2-8)16(17(26)22-27)21-13(23)7-14(24)25/h1-6,16,27H,7H2,(H,21,23)(H,22,26)(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528323 (CHEMBL4439556) Show SMILES Nc1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H16F3N3O3/c22-16-9-14(10-17(23)18(16)24)11-1-3-12(4-2-11)19(21(29)27-30)26-20(28)13-5-7-15(25)8-6-13/h1-10,19,30H,25H2,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528316 (CHEMBL4468609) Show SMILES ONC(=O)C(NC(=O)Cc1ccc(O)cc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N2O4/c23-17-10-15(11-18(24)20(17)25)13-3-5-14(6-4-13)21(22(30)27-31)26-19(29)9-12-1-7-16(28)8-2-12/h1-8,10-11,21,28,31H,9H2,(H,26,29)(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528352 (CHEMBL4535765) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H16F3N3O5S/c22-16-9-14(10-17(23)18(16)24)11-1-3-12(4-2-11)19(21(29)27-30)26-20(28)13-5-7-15(8-6-13)33(25,31)32/h1-10,19,30H,(H,26,28)(H,27,29)(H2,25,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528325 (CHEMBL4440454) Show SMILES CCNC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C24H20F3N3O4/c1-2-28-22(31)15-7-9-16(10-8-15)23(32)29-21(24(33)30-34)14-5-3-13(4-6-14)17-11-18(25)20(27)19(26)12-17/h3-12,21,34H,2H2,1H3,(H,28,31)(H,29,32)(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528333 (CHEMBL4460369) Show SMILES ONC(=O)CC(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C17H14F3N3O5/c18-11-5-10(6-12(19)15(11)20)8-1-3-9(4-2-8)16(17(26)23-28)21-13(24)7-14(25)22-27/h1-6,16,27-28H,7H2,(H,21,24)(H,22,25)(H,23,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	348	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528329 (CHEMBL4562848) Show SMILES ONC(=O)C(NC(=O)c1cccc(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H15F3N2O4/c22-16-9-14(10-17(23)18(16)24)11-4-6-12(7-5-11)19(21(29)26-30)25-20(28)13-2-1-3-15(27)8-13/h1-10,19,27,30H,(H,25,28)(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	366	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528346 (CHEMBL4442426) Show SMILES ONC(=O)C(NC(=O)c1ccc(O)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H15F3N2O5/c22-14-7-13(8-15(23)18(14)24)10-1-3-11(4-2-10)19(21(30)26-31)25-20(29)12-5-6-16(27)17(28)9-12/h1-9,19,27-28,31H,(H,25,29)(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528341 (CHEMBL4440320) Show SMILES ONC(=O)C(NC(=O)Cc1cccc(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H16F4N2O3/c23-16-3-1-2-12(8-16)9-19(29)27-21(22(30)28-31)14-6-4-13(5-7-14)15-10-17(24)20(26)18(25)11-15/h1-8,10-11,21,31H,9H2,(H,27,29)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	442	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528340 (CHEMBL4531395) Show SMILES COc1cccc(c1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N2O4/c1-31-16-4-2-3-14(9-16)21(28)26-20(22(29)27-30)13-7-5-12(6-8-13)15-10-17(23)19(25)18(24)11-15/h2-11,20,30H,1H3,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	462	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528306 (CHEMBL4458367) Show SMILES NC(=O)CCC(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C18H16F3N3O4/c19-12-7-11(8-13(20)16(12)21)9-1-3-10(4-2-9)17(18(27)24-28)23-15(26)6-5-14(22)25/h1-4,7-8,17,28H,5-6H2,(H2,22,25)(H,23,26)(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	497	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528332 (CHEMBL4540925) Show SMILES ONC(=O)C(NC(=O)c1ccccc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H15F3N2O3/c22-16-10-15(11-17(23)18(16)24)12-6-8-13(9-7-12)19(21(28)26-29)25-20(27)14-4-2-1-3-5-14/h1-11,19,29H,(H,25,27)(H,26,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	522	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528334 (CHEMBL4467963) Show SMILES CC(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C16H13F3N2O3/c1-8(22)20-15(16(23)21-24)10-4-2-9(3-5-10)11-6-12(17)14(19)13(18)7-11/h2-7,15,24H,1H3,(H,20,22)(H,21,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528315 (CHEMBL4439575) Show SMILES NC(=O)c1ccc(CC(=O)NC(C(=O)NO)c2ccc(cc2)-c2cc(F)c(F)c(F)c2)cc1 Show InChI InChI=1S/C23H18F3N3O4/c24-17-10-16(11-18(25)20(17)26)13-5-7-14(8-6-13)21(23(32)29-33)28-19(30)9-12-1-3-15(4-2-12)22(27)31/h1-8,10-11,21,33H,9H2,(H2,27,31)(H,28,30)(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	604	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528324 (CHEMBL4586126) Show SMILES CC(C)NC(=O)c1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C25H22F3N3O4/c1-13(2)29-23(32)16-7-9-17(10-8-16)24(33)30-22(25(34)31-35)15-5-3-14(4-6-15)18-11-19(26)21(28)20(27)12-18/h3-13,22,35H,1-2H3,(H,29,32)(H,30,33)(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528331 (CHEMBL4445018) Show SMILES ONC(=O)C(NC(=O)c1ccc(F)cc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F4N2O3/c22-15-7-5-13(6-8-15)20(28)26-19(21(29)27-30)12-3-1-11(2-4-12)14-9-16(23)18(25)17(24)10-14/h1-10,19,30H,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	704	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528330 (CHEMBL4454625) Show SMILES COc1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N2O4/c1-31-16-8-6-14(7-9-16)21(28)26-20(22(29)27-30)13-4-2-12(3-5-13)15-10-17(23)19(25)18(24)11-15/h2-11,20,30H,1H3,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	745	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528350 (CHEMBL4571223) Show SMILES ONC(=O)C(NC(=O)c1cccc(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F4N2O3/c22-15-3-1-2-13(8-15)20(28)26-19(21(29)27-30)12-6-4-11(5-7-12)14-9-16(23)18(25)17(24)10-14/h1-10,19,30H,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	919	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528336 (CHEMBL4446876) Show SMILES COc1ccc(CC(=O)NC(C(=O)NO)c2ccc(cc2)-c2cc(F)c(F)c(F)c2)cc1 Show InChI InChI=1S/C23H19F3N2O4/c1-32-17-8-2-13(3-9-17)10-20(29)27-22(23(30)28-31)15-6-4-14(5-7-15)16-11-18(24)21(26)19(25)12-16/h2-9,11-12,22,31H,10H2,1H3,(H,27,29)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	978	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50277143 (CHR 2797 | CHR-2797 | Tosedostat) Show SMILES CC(C)C[C@H]([C@H](O)C(=O)NO)C(=O)N[C@H](C(=O)OC1CCCC1)c1ccccc1 |r| Show InChI InChI=1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17+,18+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aminopeptidase N (Homo sapiens (Human))	BDBM50528317 (CHEMBL4564908) Show SMILES ONC(=O)C(NC(=O)Cc1ccccc1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C22H17F3N2O3/c23-17-11-16(12-18(24)20(17)25)14-6-8-15(9-7-14)21(22(29)27-30)26-19(28)10-13-4-2-1-3-5-13/h1-9,11-12,21,30H,10H2,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50528312 (CHEMBL4439004) Show SMILES Cl.ONC(=O)C(NCc1ccc(F)c(O)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H16F4N2O3.ClH/c22-15-6-1-11(7-18(15)28)10-26-20(21(29)27-30)13-4-2-12(3-5-13)14-8-16(23)19(25)17(24)9-14;/h1-9,20,26,28,30H,10H2,(H,27,29);1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |r| Show InChI InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of MMP2 (unknown origin) using QF-24 as substrate preincubated for 1 hr followed by substrate addition and measured at 1 min interval for ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757 BindingDB Entry DOI: 10.7270/Q2KK9G8J
					More data for this Ligand-Target Pair

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