BindingDB PrimarySearch

Found 9 hits with Last Name = 'tute' and Initial = 'ms'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosin				J Med Chem 31: 1036-9 (1988) BindingDB Entry DOI: 10.7270/Q2639RZK
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM96939 ((4-amino-6,7-dimethoxy-quinazolin-2-yl)-dimethyl-a...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosin				J Med Chem 31: 1036-9 (1988) BindingDB Entry DOI: 10.7270/Q2639RZK
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50227377 (CHEMBL414822) Show SMILES COc1cc2nc(cc(N)c2cc1OC)N(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosin				J Med Chem 31: 1036-9 (1988) BindingDB Entry DOI: 10.7270/Q2639RZK
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50227382 (CHEMBL8588) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosin				J Med Chem 31: 1036-9 (1988) BindingDB Entry DOI: 10.7270/Q2639RZK
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to alpha-2 adrenergic receptor by displacement of [3H]clonidine				J Med Chem 31: 1036-9 (1988) BindingDB Entry DOI: 10.7270/Q2639RZK
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50287481 (3-[5-(4-Fluoro-benzenesulfonylamino)-3-imidazol-1-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human platelet microsomal TXA2 synthase				Bioorg Med Chem Lett 6: 1691-1696 (1996) Article DOI: 10.1016/0960-894X(96)00299-5 BindingDB Entry DOI: 10.7270/Q27P8ZBS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000317 (3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...) Show SMILES Cc1c(Cn2ccnc2)c2ccccc2n1CCC(O)=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human platelet microsomal TXA2 synthase				Bioorg Med Chem Lett 6: 1691-1696 (1996) Article DOI: 10.1016/0960-894X(96)00299-5 BindingDB Entry DOI: 10.7270/Q27P8ZBS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50060378 (3-[5-(4-Fluoro-benzenesulfonylamino)-3-imidazol-1-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human platelet microsomal TXA2 synthase				Bioorg Med Chem Lett 6: 1691-1696 (1996) Article DOI: 10.1016/0960-894X(96)00299-5 BindingDB Entry DOI: 10.7270/Q27P8ZBS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50060380 (3-[5-(4-Fluoro-benzenesulfonylamino)-3-pyridin-3-y...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human platelet microsomal TXA2 synthase				Bioorg Med Chem Lett 6: 1691-1696 (1996) Article DOI: 10.1016/0960-894X(96)00299-5 BindingDB Entry DOI: 10.7270/Q27P8ZBS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair