Found 140 hits with Last Name = 'jang' and Initial = 'th' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581458
(CHEMBL5092802)Show SMILES COc1cc(ccc1OCCN1CCOCC1)N(CC1CCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581397
(CHEMBL5085353)Show SMILES COc1cc(NC(=S)N(CCCn2cncc2C)C(C)C)ccc1OCCCCc1ccnc(N)c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581442
(CHEMBL5086776)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(CC1CCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581399
(CHEMBL5085226)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCCC1)C(=S)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581400
(CHEMBL5075575)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCCCC1)C(=S)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581426
(CHEMBL5089771)Show SMILES COc1cc(ccc1OCCCCN(C)C)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581398
(CHEMBL5083519)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCC1)C(=S)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581450
(CHEMBL5085670)Show SMILES COc1cc(ccc1OCCN1CCN(C)CC1)N(CC1CCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581412
(CHEMBL5088732)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(Cc1ccccc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581445
(CHEMBL5089285)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581441
(CHEMBL5081653)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50508111
(CHEMBL4520827)Show SMILES CCCCC1=NC(C)=C(CC(=S)N(C)C)CN1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4,7| Show InChI InChI=1S/C27H33N7S/c1-5-6-11-25-28-19(2)22(16-26(35)33(3)4)18-34(25)17-20-12-14-21(15-13-20)23-9-7-8-10-24(23)27-29-31-32-30-27/h7-10,12-15H,5-6,11,16-18H2,1-4H3,(H,29,30,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boryung Pharmaceuticals Co. Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay |
Bioorg Med Chem Lett 29: 631-637 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.043
BindingDB Entry DOI: 10.7270/Q22B929Z |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581436
(CHEMBL5081891)Show SMILES COc1cc(ccc1OCCc1ccnc(N)c1)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581443
(CHEMBL5083687)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581434
(CHEMBL5081537)Show SMILES COc1cc(ccc1OCCc1ccnc(N)c1)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581451
(CHEMBL5092925)Show SMILES COc1cc(ccc1OCCN1CCN(C)CC1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50508110
(CHEMBL4444760)Show SMILES CCCCC1=NC(C(C)C)=C(CC(=S)N2CCCC2)CN1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1 |t:4,9| Show InChI InChI=1S/C32H39N5O2S/c1-4-5-12-28-33-30(22(2)3)25(19-29(40)36-17-8-9-18-36)21-37(28)20-23-13-15-24(16-14-23)26-10-6-7-11-27(26)31-34-32(38)39-35-31/h6-7,10-11,13-16,22H,4-5,8-9,12,17-21H2,1-3H3,(H,34,35,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boryung Pharmaceuticals Co. Ltd.
Curated by ChEMBL
| Assay Description
Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay |
Bioorg Med Chem Lett 29: 631-637 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.043
BindingDB Entry DOI: 10.7270/Q22B929Z |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581460
(CHEMBL5084485)Show SMILES COc1cc(ccc1OCCN1CCOCC1)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581448
(CHEMBL5094369)Show SMILES COc1cc(ccc1OCCN1CCN(C)CC1)N(C(C)C)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581422
(CHEMBL5079181)Show SMILES COc1cc(ccc1OCCCN(C)C)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581410
(CHEMBL5081843)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581453
(CHEMBL5076836)Show SMILES COc1cc(ccc1OCCN1CCN(C)CC1)N(Cc1cccnc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581473
(CHEMBL5088100)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(Cc1ccc(F)cc1)C(=O)NCc1ccc2[nH]cnc2c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581409
(CHEMBL5088413)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(CC1CCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581452
(CHEMBL5092800)Show SMILES COc1cc(ccc1OCCN1CCN(C)CC1)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581408
(CHEMBL5088872)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581435
(CHEMBL5089539)Show SMILES COc1cc(ccc1OCCc1ccnc(N)c1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581446
(CHEMBL5092266)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(Cc1cccnc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581444
(CHEMBL5087075)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(C(=O)NCCCn1cncc1C)c1ccccc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581468
(CHEMBL5076908)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCCCC1)C(=O)NCc1ccc2[nH]cnc2c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581413
(CHEMBL5079213)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581461
(CHEMBL5079847)Show SMILES COc1cc(ccc1OCCN1CCOCC1)N(Cc1cccnc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50237457
(CHEMBL4097599)Show SMILES COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 Show InChI InChI=1S/C24H32N6O2S/c1-18-16-26-17-30(18)12-5-10-28-24(33)29-20-7-8-21(22(15-20)31-2)32-13-4-3-6-19-9-11-27-23(25)14-19/h7-9,11,14-17H,3-6,10,12-13H2,1-2H3,(H2,25,27)(H2,28,29,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581405
(CHEMBL5093267)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581439
(CHEMBL5082895)Show SMILES CCN(C(=O)NCCCn1cncc1C)c1ccc(OCCN2CCNCC2)c(OC)c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581406
(CHEMBL5078420)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581440
(CHEMBL5093456)Show SMILES COc1cc(ccc1OCCN1CCNCC1)N(C(C)C)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581479
(CHEMBL5069682)Show SMILES COc1ccc(cc1OC)N(C1CCN(C)CC1)C(=S)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581407
(CHEMBL5078932)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581404
(CHEMBL5072773)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C(C)C)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581415
(CHEMBL5079568)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)C1(CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Mus musculus (mouse)) | BDBM50581435
(CHEMBL5089539)Show SMILES COc1cc(ccc1OCCc1ccnc(N)c1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of mouse QPCT measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581429
(CHEMBL5082884)Show SMILES COc1cc(ccc1OCCCCN(C)C)N(Cc1ccc(F)cc1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581421
(CHEMBL5077722)Show SMILES COc1cc(ccc1OCCN(C)C)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581457
(CHEMBL5091269)Show SMILES COc1cc(ccc1OCCN1CCOCC1)N(C1CCCCC1)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581395
(CHEMBL5079317)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C)C(=S)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581466
(CHEMBL5083460)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCC1)C(=O)NCc1ccc2[nH]cnc2c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581402
(CHEMBL5094798)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C)C(=O)NCCCn1cncc1C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581411
(CHEMBL5093282)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C(=O)NCCCn1cncc1C)c1ccccc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Glutaminyl-peptide cyclotransferase
(Homo sapiens (Human)) | BDBM50581474
(CHEMBL5079535)Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(Cc1cccnc1)C(=O)NCc1ccc2[nH]cnc2c1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44 |
More data for this
Ligand-Target Pair | |
Search and Browse
