BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 516 hits with Last Name = 'park' and Initial = 'wj'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502377
PNG
(N-[4-(7- methoxy-1- methyl- [1,2,4]tri- azolo[4,3-...)
Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)C(C)C)c1nnc(C)n21
Show InChI InChI=1S/C19H26N6O2/c1-12(2)19(26)21-10-6-5-9-20-17-18-24-23-13(3)25(18)16-8-7-14(27-4)11-15(16)22-17/h7-8,11-12H,5-6,9-10H2,1-4H3,(H,20,22)(H,21,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502344
PNG
(2-methoxy-N- {4-[1-methyl- 7-(1-methyl- 1H-benzo- ...)
Show SMILES COc1ccccc1C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C
Show InChI InChI=1S/C30H30N8O2/c1-19-35-36-29-27(31-16-8-9-17-32-30(39)21-10-4-7-13-26(21)40-3)33-23-18-20(14-15-25(23)38(19)29)28-34-22-11-5-6-12-24(22)37(28)2/h4-7,10-15,18H,8-9,16-17H2,1-3H3,(H,31,33)(H,32,39)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.600n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502348
PNG
(3-methyl-N- {4-[1-methyl- 7-(1-propyl- 1H- benzoim...)
Show SMILES CCCn1c(nc2ccccc12)-c1ccc2c(c1)nc(NCCCCNC(=O)CC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C29H36N8O/c1-5-16-36-24-11-7-6-10-22(24)33-28(36)21-12-13-25-23(18-21)32-27(29-35-34-20(4)37(25)29)31-15-9-8-14-30-26(38)17-19(2)3/h6-7,10-13,18-19H,5,8-9,14-17H2,1-4H3,(H,30,38)(H,31,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.900n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502479
PNG
((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C27H41N7O5/c1-17(2)16-39-27(36)31-23(18(3)4)26(35)29-12-8-7-11-28-24-25-33-32-19(5)34(25)22-10-9-20(15-21(22)30-24)38-14-13-37-6/h9-10,15,17-18,23H,7-8,11-14,16H2,1-6H3,(H,28,30)(H,29,35)(H,31,36)/t23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502480
PNG
((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...)
Show SMILES CCCOC(=O)N[C@@H](C(C)C)C(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12 |r|
Show InChI InChI=1S/C26H39N7O5/c1-6-13-38-26(35)30-22(17(2)3)25(34)28-12-8-7-11-27-23-24-32-31-18(4)33(24)21-10-9-19(16-20(21)29-23)37-15-14-36-5/h9-10,16-17,22H,6-8,11-15H2,1-5H3,(H,27,29)(H,28,34)(H,30,35)/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502481
PNG
((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C26H39N7O5/c1-16(2)22(30-26(35)38-17(3)4)25(34)28-12-8-7-11-27-23-24-32-31-18(5)33(24)21-10-9-19(15-20(21)29-23)37-14-13-36-6/h9-10,15-17,22H,7-8,11-14H2,1-6H3,(H,27,29)(H,28,34)(H,30,35)/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502334
PNG
(N-{4-[7-(5,6- dimethoxy- 1H-benzo- imidazole-2- yl...)
Show SMILES CNc1cc2nc([nH]c2cc1OC)-c1ccc2c(c1)nc(NCCCCNC(=O)CC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C28H35N9O2/c1-16(2)12-25(38)30-10-6-7-11-31-27-28-36-35-17(3)37(28)23-9-8-18(13-21(23)34-27)26-32-19-14-22(29-4)24(39-5)15-20(19)33-26/h8-9,13-16,29H,6-7,10-12H2,1-5H3,(H,30,38)(H,31,34)(H,32,33)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9


(Homo sapiens (Human))		BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Department of Life Science and National Research Laboratory of Proteolysis

Curated by ChEMBL


Assay Description
In vitro inhibition of A disintegrin and metalloproteinase domain 9 (ADAM9)

Bioorg Med Chem Lett 14: 6071-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.082
BindingDB Entry DOI: 10.7270/Q29Z94DH
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502328
PNG
(US11028090, Example 222)
Show SMILES CC(C)CC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C
Show InChI InChI=1S/C27H32N8O/c1-17(2)15-24(36)28-13-7-8-14-29-25-27-33-32-18(3)35(27)23-12-11-19(16-21(23)30-25)26-31-20-9-5-6-10-22(20)34(26)4/h5-6,9-12,16-17H,7-8,13-15H2,1-4H3,(H,28,36)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502494
PNG
(2,3- dichloro-N- {4-[7-(2- methoxy- ethoxy)-1- met...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)c1cccc(Cl)c1Cl)c1nnc(C)n21
Show InChI InChI=1S/C24H26Cl2N6O3/c1-15-30-31-23-22(29-19-14-16(35-13-12-34-2)8-9-20(19)32(15)23)27-10-3-4-11-28-24(33)17-6-5-7-18(25)21(17)26/h5-9,14H,3-4,10-13H2,1-2H3,(H,27,29)(H,28,33)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502455
PNG
(US11028090, Example 372 | {4-[7-(2- methoxy- ethox...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Oc1ccccc1)c1nnc(C)n21
Show InChI InChI=1S/C24H28N6O4/c1-17-28-29-23-22(25-12-6-7-13-26-24(31)34-18-8-4-3-5-9-18)27-20-16-19(33-15-14-32-2)10-11-21(20)30(17)23/h3-5,8-11,16H,6-7,12-15H2,1-2H3,(H,25,27)(H,26,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502471
PNG
(2-(S)- hydroxy-N- {4-[7-(2- methoxy- ethoxy)-1- me...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](O)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C22H32N6O4/c1-14(2)19(29)22(30)24-10-6-5-9-23-20-21-27-26-15(3)28(21)18-8-7-16(13-17(18)25-20)32-12-11-31-4/h7-8,13-14,19,29H,5-6,9-12H2,1-4H3,(H,23,25)(H,24,30)/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502501
PNG
(N-{4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tri...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Cc1ccccc1)c1nnc(C)n21
Show InChI InChI=1S/C25H30N6O3/c1-18-29-30-25-24(27-13-7-6-12-26-23(32)16-19-8-4-3-5-9-19)28-21-17-20(34-15-14-33-2)10-11-22(21)31(18)25/h3-5,8-11,17H,6-7,12-16H2,1-2H3,(H,26,32)(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502343
PNG
(4-methyl- pentanoic acid-{4-[1- methyl-7- (1-meth...)
Show SMILES CC(C)CCC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C
Show InChI InChI=1S/C28H34N8O/c1-18(2)11-14-25(37)29-15-7-8-16-30-26-28-34-33-19(3)36(28)24-13-12-20(17-22(24)31-26)27-32-21-9-5-6-10-23(21)35(27)4/h5-6,9-10,12-13,17-18H,7-8,11,14-16H2,1-4H3,(H,29,37)(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502290
PNG
(US11028090, Example 176 | [4-(7,8- diethoxy-1- met...)
Show SMILES CCOc1cc2nc(NCCCCNC(=O)OCC(C)C)c3nnc(C)n3c2cc1OCC
Show InChI InChI=1S/C23H34N6O4/c1-6-31-19-12-17-18(13-20(19)32-7-2)29-16(5)27-28-22(29)21(26-17)24-10-8-9-11-25-23(30)33-14-15(3)4/h12-13,15H,6-11,14H2,1-5H3,(H,24,26)(H,25,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502340
PNG
(2,2-difluoro- N-{4-[1- methyl-7-(1- methyl-1H- ben...)
Show SMILES CCC(F)(F)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C
