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Compile Data Set for Download or QSAR

Found 46 hits with Last Name = 'phuwapraisirisan' and Initial = 'p'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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2.24E+4n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestine sucrase using sucrose as substrate by Lineweaver-Burk plot analysis


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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2.38E+4n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestine maltase using maltose as substrate by Lineweaver-Burk plot analysis


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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4.75E+4n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestine sucrase using sucrose as substrate by Lineweaver-Burk plot analysis


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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6.45E+4n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestine maltase using maltose as substrate by Lineweaver-Burk plot analysis


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50208826
PNG
((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...)
Show SMILES COc1cc(ccc1O)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m1/s1
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2.88E+5n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-inhibitor complex at 0.1 to 1 mg/ml by...


Bioorg Med Chem Lett 22: 5215-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.068
BindingDB Entry DOI: 10.7270/Q28G8MR8
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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3.80E+5n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by Lineweaver-Burk plot ana...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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4.80E+5n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot ana...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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5.30E+5n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot ana...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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5.40E+5n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by Lineweaver-Burk plot ana...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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1.09E+6n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by Lineweaver-Burk plot analysi...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50208826
PNG
((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...)
Show SMILES COc1cc(ccc1O)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m1/s1
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1.34E+6n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-substrate-inhibitor complex at 0.1...


Bioorg Med Chem Lett 22: 5215-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.068
BindingDB Entry DOI: 10.7270/Q28G8MR8
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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1.64E+6n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot analysi...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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1.96E+6n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot analysi...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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3.07E+6n/an/an/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Competitive inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by Lineweaver-Burk plot analysi...


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal alpha-glucosidase maltase using maltose as substrate preincubated for 10 mins prior substrate addition measured after 40...


Bioorg Med Chem Lett 22: 1538-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.007
BindingDB Entry DOI: 10.7270/Q2MK6DC7
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 2.38E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal alpha-glucosidase sucrase using sucrose as substrate preincubated for 10 mins prior substrate addition measured after 40...


Bioorg Med Chem Lett 22: 1538-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.007
BindingDB Entry DOI: 10.7270/Q2MK6DC7
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50036139
PNG
(CHEMBL3358660)
Show SMILES [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)N[C@H]1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5+,6+,7-,8+,9-,10+,11-,12+/m0/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50036147
PNG
(CHEMBL3358661)
Show SMILES [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)N[C@H]1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5-,6+,7+,8-,9+,10-,11+,12-/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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n/an/a 5.31E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50035933
PNG
(CHEMBL3358659)
Show SMILES N[C@@H]1C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C6H13NO4/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,8-11H,1,7H2/t2-,3-,4+,5+,6+/m1/s1
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n/an/a 6.80E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50035932
PNG
(CHEMBL3358658)
Show SMILES N[C@H]1C[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C6H13NO4/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,8-11H,1,7H2/t2-,3+,4-,5-,6-/m0/s1
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n/an/a 7.30E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439694
PNG
(CHEMBL2418237)
Show SMILES COc1ccc(\C=C\C(=O)O[C@@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)cc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-4-2-8(6-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12-,14+,15+,16-/m1/s1
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n/an/a 2.08E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439695
PNG
(CHEMBL2418236)
Show SMILES COc1cc(\C=C\C(=O)O[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)ccc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-6-8(2-4-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12+,14+,15+,16-/m1/s1
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n/an/a 2.11E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50333465
PNG
((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |r,t:37|
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
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n/an/a 2.60E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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n/an/a 3.39E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50208826
PNG
((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...)
Show SMILES COc1cc(ccc1O)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(O)c(OC)c1 |r|
Show InChI InChI=1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m1/s1
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n/an/a 3.43E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate preincubated for 10 mins before substrate addition by glucose oxidase method


Bioorg Med Chem Lett 22: 5215-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.06.068
BindingDB Entry DOI: 10.7270/Q28G8MR8
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM4375
PNG
((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Show SMILES OC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
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n/an/a 3.47E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439692
PNG
(CHEMBL2418233)
Show SMILES O[C@@H]1C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11-,13+,14+,15-/m1/s1
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n/an/a 4.37E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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n/an/a 4.72E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123929
PNG
(CHEMBL3621760)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)c(C(CCc2ccccc2)c2ccc(O)cc2O)c1O)c1ccccc1 |r|
Show InChI InChI=1S/C36H40O7/c37-26-19-21-27(31(40)22-26)28(20-18-24-12-6-4-7-13-24)34-32(41)23-33(42)35(36(34)43)30(39)17-11-3-1-2-10-16-29(38)25-14-8-5-9-15-25/h4-9,12-15,19,21-23,28-29,37-38,40-43H,1-3,10-11,16-18,20H2/t28?,29-/m0/s1
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n/an/a 4.74E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439696
PNG
(CHEMBL2418235)
Show SMILES COc1cc(\C=C\C(=O)O[C@@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)ccc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-6-8(2-4-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12-,14+,15+,16-/m1/s1
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n/an/a 5.19E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439694
PNG
(CHEMBL2418237)
Show SMILES COc1ccc(\C=C\C(=O)O[C@@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)cc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-4-2-8(6-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12-,14+,15+,16-/m1/s1
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n/an/a 5.30E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439696
PNG
(CHEMBL2418235)
Show SMILES COc1cc(\C=C\C(=O)O[C@@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)ccc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-6-8(2-4-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12-,14+,15+,16-/m1/s1
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n/an/a 6.72E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM4375
PNG
((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Show SMILES OC(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
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n/an/a 8.75E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50123930
PNG
(CHEMBL3621759)
Show SMILES O[C@@H](CCCCCCCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 |r|
Show InChI InChI=1S/C21H26O5/c22-16-13-19(25)21(20(26)14-16)18(24)12-8-3-1-2-7-11-17(23)15-9-5-4-6-10-15/h4-6,9-10,13-14,17,22-23,25-26H,1-3,7-8,11-12H2/t17-/m0/s1
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n/an/a 9.49E+4n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Sucrase using sucrose as substrate assessed as glucose release after 40 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439695
PNG
(CHEMBL2418236)
Show SMILES COc1cc(\C=C\C(=O)O[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)ccc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-6-8(2-4-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12+,14+,15+,16-/m1/s1
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n/an/a 1.71E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439693
PNG
(CHEMBL2418238)
Show SMILES COc1ccc(\C=C\C(=O)O[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)cc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-4-2-8(6-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12+,14+,15+,16-/m1/s1
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n/an/a 3.67E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50439697
PNG
(CHEMBL2418234)
Show SMILES O[C@@H]1C[C@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11+,13+,14+,15-/m1/s1
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n/an/a 4.97E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Beta-galactosidase


(Homo sapiens (Human))
BDBM50365006
PNG
(CHEMBL1950779)
Show SMILES O[C@H]1C=C[C@@H](O)[C@H](O)[C@H]1O |r,c:2|
Show InChI InChI=1S/C6H10O4/c7-3-1-2-4(8)6(10)5(3)9/h1-10H/t3-,4+,5-,6-/m0/s1
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n/an/a 6.00E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of beta-galactosidase


Bioorg Med Chem Lett 22: 1538-40 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.007
BindingDB Entry DOI: 10.7270/Q2MK6DC7
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439693
PNG
(CHEMBL2418238)
Show SMILES COc1ccc(\C=C\C(=O)O[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)cc1O |r|
Show InChI InChI=1S/C16H20O8/c1-23-11-4-2-8(6-9(11)17)3-5-13(19)24-12-7-10(18)14(20)16(22)15(12)21/h2-6,10,12,14-18,20-22H,7H2,1H3/b5-3+/t10-,12+,14+,15+,16-/m1/s1
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n/an/a 8.05E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Sucrase-isomaltase, intestinal


(Rattus norvegicus (Rat))
BDBM50439697
PNG
(CHEMBL2418234)
Show SMILES O[C@@H]1C[C@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H18O8/c16-8-3-1-7(5-9(8)17)2-4-12(19)23-11-6-10(18)13(20)15(22)14(11)21/h1-5,10-11,13-18,20-22H,6H2/b4-2+/t10-,11+,13+,14+,15-/m1/s1
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n/an/a 9.54E+5n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...


Eur J Med Chem 66: 296-304 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.047
BindingDB Entry DOI: 10.7270/Q2X63PCD
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase


(Rattus norvegicus)
BDBM50123931
PNG
(CHEMBL3621761)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c2C(=O)C[C@H](Oc12)c1ccccc1 |r|
Show InChI InChI=1S/C21H22O9/c22-8-14-17(26)18(27)19(28)21(30-14)16-11(24)6-10(23)15-12(25)7-13(29-20(15)16)9-4-2-1-3-5-9/h1-6,13-14,17-19,21-24,26-28H,7-8H2/t13-,14+,17+,18-,19+,21-/m0/s1
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n/an/a 1.85E+6n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase method


Bioorg Med Chem Lett 25: 4529-33 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.069
BindingDB Entry DOI: 10.7270/Q2WD42C3
More data for this
Ligand-Target Pair