Compile Data Set for Download or QSAR

Found 7 hits with Last Name = 'ames' and Initial = 'mm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CAD protein (Homo sapiens (Human))	BDBM50010599 (6-Mercaptomethyl-2-oxo-2,3,4,5-tetrahydro-pyrimidi...) Show SMILES OC(=O)C1CC(NC(=O)N1)C=S Show InChI InChI=1S/C6H8N2O3S/c9-5(10)4-1-3(2-12)7-6(11)8-4/h2-4H,1H2,(H,9,10)(H2,7,8,11)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5				J Med Chem 33: 819-23 (1990) BindingDB Entry DOI: 10.7270/Q2ZC81VR
					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50010600 (CHEMBL168878 | Ethyl-3-borono-2-(carbamylamino)pro...) Show SMILES CCOC(=O)C(CB(O)O)NC(N)=O Show InChI InChI=1S/C6H13BN2O5/c1-2-14-5(10)4(3-7(12)13)9-6(8)11/h4,12-13H,2-3H2,1H3,(H3,8,9,11)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 6.0				J Med Chem 33: 819-23 (1990) BindingDB Entry DOI: 10.7270/Q2ZC81VR
					More data for this Ligand-Target Pair
Aromatic-L-amino-acid decarboxylase (Mus musculus)	BDBM50046351 (2-Amino-2-fluoromethyl-3-(5-hydroxy-1H-indol-3-yl)...) Show SMILES N[C@@](CF)(Cc1c[nH]c2ccc(O)cc12)C(O)=O Show InChI InChI=1S/C12H13FN2O3/c13-6-12(14,11(17)18)4-7-5-15-10-2-1-8(16)3-9(7)10/h1-3,5,15-16H,4,6,14H2,(H,17,18)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic and Foundation Curated by ChEMBL					Assay Description Dissociation constant (KI) of the compound was evaluated as inhibitor of murine liver aromatic L-amino acid decarboxylase (AADC)				J Med Chem 36: 305-13 (1993) BindingDB Entry DOI: 10.7270/Q2DV1J0Z
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50073857 (3,9-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethyl...) Show SMILES OCC1OC(C(O)C(O)C1O)n1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c3c4cc(O)ccc4[nH]c3c12 Show InChI InChI=1S/C26H21N3O9/c30-7-14-21(33)22(34)23(35)26(38-14)29-13-4-2-9(32)6-11(13)16-18-17(24(36)28-25(18)37)15-10-5-8(31)1-3-12(10)27-19(15)20(16)29/h1-6,14,21-23,26-27,30-35H,7H2,(H,28,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
MediChem Research, Inc. Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)				Bioorg Med Chem Lett 9: 145-50 (1999) BindingDB Entry DOI: 10.7270/Q2571B6S
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50073854 (2,10-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...) Show SMILES OCC1OC(C(O)C(O)C1O)n1c2cc(O)ccc2c2c3C(=O)NC(=O)c3c3c4ccc(O)cc4[nH]c3c12 Show InChI InChI=1S/C26H21N3O9/c30-7-14-21(33)22(34)23(35)26(38-14)29-13-6-9(32)2-4-11(13)16-18-17(24(36)28-25(18)37)15-10-3-1-8(31)5-12(10)27-19(15)20(16)29/h1-6,14,21-23,26-27,30-35H,7H2,(H,28,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
MediChem Research, Inc. Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)				Bioorg Med Chem Lett 9: 145-50 (1999) BindingDB Entry DOI: 10.7270/Q2571B6S
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50073855 (1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...) Show SMILES OCC1OC(C(O)C(O)C1O)n1c2c(O)cccc2c2c3C(=O)NC(=O)c3c3c4cccc(O)c4[nH]c3c12 Show InChI InChI=1S/C26H21N3O9/c30-7-12-21(33)22(34)23(35)26(38-12)29-19-9(4-2-6-11(19)32)14-16-15(24(36)28-25(16)37)13-8-3-1-5-10(31)17(8)27-18(13)20(14)29/h1-6,12,21-23,26-27,30-35H,7H2,(H,28,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
MediChem Research, Inc. Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)				Bioorg Med Chem Lett 9: 145-50 (1999) BindingDB Entry DOI: 10.7270/Q2571B6S
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50073856 (4,8-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethyl...) Show SMILES OCC1OC(C(O)C(O)C1O)n1c2cccc(O)c2c2c3C(=O)NC(=O)c3c3c([nH]c4cccc(O)c34)c12 Show InChI InChI=1S/C26H21N3O9/c30-7-12-21(33)22(34)23(35)26(38-12)29-9-4-2-6-11(32)14(9)16-18-17(24(36)28-25(18)37)15-13-8(3-1-5-10(13)31)27-19(15)20(16)29/h1-6,12,21-23,26-27,30-35H,7H2,(H,28,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
MediChem Research, Inc. Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)				Bioorg Med Chem Lett 9: 145-50 (1999) BindingDB Entry DOI: 10.7270/Q2571B6S
					More data for this Ligand-Target Pair