BindingDB PrimarySearch

Found 23 hits with Last Name = 'shaquiquzzaman' and Initial = 'm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50305146 (4-amino-5-(2,6-difluorobenzoyl)-2-(4-phenoxyphenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50510873 (CHEMBL4436337) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of EGFR T790M mutant (unknown origin) incubated for 60 mins by ADP-Glo kinase assay				Eur J Med Chem 167: 324-356 (2019) Article DOI: 10.1016/j.ejmech.2019.02.015 BindingDB Entry DOI: 10.7270/Q2CR5XPN
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11162 ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of human DPP-4 using H-Gly-Pro-para-Nitroanilide as substrate incubated for 20 mins prior to substrate addition measured after 30 mins by ...				Bioorg Med Chem Lett 24: 3447-51 (2014) Article DOI: 10.1016/j.bmcl.2014.05.076 BindingDB Entry DOI: 10.7270/Q2V69M60
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50095203 (CHEMBL94751 \| [(S)-6-(3-Benzhydryl-6-oxo-6H-pyrida...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregation				Eur J Med Chem 123: 256-281 (2016) Article DOI: 10.1016/j.ejmech.2016.07.061 BindingDB Entry DOI: 10.7270/Q2Q81G2Z
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50046172 (CHEMBL3310986) Show SMILES Cn1c2ccccc2c(O)c(c1=O)C(C)(NN)Nc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of human DPP-4 using H-Gly-Pro-para-Nitroanilide as substrate incubated for 20 mins prior to substrate addition measured after 30 mins by ...				Bioorg Med Chem Lett 24: 3447-51 (2014) Article DOI: 10.1016/j.bmcl.2014.05.076 BindingDB Entry DOI: 10.7270/Q2V69M60
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM233052 (3-(2,6-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM233053 (3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM233050 (3-(2-Chlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50046173 (CHEMBL3310987) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of human DPP-4 using H-Gly-Pro-para-Nitroanilide as substrate incubated for 20 mins prior to substrate addition measured after 30 mins by ...				Bioorg Med Chem Lett 24: 3447-51 (2014) Article DOI: 10.1016/j.bmcl.2014.05.076 BindingDB Entry DOI: 10.7270/Q2V69M60
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM233051 (3-(4-Fluorobenzylidene)-5-(4-isobutylphenyl)-2(3H)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50191201 (CHEMBL3978955) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassay				Eur J Med Chem 120: 170-201 (2016) Article DOI: 10.1016/j.ejmech.2016.04.077 BindingDB Entry DOI: 10.7270/Q2M32XQK
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50191273 (CHEMBL3908604) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassay				Eur J Med Chem 120: 170-201 (2016) Article DOI: 10.1016/j.ejmech.2016.04.077 BindingDB Entry DOI: 10.7270/Q2M32XQK
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50046174 (CHEMBL3310988) Show SMILES Br.Cc1ccc(=N)n(Cc2cccc(F)c2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of human DPP-4 using H-Gly-Pro-para-Nitroanilide as substrate incubated for 20 mins prior to substrate addition measured after 30 mins by ...				Bioorg Med Chem Lett 24: 3447-51 (2014) Article DOI: 10.1016/j.bmcl.2014.05.076 BindingDB Entry DOI: 10.7270/Q2V69M60
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM233052 (3-(2,6-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM233053 (3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM233050 (3-(2-Chlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM233051 (3-(4-Fluorobenzylidene)-5-(4-isobutylphenyl)-2(3H)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard					Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to...				J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J
Jamia Hamdard					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50191273 (CHEMBL3908604) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassay				Eur J Med Chem 120: 170-201 (2016) Article DOI: 10.1016/j.ejmech.2016.04.077 BindingDB Entry DOI: 10.7270/Q2M32XQK
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50191201 (CHEMBL3978955) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of recombinant ovine COX1 assessed as reduction in PGF2alpha production from PGH2 by enzyme immunoassay				Eur J Med Chem 120: 170-201 (2016) Article DOI: 10.1016/j.ejmech.2016.04.077 BindingDB Entry DOI: 10.7270/Q2M32XQK
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50099657 (CHEMBL3310990) Show SMILES N=CC(C(=O)c1ccccc1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard Curated by ChEMBL					Assay Description Inhibition of human DPP-4 using H-Gly-Pro-para-Nitroanilide as substrate incubated for 20 mins prior to substrate addition measured after 30 mins by ...				Bioorg Med Chem Lett 24: 3447-51 (2014) Article DOI: 10.1016/j.bmcl.2014.05.076 BindingDB Entry DOI: 10.7270/Q2V69M60
Jamia Hamdard Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50611819 (CHEMBL5282889) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50611819 (CHEMBL5282889) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair