Compile Data Set for Download or QSAR

Found 40 hits with Last Name = 'appollina' and Initial = 'ma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037795 (CHEMBL120885 | Furan-2-carboxylic acid hydroxy-[1-...) Show SMILES CC(N(O)C(=O)c1ccco1)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C21H17NO4/c1-14(22(24)21(23)19-8-5-11-25-19)16-9-10-18-17(12-16)13-20(26-18)15-6-3-2-4-7-15/h2-14,24H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037791 (4-(Hydroxy-{1-[2-(3,4,5-trimethoxy-phenyl)-benzofu...) Show SMILES COC(=O)CCCC(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C25H29NO8/c1-15(26(29)23(27)7-6-8-24(28)32-4)16-9-10-19-17(11-16)12-20(34-19)18-13-21(30-2)25(33-5)22(14-18)31-3/h9-15,29H,6-8H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037805 (CHEMBL121025 | N-hydroxy-N-[1-[2-(3,4,5-trimethoxy...) Show SMILES COc1cc(cc(OC)c1OC)-c1cc2cc(ccc2o1)C(C)N(O)C(N)=O Show InChI InChI=1S/C20H22N2O6/c1-11(22(24)20(21)23)12-5-6-15-13(7-12)8-16(28-15)14-9-17(25-2)19(27-4)18(10-14)26-3/h5-11,24H,1-4H3,(H2,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037807 (CHEMBL331626 | N-[1-(2-Butyl-benzofuran-5-yl)-ethy...) Show SMILES CCCCc1cc2cc(ccc2o1)C(C)N(O)C(C)=O Show InChI InChI=1S/C16H21NO3/c1-4-5-6-15-10-14-9-13(7-8-16(14)20-15)11(2)17(19)12(3)18/h7-11,19H,4-6H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037803 (4-{[1-(2-Butyl-benzofuran-5-yl)-ethyl]-hydroxy-car...) Show SMILES CCCCc1cc2cc(ccc2o1)C(C)N(O)C(=O)CCCC(=O)OC Show InChI InChI=1S/C20H27NO5/c1-4-5-7-17-13-16-12-15(10-11-18(16)26-17)14(2)21(24)19(22)8-6-9-20(23)25-3/h10-14,24H,4-9H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037792 (CHEMBL122955 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) Show SMILES CCOC(=O)CCC(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C22H23NO5/c1-3-27-22(25)12-11-21(24)23(26)15(2)17-9-10-19-18(13-17)14-20(28-19)16-7-5-4-6-8-16/h4-10,13-15,26H,3,11-12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037793 (4-{Hydroxy-[1-(2-phenyl-benzofuran-5-yl)-ethyl]-ca...) Show SMILES COC(=O)CCCC(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C22H23NO5/c1-15(23(26)21(24)9-6-10-22(25)27-2)17-11-12-19-18(13-17)14-20(28-19)16-7-4-3-5-8-16/h3-5,7-8,11-15,26H,6,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037788 (CHEMBL421255 | N-Hydroxy-N-{1-[2-(6-methoxy-naphth...) Show SMILES COc1ccc2cc(ccc2c1)-c1cc2cc(ccc2o1)C(C)N(O)C(C)=O Show InChI InChI=1S/C23H21NO4/c1-14(24(26)15(2)25)16-7-9-22-20(10-16)13-23(28-22)19-5-4-18-12-21(27-3)8-6-17(18)11-19/h4-14,26H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037801 (4-{[1-(2-Decyl-benzofuran-5-yl)-ethyl]-hydroxy-car...) Show SMILES CCCCCCCCCCc1cc2cc(ccc2o1)C(C)N(O)C(=O)CCCC(=O)OC Show InChI InChI=1S/C26H39NO5/c1-4-5-6-7-8-9-10-11-13-23-19-22-18-21(16-17-24(22)32-23)20(2)27(30)25(28)14-12-15-26(29)31-3/h16-20,30H,4-15H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037796 (Acetic acid {hydroxy-[1-(2-phenyl-benzofuran-5-yl)...) Show SMILES CC(N(O)C(=O)COC(C)=O)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C20H19NO5/c1-13(21(24)20(23)12-25-14(2)22)16-8-9-18-17(10-16)11-19(26-18)15-6-4-3-5-7-15/h3-11,13,24H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037789 (CHEMBL332395 | N-Hydroxy-2-methoxy-N-[1-(2-phenyl-...) Show SMILES COCC(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H19NO4/c1-13(20(22)19(21)12-23-2)15-8-9-17-16(10-15)11-18(24-17)14-6-4-3-5-7-14/h3-11,13,22H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037797 (CHEMBL123396 | N-Hydroxy-3,4-dimethoxy-N-[1-(2-phe...) Show SMILES COc1ccc(cc1OC)C(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C25H23NO5/c1-16(26(28)25(27)19-10-12-22(29-2)24(14-19)30-3)18-9-11-21-20(13-18)15-23(31-21)17-7-5-4-6-8-17/h4-16,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037806 (CHEMBL123177 | Thiophene-2-carboxylic acid hydroxy...) Show SMILES CC(N(O)C(=O)c1cccs1)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C21H17NO3S/c1-14(22(24)21(23)20-8-5-11-26-20)16-9-10-18-17(12-16)13-19(25-18)15-6-3-2-4-7-15/h2-14,24H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037794 (CHEMBL331060 | N-Hydroxy-N-{1-[2-(3,4,5-trimethoxy...) Show SMILES COc1cc(cc(OC)c1OC)-c1cc2cc(ccc2o1)C(C)N(O)C(C)=O Show InChI InChI=1S/C21H23NO6/c1-12(22(24)13(2)23)14-6-7-17-15(8-14)9-18(28-17)16-10-19(25-3)21(27-5)20(11-16)26-4/h6-12,24H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022683 (CHEMBL418304 | N-[1-(4-Benzyloxy-phenyl)-ethyl]-N-...) Show SMILES CC(N(O)C(C)=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H19NO3/c1-13(18(20)14(2)19)16-8-10-17(11-9-16)21-12-15-6-4-3-5-7-15/h3-11,13,20H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037799 (CHEMBL123649 | N-Hydroxy-N-[1-(4-phenethyloxy-phen...) Show SMILES CC(N(O)C(C)=O)c1ccc(OCCc2ccccc2)cc1 Show InChI InChI=1S/C18H21NO3/c1-14(19(21)15(2)20)17-8-10-18(11-9-17)22-13-12-16-6-4-3-5-7-16/h3-11,14,21H,12-13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037790 (CHEMBL331881 | N-[1-(2-Decyl-benzofuran-5-yl)-ethy...) Show SMILES CCCCCCCCCCc1cc2cc(ccc2o1)C(C)N(O)C(C)=O Show InChI InChI=1S/C22H33NO3/c1-4-5-6-7-8-9-10-11-12-21-16-20-15-19(13-14-22(20)26-21)17(2)23(25)18(3)24/h13-17,25H,4-12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037798 (CHEMBL121390 | N-hydroxy-N-[1-(2-phinyl-5-benzofur...) Show SMILES CC(N(O)C(N)=O)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C17H16N2O3/c1-11(19(21)17(18)20)13-7-8-15-14(9-13)10-16(22-15)12-5-3-2-4-6-12/h2-11,21H,1H3,(H2,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037787 (CHEMBL332814 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) Show SMILES CC(N(O)C(C)=O)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C18H17NO3/c1-12(19(21)13(2)20)15-8-9-17-16(10-15)11-18(22-17)14-6-4-3-5-7-14/h3-12,21H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022697 (CHEMBL62114 | N-Hydroxy-N-{1-[4-(1-phenyl-ethoxy)-...) Show SMILES CC(Oc1ccc(cc1)C(C)N(O)C(C)=O)c1ccccc1 Show InChI InChI=1S/C18H21NO3/c1-13(19(21)15(3)20)16-9-11-18(12-10-16)22-14(2)17-7-5-4-6-8-17/h4-14,21H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037804 (2,N-Dihydroxy-N-[1-(2-phenyl-benzofuran-5-yl)-ethy...) Show SMILES CC(N(O)C(=O)CO)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C18H17NO4/c1-12(19(22)18(21)11-20)14-7-8-16-15(9-14)10-17(23-16)13-5-3-2-4-6-13/h2-10,12,20,22H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037802 (CHEMBL120107 | N-Hydroxy-2,6-dimethoxy-N-[1-(2-phe...) Show SMILES COc1cccc(OC)c1C(=O)N(O)C(C)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C25H23NO5/c1-16(26(28)25(27)24-21(29-2)10-7-11-22(24)30-3)18-12-13-20-19(14-18)15-23(31-20)17-8-5-4-6-9-17/h4-16,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037800 (CHEMBL121555 | N-Hydroxy-N-[1-(2-phenyl-benzofuran...) Show SMILES CC(N(O)C(=O)c1ccccc1)c1ccc2oc(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H19NO3/c1-16(24(26)23(25)18-10-6-3-7-11-18)19-12-13-21-20(14-19)15-22(27-21)17-8-4-2-5-9-17/h2-16,26H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay				J Med Chem 37: 3663-7 (1994) BindingDB Entry DOI: 10.7270/Q27943Q2
