Found 287 hits with Last Name = 'chowdhury' and Initial = 'ma' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375397
(CHEMBL262849)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-8-6-12(7-9-14)4-5-13-3-2-10-15-11-13/h2-3,6-11H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| DrugBank PDB Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by EIA |
Bioorg Med Chem Lett 20: 5245-50 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.155 BindingDB Entry DOI: 10.7270/Q2RX9C9R |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank PDB Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 20: 4544-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.022 BindingDB Entry DOI: 10.7270/Q2X92BG8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375406
(CHEMBL259429)Show InChI InChI=1S/C14H12N2O2S/c1-11-3-2-10-16-14(11)9-6-12-4-7-13(8-5-12)19(15,17)18/h2-5,7-8,10H,1H3,(H2,15,17,18) | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| PDB Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50374775
(CHEMBL260841)Show SMILES CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C18H16BrNO7S/c1-28(24,25)16-8-2-13(3-9-16)12-17(14-4-6-15(19)7-5-14)18(21)26-10-11-27-20(22)23/h2-9,12H,10-11H2,1H3/b17-12+ | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| PDB Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem Lett 18: 6138-41 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.009 BindingDB Entry DOI: 10.7270/Q2SF2W16 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 9694-8 (2008)
Article DOI: 10.1016/j.bmc.2008.10.001 BindingDB Entry DOI: 10.7270/Q2PN95HK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
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| PDB Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 15: 6796-801 (2007)
Article DOI: 10.1016/j.bmc.2007.07.021 BindingDB Entry DOI: 10.7270/Q28052B9 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| DrugBank PDB Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immuno assay |
Bioorg Med Chem Lett 21: 3951-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.017 BindingDB Entry DOI: 10.7270/Q2J103HW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
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| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 19: 3014-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.059 BindingDB Entry DOI: 10.7270/Q2CR5T81 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375403
(CHEMBL260944)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-5-3-2-4-13(14)7-6-12-8-10-15-11-9-12/h2-5,8-11H,1H3 | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem 17: 5182-8 (2009)
Article DOI: 10.1016/j.bmc.2009.05.046 BindingDB Entry DOI: 10.7270/Q2DF6S5V |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| DrugBank PDB Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immunoassay |
J Med Chem 52: 1525-9 (2009)
Article DOI: 10.1021/jm8015188 BindingDB Entry DOI: 10.7270/Q26Q1X5H |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| DrugBank PDB Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immuno assay |
Bioorg Med Chem Lett 19: 584-8 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.066 BindingDB Entry DOI: 10.7270/Q22R3RJ7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| DrugBank PDB Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immunoassay |
Bioorg Med Chem Lett 20: 1324-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.014 BindingDB Entry DOI: 10.7270/Q2GQ6XVV |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
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| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX-1 |
J Med Chem 54: 1356-64 (2011)
Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50374768
(CHEMBL260539)Show SMILES CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccccc2)cc1 Show InChI InChI=1S/C18H17NO7S/c1-27(23,24)16-9-7-14(8-10-16)13-17(15-5-3-2-4-6-15)18(20)25-11-12-26-19(21)22/h2-10,13H,11-12H2,1H3/b17-13+ | PDB MMDB
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| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50339185
((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)Show InChI InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 | PDB
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| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX-1 |
J Med Chem 54: 1356-64 (2011)
Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50248696
(1-(4-Methanesulfonylphenyl)-5-(2-chloropyridin-4-y...)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccnc(Cl)c1)C(F)(F)F Show InChI InChI=1S/C16H11ClF3N3O2S/c1-26(24,25)12-4-2-11(3-5-12)23-13(9-14(22-23)16(18,19)20)10-6-7-21-15(17)8-10/h2-9H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immunoassay |
J Med Chem 52: 1525-9 (2009)
Article DOI: 10.1021/jm8015188 BindingDB Entry DOI: 10.7270/Q26Q1X5H |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375401
(CHEMBL260943)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-7-4-5-12(11-14)8-9-13-6-2-3-10-15-13/h2-7,10-11H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375405
(CHEMBL404928)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-8-3-2-6-12(14)9-10-13-7-4-5-11-15-13/h2-8,11H,1H3 | PDB MMDB
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| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375403
(CHEMBL260944)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-5-3-2-4-13(14)7-6-12-8-10-15-11-9-12/h2-5,8-11H,1H3 | PDB
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| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375405
(CHEMBL404928)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-8-3-2-6-12(14)9-10-13-7-4-5-11-15-13/h2-8,11H,1H3 | PDB
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UniProtKB/SwissProt
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| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Lipoxygenase
(Solanum tuberosum (potato)) | BDBM50303170
(CHEMBL579022 | N-Acetyl-5-(N-difluoromethyl-1,2-di...)Show SMILES CC(=O)NS(=O)(=O)c1cc(ccc1C(O)=O)-c1ccn(C(F)F)c(=O)c1 Show InChI InChI=1S/C15H12F2N2O6S/c1-8(20)18-26(24,25)12-6-9(2-3-11(12)14(22)23)10-4-5-19(15(16)17)13(21)7-10/h2-7,15H,1H3,(H,18,20)(H,22,23) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of potato 5-LOX after 5 mins by enzyme immuno assay |
