Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stimulator of interferon genes protein (Human) | BDBM50509396![]() (CHEMBL4540223) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509397![]() (CHEMBL4566128) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509398![]() (CHEMBL4438957) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509399![]() (CHEMBL4468010) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509400![]() (CHEMBL4444544) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509397![]() (CHEMBL4566128) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509401![]() (CHEMBL4449584) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 7.01E+4 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509402![]() (CHEMBL4446841) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509403![]() (CHEMBL4526526 | US11453697, Example 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.37E+4 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509404![]() (CHEMBL4544112) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509403![]() (CHEMBL4526526 | US11453697, Example 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509405![]() (CHEMBL4573882) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50436163![]() (CHEMBL1231573) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509406![]() (CHEMBL4435159) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509407![]() (CHEMBL4573074) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50506263![]() (CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509408![]() (CHEMBL4459563) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509396![]() (CHEMBL4540223) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509409![]() (CHEMBL4578839 | US11453697, Example 43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509404![]() (CHEMBL4544112) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509410![]() (CHEMBL4517384) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509411![]() (CHEMBL4552089) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509412![]() (CHEMBL4474321 | US11453697, Example 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509413![]() (CHEMBL4439796) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509403![]() (CHEMBL4526526 | US11453697, Example 31) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509410![]() (CHEMBL4517384) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509414![]() (CHEMBL4586305) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509415![]() (CHEMBL4462144 | US11453697, Example 59) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509416![]() (CHEMBL4466863) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509417![]() (CHEMBL4566810 | US11453697, Example 55) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509418![]() (CHEMBL4588248) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509411![]() (CHEMBL4552089) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509419![]() (CHEMBL4539147) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509420![]() (CHEMBL4556336) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 420 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509398![]() (CHEMBL4438957) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509398![]() (CHEMBL4438957) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50506263![]() (CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509406![]() (CHEMBL4435159) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509401![]() (CHEMBL4449584) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509421![]() (CHEMBL4577528) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509399![]() (CHEMBL4468010) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509422![]() (CHEMBL4476079) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509408![]() (CHEMBL4459563) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509423![]() (CHEMBL4445083) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509424![]() (CHEMBL4441395 | US11453697, Example 48) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509400![]() (CHEMBL4444544) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 600 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509425![]() (CHEMBL4566174 | US11453697, Example 27) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509413![]() (CHEMBL4439796) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 960 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509396![]() (CHEMBL4540223) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stimulator of interferon genes protein (Human) | BDBM50509426![]() (CHEMBL4553050) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.28E+4 | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and Gilead Sciences Research Centre at IOCB Curated by ChEMBL | Assay Description Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-... | J Med Chem 62: 10676-10690 (2019) Article DOI: 10.1021/acs.jmedchem.9b01062 BindingDB Entry DOI: 10.7270/Q2TF01NG | |||||||||||
More data for this Ligand-Target Pair |
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