BindingDB PrimarySearch

Found 15 hits with Last Name = 'tasker' and Initial = 'nr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM50535759 (CHEMBL4471843) Show SMILES O=C1NC(=O)C(=O)c2sc(cc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incub...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 1 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A1 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A2 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 \| US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A3 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 1 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 \| US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A1 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM50059084 (CHEMBL3393171 \| US10308663, Thienopyridone (5)) Show SMILES Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A3 (unknown origin)				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 2 (Homo sapiens (Human))	BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A2 (unknown origin)				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 1 (Homo sapiens (Human))	BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) Show SMILES NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A1 (unknown origin)				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM50237949 (2-(5-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM50535760 (CHEMBL4466901) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human))	BDBM50237948 ((E)-2-(2-(5-(4-chlorophenyl)furan-2-yl)vinyl)-6-me...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubat...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Protein tyrosine phosphatase type IVA 1 (Homo sapiens (Human))	BDBM50535761 (CHEMBL4539375) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of PTP4A1 (unknown origin)				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM396097 (US10308663, JMS-631-053) Show SMILES N=C1c2sc(cc2C(=O)NC1=O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of human PTP1B assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mins in presence of DTT by Fluorescence base...				Bioorg Med Chem Lett 29: 2008-2015 (2019) Article DOI: 10.1016/j.bmcl.2019.06.048 BindingDB Entry DOI: 10.7270/Q2VH5SBF
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair