Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553771 (CHEMBL4776986) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.00300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50078007 (CHEMBL3417384) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b... | J Med Chem 58: 2431-40 (2015) Article DOI: 10.1021/jm501916k BindingDB Entry DOI: 10.7270/Q21V5GNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566289 (CHEMBL4878158) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553769 (CHEMBL4798887) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566283 (CHEMBL4876632) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566282 (CHEMBL4867453) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566310 (CHEMBL4855178) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566306 (CHEMBL4876492) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566303 (CHEMBL4867913) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553767 (CHEMBL4789659) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566304 (CHEMBL4858171) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50244625 (CHEMBL4076049) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti... | J Med Chem 61: 2266-2277 (2018) Article DOI: 10.1021/acs.jmedchem.7b01353 BindingDB Entry DOI: 10.7270/Q27M0BC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553779 (CHEMBL4742999) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566296 (CHEMBL4879304) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566301 (CHEMBL4876350) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172383 (CHEMBL3809968) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172387 (CHEMBL3808761) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50070386 (CHEMBL3408737) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-DAMGO from recombinant human mu opioid receptor expressed in CHO cell membrane incubated for 60 mins by liquid scintillation cou... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50346330 ((R)-N-((S)-2-(2-amino-2-oxoethyl)-3-oxo-2,3,4,5-te...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Brussel Curated by ChEMBL | Assay Description Binding affinity to Mu-type opioid receptor (unknown origin) | ACS Med Chem Lett 8: 1177-1182 (2017) Article DOI: 10.1021/acsmedchemlett.7b00347 BindingDB Entry DOI: 10.7270/Q2251MRN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50244579 (CHEMBL4094033) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti... | J Med Chem 61: 2266-2277 (2018) Article DOI: 10.1021/acs.jmedchem.7b01353 BindingDB Entry DOI: 10.7270/Q27M0BC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566308 (CHEMBL4857085) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553770 (CHEMBL4758754) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566302 (CHEMBL4878369) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172370 (CHEMBL3809767) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566290 (CHEMBL4857851) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50565846 (CHEMBL4796315) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75, Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr by gamma ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01547 BindingDB Entry DOI: 10.7270/Q2V40ZZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50583259 (CHEMBL5094438) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-[Nle75,Tyr77][Pyr1]-Ape13 from YFP-tagged human APJ expressed in HEK293 cell membranes assessed as inhibition constant incubat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01708 BindingDB Entry DOI: 10.7270/Q20R9T9K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50077994 (CHEMBL3417378) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b... | J Med Chem 58: 2431-40 (2015) Article DOI: 10.1021/jm501916k BindingDB Entry DOI: 10.7270/Q21V5GNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172369 (CHEMBL3810388) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553768 (CHEMBL4744531) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50244587 (CHEMBL4076652) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti... | J Med Chem 61: 2266-2277 (2018) Article DOI: 10.1021/acs.jmedchem.7b01353 BindingDB Entry DOI: 10.7270/Q27M0BC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553772 (CHEMBL4749016) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553775 (CHEMBL4745899) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50078002 (CHEMBL3417389) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b... | J Med Chem 58: 2431-40 (2015) Article DOI: 10.1021/jm501916k BindingDB Entry DOI: 10.7270/Q21V5GNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172368 (CHEMBL3809335) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566280 (CHEMBL4859698) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172388 (CHEMBL3809291) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172371 (CHEMBL3809818) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566305 (CHEMBL4849012) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50078006 (CHEMBL3417385) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b... | J Med Chem 58: 2431-40 (2015) Article DOI: 10.1021/jm501916k BindingDB Entry DOI: 10.7270/Q21V5GNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566307 (CHEMBL4862772) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566291 (CHEMBL4863977) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50553767 (CHEMBL4789659) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS1 stably expressed in CHO-K1 cell membranes incubated for 60 mins by gamma counter metho... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553777 (CHEMBL4597094) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50566294 (CHEMBL4869716) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I] [NIe75,Tyr77]Pyr-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cells incubated for 1 hr by gamma counting a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01941 BindingDB Entry DOI: 10.7270/Q24F1VHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50077995 (CHEMBL3417377) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b... | J Med Chem 58: 2431-40 (2015) Article DOI: 10.1021/jm501916k BindingDB Entry DOI: 10.7270/Q21V5GNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50553776 (CHEMBL4747286) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50172390 (CHEMBL3809537) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Sherbrooke Curated by ChEMBL | Assay Description Displacement of [125I]-Apelin-13[Glp65, Nle75, Tyr77] from YFP epitope-tagged human APJ expressed in HEK-293 cells after 1 hr by gamma counting metho... | J Med Chem 59: 2962-72 (2016) Article DOI: 10.1021/acs.jmedchem.5b01549 BindingDB Entry DOI: 10.7270/Q23N258H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurotensin receptor type 2 (Homo sapiens (Human)) | BDBM50048908 (CHEMBL415788) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-neurotensin from human recombinant NTS2 stably expressed in human 1321N1 cell membranes incubated for 60 mins by gamma counter... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01376 BindingDB Entry DOI: 10.7270/Q2H41W2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apelin receptor (Homo sapiens (Human)) | BDBM50583256 (CHEMBL5087847) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]-[Nle75,Tyr77][Pyr1]-Ape13 from YFP-tagged human APJ expressed in HEK293 cell membranes assessed as inhibition constant incubat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01708 BindingDB Entry DOI: 10.7270/Q20R9T9K | |||||||||||
More data for this Ligand-Target Pair |
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