Compile Data Set for Download or QSAR

Found 133 hits with Last Name = 'ikeo' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50066454 (CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...) Show SMILES [O-]C(=O)C1CCN(CC1)c1nc(NCc2ccc3OCOc3c2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C22H21ClN4O4/c23-15-2-3-17-16(10-15)20(24-11-13-1-4-18-19(9-13)31-12-30-18)26-22(25-17)27-7-5-14(6-8-27)21(28)29/h1-4,9-10,14H,5-8,11-12H2,(H,28,29)(H,24,25,26)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075691 (1-(3-Bromo-4,5-dimethoxy-phenyl)-5-chloro-3-[4-(2-...) Show SMILES COC(=O)c1c(cc2c(Cl)cccc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H28BrClN2O6/c1-35-22-14-16(13-20(28)25(22)36-2)23-17-5-4-6-21(29)18(17)15-19(24(23)27(34)37-3)26(33)31-9-7-30(8-10-31)11-12-32/h4-6,13-15,32H,7-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075686 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2cc(OC)ccc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31BrN2O7/c1-35-19-5-6-20-17(13-19)14-21(27(33)31-9-7-30(8-10-31)11-12-32)25(28(34)38-4)24(20)18-15-22(29)26(37-3)23(16-18)36-2/h5-6,13-16,32H,7-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075698 (1-(3-Bromo-4,5-dimethoxy-phenyl)-6-ethoxy-3-[4-(2-...) Show SMILES CCOc1cc2cc(C(=O)N3CCN(CCO)CC3)c(C(=O)OC)c(-c3cc(Br)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C30H35BrN2O8/c1-6-41-24-15-18-13-21(29(35)33-9-7-32(8-10-33)11-12-34)27(30(36)40-5)26(20(18)17-23(24)37-2)19-14-22(31)28(39-4)25(16-19)38-3/h13-17,34H,6-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075713 (1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-...) Show SMILES COC(=O)c1c(cc2ccc(Cl)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H28BrClN2O6/c1-35-22-14-17(13-21(28)25(22)36-2)23-19-15-18(29)5-4-16(19)12-20(24(23)27(34)37-3)26(33)31-8-6-30(7-9-31)10-11-32/h4-5,12-15,32H,6-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075684 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H33BrN2O8/c1-36-22-14-17-12-20(28(34)32-8-6-31(7-9-32)10-11-33)26(29(35)40-5)25(19(17)16-23(22)37-2)18-13-21(30)27(39-4)24(15-18)38-3/h12-16,33H,6-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075693 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2ccccc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H29BrN2O6/c1-34-22-16-18(15-21(28)25(22)35-2)23-19-7-5-4-6-17(19)14-20(24(23)27(33)36-3)26(32)30-10-8-29(9-11-30)12-13-31/h4-7,14-16,31H,8-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075705 (1-(3-Chloro-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(Cl)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H33ClN2O8/c1-36-22-14-17-12-20(28(34)32-8-6-31(7-9-32)10-11-33)26(29(35)40-5)25(19(17)16-23(22)37-2)18-13-21(30)27(39-4)24(15-18)38-3/h12-16,33H,6-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075716 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2ccc(C)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31BrN2O6/c1-17-5-6-18-14-21(27(33)31-9-7-30(8-10-31)11-12-32)25(28(34)37-4)24(20(18)13-17)19-15-22(29)26(36-3)23(16-19)35-2/h5-6,13-16,32H,7-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075695 (6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2COC(=O)c2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-17-7-12-6-15-16(11-30-23(15)24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075687 (3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C30H36N2O9/c1-36-22-14-18-13-21(29(34)32-9-7-31(8-10-32)11-12-33)27(30(35)41-6)26(20(18)17-23(22)37-2)19-15-24(38-3)28(40-5)25(16-19)39-4/h13-17,33H,7-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075708 (3-(4-Hydroxy-piperidine-1-carbonyl)-6,7-dimethoxy-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCC(O)CC1 Show InChI InChI=1S/C29H33NO9/c1-34-21-12-16-11-20(28(32)30-9-7-18(31)8-10-30)26(29(33)39-6)25(19(16)15-22(21)35-2)17-13-23(36-3)27(38-5)24(14-17)37-4/h11-15,18,31H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075711 (3-Dimethylcarbamoyl-6,7-dimethoxy-1-(3,4,5-trimeth...