BindingDB PrimarySearch

Found 191 hits with Last Name = 'iwanaga' and Initial = 't'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311264 (4-(3-(4-methoxy-3-nitrophenyl)-1H-1,2,4-triazol-5-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50254496 (4-(3-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587492 (CHEMBL5079107) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587502 (CHEMBL5079949) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311262 (4-(3-(4-chloro-3-nitrophenyl)-1H-1,2,4-triazol-5-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311266 (2-isobutoxy-5-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587504 (CHEMBL5087040) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311275 (4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)picolino...) Show SMILES N#Cc1cc(ccn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587505 (CHEMBL5072731) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587493 (CHEMBL5087238) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311279 (2-phenyl-4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311276 (2-chloro-4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl...) Show SMILES Clc1cc(ccn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587503 (CHEMBL5089800) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311277 (2-bromo-4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)...) Show SMILES Brc1cc(ccn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50254554 (4-(3-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587504 (CHEMBL5087040) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587501 (CHEMBL5092915) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311265 (4-(3-(4-methoxy-3-nitrophenyl)-1H-1,2,4-triazol-5-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50254499 (2-isobutoxy-5-(5-(2-methylpyridin-4-yl)-1H-1,2,4-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587494 (CHEMBL5090085) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587505 (CHEMBL5072731) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311274 (4,4'-(1H-1,2,4-triazole-3,5-diyl)dipicolinonitrile...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587492 (CHEMBL5079107) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311285 (2-isobutoxy-5-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3...) Show SMILES CC(C)COc1ccc(cn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311282 (2-methyl-4-(3-(pyridin-4-yl)-1H-1,2,4-triazol-5-yl...) Show SMILES Cc1cc(ccn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311263 (4-(3-(4-chloro-3-nitrophenyl)-1H-1,2,4-triazol-5-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50254503 (2-(2-(2-methoxyethoxy)ethoxy)-5-(3-(2-methylpyridi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587493 (CHEMBL5087238) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of URAT1 (unknown origin) transfected in dog MDCK cells assessed as inhibition of [14C]uric acid uptake by liquid scintillation counting m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50236530 (CHEMBL3727577) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK1 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50236518 (CHEMBL3732469) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50561689 (Dotinurad \| Fyu-981) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human URAT1 expressed in Xenopus laevis oocytes assessed as inhibition of [14C]uric acid uptake measured after 60 mins by liquid scinti...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311284 (5-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)picolino...) Show SMILES N#Cc1ccc(cn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311273 (4-(5-(2-chloropyridin-4-yl)-1H-1,2,4-triazol-3-yl)...) Show SMILES Clc1cc(ccn1)-c1nnc([nH]1)-c1ccnc(c1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587503 (CHEMBL5089800) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C9 (unknown origin)				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00176 BindingDB Entry DOI: 10.7270/Q2TQ6587
TBA					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP2C9 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127900 BindingDB Entry DOI: 10.7270/Q2P55S6N
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311272 (4-(3-(6-(isobutylthio)pyridin-3-yl)-1H-1,2,4-triaz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311278 (2-fluoro-4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl...) Show SMILES Fc1cc(ccn1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587490 (CHEMBL5080906) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311270 (2-methyl-4-(5-(2-phenylpyridin-4-yl)-1H-1,2,4-tria...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311268 (4-(3-(2-methylpyridin-4-yl)-1H-1,2,4-triazol-5-yl)...) Show SMILES Cc1cc(ccn1)-c1nnc([nH]1)-c1ccnc(c1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Homo sapiens (Human))	BDBM50587494 (CHEMBL5090085) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311271 (2-isobutoxy-4-(3-(2-methylpyridin-4-yl)-1H-1,2,4-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50236518 (CHEMBL3732469) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK1 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587500 (CHEMBL5094437) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587491 (CHEMBL5092147) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311267 (2-chloro-4-(3-(2-methylpyridin-4-yl)-1H-1,2,4-tria...) Show SMILES Cc1cc(ccn1)-c1nnc([nH]1)-c1ccnc(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human))	BDBM50587489 (CHEMBL5085080) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant PDHK2 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116514 BindingDB Entry DOI: 10.7270/Q20K2DGG
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50311281 (3,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine \| CHEM...) Show SMILES c1cncc(c1)-c1nnc([nH]1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Fuji Yakuhin Co., Ltd Curated by ChEMBL					Assay Description Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometer				Bioorg Med Chem Lett 19: 6225-9 (2009) Article DOI: 10.1016/j.bmcl.2009.08.091 BindingDB Entry DOI: 10.7270/Q2XS5VHW
Fuji Yakuhin Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

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