Show InChI InChI=1S/C26H28F2N8O/c1-4-26(27,28)25(37)30-14-8-7-13-29-22-24-34-33-16(2)36(24)21-12-11-17(15-19(21)31-22)23-32-18-9-5-6-10-20(18)35(23)3/h5-6,9-12,15H,4,7-8,13-14H2,1-3H3,(H,29,31)(H,30,37)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502217
PNG
(N-[4-(7,8- dimethoxy-1- methyl-[1,2,4] triazolo[4,...)
Show SMILES COc1cc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2cc1OC |r|
Show InChI InChI=1S/C21H30N6O4/c1-12(2)18(28)21(29)23-9-7-6-8-22-19-20-26-25-13(3)27(20)15-11-17(31-5)16(30-4)10-14(15)24-19/h10-12,18,28H,6-9H2,1-5H3,(H,22,24)(H,23,29)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502466
PNG
(4-methyl- pentanoic acid{4-[7- (2-methoxy- ethoxy)...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CCC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C23H34N6O3/c1-16(2)7-10-21(30)24-11-5-6-12-25-22-23-28-27-17(3)29(23)20-9-8-18(15-19(20)26-22)32-14-13-31-4/h8-9,15-16H,5-7,10-14H2,1-4H3,(H,24,30)(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502336
PNG
(US11028090, Example 229 | {4-[1-methyl- 7-(1-methy...)
Show SMILES Cc1nnc2c(NCCCCNC(=O)OC3CCCC3)nc3cc(ccc3n12)-c1nc2ccccc2n1C
Show InChI InChI=1S/C28H32N8O2/c1-18-33-34-27-25(29-15-7-8-16-30-28(37)38-20-9-3-4-10-20)31-22-17-19(13-14-24(22)36(18)27)26-32-21-11-5-6-12-23(21)35(26)2/h5-6,11-14,17,20H,3-4,7-10,15-16H2,1-2H3,(H,29,31)(H,30,37)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502502
PNG
(1-isopropyl-3- {4-[7-(2- methoxy- ethoxy)-1- methy...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)NC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C21H31N7O3/c1-14(2)24-21(29)23-10-6-5-9-22-19-20-27-26-15(3)28(20)18-8-7-16(13-17(18)25-19)31-12-11-30-4/h7-8,13-14H,5-6,9-12H2,1-4H3,(H,22,25)(H2,23,24,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502475
PNG
(3-cyclopentyl- N-{4-[7-(2- methoxy- ethoxy)-1- met...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CCC1CCCC1)c1nnc(C)n21
Show InChI InChI=1S/C25H36N6O3/c1-18-29-30-25-24(27-14-6-5-13-26-23(32)12-9-19-7-3-4-8-19)28-21-17-20(34-16-15-33-2)10-11-22(21)31(18)25/h10-11,17,19H,3-9,12-16H2,1-2H3,(H,26,32)(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502449
PNG
(US11028090, Example 366 | US11028090, Example 428 ...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)OC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C21H30N6O4/c1-14(2)31-21(28)23-10-6-5-9-22-19-20-26-25-15(3)27(20)18-8-7-16(13-17(18)24-19)30-12-11-29-4/h7-8,13-14H,5-6,9-12H2,1-4H3,(H,22,24)(H,23,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502252
PNG
(2-(S)-hydroxy-N- [4-(8-methoxy- 1-methyl-[1,2,4] t...)
Show SMILES COc1ccc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2c1 |r|
Show InChI InChI=1S/C20H28N6O3/c1-12(2)17(27)20(28)22-10-6-5-9-21-18-19-25-24-13(3)26(19)16-11-14(29-4)7-8-15(16)23-18/h7-8,11-12,17,27H,5-6,9-10H2,1-4H3,(H,21,23)(H,22,28)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502276
PNG
(US11028090, Example 161 | [4-(8- methoxy-1,6- dime...)
Show SMILES COc1cc(C)c2nc(NCCCCNC(=O)OC(C)C)c3nnc(C)n3c2c1
Show InChI InChI=1S/C20H28N6O3/c1-12(2)29-20(27)22-9-7-6-8-21-18-19-25-24-14(4)26(19)16-11-15(28-5)10-13(3)17(16)23-18/h10-12H,6-9H2,1-5H3,(H,21,23)(H,22,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502412
PNG
((S)-{1-[4- (7-methoxy- 1-methyl- [1,2,4]tri- azolo...)
Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C24H35N7O4/c1-14(2)20(28-24(33)35-15(3)4)23(32)26-12-8-7-11-25-21-22-30-29-16(5)31(22)19-10-9-17(34-6)13-18(19)27-21/h9-10,13-15,20H,7-8,11-12H2,1-6H3,(H,25,27)(H,26,32)(H,28,33)/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502331
PNG
(N-{4-[7-(1H- benzo- imidazole-2- yl)-1-methyl- [1,...)
Show SMILES CC(C)[C@@H](O)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2[nH]1 |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502392
PNG
(2-(R)- hydroxy-N- [4-(7- methoxy-1- methyl- [1,2,4...)
Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)[C@H](O)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C20H28N6O3/c1-12(2)17(27)20(28)22-10-6-5-9-21-18-19-25-24-13(3)26(19)16-8-7-14(29-4)11-15(16)23-18/h7-8,11-12,17,27H,5-6,9-10H2,1-4H3,(H,21,23)(H,22,28)/t17-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502288
PNG
(US11028090, Example 173 | [4-(7,8- diethoxy-1- met...)
Show SMILES CCOc1cc2nc(NCCCCNC(=O)OC(C)(C)C)c3nnc(C)n3c2cc1OCC
Show InChI InChI=1S/C23H34N6O4/c1-7-31-18-13-16-17(14-19(18)32-8-2)29-15(3)27-28-21(29)20(26-16)24-11-9-10-12-25-22(30)33-23(4,5)6/h13-14H,7-12H2,1-6H3,(H,24,26)(H,25,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502637
PNG
(US11028090, Example 579)
Show SMILES Cc1noc(C)c1-c1ccc2nc(NCCCCN)c3nnc(C)n3c2c1
Show InChI InChI=1S/C19H23N7O/c1-11-17(12(2)27-25-11)14-6-7-15-16(10-14)26-13(3)23-24-19(26)18(22-15)21-9-5-4-8-20/h6-7,10H,4-5,8-9,20H2,1-3H3,(H,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502640
PNG
(US11028090, Example 583)
Show SMILES Cc1noc(C)c1-c1ccc2c(c1)nc(NCCCCNC(=O)OC(C)(C)C)c1nnc(C)n21
Show InChI InChI=1S/C24H31N7O3/c1-14-20(15(2)34-30-14)17-9-10-19-18(13-17)27-21(22-29-28-16(3)31(19)22)25-11-7-8-12-26-23(32)33-24(4,5)6/h9-10,13H,7-8,11-12H2,1-6H3,(H,25,27)(H,26,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502641
PNG
(N-{4-[7- (3,5- dimethyl- isoxazol-4- yl)-1- methyl...)
Show SMILES CC(C)CC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1c(C)noc1C
Show InChI InChI=1S/C24H31N7O2/c1-14(2)12-21(32)25-10-6-7-11-26-23-24-29-28-17(5)31(24)20-9-8-18(13-19(20)27-23)22-15(3)30-33-16(22)4/h8-9,13-14H,6-7,10-12H2,1-5H3,(H,25,32)(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502450
PNG
(US11028090, Example 367 | US11028090, Example 368 ...)
Show SMILES CCCOC(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12
Show InChI InChI=1S/C21H30N6O4/c1-4-11-31-21(28)23-10-6-5-9-22-19-20-26-25-15(2)27(20)18-8-7-16(14-17(18)24-19)30-13-12-29-3/h7-8,14H,4-6,9-13H2,1-3H3,(H,22,24)(H,23,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502465