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N(C)C Show InChI InChI=1S/C26H29NO8/c1-27(2)25(28)17-9-14-10-18(30-3)19(31-4)13-16(14)22(23(17)26(29)35-8)15-11-20(32-5)24(34-7)21(12-15)33-6/h9-13H,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50052090 (6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2C(=O)OCc2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-16-7-12-6-14-11-30-23(24)21(14)20(15(12)10-17(16)26-2)13-8-18(27-3)22(29-5)19(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50075710 (3-Carbamoyl-6,7-dimethoxy-1-(3,4,5-trimethoxy-phen...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(N)=O Show InChI InChI=1S/C24H25NO8/c1-28-16-8-12-7-15(23(25)26)21(24(27)33-6)20(14(12)11-17(16)29-2)13-9-18(30-3)22(32-5)19(10-13)31-4/h7-11H,1-6H3,(H2,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075685 (3-(4-Hydroxymethyl-piperidine-1-carbonyl)-6,7-dime...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCC(CO)CC1 Show InChI InChI=1S/C30H35NO9/c1-35-22-12-18-11-21(29(33)31-9-7-17(16-32)8-10-31)27(30(34)40-6)26(20(18)15-23(22)36-2)19-13-24(37-3)28(39-5)25(14-19)38-4/h11-15,17,32H,7-10,16H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075699 (6,7-Dimethoxy-3-(morpholine-4-carbonyl)-1-(3,4,5-t...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C28H31NO9/c1-32-20-12-16-11-19(27(30)29-7-9-38-10-8-29)25(28(31)37-6)24(18(16)15-21(20)33-2)17-13-22(34-3)26(36-5)23(14-17)35-4/h11-15H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075695 (6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2COC(=O)c2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-17-7-12-6-15-16(11-30-23(15)24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075702 (6,7-Dimethoxy-3-(4-oxo-piperidine-1-carbonyl)-1-(3...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCC(=O)CC1 Show InChI InChI=1S/C29H31NO9/c1-34-21-12-16-11-20(28(32)30-9-7-18(31)8-10-30)26(29(33)39-6)25(19(16)15-22(21)35-2)17-13-23(36-3)27(38-5)24(14-17)37-4/h11-15H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075703 (6,7-Dimethoxy-3-(pyrrolidine-1-carbonyl)-1-(3,4,5-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCCC1 Show InChI InChI=1S/C28H31NO8/c1-32-20-12-16-11-19(27(30)29-9-7-8-10-29)25(28(31)37-6)24(18(16)15-21(20)33-2)17-13-22(34-3)26(36-5)23(14-17)35-4/h11-15H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50052090 (6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2C(=O)OCc2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-16-7-12-6-14-11-30-23(24)21(14)20(15(12)10-17(16)26-2)13-8-18(27-3)22(29-5)19(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075710 (3-Carbamoyl-6,7-dimethoxy-1-(3,4,5-trimethoxy-phen...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(N)=O Show InChI InChI=1S/C24H25NO8/c1-28-16-8-12-7-15(23(25)26)21(24(27)33-6)20(14(12)11-17(16)29-2)13-9-18(30-3)22(32-5)19(10-13)31-4/h7-11H,1-6H3,(H2,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50075695 (6,7-Dimethoxy-4-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2COC(=O)c2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-17-7-12-6-15-16(11-30-23(15)24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50052098 (CHEMBL285361 | [3-Hydroxymethyl-6,7-dimethoxy-1-(3...) Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C23H26O7/c1-26-18-7-13-6-15(11-24)17(12-25)22(16(13)10-19(18)27-2)14-8-20(28-3)23(30-5)21(9-14)29-4/h6-10,24-25H,11-12H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075713 (1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-...) Show SMILES COC(=O)c1c(cc2ccc(Cl)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H28BrClN2O6/c1-35-22-14-17(13-21(28)25(22)36-2)23-19-15-18(29)5-4-16(19)12-20(24(23)27(34)37-3)26(33)31-8-6-30(7-9-31)10-11-32/h4-5,12-15,32H,6-11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075706 (6,7-Dimethoxy-3-(4-methyl-piperazine-1-carbonyl)-1...