Compile Data Set for Download or QSAR

Found 150 hits with Last Name = 'burdzovic-wizemann' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192487 ((7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-...) Show SMILES COc1cc2CNc3c(N[C@H](C)c4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C21H23N5O2/c1-13(14-7-5-4-6-8-14)25-20-19-21(24-12-23-20)26-16-10-18(28-3)17(27-2)9-15(16)11-22-19/h4-10,12-13,22H,11H2,1-3H3,(H2,23,24,25,26)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192474 (CHEMBL215191 | benzyl-(7,8-dimethoxy-10,11-dihydro...) Show SMILES COc1cc2CNc3c(NCc4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H21N5O2/c1-26-16-8-14-11-21-18-19(22-10-13-6-4-3-5-7-13)23-12-24-20(18)25-15(14)9-17(16)27-2/h3-9,12,21H,10-11H2,1-2H3,(H2,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192498 ((3-chloro-4-fluoro-benzyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(NCc4ccc(F)c(Cl)c4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H19ClFN5O2/c1-28-16-6-12-9-23-18-19(24-8-11-3-4-14(22)13(21)5-11)25-10-26-20(18)27-15(12)7-17(16)29-2/h3-7,10,23H,8-9H2,1-2H3,(H2,24,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180448 ((3-Bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-ox...) Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H17BrN4O3/c1-25-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)26-2/h3-8,10,21H,9H2,1-2H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192477 ((3-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4cccc(Cl)c4F)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-14-6-10-8-22-17-18(25-12-5-3-4-11(20)16(12)21)23-9-24-19(17)28-13(10)7-15(14)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180448 ((3-Bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-ox...) Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H17BrN4O3/c1-25-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)26-2/h3-8,10,21H,9H2,1-2H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180448 ((3-Bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-ox...) Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H17BrN4O3/c1-25-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)26-2/h3-8,10,21H,9H2,1-2H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180448 ((3-Bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-ox...) Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H17BrN4O3/c1-25-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)26-2/h3-8,10,21H,9H2,1-2H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192487 ((7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-...) Show SMILES COc1cc2CNc3c(N[C@H](C)c4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C21H23N5O2/c1-13(14-7-5-4-6-8-14)25-20-19-21(24-12-23-20)26-16-10-18(28-3)17(27-2)9-15(16)11-22-19/h4-10,12-13,22H,11H2,1-3H3,(H2,23,24,25,26)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192471 ((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...) Show SMILES COc1cc2CNc3c(Nc4ccc5ccccc5c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C23H20N4O3/c1-28-19-10-16-12-24-21-22(25-13-26-23(21)30-18(16)11-20(19)29-2)27-17-8-7-14-5-3-4-6-15(14)9-17/h3-11,13,24H,12H2,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180453 ((3-Chloro-4-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-15-5-10-8-22-17-18(25-11-3-4-13(21)12(20)6-11)23-9-24-19(17)28-14(10)7-16(15)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180453 ((3-Chloro-4-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-15-5-10-8-22-17-18(25-11-3-4-13(21)12(20)6-11)23-9-24-19(17)28-14(10)7-16(15)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192478 (1-(3-bromo-phenoxy)-7,8-dimethoxy-10,11-dihydro-5-...) Show SMILES COc1cc2CNc3c(Oc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16BrN3O4/c1-24-15-6-11-9-21-17-18(26-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)25-2/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192497 ((7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-...) Show SMILES COc1cccc(CNc2ncnc3Nc4cc(OC)c(OC)cc4CNc23)c1 Show InChI InChI=1S/C21H23N5O3/c1-27-15-6-4-5-13(7-15)10-23-20-19-21(25-12-24-20)26-16-9-18(29-3)17(28-2)8-14(16)11-22-19/h4-9,12,22H,10-11H2,1-3H3,(H2,23,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180443 ((3-Chloro-4-fluoro-phenyl)-(8-methoxy-10,11-dihydr...) Show SMILES COc1ccc2Oc3ncnc(Nc4ccc(F)c(Cl)c4)c3NCc2c1 Show InChI InChI=1S/C18H14ClFN4O2/c1-25-12-3-5-15-10(6-12)8-21-16-17(22-9-23-18(16)26-15)24-11-2-4-14(20)13(19)7-11/h2-7,9,21H,8H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192474 (CHEMBL215191 | benzyl-(7,8-dimethoxy-10,11-dihydro...) Show SMILES COc1cc2CNc3c(NCc4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H21N5O2/c1-26-16-8-14-11-21-18-19(22-10-13-6-4-3-5-7-13)23-12-24-20(18)25-15(14)9-17(16)27-2/h3-9,12,21H,10-11H2,1-2H3,(H2,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192501 ((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...) Show SMILES COc1cc2CNc3c(Nc4cccc(c4)C#C)ncnc3Oc2cc1OC Show InChI InChI=1S/C21H18N4O3/c1-4-13-6-5-7-15(8-13)25-20-19-21(24-12-23-20)28-16-10-18(27-3)17(26-2)9-14(16)11-22-19/h1,5-10,12,22H,11H2,2-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192496 (1-(3-chloro-phenylsulfanyl)-7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Oc2cc1OC)ncnc3Sc1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3S/c1-24-15-6-11-9-21-17-18(26-14(11)8-16(15)25-2)22-10-23-19(17)27-13-5-3-4-12(20)7-13/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180440 (1-(3-Bromo-phenylamino)-10,11-dihydro-5-oxa-2,4,11...) Show SMILES OC(=O)c1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C18H13BrN4O3/c19-12-2-1-3-13(7-12)23-16-15-17(22-9-21-16)26-14-5-4-10(18(24)25)6-11(14)8-20-15/h1-7,9,20H,8H2,(H,24,25)(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180424 ((3-Chloro-4-fluoro-phenyl)-(8-fluoro-10,11-dihydro...) Show SMILES Fc1ccc2Oc3ncnc(Nc4ccc(F)c(Cl)c4)c3NCc2c1 Show InChI InChI=1S/C17H11ClF2N4O/c18-12-6-11(2-3-13(12)20)24-16-15-17(23-8-22-16)25-14-4-1-10(19)5-9(14)7-21-15/h1-6,8,21H,7H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180438 ((8-Bromo-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo...) Show SMILES Brc1cccc(Nc2ncnc3Oc4ccc(Br)cc4CNc23)c1 Show InChI InChI=1S/C17H12Br2N4O/c18-11-2-1-3-13(7-11)23-16-15-17(22-9-21-16)24-14-5-4-12(19)6-10(14)8-20-15/h1-7,9,20H,8H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180432 ((8-Chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibenz...) Show SMILES Fc1ccc(Nc2ncnc3Oc4ccc(Cl)cc4CNc23)cc1Cl Show InChI InChI=1S/C17H11Cl2FN4O/c18-10-1-4-14-9(5-10)7-21-15-16(22-8-23-17(15)25-14)24-11-2-3-13(20)12(19)6-11/h1-6,8,21H,7H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180433 ((3-Bromo-phenyl)-(8-methoxy-10,11-dihydro-5-oxa-2,...) Show SMILES COc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C18H15BrN4O2/c1-24-14-5-6-15-11(7-14)9-20-16-17(21-10-22-18(16)25-15)23-13-4-2-3-12(19)8-13/h2-8,10,20H,9H2,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180447 ((3-Chloro-4-fluoro-phenyl)-(7-methoxy-10,11-dihydr...) Show SMILES COc1ccc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2c1 Show InChI InChI=1S/C18H14ClFN4O2/c1-25-12-4-2-10-8-21-16-17(22-9-23-18(16)26-15(10)7-12)24-11-3-5-14(20)13(19)6-11/h2-7,9,21H,8H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192479 ((5-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4cc(Cl)ccc4F)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-15-5-10-8-22-17-18(25-13-6-11(20)3-4-12(13)21)23-9-24-19(17)28-14(10)7-16(15)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180441 ((3-Chloro-4-fluoro-phenyl)-(10,11-dihydro-5-oxa-2,...) Show SMILES Fc1ccc(Nc2ncnc3Oc4ccccc4CNc23)cc1Cl Show InChI InChI=1S/C17H12ClFN4O/c18-12-7-11(5-6-13(12)19)23-16-15-17(22-9-21-16)24-14-4-2-1-3-10(14)8-20-15/h1-7,9,20H,8H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192480 ((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...) Show SMILES COc1cc2CNc3c(Nc4ccc5c[nH]nc5c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C20H18N6O3/c1-27-16-5-12-8-21-18-19(25-13-4-3-11-9-24-26-14(11)6-13)22-10-23-20(18)29-15(12)7-17(16)28-2/h3-7,9-10,21H,8H2,1-2H3,(H,24,26)(H,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192473 (7-(3-bromophenoxy)-13,14-dimethoxy-9-methyl-2-oxa-...) Show SMILES COc1cc2CN(C)c3c(Oc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C20H18BrN3O4/c1-24-10-12-7-16(25-2)17(26-3)9-15(12)28-20-18(24)19(22-11-23-20)27-14-6-4-5-13(21)8-14/h4-9,11H,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180453 ((3-Chloro-4-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-15-5-10-8-22-17-18(25-11-3-4-13(21)12(20)6-11)23-9-24-19(17)28-14(10)7-16(15)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192489 (1-(3-bromo-phenylsulfanyl)-7,8-dimethoxy-10,11-dih...) Show SMILES COc1cc2CNc3c(Oc2cc1OC)ncnc3Sc1cccc(Br)c1 Show InChI InChI=1S/C19H16BrN3O3S/c1-24-15-6-11-9-21-17-18(26-14(11)8-16(15)25-2)22-10-23-19(17)27-13-5-3-4-12(20)7-13/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180453 ((3-Chloro-4-fluoro-phenyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Nc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16ClFN4O3/c1-26-15-5-10-8-22-17-18(25-11-3-4-13(21)12(20)6-11)23-9-24-19(17)28-14(10)7-16(15)27-2/h3-7,9,22H,8H2,1-2H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192489 (1-(3-bromo-phenylsulfanyl)-7,8-dimethoxy-10,11-dih...) Show SMILES COc1cc2CNc3c(Oc2cc1OC)ncnc3Sc1cccc(Br)c1 Show InChI InChI=1S/C19H16BrN3O3S/c1-24-15-6-11-9-21-17-18(26-14(11)8-16(15)25-2)22-10-23-19(17)27-13-5-3-4-12(20)7-13/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192500 ((3-bromo-phenyl)-(7,8-dimethoxy-10,11-dihydro-5H-2...) Show SMILES COc1cc2CNc3c(Nc4cccc(Br)c4)ncnc3Nc2cc1OC Show InChI InChI=1S/C19H18BrN5O2/c1-26-15-6-11-9-21-17-18(24-13-5-3-4-12(20)7-13)22-10-23-19(17)25-14(11)8-16(15)27-2/h3-8,10,21H,9H2,1-2H3,(H2,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180426 ((3-Bromo-phenyl)-(8-fluoro-10,11-dihydro-5-oxa-2,4...) Show SMILES Fc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C17H12BrFN4O/c18-11-2-1-3-13(7-11)23-16-15-17(22-9-21-16)24-14-5-4-12(19)6-10(14)8-20-15/h1-7,9,20H,8H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192498 ((3-chloro-4-fluoro-benzyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(NCc4ccc(F)c(Cl)c4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H19ClFN5O2/c1-28-16-6-12-9-23-18-19(24-8-11-3-4-14(22)13(21)5-11)25-10-26-20(18)27-15(12)7-17(16)29-2/h3-7,10,23H,8-9H2,1-2H3,(H2,24,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192483 (1-(3-bromo-phenylsulfanyl)-7,8-dimethoxy-10,11-dih...) Show SMILES COc1cc2CNc3c(Sc4cccc(Br)c4)ncnc3Sc2cc1OC Show InChI InChI=1S/C19H16BrN3O2S2/c1-24-14-6-11-9-21-17-18(26-13-5-3-4-12(20)7-13)22-10-23-19(17)27-16(11)8-15(14)25-2/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180444 (CHEMBL203132 | N*1*-(3-Bromo-phenyl)-10,11-dihydro...) Show SMILES Nc1ccc2Oc3ncnc(Nc4cccc(Br)c4)c3NCc2c1 Show InChI InChI=1S/C17H14BrN5O/c18-11-2-1-3-13(7-11)23-16-15-17(22-9-21-16)24-14-5-4-12(19)6-10(14)8-20-15/h1-7,9,20H,8,19H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192478 (1-(3-bromo-phenoxy)-7,8-dimethoxy-10,11-dihydro-5-...) Show SMILES COc1cc2CNc3c(Oc4cccc(Br)c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C19H16BrN3O4/c1-24-15-6-11-9-21-17-18(26-13-5-3-4-12(20)7-13)22-10-23-19(17)27-14(11)8-16(15)25-2/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180445 ((3-Bromo-phenyl)-(7-methoxy-10,11-dihydro-5-oxa-2,...) Show SMILES COc1ccc2CNc3c(Nc4cccc(Br)c4)ncnc3Oc2c1 Show InChI InChI=1S/C18H15BrN4O2/c1-24-14-6-5-11-9-20-16-17(23-13-4-2-3-12(19)7-13)21-10-22-18(16)25-15(11)8-14/h2-8,10,20H,9H2,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192497 ((7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-...) Show SMILES COc1cccc(CNc2ncnc3Nc4cc(OC)c(OC)cc4CNc23)c1 Show InChI InChI=1S/C21H23N5O3/c1-27-15-6-4-5-13(7-15)10-23-20-19-21(25-12-24-20)26-16-9-18(29-3)17(28-2)8-14(16)11-22-19/h4-9,12,22H,10-11H2,1-3H3,(H2,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192498 ((3-chloro-4-fluoro-benzyl)-(7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(NCc4ccc(F)c(Cl)c4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H19ClFN5O2/c1-28-16-6-12-9-23-18-19(24-8-11-3-4-14(22)13(21)5-11)25-10-26-20(18)27-15(12)7-17(16)29-2/h3-7,10,23H,8-9H2,1-2H3,(H2,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180425 (Biphenyl-3-yl-(8-fluoro-10,11-dihydro-5-oxa-2,4,11...) Show SMILES Fc1ccc2Oc3ncnc(Nc4cccc(c4)-c4ccccc4)c3NCc2c1 Show InChI InChI=1S/C23H17FN4O/c24-18-9-10-20-17(11-18)13-25-21-22(26-14-27-23(21)29-20)28-19-8-4-7-16(12-19)15-5-2-1-3-6-15/h1-12,14,25H,13H2,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192487 ((7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-...) Show SMILES COc1cc2CNc3c(N[C@H](C)c4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C21H23N5O2/c1-13(14-7-5-4-6-8-14)25-20-19-21(24-12-23-20)26-16-10-18(28-3)17(27-2)9-15(16)11-22-19/h4-10,12-13,22H,11H2,1-3H3,(H2,23,24,25,26)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192474 (CHEMBL215191 | benzyl-(7,8-dimethoxy-10,11-dihydro...) Show SMILES COc1cc2CNc3c(NCc4ccccc4)ncnc3Nc2cc1OC Show InChI InChI=1S/C20H21N5O2/c1-26-16-8-14-11-21-18-19(22-10-13-6-4-3-5-7-13)23-12-24-20(18)25-15(14)9-17(16)27-2/h3-9,12,21H,10-11H2,1-2H3,(H2,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assay				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180423 ((8-Bromo-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo...) Show SMILES Fc1ccc(Nc2ncnc3Oc4ccc(Br)cc4CNc23)cc1Cl Show InChI InChI=1S/C17H11BrClFN4O/c18-10-1-4-14-9(5-10)7-21-15-16(22-8-23-17(15)25-14)24-11-2-3-13(20)12(19)6-11/h1-6,8,21H,7H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180427 (Benzyl-(8-methoxy-10,11-dihydro-5-oxa-2,4,11-triaz...) Show SMILES COc1ccc2Oc3ncnc(NCc4ccccc4)c3NCc2c1 Show InChI InChI=1S/C19H18N4O2/c1-24-15-7-8-16-14(9-15)11-20-17-18(22-12-23-19(17)25-16)21-10-13-5-3-2-4-6-13/h2-9,12,20H,10-11H2,1H3,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192471 ((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...) Show SMILES COc1cc2CNc3c(Nc4ccc5ccccc5c4)ncnc3Oc2cc1OC Show InChI InChI=1S/C23H20N4O3/c1-28-19-10-16-12-24-21-22(25-13-26-23(21)30-18(16)11-20(19)29-2)27-17-8-7-14-5-3-4-6-15(14)9-17/h3-11,13,24H,12H2,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180443 ((3-Chloro-4-fluoro-phenyl)-(8-methoxy-10,11-dihydr...) Show SMILES COc1ccc2Oc3ncnc(Nc4ccc(F)c(Cl)c4)c3NCc2c1 Show InChI InChI=1S/C18H14ClFN4O2/c1-25-12-3-5-15-10(6-12)8-21-16-17(22-9-23-18(16)26-15)24-11-2-4-14(20)13(19)7-11/h2-7,9,21H,8H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50192496 (1-(3-chloro-phenylsulfanyl)-7,8-dimethoxy-10,11-di...) Show SMILES COc1cc2CNc3c(Oc2cc1OC)ncnc3Sc1cccc(Cl)c1 Show InChI InChI=1S/C19H16ClN3O3S/c1-24-15-6-11-9-21-17-18(26-14(11)8-16(15)25-2)22-10-23-19(17)27-13-5-3-4-12(20)7-13/h3-8,10,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells by ELISA				Bioorg Med Chem Lett 16: 5102-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.031 BindingDB Entry DOI: 10.7270/Q2K9374T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50180441 ((3-Chloro-4-fluoro-phenyl)-(10,11-dihydro-5-oxa-2,...) Show SMILES Fc1ccc(Nc2ncnc3Oc4ccccc4CNc23)cc1Cl Show InChI InChI=1S/C17H12ClFN4O/c18-12-7-11(5-6-13(12)19)23-16-15-17(22-9-21-16)24-14-4-2-1-3-10(14)8-20-15/h1-7,9,20H,8H2,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of EGFR autophosphorylation in DiFi cells				Bioorg Med Chem Lett 16: 1643-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.018 BindingDB Entry DOI: 10.7270/Q2XP74JC
					More data for this Ligand-Target Pair

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