Bioorg Med Chem Lett 19: 6855-61 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.083 BindingDB Entry DOI: 10.7270/Q2D79CB6 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 9694-8 (2008)
Article DOI: 10.1016/j.bmc.2008.10.001 BindingDB Entry DOI: 10.7270/Q2PN95HK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 20: 1324-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.014 BindingDB Entry DOI: 10.7270/Q2GQ6XVV |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375395
(CHEMBL265444)Show InChI InChI=1S/C13H10N2O2S/c14-18(16,17)13-8-5-11(6-9-13)4-7-12-3-1-2-10-15-12/h1-3,5-6,8-10H,(H2,14,16,17) | PDB MMDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of sheep COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 20: 4544-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.022 BindingDB Entry DOI: 10.7270/Q2X92BG8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem 17: 5182-8 (2009)
Article DOI: 10.1016/j.bmc.2009.05.046 BindingDB Entry DOI: 10.7270/Q2DF6S5V |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem Lett 19: 3014-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.059 BindingDB Entry DOI: 10.7270/Q2CR5T81 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375399
(CHEMBL262852)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-4-2-3-13(11-14)6-5-12-7-9-15-10-8-12/h2-4,7-11H,1H3 | PDB MMDB
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| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Lipoxygenase
(Solanum tuberosum (potato)) | BDBM50303169
(CHEMBL571852 | N-Acetyl-4-(N-difluoromethyl-1,2-di...)Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1C(O)=O)-c1ccn(C(F)F)c(=O)c1 Show InChI InChI=1S/C15H12F2N2O6S/c1-8(20)18-26(24,25)12-3-2-9(6-11(12)14(22)23)10-4-5-19(15(16)17)13(21)7-10/h2-7,15H,1H3,(H,18,20)(H,22,23) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of potato 5-LOX after 5 mins by enzyme immuno assay |
Bioorg Med Chem Lett 19: 6855-61 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.083 BindingDB Entry DOI: 10.7270/Q2D79CB6 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375398
(CHEMBL408370)Show InChI InChI=1S/C14H11NO2S/c1-18(16,17)14-9-6-12(7-10-14)5-8-13-4-2-3-11-15-13/h2-4,6-7,9-11H,1H3 | PDB MMDB
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| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Bos taurus) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of bovine COX-1 by enzyme immuno assay |
Bioorg Med Chem Lett 19: 6855-61 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.083 BindingDB Entry DOI: 10.7270/Q2D79CB6 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 15: 6796-801 (2007)
Article DOI: 10.1016/j.bmc.2007.07.021 BindingDB Entry DOI: 10.7270/Q28052B9 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem Lett 19: 584-8 (2009)
Article DOI: 10.1016/j.bmcl.2008.12.066 BindingDB Entry DOI: 10.7270/Q22R3RJ7 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
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| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immuno assay |
Bioorg Med Chem Lett 18: 6138-41 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.009 BindingDB Entry DOI: 10.7270/Q2SF2W16 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50374775
(CHEMBL260841)Show SMILES CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C18H16BrNO7S/c1-28(24,25)16-8-2-13(3-9-16)12-17(14-4-6-15(19)7-5-14)18(21)26-10-11-27-20(22)23/h2-9,12H,10-11H2,1H3/b17-12+ | PDB
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| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | |
Lipoxygenase
(Solanum tuberosum (potato)) | BDBM50303172
(5-(N-Difluoromethyl-1,2-dihydropyrid-2-one-4-yl)sa...)Show InChI InChI=1S/C13H9F2NO4/c14-13(15)16-4-3-8(6-11(16)18)7-1-2-10(17)9(5-7)12(19)20/h1-6,13,17H,(H,19,20) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of potato 5-LOX after 5 mins by enzyme immuno assay |
Bioorg Med Chem Lett 19: 6855-61 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.083 BindingDB Entry DOI: 10.7270/Q2D79CB6 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50374770
(CHEMBL407035)Show SMILES CS(=O)(=O)c1ccc(\C=C(\C(O)=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C16H13FO4S/c1-22(20,21)14-8-2-11(3-9-14)10-15(16(18)19)12-4-6-13(17)7-5-12/h2-10H,1H3,(H,18,19)/b15-10+ | PDB
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UniProtKB/SwissProt
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Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50339180
(2-{2-[1-(4-Chlorobenzoyl)-2-methyl-5-methoxyl-1H-i...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCCS(=O)(=O)NO)c2c1 Show InChI InChI=1S/C21H21ClN2O7S/c1-13-17(12-20(25)31-9-10-32(28,29)23-27)18-11-16(30-2)7-8-19(18)24(13)21(26)14-3-5-15(22)6-4-14/h3-8,11,23,27H,9-10,12H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX-2 |
J Med Chem 54: 1356-64 (2011)
Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM50375402
(CHEMBL404927)Show InChI InChI=1S/C15H13NO2S/c1-12-6-5-11-16-14(12)10-9-13-7-3-4-8-15(13)19(2,17)18/h3-8,11H,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM22369
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by enzyme immuno assay |
Bioorg Med Chem Lett 21: 3951-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.017 BindingDB Entry DOI: 10.7270/Q2J103HW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM22369
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 15: 6796-801 (2007)
Article DOI: 10.1016/j.bmc.2007.07.021 BindingDB Entry DOI: 10.7270/Q28052B9 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM22369
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immunoassay |
Bioorg Med Chem 16: 3302-8 (2008)
Article DOI: 10.1016/j.bmc.2007.12.006 BindingDB Entry DOI: 10.7270/Q2DN45XK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Ovis aries (Sheep)) | BDBM22369
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by ChEMBL
| Assay Description Inhibition of ovine COX2 by enzyme immuno assay |
Bioorg Med Chem 16: 1948-56 (2008)
Article DOI: 10.1016/j.bmc.2007.11.003 BindingDB Entry DOI: 10.7270/Q2VH5PPP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |