Found 60 hits with Last Name = 'boeck' and Initial = 'md' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402675
(CHEMBL2207348)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cnccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-8-9-26-15-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402675
(CHEMBL2207348)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cnccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-8-9-26-15-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50394620
(CHEMBL2164602)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H23ClN4O2/c24-19-6-8-21(9-7-19)30-22-5-1-3-18(15-22)17-27-11-13-28(14-12-27)23(29)26-20-4-2-10-25-16-20/h1-10,15-16H,11-14,17H2,(H,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402695
(CHEMBL2207356)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402692
(CHEMBL2207358)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccnc4nccn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(16-21)17-29-12-14-30(15-13-29)24(32)28-22-8-9-26-23-27-10-11-31(22)23/h1-11,16H,12-15,17H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402679
(CHEMBL2207344)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4[nH]ccc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-18(14-23)17-30-10-12-31(13-11-30)25(32)29-21-15-19-8-9-27-24(19)28-16-21/h1-9,14-16H,10-13,17H2,(H,27,28)(H,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402694
(CHEMBL2203328)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4cccnn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-6-8-20(9-7-19)33-21-4-1-3-18(15-21)17-29-11-13-30(14-12-29)24(32)28-23-16-26-22-5-2-10-27-31(22)23/h1-10,15-16H,11-14,17H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402685
(CHEMBL2207365)Show SMILES Clc1conc1NC(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 Show InChI InChI=1S/C21H20Cl2N4O3/c22-16-4-6-17(7-5-16)30-18-3-1-2-15(12-18)13-26-8-10-27(11-9-26)21(28)24-20-19(23)14-29-25-20/h1-7,12,14H,8-11,13H2,(H,24,25,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402695
(CHEMBL2207356)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402683
(CHEMBL2207340)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nsnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O2S/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50394629
(CHEMBL2164596 | US9169224, 60)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-9-11-22(12-10-20)30-23-8-4-5-19(17-23)18-27-13-15-28(16-14-27)24(29)26-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2,(H,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402680
(CHEMBL2207343)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cncc4ccccc34)c2)cc1 Show InChI InChI=1S/C27H25ClN4O2/c28-22-8-10-23(11-9-22)34-24-6-3-4-20(16-24)19-31-12-14-32(15-13-31)27(33)30-26-18-29-17-21-5-1-2-7-25(21)26/h1-11,16-18H,12-15,19H2,(H,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402681
(CHEMBL2207342)Show SMILES Cc1nc2cc(NC(=O)N3CCN(Cc4cccc(Oc5ccc(Cl)cc5)c4)CC3)ccc2o1 Show InChI InChI=1S/C26H25ClN4O3/c1-18-28-24-16-21(7-10-25(24)33-18)29-26(32)31-13-11-30(12-14-31)17-19-3-2-4-23(15-19)34-22-8-5-20(27)6-9-22/h2-10,15-16H,11-14,17H2,1H3,(H,29,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402689
(CHEMBL2207361)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-6-8-19(9-7-18)30-20-4-1-3-17(15-20)16-27-11-13-28(14-12-27)22(29)25-21-5-2-10-24-26-21/h1-10,15H,11-14,16H2,(H,25,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402677
(CHEMBL2207346)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ccccc34)c2)cc1 Show InChI InChI=1S/C25H23ClN4O3/c26-19-8-10-20(11-9-19)32-21-5-3-4-18(16-21)17-29-12-14-30(15-13-29)25(31)27-24-22-6-1-2-7-23(22)33-28-24/h1-11,16H,12-15,17H2,(H,27,28,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402680
(CHEMBL2207343)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cncc4ccccc34)c2)cc1 Show InChI InChI=1S/C27H25ClN4O2/c28-22-8-10-23(11-9-22)34-24-6-3-4-20(16-24)19-31-12-14-32(15-13-31)27(33)30-26-18-29-17-21-5-1-2-7-25(21)26/h1-11,16-18H,12-15,19H2,(H,30,33) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402690
(CHEMBL2207360)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnccn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-4-6-19(7-5-18)30-20-3-1-2-17(14-20)16-27-10-12-28(13-11-27)22(29)26-21-15-24-8-9-25-21/h1-9,14-15H,10-13,16H2,(H,25,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402677
(CHEMBL2207346)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ccccc34)c2)cc1 Show InChI InChI=1S/C25H23ClN4O3/c26-19-8-10-20(11-9-19)32-21-5-3-4-18(16-21)17-29-12-14-30(15-13-29)25(31)27-24-22-6-1-2-7-23(22)33-28-24/h1-11,16H,12-15,17H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402673
(CHEMBL2207350)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cccnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-23-22-21(33-28-23)5-2-10-26-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402676
(CHEMBL2207347)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ncccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-22-21-5-2-10-26-23(21)33-28-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
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UniChem
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PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402693
(CHEMBL2207357)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cc4nccn4cn3)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(14-21)16-29-10-12-30(13-11-29)24(32)28-22-15-23-26-8-9-31(23)17-27-22/h1-9,14-15,17H,10-13,16H2,(H,28,32) | PDB
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| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402685
(CHEMBL2207365)Show SMILES Clc1conc1NC(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 Show InChI InChI=1S/C21H20Cl2N4O3/c22-16-4-6-17(7-5-16)30-18-3-1-2-15(12-18)13-26-8-10-27(11-9-26)21(28)24-20-19(23)14-29-25-20/h1-7,12,14H,8-11,13H2,(H,24,25,28) | PDB
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PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402679
(CHEMBL2207344)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4[nH]ccc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-18(14-23)17-30-10-12-31(13-11-30)25(32)29-21-15-19-8-9-27-24(19)28-16-21/h1-9,14-16H,10-13,17H2,(H,27,28)(H,29,32) | PDB
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PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402673
(CHEMBL2207350)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cccnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-23-22-21(33-28-23)5-2-10-26-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
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UniChem
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PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402676
(CHEMBL2207347)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ncccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-6-8-19(9-7-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)27-22-21-5-2-10-26-23(21)33-28-22/h1-10,15H,11-14,16H2,(H,27,28,31) | PDB
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| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402692
(CHEMBL2207358)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccnc4nccn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(16-21)17-29-12-14-30(15-13-29)24(32)28-22-8-9-26-23-27-10-11-31(22)23/h1-11,16H,12-15,17H2,(H,28,32) | PDB
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PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402683
(CHEMBL2207340)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nsnc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O2S/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
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B.MOAD
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UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402686
(CHEMBL2207364)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccon3)c2)cc1 Show InChI InChI=1S/C21H21ClN4O3/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-25-9-11-26(12-10-25)21(27)23-20-8-13-28-24-20/h1-8,13-14H,9-12,15H2,(H,23,24,27) | PDB
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PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402684
(CHEMBL2207366)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nonc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
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| Article
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| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402688
(CHEMBL2207362)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn[nH]3)c2)cc1 Show InChI InChI=1S/C21H22ClN5O2/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-26-10-12-27(13-11-26)21(28)24-20-8-9-23-25-20/h1-9,14H,10-13,15H2,(H2,23,24,25,28) | PDB
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| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50394620
(CHEMBL2164602)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H23ClN4O2/c24-19-6-8-21(9-7-19)30-22-5-1-3-18(15-22)17-27-11-13-28(14-12-27)23(29)26-20-4-2-10-25-16-20/h1-10,15-16H,11-14,17H2,(H,26,29) | PDB
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CHEMBL
MCE
PC cid
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UniChem
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| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402697
(CHEMBL2207354)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn4ccnc4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-6-22(7-5-20)33-23-3-1-2-19(16-23)18-29-12-14-31(15-13-29)25(32)28-21-8-10-30-11-9-27-24(30)17-21/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
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PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402700
(CHEMBL2207351)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4ccccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-5-3-4-19(16-22)18-29-12-14-30(15-13-29)25(32)28-24-17-27-23-6-1-2-11-31(23)24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
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| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402687
(CHEMBL2207363)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3nnn[nH]3)c2)cc1 Show InChI InChI=1S/C19H20ClN7O2/c20-15-4-6-16(7-5-15)29-17-3-1-2-14(12-17)13-26-8-10-27(11-9-26)19(28)21-18-22-24-25-23-18/h1-7,12H,8-11,13H2,(H2,21,22,23,24,25,28) | PDB
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| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402694
(CHEMBL2203328)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4cccnn34)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-6-8-20(9-7-19)33-21-4-1-3-18(15-21)17-29-11-13-30(14-12-29)24(32)28-23-16-26-22-5-2-10-27-31(22)23/h1-10,15-16H,11-14,17H2,(H,28,32) | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402678
(CHEMBL2207345)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4cc[nH]c4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-19-4-6-21(7-5-19)33-22-3-1-2-18(14-22)17-30-10-12-31(13-11-30)25(32)29-20-15-24-23(28-16-20)8-9-27-24/h1-9,14-16,27H,10-13,17H2,(H,29,32) | PDB
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PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402689
(CHEMBL2207361)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccnn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-6-8-19(9-7-18)30-20-4-1-3-17(15-20)16-27-11-13-28(14-12-27)22(29)25-21-5-2-10-24-26-21/h1-10,15H,11-14,16H2,(H,25,26,29) | PDB
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PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402696
(CHEMBL2207355)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccc4nccn4c3)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-4-7-22(8-5-20)33-23-3-1-2-19(16-23)17-29-12-14-30(15-13-29)25(32)28-21-6-9-24-27-10-11-31(24)18-21/h1-11,16,18H,12-15,17H2,(H,28,32) | PDB
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PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402687
(CHEMBL2207363)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3nnn[nH]3)c2)cc1 Show InChI InChI=1S/C19H20ClN7O2/c20-15-4-6-16(7-5-15)29-17-3-1-2-14(12-17)13-26-8-10-27(11-9-26)19(28)21-18-22-24-25-23-18/h1-7,12H,8-11,13H2,(H2,21,22,23,24,25,28) | PDB
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| Article
PubMed
| n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402684
(CHEMBL2207366)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nonc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-7-9-19(10-8-18)32-20-4-1-3-17(15-20)16-29-11-13-30(14-12-29)24(31)26-21-5-2-6-22-23(21)28-33-27-22/h1-10,15H,11-14,16H2,(H,26,31) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402700
(CHEMBL2207351)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnc4ccccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-5-3-4-19(16-22)18-29-12-14-30(15-13-29)25(32)28-24-17-27-23-6-1-2-11-31(23)24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402691
(CHEMBL2207359)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn4ccnc4n3)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(16-21)17-29-12-14-31(15-13-29)24(32)28-22-8-10-30-11-9-26-23(30)27-22/h1-11,16H,12-15,17H2,(H,26,27,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402688
(CHEMBL2207362)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccn[nH]3)c2)cc1 Show InChI InChI=1S/C21H22ClN5O2/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-26-10-12-27(13-11-26)21(28)24-20-8-9-23-25-20/h1-9,14H,10-13,15H2,(H2,23,24,25,28) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402690
(CHEMBL2207360)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cnccn3)c2)cc1 Show InChI InChI=1S/C22H22ClN5O2/c23-18-4-6-19(7-5-18)30-20-3-1-2-17(14-20)16-27-10-12-28(13-11-27)22(29)26-21-15-24-8-9-25-21/h1-9,14-15H,10-13,16H2,(H,25,26,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402674
(CHEMBL2207349)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4ccncc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-15-26-9-8-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402681
(CHEMBL2207342)Show SMILES Cc1nc2cc(NC(=O)N3CCN(Cc4cccc(Oc5ccc(Cl)cc5)c4)CC3)ccc2o1 Show InChI InChI=1S/C26H25ClN4O3/c1-18-28-24-16-21(7-10-25(24)33-18)29-26(32)31-13-11-30(12-14-31)17-19-3-2-4-23(15-19)34-22-8-5-20(27)6-9-22/h2-10,15-16H,11-14,17H2,1H3,(H,29,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50394629
(CHEMBL2164596 | US9169224, 60)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccccc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-9-11-22(12-10-20)30-23-8-4-5-19(17-23)18-27-13-15-28(16-14-27)24(29)26-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2,(H,26,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50402698
(CHEMBL2207353)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccn4ccnc34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-6-8-21(9-7-20)33-22-4-1-3-19(17-22)18-29-13-15-31(16-14-29)25(32)28-23-5-2-11-30-12-10-27-24(23)30/h1-12,17H,13-16,18H2,(H,28,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of human FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402693
(CHEMBL2207357)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cc4nccn4cn3)c2)cc1 Show InChI InChI=1S/C24H23ClN6O2/c25-19-4-6-20(7-5-19)33-21-3-1-2-18(14-21)16-29-10-12-30(13-11-29)24(32)28-22-15-23-26-8-9-31(23)17-27-22/h1-9,14-15,17H,10-13,16H2,(H,28,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50402686
(CHEMBL2207364)Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccon3)c2)cc1 Show InChI InChI=1S/C21H21ClN4O3/c22-17-4-6-18(7-5-17)29-19-3-1-2-16(14-19)15-25-9-11-26(12-10-25)21(27)23-20-8-13-28-24-20/h1-8,13-14H,9-12,15H2,(H,23,24,27) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development, LLC
Curated by ChEMBL
| Assay Description
Inhibition of rat FAAH preincubated for 60 mins |
Bioorg Med Chem Lett 22: 7357-62 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.076
BindingDB Entry DOI: 10.7270/Q28S4R30 |
More data for this
Ligand-Target Pair | |
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