| Reaction Details |
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 | Report a problem with these data |
| Target | Protein tyrosine phosphatase type IVA 3 |
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| Ligand | BDBM50059084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1931300 (CHEMBL4434551) |
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| IC50 | 130±n/a nM |
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| Citation |  Tasker, NR; Rastelli, EJ; Burnett, JC; Sharlow, ER; Lazo, JS; Wipf, P Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett29:2008-2015 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein tyrosine phosphatase type IVA 3 |
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| Name: | Protein tyrosine phosphatase type IVA 3 |
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| Synonyms: | PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 19546.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1461022 |
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| Residue: | 173 |
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| Sequence: | MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
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| BDBM50059084 |
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| n/a |
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| Name | BDBM50059084 |
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| Synonyms: | CHEMBL3393171 | US10308663, Thienopyridone (5) |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10N2OS |
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| Mol. Mass. | 242.296 |
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| SMILES | Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1 |
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| Structure | 
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