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C29H34N2O8/c1-30-8-10-31(11-9-30)28(32)20-12-17-13-21(34-2)22(35-3)16-19(17)25(26(20)29(33)39-7)18-14-23(36-4)27(38-6)24(15-18)37-5/h12-16H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075704 (1-[6,7-Dimethoxy-3-methoxycarbonyl-4-(3,4,5-trimet...) Show SMILES CCOC(=O)C1CCN(CC1)C(=O)c1cc2cc(OC)c(OC)cc2c(-c2cc(OC)c(OC)c(OC)c2)c1C(=O)OC Show InChI InChI=1S/C32H37NO10/c1-8-43-31(35)18-9-11-33(12-10-18)30(34)22-13-19-14-23(37-2)24(38-3)17-21(19)27(28(22)32(36)42-7)20-15-25(39-4)29(41-6)26(16-20)40-5/h13-18H,8-12H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075683 (6,7-Dimethoxy-1-(3,4,5-trimethoxy-phenyl)-naphthal...) Show SMILES COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2cc(OC)c(OC)c(OC)c2)c1C(=O)OC Show InChI InChI=1S/C25H26O9/c1-28-17-9-13-8-16(24(26)33-6)22(25(27)34-7)21(15(13)12-18(17)29-2)14-10-19(30-3)23(32-5)20(11-14)31-4/h8-12H,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075688 (6,7-Dimethoxy-3-(piperidine-1-carbonyl)-1-(3,4,5-t...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCCCC1 Show InChI InChI=1S/C29H33NO8/c1-33-21-13-17-12-20(28(31)30-10-8-7-9-11-30)26(29(32)38-6)25(19(17)16-22(21)34-2)18-14-23(35-3)27(37-5)24(15-18)36-4/h12-16H,7-11H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075712 (CHEMBL25423 | [3-Amino-6,7-dimethoxy-1-(3,4,5-trim...) Show SMILES COc1cc2cc(N)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C22H25NO6/c1-25-17-7-12-6-16(23)15(11-24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10,24H,11,23H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075701 (3-[4-(2-Hydroxy-ethyl)-piperazin-1-ylmethyl]-6,7-d...) Show SMILES COC(=O)c1c(CN2CCN(CCO)CC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C30H38N2O8/c1-35-23-14-19-13-21(18-32-9-7-31(8-10-32)11-12-33)28(30(34)40-6)27(22(19)17-24(23)36-2)20-15-25(37-3)29(39-5)26(16-20)38-4/h13-17,33H,7-12,18H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50075714 (6,7-Dimethoxy-3-methylcarbamoyl-1-(3,4,5-trimethox...) Show SMILES CNC(=O)c1cc2cc(OC)c(OC)cc2c(-c2cc(OC)c(OC)c(OC)c2)c1C(=O)OC Show InChI InChI=1S/C25H27NO8/c1-26-24(27)16-8-13-9-17(29-2)18(30-3)12-15(13)21(22(16)25(28)34-7)14-10-19(31-4)23(33-6)20(11-14)32-5/h8-12H,1-7H3,(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50066454 (CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...) Show SMILES [O-]C(=O)C1CCN(CC1)c1nc(NCc2ccc3OCOc3c2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C22H21ClN4O4/c23-15-2-3-17-16(10-15)20(24-11-13-1-4-18-19(9-13)31-12-30-18)26-22(25-17)27-7-5-14(6-8-27)21(28)29/h1-4,9-10,14H,5-8,11-12H2,(H,28,29)(H,24,25,26)/p-1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of canine lung Phosphodiesterase 4				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075693 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2ccccc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H29BrN2O6/c1-34-22-16-18(15-21(28)25(22)35-2)23-19-7-5-4-6-17(19)14-20(24(23)27(33)36-3)26(32)30-10-8-29(9-11-30)12-13-31/h4-7,14-16,31H,8-13H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075716 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2ccc(C)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31BrN2O6/c1-17-5-6-18-14-21(27(33)31-9-7-30(8-10-31)11-12-32)25(28(34)37-4)24(20(18)13-17)19-15-22(29)26(36-3)23(16-19)35-2/h5-6,13-16,32H,7-12H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50075712 (CHEMBL25423 | [3-Amino-6,7-dimethoxy-1-(3,4,5-trim...) Show SMILES COc1cc2cc(N)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C22H25NO6/c1-25-17-7-12-6-16(23)15(11-24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10,24H,11,23H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50066454 (CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...) Show SMILES [O-]C(=O)C1CCN(CC1)c1nc(NCc2ccc3OCOc3c2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C22H21ClN4O4/c23-15-2-3-17-16(10-15)20(24-11-13-1-4-18-19(9-13)31-12-30-18)26-22(25-17)27-7-5-14(6-8-27)21(28)29/h1-4,9-10,14H,5-8,11-12H2,(H,28,29)(H,24,25,26)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50052090 (6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...) Show SMILES COc1cc(cc(OC)c1OC)-c1c2C(=O)OCc2cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C23H22O7/c1-25-16-7-12-6-14-11-30-23(24)21(14)20(15(12)10-17(16)26-2)13-8-18(27-3)22(29-5)19(9-13)28-4/h6-10H,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075684 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H33BrN2O8/c1-36-22-14-17-12-20(28(34)32-8-6-31(7-9-32)10-11-33)26(29(35)40-5)25(19(17)16-23(22)37-2)18-13-21(30)27(39-4)24(15-18)38-3/h12-16,33H,6-11H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075690 (3-[4-(2-Hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1\C=C\c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C32H38N2O9/c1-38-25-18-21-17-24(31(36)34-11-9-33(10-12-34)13-14-35)29(32(37)43-6)22(23(21)19-26(25)39-2)8-7-20-15-27(40-3)30(42-5)28(16-20)41-4/h7-8,15-19,35H,9-14H2,1-6H3/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075686 (1-(3-Bromo-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-e...) Show SMILES COC(=O)c1c(cc2cc(OC)ccc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C28H31BrN2O7/c1-35-19-5-6-20-17(13-19)14-21(27(33)31-9-7-30(8-10-31)11-12-32)25(28(34)38-4)24(20)18-15-22(29)26(37-3)23(16-18)36-2/h5-6,13-16,32H,7-12H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50075712 (CHEMBL25423 | [3-Amino-6,7-dimethoxy-1-(3,4,5-trim...) Show SMILES COc1cc2cc(N)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C22H25NO6/c1-25-17-7-12-6-16(23)15(11-24)21(14(12)10-18(17)26-2)13-8-19(27-3)22(29-5)20(9-13)28-4/h6-10,24H,11,23H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Canis lupus familiaris)	BDBM50052098 (CHEMBL285361 | [3-Hydroxymethyl-6,7-dimethoxy-1-(3...) Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C23H26O7/c1-26-18-7-13-6-15(11-24)17(12-25)22(16(13)10-19(18)27-2)14-8-20(28-3)23(30-5)21(9-14)29-4/h6-10,24-25H,11-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50066454 (CHEMBL25616 | Sodium; 1-{4-[(benzo[1,3]dioxol-5-yl...) Show SMILES [O-]C(=O)C1CCN(CC1)c1nc(NCc2ccc3OCOc3c2)c2cc(Cl)ccc2n1 Show InChI InChI=1S/C22H21ClN4O4/c23-15-2-3-17-16(10-15)20(24-11-13-1-4-18-19(9-13)31-12-30-18)26-22(25-17)27-7-5-14(6-8-27)21(28)29/h1-4,9-10,14H,5-8,11-12H2,(H,28,29)(H,24,25,26)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of canine adrenal gland Phosphodiesterase 2				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50075711 (3-Dimethylcarbamoyl-6,7-dimethoxy-1-(3,4,5-trimeth...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N(C)C Show InChI InChI=1S/C26H29NO8/c1-27(2)25(28)17-9-14-10-18(30-3)19(31-4)13-16(14)22(23(17)26(29)35-8)15-11-20(32-5)24(34-7)21(12-15)33-6/h9-13H,1-8H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50052098 (CHEMBL285361 | [3-Hydroxymethyl-6,7-dimethoxy-1-(3...) Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(OC)c3)c2cc1OC Show InChI InChI=1S/C23H26O7/c1-26-18-7-13-6-15(11-24)17(12-25)22(16(13)10-19(18)27-2)14-8-20(28-3)23(30-5)21(9-14)29-4/h6-10,24-25H,11-12H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075704 (1-[6,7-Dimethoxy-3-methoxycarbonyl-4-(3,4,5-trimet...) Show SMILES CCOC(=O)C1CCN(CC1)C(=O)c1cc2cc(OC)c(OC)cc2c(-c2cc(OC)c(OC)c(OC)c2)c1C(=O)OC Show InChI InChI=1S/C32H37NO10/c1-8-43-31(35)18-9-11-33(12-10-18)30(34)22-13-19-14-23(37-2)24(38-3)17-21(19)27(28(22)32(36)42-7)20-15-25(39-4)29(41-6)26(16-20)40-5/h13-18H,8-12H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075705 (1-(3-Chloro-4,5-dimethoxy-phenyl)-3-[4-(2-hydroxy-...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(Cl)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1 Show InChI InChI=1S/C29H33ClN2O8/c1-36-22-14-17-12-20(28(34)32-8-6-31(7-9-32)10-11-33)26(29(35)40-5)25(19(17)16-23(22)37-2)18-13-21(30)27(39-4)24(15-18)38-3/h12-16,33H,6-11H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075701 (3-[4-(2-Hydroxy-ethyl)-piperazin-1-ylmethyl]-6,7-d...) Show SMILES COC(=O)c1c(CN2CCN(CCO)CC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C30H38N2O8/c1-35-23-14-19-13-21(18-32-9-7-31(8-10-32)11-12-33)28(30(34)40-6)27(22(19)17-24(23)36-2)20-15-25(37-3)29(39-5)26(16-20)38-4/h13-17,33H,7-12,18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM50075688 (6,7-Dimethoxy-3-(piperidine-1-carbonyl)-1-(3,4,5-t...) Show SMILES COC(=O)c1c(cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1)C(=O)N1CCCCC1 Show InChI InChI=1S/C29H33NO8/c1-33-21-13-17-12-20(28(31)30-10-8-7-9-11-30)26(29(32)38-6)25(19(17)16-22(21)34-2)18-14-23(35-3)27(37-5)24(15-18)36-4/h12-16H,7-11H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricle				J Med Chem 42: 1293-305 (1999) Article DOI: 10.1021/jm9807048 BindingDB Entry DOI: 10.7270/Q27P8XKH
					More data for this Ligand-Target Pair

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