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226906 (CHEMBL30001) Show SMILES COc1cc2nc(O)nc(Cc3ccccc3)c2cc1OC Show InChI InChI=1S/C17H16N2O3/c1-21-15-9-12-13(8-11-6-4-3-5-7-11)18-17(20)19-14(12)10-16(15)22-2/h3-7,9-10H,8H2,1-2H3,(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226909 (CHEMBL31133) Show SMILES COc1cc2nc(O)nc(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C16H14N2O3/c1-20-13-8-11-12(9-14(13)21-2)17-16(19)18-15(11)10-6-4-3-5-7-10/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226910 (Bemarinone) Show SMILES COc1ccc2[nH]c(=O)nc(C)c2c1OC Show InChI InChI=1S/C11H12N2O3/c1-6-9-7(13-11(14)12-6)4-5-8(15-2)10(9)16-3/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 0.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226905 (CHEMBL1743762) Show SMILES Br.Cc1nc(O)nc2ccc(O)c(O)c12 Show InChI InChI=1S/C9H8N2O3/c1-4-7-5(11-9(14)10-4)2-3-6(12)8(7)13/h2-3,12-13H,1H3,(H,10,11,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226908 (CHEMBL30387) Show SMILES CCc1nc(O)nc2ccc(OC)c(OC)c12 Show InChI InChI=1S/C12H14N2O3/c1-4-7-10-8(14-12(15)13-7)5-6-9(16-2)11(10)17-3/h5-6H,4H2,1-3H3,(H,13,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226907 (CHEMBL30636) Show SMILES COc1cc2nc(O)nc(C3CCCC3)c2cc1OC Show InChI InChI=1S/C15H18N2O3/c1-19-12-7-10-11(8-13(12)20-2)16-15(18)17-14(10)9-5-3-4-6-9/h7-9H,3-6H2,1-2H3,(H,16,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226913 (CHEMBL30542) Show SMILES COc1cc(OC)c2c(C)nc(O)nc2c1 Show InChI InChI=1S/C11H12N2O3/c1-6-10-8(13-11(14)12-6)4-7(15-2)5-9(10)16-3/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226912 (CHEMBL284443) Show SMILES CN(C)c1ccc2nc(O)nc(C)c2c1 Show InChI InChI=1S/C11H13N3O/c1-7-9-6-8(14(2)3)4-5-10(9)13-11(15)12-7/h4-6H,1-3H3,(H,12,13,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226914 (CHEMBL30607) Show SMILES COc1cc2nc(O)nc(C(C)C)c2cc1OC Show InChI InChI=1S/C13H16N2O3/c1-7(2)12-8-5-10(17-3)11(18-4)6-9(8)14-13(16)15-12/h5-7H,1-4H3,(H,14,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM34651 (Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226903 (CHEMBL30699) Show SMILES COc1cc2nc(O)nc(C)c2cc1OC Show InChI InChI=1S/C11H12N2O3/c1-6-7-4-9(15-2)10(16-3)5-8(7)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226915 (CHEMBL284798) Show SMILES COc1cc2nc(O)nc(c2cc1OC)C(F)(F)F Show InChI InChI=1S/C11H9F3N2O3/c1-18-7-3-5-6(4-8(7)19-2)15-10(17)16-9(5)11(12,13)14/h3-4H,1-2H3,(H,15,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226904 (CHEMBL30629) Show SMILES COc1ccc(OC)c2c(C)nc(O)nc12 Show InChI InChI=1S/C11H12N2O3/c1-6-9-7(15-2)4-5-8(16-3)10(9)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226916 (CHEMBL281242) Show SMILES Cc1nc(O)nc2ccccc12 Show InChI InChI=1S/C9H8N2O/c1-6-7-4-2-3-5-8(7)11-9(12)10-6/h2-5H,1H3,(H,10,11,12)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226911 (CHEMBL30541) Show SMILES COc1cc(OC)c2nc(O)nc(C)c2c1 Show InChI InChI=1S/C11H12N2O3/c1-6-8-4-7(15-2)5-9(16-3)10(8)13-11(14)12-6/h4-5H,1-3H3,(H,12,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226902 (CHEMBL435758) Show SMILES CN1CCN(CC1)c1ccc2nc(O)nc(C)c2c1 Show InChI InChI=1S/C14H18N4O/c1-10-12-9-11(18-7-5-17(2)6-8-18)3-4-13(12)16-14(19)15-10/h3-4,9H,5-8H2,1-2H3,(H,15,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair