Compile Data Set for Download or QSAR

Found 80 hits with Last Name = 'schmidt' and Initial = 'sp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024448 (5-Hydroxycarbamoylmethyl-icosa-6,8,11,14-tetraenoi...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(CCCC(O)=O)CC(=O)NO Show InChI InChI=1S/C22H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-20(19-21(24)23-27)17-15-18-22(25)26/h6-7,9-10,12-14,16,20,27H,2-5,8,11,15,17-19H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280197 (1-(3-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL3024...) Show SMILES Clc1cccc(c1)N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-2-1-3-8(6-7)12-5-4-9(13)11-12/h1-3,6H,4-5H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280185 (1-(4-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL2960...) Show SMILES Clc1ccc(cc1)N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-1-3-8(4-2-7)12-6-5-9(13)11-12/h1-4H,5-6H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280192 (1-m-Tolyl-pyrazolidin-3-one | CHEMBL26084) Show SMILES Cc1cccc(c1)N1CCC(=O)N1 Show InChI InChI=1S/C10H12N2O/c1-8-3-2-4-9(7-8)12-6-5-10(13)11-12/h2-4,7H,5-6H2,1H3,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) Show SMILES NC1=NN(CC1)c1cccc(c1)C(F)(F)F |t:1| Show InChI InChI=1S/C10H10F3N3/c11-10(12,13)7-2-1-3-8(6-7)16-5-4-9(14)15-16/h1-3,6H,4-5H2,(H2,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024444 (5-Hydroxycarbamoyl-icosa-6,8,11,14-tetraenoic acid...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(CCCC(O)=O)C(=O)NO Show InChI InChI=1S/C21H33NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21(25)22-26)17-15-18-20(23)24/h6-7,9-10,12-14,16,19,26H,2-5,8,11,15,17-18H2,1H3,(H,22,25)(H,23,24)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280165 (2-(4-Butyl-phenyl)-indan-1,3-dione | CHEMBL25994) Show SMILES CCCCc1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C19H18O2/c1-2-3-6-13-9-11-14(12-10-13)17-18(20)15-7-4-5-8-16(15)19(17)21/h4-5,7-12,17H,2-3,6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280170 (2-Fluoro-2-phenyl-indan-1,3-dione | CHEMBL24960) Show SMILES FC1(C(=O)c2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C15H9FO2/c16-15(10-6-2-1-3-7-10)13(17)11-8-4-5-9-12(11)14(15)18/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280176 (1-(3-Bromo-phenyl)-tetrahydro-pyridazin-3-one | CH...) Show SMILES Brc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C10H11BrN2O/c11-8-3-1-4-9(7-8)13-6-2-5-10(14)12-13/h1,3-4,7H,2,5-6H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280161 (2-Fluoro-2-naphthalen-2-yl-indan-1,3-dione | CHEMB...) Show SMILES FC1(C(=O)c2ccccc2C1=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H11FO2/c20-19(14-10-9-12-5-1-2-6-13(12)11-14)17(21)15-7-3-4-8-16(15)18(19)22/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024460 ((6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(=O)NO Show InChI InChI=1S/C20H33NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17-15-18-20(23)21-24/h6-7,9-10,12-14,16,19,22,24H,2-5,8,11,15,17-18H2,1H3,(H,21,23)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024446 ((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid hy...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NO Show InChI InChI=1S/C20H33NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(22)21-23/h6-7,9-10,12-13,15-16,23H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280154 (5-Bromo-2-fluoro-2-phenyl-indan-1,3-dione | CHEMBL...) Show SMILES FC1(C(=O)c2ccc(Br)cc2C1=O)c1ccccc1 Show InChI InChI=1S/C15H8BrFO2/c16-10-6-7-11-12(8-10)14(19)15(17,13(11)18)9-4-2-1-3-5-9/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280196 (1-(3-Chloro-phenyl)-tetrahydro-pyridazin-3-one | C...) Show SMILES Clc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C10H11ClN2O/c11-8-3-1-4-9(7-8)13-6-2-5-10(14)12-13/h1,3-4,7H,2,5-6H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280158 (2-(4-Methylsulfanyl-phenyl)-indan-1,3-dione | CHEM...) Show SMILES CSc1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H12O2S/c1-19-11-8-6-10(7-9-11)14-15(17)12-4-2-3-5-13(12)16(14)18/h2-9,14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024449 (5-(2-Hydroxycarbamoyl-ethyl)-icosa-6,8,11,14-tetra...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(CCCC(O)=O)CCC(=O)NO Show InChI InChI=1S/C23H37NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(17-15-18-23(26)27)19-20-22(25)24-28/h6-7,9-10,12-14,16,21,28H,2-5,8,11,15,17-20H2,1H3,(H,24,25)(H,26,27)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280164 (2-(3,5-Di-tert-butyl-phenyl)-indan-1,3-dione | CHE...) Show SMILES CC(C)(C)c1cc(cc(c1)C(C)(C)C)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C23H26O2/c1-22(2,3)15-11-14(12-16(13-15)23(4,5)6)19-20(24)17-9-7-8-10-18(17)21(19)25/h7-13,19H,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280180 (1-(3-Ethyl-phenyl)-tetrahydro-pyridazin-3-one | CH...) Show SMILES CCc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C12H16N2O/c1-2-10-5-3-6-11(9-10)14-8-4-7-12(15)13-14/h3,5-6,9H,2,4,7-8H2,1H3,(H,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280163 (2-Naphthalen-2-yl-indan-1,3-dione | CHEMBL282063) Show SMILES O=C1C(C(=O)c2ccccc12)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H12O2/c20-18-15-7-3-4-8-16(15)19(21)17(18)14-10-9-12-5-1-2-6-13(12)11-14/h1-11,17H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280175 (1-m-Tolyl-tetrahydro-pyridazin-3-one | CHEMBL30151) Show SMILES Cc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C11H14N2O/c1-9-4-2-5-10(8-9)13-7-3-6-11(14)12-13/h2,4-5,8H,3,6-7H2,1H3,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280198 (1-p-Tolyl-pyrazolidin-3-one | CHEMBL29508) Show SMILES Cc1ccc(cc1)N1CCC(=O)N1 Show InChI InChI=1S/C10H12N2O/c1-8-2-4-9(5-3-8)12-7-6-10(13)11-12/h2-5H,6-7H2,1H3,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280177 (1-(2-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL2850...) Show SMILES Clc1ccccc1N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-3-1-2-4-8(7)12-6-5-9(13)11-12/h1-4H,5-6H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009941 (1-Phenyl-tetrahydro-pyridazin-3-one | CHEMBL30110) Show SMILES O=C1CCCN(N1)c1ccccc1 Show InChI InChI=1S/C10H12N2O/c13-10-7-4-8-12(11-10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280168 (2-(4-Dimethylamino-phenyl)-indan-1,3-dione | CHEMB...) Show SMILES CN(C)c1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C17H15NO2/c1-18(2)12-9-7-11(8-10-12)15-16(19)13-5-3-4-6-14(13)17(15)20/h3-10,15H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280159 (2-Phenyl-2-phenylsulfanyl-indan-1,3-dione | CHEMBL...) Show SMILES O=C1c2ccccc2C(=O)C1(Sc1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H14O2S/c22-19-17-13-7-8-14-18(17)20(23)21(19,15-9-3-1-4-10-15)24-16-11-5-2-6-12-16/h1-14H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280162 (2-(4-Chloro-phenyl)-indan-1,3-dione | CHEMBL278519...) Show SMILES Clc1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C15H9ClO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280178 (1-(3-Trifluoromethyl-phenyl)-tetrahydro-pyridazin-...) Show SMILES FC(F)(F)c1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C11H11F3N2O/c12-11(13,14)8-3-1-4-9(7-8)16-6-2-5-10(17)15-16/h1,3-4,7H,2,5-6H2,(H,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280174 (1-(3-Fluoro-phenyl)-tetrahydro-pyridazin-3-one | C...) Show SMILES Fc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C10H11FN2O/c11-8-3-1-4-9(7-8)13-6-2-5-10(14)12-13/h1,3-4,7H,2,5-6H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280199 (3-(3-Oxo-tetrahydro-pyridazin-1-yl)-benzoic acid e...) Show SMILES CCOC(=O)c1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C13H16N2O3/c1-2-18-13(17)10-5-3-6-11(9-10)15-8-4-7-12(16)14-15/h3,5-6,9H,2,4,7-8H2,1H3,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280183 (1-Dodecyl-tetrahydro-pyridazin-3-one | CHEMBL25790) Show SMILES CCCCCCCCCCCCN1CCCC(=O)N1 Show InChI InChI=1S/C16H32N2O/c1-2-3-4-5-6-7-8-9-10-11-14-18-15-12-13-16(19)17-18/h2-15H2,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280173 (1-(3-Methoxy-phenyl)-tetrahydro-pyridazin-3-one | ...) Show SMILES COc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C11H14N2O2/c1-15-10-5-2-4-9(8-10)13-7-3-6-11(14)12-13/h2,4-5,8H,3,6-7H2,1H3,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024450 (5-semicarbazone-hydrazone-icosa-6,8,11,14-tetraeno...) Show SMILES CCCCC\C=C/C\C=C/CC=CC=CC(CCCC(O)=O)=NNC(N)=O |w:22.22,13.12,11.10| Show InChI InChI=1S/C21H33N3O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(23-24-21(22)27)17-15-18-20(25)26/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,25,26)(H3,22,24,27)/b7-6-,10-9-,13-12?,16-14?,23-19?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024443 (15-Hydroxy-icosa-6,8,11,14-tetraenoic acid(15-HETE...) Show SMILES CCCCCC(=O)CC\C=C/C\C=C/C=C/CCCCC(O)=O Show InChI InChI=1S/C20H32O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-6,8-9,11H,2-3,7,10,12-18H2,1H3,(H,22,23)/b5-4-,8-6+,11-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024457 (5-Mercapto-icosa-6,8,11,14-tetraenoic acid | CHEMB...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(S)CCCC(O)=O Show InChI InChI=1S/C20H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(23)17-15-18-20(21)22/h6-7,9-10,12-14,16,19,23H,2-5,8,11,15,17-18H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024454 (5-thiosemicarbazone-hydrazone-icosa-6,8,11,14-tetr...) Show SMILES CCCCC\C=C/C\C=C/CC=CC=CC(CCCC(O)=O)=NNC(N)=S |w:22.22,13.12,11.10| Show InChI InChI=1S/C21H33N3O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(23-24-21(22)27)17-15-18-20(25)26/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,25,26)(H3,22,24,27)/b7-6-,10-9-,13-12?,16-14?,23-19?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280202 (1-o-Tolyl-pyrazolidin-3-one | CHEMBL26143) Show SMILES Cc1ccccc1N1CCC(=O)N1 Show InChI InChI=1S/C10H12N2O/c1-8-4-2-3-5-9(8)12-7-6-10(13)11-12/h2-5H,6-7H2,1H3,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280155 (2-(4-Methoxy-phenyl)-indan-1,3-dione | ANISINDIONE...) Show SMILES COc1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C16H12O3/c1-19-11-8-6-10(7-9-11)14-15(17)12-4-2-3-5-13(12)16(14)18/h2-9,14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280187 (3-(3-Oxo-tetrahydro-pyridazin-1-yl)-benzonitrile |...) Show SMILES O=C1CCCN(N1)c1cccc(c1)C#N Show InChI InChI=1S/C11H11N3O/c12-8-9-3-1-4-10(7-9)14-6-2-5-11(15)13-14/h1,3-4,7H,2,5-6H2,(H,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280156 (2-(4-Fluoro-phenyl)-indan-1,3-dione | CHEMBL24924 ...) Show SMILES Fc1ccc(cc1)C1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024438 (2-Oxo-6-((1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C1CCCC(=O)N1 Show InChI InChI=1S/C20H31NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(22)21-19/h6-7,9-10,12-14,16,19H,2-5,8,11,15,17-18H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024459 (5-Hydroxyimino-icosa-6,8,11,14-tetraenoic acid | C...) Show SMILES CCCCC\C=C/C\C=C/CC=CC=CC(CCCC(O)=O)N=O |w:13.12,11.10| Show InChI InChI=1S/C20H31NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21-24)17-15-18-20(22)23/h6-7,9-10,12-14,16,19H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12?,16-14?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024441 (5-Mercaptomethyl-icosa-6,8,11,14-tetraenoic acid |...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(CS)CCCC(O)=O Show InChI InChI=1S/C21H34O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-20(19-24)17-15-18-21(22)23/h6-7,9-10,12-14,16,20,24H,2-5,8,11,15,17-19H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280169 (2-(4-Butyl-phenyl)-cyclooctane-1,3-dione | CHEMBL2...) Show SMILES CCCCc1ccc(cc1)C1C(=O)CCCCCC1=O Show InChI InChI=1S/C18H24O2/c1-2-3-7-14-10-12-15(13-11-14)18-16(19)8-5-4-6-9-17(18)20/h10-13,18H,2-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280188 (1-[3-(2,2-Dimethyl-propionyl)-phenyl]-tetrahydro-p...) Show SMILES CC(C)(C)C(=O)c1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C15H20N2O2/c1-15(2,3)14(19)11-6-4-7-12(10-11)17-9-5-8-13(18)16-17/h4,6-7,10H,5,8-9H2,1-3H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280157 (2-Phenyl-1,3-indandione | 2-phenyl-1,3(2H)-Indened...) Show SMILES O=C1C(C(=O)c2ccccc12)c1ccccc1 Show InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50280171 (2-Methylsulfanyl-2-phenyl-indan-1,3-dione | CHEMBL...) Show SMILES CSC1(C(=O)c2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C16H12O2S/c1-19-16(11-7-3-2-4-8-11)14(17)12-9-5-6-10-13(12)15(16)18/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase activity in RBL-1 cells.				Bioorg Med Chem Lett 2: 1309-1314 (1992) Article DOI: 10.1016/S0960-894X(00)80236-X BindingDB Entry DOI: 10.7270/Q2RN37RW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024458 (5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo) Show SMILES CCCCC\C=C/C\C=C/CC=CC=CC(=O)CCCC(O)=O |w:13.12,11.10| Show InChI InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12?,16-14?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair

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