BindingDB PrimarySearch

Found 70 hits with Last Name = 'king' and Initial = 'sb'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50095201 ((S)-2-Amino-5-thioureido-pentanoic acid \| 2-Amino-...) Show SMILES N[C@@H](CCCNC(N)=S)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Compound was tested for the competitive inhibition of nitric oxide synthase (n) using [14C]-L-citrulline as radioligand.; value ranges from 0.06-2 mi...				Bioorg Med Chem Lett 10: 2779-81 (2000) BindingDB Entry DOI: 10.7270/Q2B27THQ
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50095201 ((S)-2-Amino-5-thioureido-pentanoic acid \| 2-Amino-...) Show SMILES N[C@@H](CCCNC(N)=S)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Compound was tested for the competitive inhibition of nitric oxide synthase (i) using [14C]-L-citrulline as radioligand. value ranges from 3.6-9 micr...				Bioorg Med Chem Lett 10: 2779-81 (2000) BindingDB Entry DOI: 10.7270/Q2B27THQ
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50077250 ((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...) Show SMILES CSC(NO)=NCCC[C@H](N)C(O)=O \|w:5.5\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50077251 ((2S)-2-amino-5-{[(1Z)-hydrazino(methylthio)methyle...) Show SMILES CSC(NCCC[C@H](N)C(O)=O)=NN \|w:12.12\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50077252 ((2S)-2-amino-5-[(hydrazinocarbonothioyl)amino]pent...) Show SMILES NNC(=S)NCCC[C@H](N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.02E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295043 ((E)-12-Nitrooctadec-12-enoic Acid \| CHEMBL549351) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase (Oryctolagus cuniculus)	BDBM50439262 (CHEMBL2419244) Show SMILES CC(C)(C)C(=O)OC1(CCCCC1)N=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometry				J Med Chem 56: 6583-92 (2013) Article DOI: 10.1021/jm400057r BindingDB Entry DOI: 10.7270/Q2PV6MSG
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339185 ((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid \| ...) Show SMILES COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295044 ((E)-13-Nitrooctadec-12-enoic Acid \| CHEMBL540732) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase (Oryctolagus cuniculus)	BDBM50439263 (1-NITROSOCYCLOHEXYL ACETATE) Show SMILES CC(=O)OC1(CCCCC1)N=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometry				J Med Chem 56: 6583-92 (2013) Article DOI: 10.1021/jm400057r BindingDB Entry DOI: 10.7270/Q2PV6MSG
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glyceraldehyde-3-phosphate dehydrogenase (Oryctolagus cuniculus)	BDBM50439264 (ANGELI'S SALT \| Angeli''s Salt) Show SMILES [O-]N([O-])N=O Show InChI InChI=1S/N2O3/c3-1-2(4)5/q-2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometry				J Med Chem 56: 6583-92 (2013) Article DOI: 10.1021/jm400057r BindingDB Entry DOI: 10.7270/Q2PV6MSG
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339180 (2-{2-[1-(4-Chlorobenzoyl)-2-methyl-5-methoxyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339184 (CHEMBL1689434 \| N-Methoxyl 2-[2-(4-Isobutylphenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295046 ((E)-10-Nitrohexadec-9-enoic Acid \| CHEMBL564368) Show SMILES CCCCCC\C(=C/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase (Oryctolagus cuniculus)	BDBM50439261 (1-NITROSOCYCLOHEXYL TRIFLUOROACETATE) Show SMILES FC(F)(F)C(=O)OC1(CCCCC1)N=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle GAPDH assessed as residual enzyme activity after 60 mins by spectrophotometry				J Med Chem 56: 6583-92 (2013) Article DOI: 10.1021/jm400057r BindingDB Entry DOI: 10.7270/Q2PV6MSG
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295047 ((E)-9-Nitrohexadec-9-enoicAcid \| CHEMBL560513) Show SMILES CCCCCC\C=C(/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295048 ((E)-9-nitrooctadec-9-enoic acid \| CHEMBL550762 \| N...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295044 ((E)-13-Nitrooctadec-12-enoic Acid \| CHEMBL540732) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339183 (2-[2-(4-Isobutylphenyl)propionoyloxy]ethanesulfony...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)OCCS(=O)(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295043 ((E)-12-Nitrooctadec-12-enoic Acid \| CHEMBL549351) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295049 ((E)-10-nitrooctadec-9-enoic acid \| CHEMBL561371) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295050 ((E)-5-Nitrooctadec-5-enoic Acid \| CHEMBL561776) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50295051 ((E)-6-Nitrooctadec-5-enoic Acid \| CHEMBL569372) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339181 ((S)-(+)-2-[2-(6-Methoxynaphthyl-2-yl)propionoyloxy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid \| (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339181 ((S)-(+)-2-[2-(6-Methoxynaphthyl-2-yl)propionoyloxy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50077250 ((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...) Show SMILES CSC(NO)=NCCC[C@H](N)C(O)=O \|w:5.5\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mamalian Neuronal nitric oxide synthase (nNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295045 ((9Z,12E)-12-nitrooctadeca-9,12-dienoic acid \| CHEM...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339185 ((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid \| ...) Show SMILES COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50077250 ((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...) Show SMILES CSC(NO)=NCCC[C@H](N)C(O)=O \|w:5.5\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mouse inducible nitric oxide synthase (iNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339184 (CHEMBL1689434 \| N-Methoxyl 2-[2-(4-Isobutylphenyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295046 ((E)-10-Nitrohexadec-9-enoic Acid \| CHEMBL564368) Show SMILES CCCCCC\C(=C/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295048 ((E)-9-nitrooctadec-9-enoic acid \| CHEMBL550762 \| N...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295049 ((E)-10-nitrooctadec-9-enoic acid \| CHEMBL561371) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295051 ((E)-6-Nitrooctadec-5-enoic Acid \| CHEMBL569372) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295050 ((E)-5-Nitrooctadec-5-enoic Acid \| CHEMBL561776) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50295047 ((E)-9-Nitrohexadec-9-enoicAcid \| CHEMBL560513) Show SMILES CCCCCC\C=C(/CCCCCCCC(O)=O)[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assay				J Med Chem 52: 4631-9 (2009) Article DOI: 10.1021/jm900326c BindingDB Entry DOI: 10.7270/Q2HQ3ZXB
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339183 (2-[2-(4-Isobutylphenyl)propionoyloxy]ethanesulfony...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)OCCS(=O)(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50077250 ((2S)-2-amino-5-{[(1Z)-(hydroxyamino)(methylthio)me...) Show SMILES CSC(NO)=NCCC[C@H](N)C(O)=O \|w:5.5\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against mamalian endothelial nitric oxide synthase (eNOS)				J Med Chem 42: 1842-8 (1999) Article DOI: 10.1021/jm980232x BindingDB Entry DOI: 10.7270/Q26D5S6Q
Wake Forest University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM7882 (1H-imidazole \| CHEMBL540 \| Imidazole (Im) \| US9138...) Show SMILES c1c[nH]cn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339180 (2-{2-[1-(4-Chlorobenzoyl)-2-methyl-5-methoxyl-1H-i...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339186 (CHEMBL1689435 \| Ethanesulfonylhydroxamic Acid) Show SMILES CCS(=O)(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50339182 (2-(Phenylacetyloxy)ethanesulfonylhydroxamic Acid \|...) Show SMILES ONS(=O)(=O)CCOC(=O)Cc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX-2				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50339186 (CHEMBL1689435 \| Ethanesulfonylhydroxamic Acid) Show SMILES CCS(=O)(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX-1				J Med Chem 54: 1356-64 (2011) Article DOI: 10.1021/jm101403g BindingDB Entry DOI: 10.7270/Q2RJ4KFB
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 70 total ) | Next | Last >>