Found 46 hits with Last Name = 'hosmane' and Initial = 'rs' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine deaminase
(Homo sapiens (Human)) | BDBM50367032
(COFORMYCIN)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |r,c:18| Show InChI InChI=1S/C11H16N4O5/c16-2-6-8(18)9(19)11(20-6)15-4-14-7-5(17)1-12-3-13-10(7)15/h3-6,8-9,11,16-19H,1-2H2,(H,12,13)/t5-,6-,8-,9-,11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.000100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of adenosine deaminase |
Bioorg Med Chem Lett 22: 7214-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.053
BindingDB Entry DOI: 10.7270/Q2MC916H |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Homo sapiens (Human)) | BDBM22925
((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |c:17| Show InChI InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 0.000100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of adenosine deaminase |
Bioorg Med Chem Lett 22: 7214-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.053
BindingDB Entry DOI: 10.7270/Q2MC916H |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM22925
((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |c:17| Show InChI InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
Article
PubMed
| 0.00100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50367032
(COFORMYCIN)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |r,c:18| Show InChI InChI=1S/C11H16N4O5/c16-2-6-8(18)9(19)11(20-6)15-4-14-7-5(17)1-12-3-13-10(7)15/h3-6,8-9,11,16-19H,1-2H2,(H,12,13)/t5-,6-,8-,9-,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM22925
((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |c:17| Show InChI InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PubMed
| 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity against Adenosine deaminase from calf intestinal mucosa was determined |
Bioorg Med Chem Lett 11: 2893-6 (2001)
BindingDB Entry DOI: 10.7270/Q28K79MD |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50034908
((2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2...)Show SMILES CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C14H23N5O/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17)/t10-,11+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity against Adenosine deaminase from calf intestinal mucosa was determined |
Bioorg Med Chem Lett 11: 2893-6 (2001)
BindingDB Entry DOI: 10.7270/Q28K79MD |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM21955
(4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)Show SMILES Nc1n[nH]c(=O)c2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C10H13N5O5/c11-8-4-5(9(19)14-13-8)15(2-12-4)10-7(18)6(17)3(1-16)20-10/h2-3,6-7,10,16-18H,1H2,(H2,11,13)(H,14,19)/t3-,6-,7-,10-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.06E+4 | -28.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Maryland Baltimore County
| Assay Description
The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri... |
J Med Chem 51: 694-8 (2008)
Article DOI: 10.1021/jm700931t
BindingDB Entry DOI: 10.7270/Q20R9MP1 |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139883
(1-(4-Methoxy-benzyl)-6,7-dimethyl-8-propoxy-1,6,7,...)Show SMILES CCCOC1N(C)N(C)C=Nc2ncn(Cc3ccc(OC)cc3)c12 |c:9| Show InChI InChI=1S/C18H25N5O2/c1-5-10-25-18-16-17(19-12-21(2)22(18)3)20-13-23(16)11-14-6-8-15(24-4)9-7-14/h6-9,12-13,18H,5,10-11H2,1-4H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM21953
(4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)Show SMILES Nc1n[nH]c(=O)c2n(cnc12)[C@H]1C[C@H](O)[C@@H](CO)O1 |r| Show InChI InChI=1S/C10H13N5O4/c11-9-7-8(10(18)14-13-9)15(3-12-7)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H2,11,13)(H,14,18)/t4-,5+,6+/m0/s1 | PDB
MMDB
KEGG
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DrugBank
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.21E+4 | -28.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Maryland Baltimore County
| Assay Description
The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri... |
J Med Chem 51: 694-8 (2008)
Article DOI: 10.1021/jm700931t
BindingDB Entry DOI: 10.7270/Q20R9MP1 |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139887
(8-Butoxy-1-(4-methoxy-benzyl)-6,7-dimethyl-1,6,7,8...)Show SMILES CCCCOC1N(C)N(C)C=Nc2ncn(Cc3ccc(OC)cc3)c12 |c:10| Show InChI InChI=1S/C19H27N5O2/c1-5-6-11-26-19-17-18(20-13-22(2)23(19)3)21-14-24(17)12-15-7-9-16(25-4)10-8-15/h7-10,13-14,19H,5-6,11-12H2,1-4H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50378883
(CHEMBL1645489)Show SMILES OCC1(NC(=O)OCc2ccccc2)NC(=O)c2ncn(Cc3ccccc3)c2NC1=O Show InChI InChI=1S/C22H21N5O5/c28-13-22(26-21(31)32-12-16-9-5-2-6-10-16)20(30)24-18-17(19(29)25-22)23-14-27(18)11-15-7-3-1-4-8-15/h1-10,14,28H,11-13H2,(H,24,30)(H,25,29)(H,26,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Competitive inhibition of guanase by Lineweaver-Burk plot analysis |
Bioorg Med Chem Lett 21: 756-9 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.109
BindingDB Entry DOI: 10.7270/Q2XK8GJV |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139885
(8-Ethoxy-1-(4-methoxy-benzyl)-6,7-dimethyl-1,6,7,8...)Show SMILES CCOC1N(C)N(C)C=Nc2ncn(Cc3ccc(OC)cc3)c12 |c:8| Show InChI InChI=1S/C17H23N5O2/c1-5-24-17-15-16(18-11-20(2)21(17)3)19-12-22(15)10-13-6-8-14(23-4)9-7-13/h6-9,11-12,17H,5,10H2,1-4H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50193757
(3-benzyl-4,5,7,8-tetrahydro-6-hydroxymethyl-6H-imi...)Show InChI InChI=1S/C14H14N4O3/c19-7-10-13(20)17-12-11(14(21)16-10)15-8-18(12)6-9-4-2-1-3-5-9/h1-5,8,10,19H,6-7H2,(H,16,21)(H,17,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of rabbit liver guanase |
Bioorg Med Chem Lett 16: 5551-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.033
BindingDB Entry DOI: 10.7270/Q2FB52J0 |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139886
(1-(4-Methoxy-benzyl)-8-(2-methoxy-ethoxy)-6,7-dime...)Show SMILES COCCOC1N(C)N(C)C=Nc2ncn(Cc3ccc(OC)cc3)c12 |c:10| Show InChI InChI=1S/C18H25N5O3/c1-21-12-19-17-16(18(22(21)2)26-10-9-24-3)23(13-20-17)11-14-5-7-15(25-4)8-6-14/h5-8,12-13,18H,9-11H2,1-4H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139881
(8-Methoxy-1-(4-methoxy-benzyl)-6,7-dimethyl-1,6,7,...)Show SMILES COC1N(C)N(C)C=Nc2ncn(Cc3ccc(OC)cc3)c12 |c:7| Show InChI InChI=1S/C16H21N5O2/c1-19-10-17-15-14(16(23-4)20(19)2)21(11-18-15)9-12-5-7-13(22-3)8-6-12/h5-8,10-11,16H,9H2,1-4H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM21957
(4-(hydrazinocarbonyl)-1-beta-D-ribofuranosyl-1H-im...)Show SMILES NNC(=N)c1c(ncn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)NN |r| Show InChI InChI=1S/C10H17N7O5/c11-8(15-12)5-4(9(21)16-13)14-2-17(5)10-7(20)6(19)3(1-18)22-10/h2-3,6-7,10,18-20H,1,12-13H2,(H2,11,15)(H,16,21)/t3-,6-,7-,10-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.65E+4 | -26.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Maryland Baltimore County
| Assay Description
The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri... |
J Med Chem 51: 694-8 (2008)
Article DOI: 10.1021/jm700931t
BindingDB Entry DOI: 10.7270/Q20R9MP1 |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50106015
(2-(4,6-Diamino-8-imino-8,8a-dihydro-3aH-1,3,5,7-te...)Show InChI InChI=1S/C9H15N7O2/c10-7-5-6(8(11)15-9(12)14-7)16(3-13-5)4-18-2-1-17/h13,17H,1-4H2,(H5,10,11,12,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 2.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity against Guanine deaminase (guanase) from rabbit liver was determined |
Bioorg Med Chem Lett 11: 2893-6 (2001)
BindingDB Entry DOI: 10.7270/Q28K79MD |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139884
(8-Isopropoxy-1-(4-methoxy-benzyl)-6,7-dimethyl-1,6...)Show SMILES COc1ccc(Cn2cnc3N=CN(C)N(C)C(OC(C)C)c23)cc1 |c:11| Show InChI InChI=1S/C18H25N5O2/c1-13(2)25-18-16-17(19-11-21(3)22(18)4)20-12-23(16)10-14-6-8-15(24-5)9-7-14/h6-9,11-13,18H,10H2,1-5H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM21956
(7-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)Show SMILES Nc1n[nH]c(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c12 |r| Show InChI InChI=1S/C10H13N5O5/c11-8-5-4(9(19)14-13-8)12-2-15(5)10-7(18)6(17)3(1-16)20-10/h2-3,6-7,10,16-18H,1H2,(H2,11,13)(H,14,19)/t3-,6-,7-,10-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.14E+4 | -24.5 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Maryland Baltimore County
| Assay Description
The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri... |
J Med Chem 51: 694-8 (2008)
Article DOI: 10.1021/jm700931t
BindingDB Entry DOI: 10.7270/Q20R9MP1 |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM21954
(7-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)Show SMILES Nc1n[nH]c(=O)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c12 |r| Show InChI InChI=1S/C10H13N5O4/c11-9-8-7(10(18)14-13-9)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H2,11,13)(H,14,18)/t4-,5+,6+/m0/s1 | PDB
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| 5.20E+4 | -24.5 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
University of Maryland Baltimore County
| Assay Description
The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri... |
J Med Chem 51: 694-8 (2008)
Article DOI: 10.1021/jm700931t
BindingDB Entry DOI: 10.7270/Q20R9MP1 |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50193756
(4,5,7,8-tetrahydro-6-hydroxymethyl-6H-imidazo[4,5-...)Show InChI InChI=1S/C7H8N4O3/c12-1-3-6(13)11-5-4(7(14)10-3)8-2-9-5/h2-3,12H,1H2,(H,8,9)(H,10,14)(H,11,13) | PDB
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| 5.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of rabbit liver guanase |
Bioorg Med Chem Lett 16: 5551-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.033
BindingDB Entry DOI: 10.7270/Q2FB52J0 |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139880
(1-(4-Methoxy-benzyl)-8-(4-methoxy-benzyloxy)-6,7-d...)Show SMILES COc1ccc(COC2N(C)N(C)C=Nc3ncn(Cc4ccc(OC)cc4)c23)cc1 |c:13| Show InChI InChI=1S/C23H27N5O3/c1-26-15-24-22-21(28(16-25-22)13-17-5-9-19(29-3)10-6-17)23(27(26)2)31-14-18-7-11-20(30-4)12-8-18/h5-12,15-16,23H,13-14H2,1-4H3 | PDB
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| 7.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50139889
(1-(4-Methoxy-benzyl)-6,7-dimethyl-8-(3-methyl-benz...)Show SMILES COc1ccc(Cn2cnc3N=CN(C)N(C)C(OCc4cccc(C)c4)c23)cc1 |c:11| Show InChI InChI=1S/C23H27N5O2/c1-17-6-5-7-19(12-17)14-30-23-21-22(24-15-26(2)27(23)3)25-16-28(21)13-18-8-10-20(29-4)11-9-18/h5-12,15-16,23H,13-14H2,1-4H3 | PDB
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| 9.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity towards calf spleen adenosine deaminase was determined |
J Med Chem 47: 1044-50 (2004)
Article DOI: 10.1021/jm0304257
BindingDB Entry DOI: 10.7270/Q2GM882D |
More data for this
Ligand-Target Pair | |
Adenosine deaminase
(Bos taurus (bovine)) | BDBM50106015
(2-(4,6-Diamino-8-imino-8,8a-dihydro-3aH-1,3,5,7-te...)Show InChI InChI=1S/C9H15N7O2/c10-7-5-6(8(11)15-9(12)14-7)16(3-13-5)4-18-2-1-17/h13,17H,1-4H2,(H5,10,11,12,14,15) | PDB
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| 1.52E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Binding affinity against Adenosine deaminase from calf intestinal mucosa was determined |
Bioorg Med Chem Lett 11: 2893-6 (2001)
BindingDB Entry DOI: 10.7270/Q28K79MD |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50073384
(3-Benzyl-3H-imidazo[4,5-e][1,4]diazepine-6,8-dione...)Show InChI InChI=1S/C13H10N4O2/c18-10-6-14-12-11(13(19)16-10)15-8-17(12)7-9-4-2-1-3-5-9/h1-6,8H,7H2,(H,16,18,19) | PDB
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| 2.27E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory effect on rabbit liver guanase |
Bioorg Med Chem Lett 8: 3649-52 (1999)
BindingDB Entry DOI: 10.7270/Q2BV7FR7 |
More data for this
Ligand-Target Pair | |
Guanine deaminase
(Homo sapiens (Human)) | BDBM50401837
(CHEMBL2203870)Show InChI InChI=1S/C6H8N4O2/c11-3-1-7-5-4(6(12)10-3)8-2-9-5/h2-3,7,11H,1H2,(H,8,9)(H,10,12) | PDB
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| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of guanase |
Bioorg Med Chem Lett 22: 7214-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.053
BindingDB Entry DOI: 10.7270/Q2MC916H |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474366
(CHEMBL2112136)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1 Show InChI InChI=1S/C23H37N5O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-21(31)19-20(22(32)27-23)28(15-25-19)18-13-16(30)17(14-29)33-18/h15-18,29-30H,2-14H2,1H3,(H2,24,26,27,31,32)/t16-,17+,18+/m0/s1 | PDB
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| n/a | n/a | 6.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474374
(CHEMBL501187)Show SMILES CCCCCCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C29H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-30-29-32-26(38)22-23(27(39)33-29)34(20-31-22)28-25(37)24(36)21(19-35)40-28/h20-21,24-25,28,35-37H,2-19H2,1H3,(H2,30,32,33,38,39)/t21-,24-,25-,28-/m1/s1 | PDB
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| n/a | n/a | 5.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474372
(CHEMBL3114565)Show SMILES CCCCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C27H45N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-28-27-30-24(36)20-21(25(37)31-27)32(18-29-20)26-23(35)22(34)19(17-33)38-26/h18-19,22-23,26,33-35H,2-17H2,1H3,(H2,28,30,31,36,37)/t19-,22-,23-,26-/m1/s1 | PDB
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| n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474368
(CHEMBL3114564)Show SMILES CCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C25H41N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-26-25-28-22(34)18-19(23(35)29-25)30(16-27-18)24-21(33)20(32)17(15-31)36-24/h16-17,20-21,24,31-33H,2-15H2,1H3,(H2,26,28,29,34,35)/t17-,20-,21-,24-/m1/s1 | PDB
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| n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474370
(CHEMBL3114563)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C23H37N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-20(32)16-17(21(33)27-23)28(14-25-16)22-19(31)18(30)15(13-29)34-22/h14-15,18-19,22,29-31H,2-13H2,1H3,(H2,24,26,27,32,33)/t15-,18-,19-,22-/m1/s1 | PDB
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| n/a | n/a | 3.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474371
(CHEMBL2111998)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(cnc2c(=O)[nH]1)[C@@H]1C[C@H](O)[C@@H](CO)O1 Show InChI InChI=1S/C23H37N5O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-21(31)19-20(22(32)27-23)28(15-25-19)18-13-16(30)17(14-29)33-18/h15-18,29-30H,2-14H2,1H3,(H2,24,26,27,31,32)/t16-,17+,18-/m0/s1 | PDB
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| n/a | n/a | 3.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474371
(CHEMBL2111998)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(cnc2c(=O)[nH]1)[C@@H]1C[C@H](O)[C@@H](CO)O1 Show InChI InChI=1S/C23H37N5O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-21(31)19-20(22(32)27-23)28(15-25-19)18-13-16(30)17(14-29)33-18/h15-18,29-30H,2-14H2,1H3,(H2,24,26,27,31,32)/t16-,17+,18-/m0/s1 | PDB
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| n/a | n/a | 5.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474368
(CHEMBL3114564)Show SMILES CCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C25H41N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-26-25-28-22(34)18-19(23(35)29-25)30(16-27-18)24-21(33)20(32)17(15-31)36-24/h16-17,20-21,24,31-33H,2-15H2,1H3,(H2,26,28,29,34,35)/t17-,20-,21-,24-/m1/s1 | PDB
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| Article
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| n/a | n/a | 5.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474374
(CHEMBL501187)Show SMILES CCCCCCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C29H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-30-29-32-26(38)22-23(27(39)33-29)34(20-31-22)28-25(37)24(36)21(19-35)40-28/h20-21,24-25,28,35-37H,2-19H2,1H3,(H2,30,32,33,38,39)/t21-,24-,25-,28-/m1/s1 | PDB
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| n/a | n/a | >8.86E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474372
(CHEMBL3114565)Show SMILES CCCCCCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C27H45N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-28-27-30-24(36)20-21(25(37)31-27)32(18-29-20)26-23(35)22(34)19(17-33)38-26/h18-19,22-23,26,33-35H,2-17H2,1H3,(H2,28,30,31,36,37)/t19-,22-,23-,26-/m1/s1 | PDB
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| n/a | n/a | >9.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474370
(CHEMBL3114563)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C23H37N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-20(32)16-17(21(33)27-23)28(14-25-16)22-19(31)18(30)15(13-29)34-22/h14-15,18-19,22,29-31H,2-13H2,1H3,(H2,24,26,27,32,33)/t15-,18-,19-,22-/m1/s1 | PDB
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| n/a | n/a | >1.04E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474365
(CHEMBL145949)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(Cc3ccc(OC)cc3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C26H37N5O3/c1-3-4-5-6-7-8-9-10-11-12-17-27-26-29-24(32)22-23(25(33)30-26)31(19-28-22)18-20-13-15-21(34-2)16-14-20/h13-16,19H,3-12,17-18H2,1-2H3,(H2,27,29,30,32,33) | PDB
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| n/a | n/a | >1.06E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474365
(CHEMBL145949)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(Cc3ccc(OC)cc3)cnc2c(=O)[nH]1 Show InChI InChI=1S/C26H37N5O3/c1-3-4-5-6-7-8-9-10-11-12-17-27-26-29-24(32)22-23(25(33)30-26)31(19-28-22)18-20-13-15-21(34-2)16-14-20/h13-16,19H,3-12,17-18H2,1-2H3,(H2,27,29,30,32,33) | PDB
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.06E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474366
(CHEMBL2112136)Show SMILES CCCCCCCCCCCCNc1nc(=O)c2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1 Show InChI InChI=1S/C23H37N5O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-23-26-21(31)19-20(22(32)27-23)28(15-25-19)18-13-16(30)17(14-29)33-18/h15-18,29-30H,2-14H2,1H3,(H2,24,26,27,31,32)/t16-,17+,18+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.07E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474369
(CHEMBL3114562)Show SMILES CCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C21H33N5O6/c1-2-3-4-5-6-7-8-9-10-22-21-24-18(30)14-15(19(31)25-21)26(12-23-14)20-17(29)16(28)13(11-27)32-20/h12-13,16-17,20,27-29H,2-11H2,1H3,(H2,22,24,25,30,31)/t13-,16-,17-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474369
(CHEMBL3114562)Show SMILES CCCCCCCCCCNc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2c(=O)[nH]1 |r| Show InChI InChI=1S/C21H33N5O6/c1-2-3-4-5-6-7-8-9-10-22-21-24-18(30)14-15(19(31)25-21)26(12-23-14)20-17(29)16(28)13(11-27)32-20/h12-13,16-17,20,27-29H,2-11H2,1H3,(H2,22,24,25,30,31)/t13-,16-,17-,20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474373
(CHEMBL611608)Show SMILES OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c1c(=O)[nH]c(Nc1ccccc1)nc2=O |r| Show InChI InChI=1S/C17H17N5O6/c23-6-9-12(24)13(25)16(28-9)22-7-18-10-11(22)15(27)21-17(20-14(10)26)19-8-4-2-1-3-5-8/h1-5,7,9,12-13,16,23-25H,6H2,(H2,19,20,21,26,27)/t9-,12-,13-,16?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.29E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474373
(CHEMBL611608)Show SMILES OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c1c(=O)[nH]c(Nc1ccccc1)nc2=O |r| Show InChI InChI=1S/C17H17N5O6/c23-6-9-12(24)13(25)16(28-9)22-7-18-10-11(22)15(27)21-17(20-14(10)26)19-8-4-2-1-3-5-8/h1-5,7,9,12-13,16,23-25H,6H2,(H2,19,20,21,26,27)/t9-,12-,13-,16?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.29E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474367
(CHEMBL344336)Show InChI InChI=1S/C18H29N5O2/c1-2-3-4-5-6-7-8-9-10-11-12-19-18-22-16(24)14-15(17(25)23-18)21-13-20-14/h13H,2-12H2,1H3,(H3,19,22,23,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.43E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Suv3 helicase using RNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
ATP-dependent RNA helicase SUPV3L1, mitochondrial
(Homo sapiens) | BDBM50474367
(CHEMBL344336)Show InChI InChI=1S/C18H29N5O2/c1-2-3-4-5-6-7-8-9-10-11-12-19-18-22-16(24)14-15(17(25)23-18)21-13-20-14/h13H,2-12H2,1H3,(H3,19,22,23,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.43E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibitory activity determined against human Suv3 helicase using DNA as substrate |
J Med Chem 46: 4776-89 (2003)
Article DOI: 10.1021/jm030277k
BindingDB Entry DOI: 10.7270/Q23B62WR |
More data for this
Ligand-Target Pair | |
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