PNG
(N-{4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tri...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CC(C)(C)C)c1nnc(C)n21
Show InChI InChI=1S/C23H34N6O3/c1-16-27-28-22-21(25-11-7-6-10-24-20(30)15-23(2,3)4)26-18-14-17(32-13-12-31-5)8-9-19(18)29(16)22/h8-9,14H,6-7,10-13,15H2,1-5H3,(H,24,30)(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502473
PNG
(2,2- difluoro-N- {4-[7-(2- methoxy- ethoxy)-1- met...)
Show SMILES CCC(F)(F)C(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12
Show InChI InChI=1S/C21H28F2N6O3/c1-4-21(22,23)20(30)25-10-6-5-9-24-18-19-28-27-14(2)29(19)17-8-7-15(13-16(17)26-18)32-12-11-31-3/h7-8,13H,4-6,9-12H2,1-3H3,(H,24,26)(H,25,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502213
PNG
(4-methyl- pentanoic acid [4-(7,8- dimethoxy-1- met...)
Show SMILES COc1cc2nc(NCCCCNC(=O)CCC(C)C)c3nnc(C)n3c2cc1OC
Show InChI InChI=1S/C22H32N6O3/c1-14(2)8-9-20(29)23-10-6-7-11-24-21-22-27-26-15(3)28(22)17-13-19(31-5)18(30-4)12-16(17)25-21/h12-14H,6-11H2,1-5H3,(H,23,29)(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502557
PNG
(2-(S)- hydroxy-N- [4-(7- methoxy-1- methyl-8- trif...)
Show SMILES COc1cc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2cc1C(F)(F)F |r|
Show InChI InChI=1S/C21H27F3N6O3/c1-11(2)17(31)20(32)26-8-6-5-7-25-18-19-29-28-12(3)30(19)15-9-13(21(22,23)24)16(33-4)10-14(15)27-18/h9-11,17,31H,5-8H2,1-4H3,(H,25,27)(H,26,32)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502566
PNG
(4-(7- imidazole- 1-yl-1- methyl- [1,2,4]triazolo[4...)
Show SMILES CC(C)COC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-n1ccnc1
Show InChI InChI=1S/C22H28N8O2/c1-15(2)13-32-22(31)25-9-5-4-8-24-20-21-28-27-16(3)30(21)19-7-6-17(12-18(19)26-20)29-11-10-23-14-29/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H,24,26)(H,25,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502527
PNG
(US11028090, Example 448)
Show SMILES CC(C)Oc1ccc2c(c1)nc(NCCCCN)c1nnc(C)n21
Show InChI InChI=1S/C17H24N6O/c1-11(2)24-13-6-7-15-14(10-13)20-16(19-9-5-4-8-18)17-22-21-12(3)23(15)17/h6-7,10-11H,4-5,8-9,18H2,1-3H3,(H,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502656
PNG
(US11028090, Example 622 | US11028090, Example 623 ...)
Show SMILES CCc1nnc2c(NCCCCNC(=O)OC(C)C)nc3cc(OC)ccc3n12
Show InChI InChI=1S/C20H28N6O3/c1-5-17-24-25-19-18(21-10-6-7-11-22-20(27)29-13(2)3)23-15-12-14(28-4)8-9-16(15)26(17)19/h8-9,12-13H,5-7,10-11H2,1-4H3,(H,21,23)(H,22,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502157
PNG
(2-(S)- hydroxy-N- [4-(1- methyl- [1,2,4] triazolo ...)
Show SMILES CC(C)[C@H](O)C(=O)NCCCCNc1nc2ccccc2n2c(C)nnc12 |r|
Show InChI InChI=1S/C19H26N6O2/c1-12(2)16(26)19(27)21-11-7-6-10-20-17-18-24-23-13(3)25(18)15-9-5-4-8-14(15)22-17/h4-5,8-9,12,16,26H,6-7,10-11H2,1-3H3,(H,20,22)(H,21,27)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 12


(Homo sapiens (Human))		BDBM50062351
PNG
((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Show SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |r|
Show InChI InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 5.93n/an/an/an/an/an/a



Department of Life Science and National Research Laboratory of Proteolysis

Curated by ChEMBL


Assay Description
Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay

Bioorg Med Chem Lett 14: 6071-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.082
BindingDB Entry DOI: 10.7270/Q29Z94DH
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502470
PNG
(2-(R)- hydroxy-N- {4-[7-(2- methoxy- ethoxy)-1- me...)
Show SMILES CC[C@@H](O)C(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12 |r|
Show InChI InChI=1S/C21H30N6O4/c1-4-18(28)21(29)23-10-6-5-9-22-19-20-26-25-14(2)27(20)17-8-7-15(13-16(17)24-19)31-12-11-30-3/h7-8,13,18,28H,4-6,9-12H2,1-3H3,(H,22,24)(H,23,29)/t18-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502341
PNG
(2-(S)- hydroxy-3- methyl-N-{4- [1-methyl-7- (1-met...)
Show SMILES CC(C)[C@H](O)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C |r|
Show InChI InChI=1S/C27H32N8O2/c1-16(2)23(36)27(37)29-14-8-7-13-28-24-26-33-32-17(3)35(26)22-12-11-18(15-20(22)30-24)25-31-19-9-5-6-10-21(19)34(25)4/h5-6,9-12,15-16,23,36H,7-8,13-14H2,1-4H3,(H,28,30)(H,29,37)/t23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502261
PNG
(2-(S)- hydroxy-N- [4-(6- methoxy- 1,7- dimethyl- [...)
Show SMILES COc1c(C)ccc2c1nc(NCCCCNC(=O)[C@@H](O)C(C)C)c1nnc(C)n21 |r|
Show InChI InChI=1S/C21H30N6O3/c1-12(2)17(28)21(29)23-11-7-6-10-22-19-20-26-25-14(4)27(20)15-9-8-13(3)18(30-5)16(15)24-19/h8-9,12,17,28H,6-7,10-11H2,1-5H3,(H,22,24)(H,23,29)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502179
PNG
(US11028090, Example 39)
Show SMILES CC(C)[C@H](O)C(=O)NCCCCNc1nc2cc(F)c(F)cc2n2c(C)nnc12
Show InChI InChI=1S/C19H24F2N6O2/c1-10(2)16(28)19(29)23-7-5-4-6-22-17-18-26-25-11(3)27(18)15-9-13(21)12(20)8-14(15)24-17/h8-10,16,28H,4-7H2,1-3H3,(H,22,24)(H,23,29)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502623
PNG
(N-[4-(7- methoxy-1- methyl-8- propylamino- [1,2,4]...)
Show SMILES CCCNc1cc2c(cc1OC)nc(NCCCCNC(=O)CC(C)C)c1nnc(C)n21
Show InChI InChI=1S/C23H35N7O2/c1-6-9-24-18-13-19-17(14-20(18)32-5)27-22(23-29-28-16(4)30(19)23)26-11-8-7-10-25-21(31)12-15(2)3/h13-15,24H,6-12H2,1-5H3,(H,25,31)(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502643
PNG
(N-{4-[7- (3,5- dimethyl- isoxazol-4- yl)-1- methyl...)
Show SMILES CC(C)[C@H](O)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1c(C)noc1C |r|
Show InChI InChI=1S/C24H31N7O3/c1-13(2)21(32)24(33)26-11-7-6-10-25-22-23-29-28-16(5)31(23)19-9-8-17(12-18(19)27-22)20-14(3)30-34-15(20)4/h8-9,12-13,21,32H,6-7,10-11H2,1-5H3,(H,25,27)(H,26,33)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502445
PNG
(US11028090, Example 358)
Show SMILES CSc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](O)C(C)C)c1nnc(C)n21
Show InChI InChI=1S/C20H28N6O2S/c1-12(2)17(27)20(28)22-10-6-5-9-21-18-19-25-24-13(3)26(19)16-8-7-14(29-4)11-15(16)23-18/h7-8,11-12,17,27H,5-6,9-10H2,1-4H3,(H,21,23)(H,22,28)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502454
PNG
(US11028090, Example 371 | {4-[7-(2- methoxy- ethox...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)OC1CCCC1)c1nnc(C)n21
Show InChI InChI=1S/C23H32N6O4/c1-16-27-28-22-21(24-11-5-6-12-25-23(30)33-17-7-3-4-8-17)26-19-15-18(32-14-13-31-2)9-10-20(19)29(16)22/h9-10,15,17H,3-8,11-14H2,1-2H3,(H,24,26)(H,25,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM502477
PNG
((1-{4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tr...)
Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)C(NC(=O)OC(C)(C)C)C(C)C)c1nnc(C)n21
Show InChI InChI=1S/C27H41N7O5/c1-17(2)22(31-26(36)39-27(4,5)6)25(35)29-13-9-8-12-28-23-24-33-32-18(3)34(24)21-11-10-19(16-20(21)30-23)38-15-14-37-7/h10-11,16-17,22H,8-9,12-15H2,1-7H3,(H,28,30)(H,29,35)(H,31,36)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology

US Patent


Assay Description
The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...

US Patent US11028090 (2021)


BindingDB Entry DOI: 10.7270/Q22J6G0T
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 516 total )  |  Next  |  Last  >>
Jump to: