Compile Data Set for Download or QSAR

Found 84 hits with Last Name = 'amemiya' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50001922 (2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...) Show SMILES C(C1=NCCN1)c1cccc2ccccc12 |t:1| Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	0.00110	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230389 (CHEMBL541105) Show SMILES Cl.CC(c1c[nH]cn1)c1cccc2ccccc12 Show InChI InChI=1S/C15H14N2.ClH/c1-11(15-9-16-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-11H,1H3,(H,16,17);1H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.00340	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was tested for Adrenergic activity against Alpha-2 adrenergic receptor from rat aorta				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230393 (CHEMBL553231) Show SMILES Cl.CC(C1=NCCN1)c1cccc2ccccc12 |t:2| Show InChI InChI=1S/C15H16N2.ClH/c1-11(15-16-9-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-8,11H,9-10H2,1H3,(H,16,17);1H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0140	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230395 (CHEMBL557985) Show SMILES Cl.CC(C1=NCCN1)c1ccc2ccccc2c1 |t:2| Show InChI InChI=1S/C15H16N2.ClH/c1-11(15-16-8-9-17-15)13-7-6-12-4-2-3-5-14(12)10-13;/h2-7,10-11H,8-9H2,1H3,(H,16,17);1H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.0160	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230388 (CHEMBL537830) Show SMILES Cl.C(c1ncc[nH]1)c1cccc2ccccc12 Show InChI InChI=1S/C14H12N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-9H,10H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0340	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230394 (CHEMBL538801) Show SMILES Cl.CC(c1c[nH]cn1)c1ccc2ccccc2c1 Show InChI InChI=1S/C15H14N2.ClH/c1-11(15-9-16-10-17-15)13-7-6-12-4-2-3-5-14(12)8-13;/h2-11H,1H3,(H,16,17);1H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230392 (CHEMBL554581) Show SMILES Cl.CC(c1ncc[nH]1)c1cccc2ccccc12 Show InChI InChI=1S/C15H14N2.ClH/c1-11(15-16-9-10-17-15)13-8-4-6-12-5-2-3-7-14(12)13;/h2-11H,1H3,(H,16,17);1H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50230391 (CHEMBL164540) Show SMILES OC(=O)C(O)=O.CC(c1ncc[nH]1)c1ccc2ccccc2c1 Show InChI InChI=1S/C15H14N2.C2H2O4/c1-11(15-16-8-9-17-15)13-7-6-12-4-2-3-5-14(12)10-13;3-1(4)2(5)6/h2-11H,1H3,(H,16,17);(H,3,4)(H,5,6)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Compound was evaluated for Adrenergic activity against Alpha-2 adrenergic receptor in human platelets				J Med Chem 35: 750-5 (1992) BindingDB Entry DOI: 10.7270/Q27H1MTJ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049128 (5-(1-Hydroxy-ethyl)-2-propyl-3-[2'-(2H-tetrazol-5-...) Show SMILES CCCc1nc(C(C)O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H24N6O3/c1-3-6-19-24-20(14(2)30)21(23(31)32)29(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)22-25-27-28-26-22/h4-5,7-12,14,30H,3,6,13H2,1-2H3,(H,31,32)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049118 (2-Ethyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...) Show SMILES CCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O Show InChI InChI=1S/C23H24N6O3/c1-4-18-24-20(23(2,3)32)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-7-5-6-8-17(16)21-25-27-28-26-21/h5-12,32H,4,13H2,1-3H3,(H,30,31)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 |t:3| Show InChI InChI=1S/C13H12N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-6,8H,1-2,7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049123 (5-Hydroxymethyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-...) Show SMILES CCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H22N6O3/c1-2-5-19-23-18(13-29)20(22(30)31)28(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21-24-26-27-25-21/h3-4,6-11,29H,2,5,12-13H2,1H3,(H,30,31)(H,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50241364 (4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-te...) Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O Show InChI InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair				3D Structure (crystal)
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049107 (2-Propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...) Show SMILES CCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C21H20N6O2/c1-2-5-19-22-12-18(21(28)29)27(19)13-14-8-10-15(11-9-14)16-6-3-4-7-17(16)20-23-25-26-24-20/h3-4,6-12H,2,5,13H2,1H3,(H,28,29)(H,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049109 (2-Butyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...) Show SMILES CCCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O Show InChI InChI=1S/C25H28N6O3/c1-4-5-10-20-26-22(25(2,3)34)21(24(32)33)31(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)23-27-29-30-28-23/h6-9,11-14,34H,4-5,10,15H2,1-3H3,(H,32,33)(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049124 (5-Methyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bipheny...) Show SMILES CCCc1nc(C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H22N6O2/c1-3-6-19-23-14(2)20(22(29)30)28(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21-24-26-27-25-21/h4-5,7-12H,3,6,13H2,1-2H3,(H,29,30)(H,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049116 (5-Ethyl-2-propyl-3-(2'-tetrazol-1-yl-biphenyl-4-yl...) Show SMILES CCCc1nc(CC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C23H24N6O2/c1-3-7-20-24-19(4-2)21(23(30)31)29(20)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-25-27-28-26-22/h5-6,8-13H,3-4,7,14H2,1-2H3,(H,30,31)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 |t:3| Show InChI InChI=1S/C13H12N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-6,8H,1-2,7H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A2 synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018179 (2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1 |t:3| Show InChI InChI=1S/C13H12N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-6,8H,1-2,7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI InChI=1S/C13H14N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-5,8,10H,1-2,6-7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in humans				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50006909 (2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50006909 (2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI InChI=1S/C13H14N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-5,8,10H,1-2,6-7H2,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018181 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2cc(Cn3ccnc3)sc2C1 Show InChI InChI=1S/C13H14N2O2S/c16-13(17)10-2-1-9-5-11(18-12(9)6-10)7-15-4-3-14-8-15/h3-5,8,10H,1-2,6-7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A synthetase in humans				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049112 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-et...) Show SMILES CCCc1nc(C(C)O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H24N2O5/c1-3-6-19-24-20(14(2)26)21(23(29)30)25(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)22(27)28/h4-5,7-12,14,26H,3,6,13H2,1-2H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049132 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-1-...) Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(C)(C)O Show InChI InChI=1S/C24H26N2O5/c1-4-7-19-25-21(24(2,3)31)20(23(29)30)26(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22(27)28/h5-6,8-13,31H,4,7,14H2,1-3H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049122 (2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-(1-hy...) Show SMILES CCCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(C)(C)O Show InChI InChI=1S/C25H28N2O5/c1-4-5-10-20-26-22(25(2,3)32)21(24(30)31)27(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)23(28)29/h6-9,11-14,32H,4-5,10,15H2,1-3H3,(H,28,29)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049117 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-ethyl-5-(1-hy...) Show SMILES CCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(C)(C)O Show InChI InChI=1S/C23H24N2O5/c1-4-18-24-20(23(2,3)30)19(22(28)29)25(18)13-14-9-11-15(12-10-14)16-7-5-6-8-17(16)21(26)27/h5-12,30H,4,13H2,1-3H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049130 (5-Isopropyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCCc1nc(C(C)C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H26N6O2/c1-4-7-20-25-21(15(2)3)22(24(31)32)30(20)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)23-26-28-29-27-23/h5-6,8-13,15H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049113 (5-Isopropenyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-bi...) Show SMILES CCCc1nc(C(C)=C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H24N6O2/c1-4-7-20-25-21(15(2)3)22(24(31)32)30(20)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)23-26-28-29-27-23/h5-6,8-13H,2,4,7,14H2,1,3H3,(H,31,32)(H,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049106 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-hydroxy-1-...) Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(C)(O)CC Show InChI InChI=1S/C25H28N2O5/c1-4-8-20-26-22(25(3,32)5-2)21(24(30)31)27(20)15-16-11-13-17(14-12-16)18-9-6-7-10-19(18)23(28)29/h6-7,9-14,32H,4-5,8,15H2,1-3H3,(H,28,29)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049108 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...) Show SMILES CCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H22N2O5/c1-2-5-19-23-18(13-25)20(22(28)29)24(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21(26)27/h3-4,6-11,25H,2,5,12-13H2,1H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049108 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-hydroxymethyl...) Show SMILES CCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H22N2O5/c1-2-5-19-23-18(13-25)20(22(28)29)24(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21(26)27/h3-4,6-11,25H,2,5,12-13H2,1H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049126 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-3H-imi...) Show SMILES CCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C21H20N2O4/c1-2-5-19-22-12-18(21(26)27)23(19)13-14-8-10-15(11-9-14)16-6-3-4-7-17(16)20(24)25/h3-4,6-12H,2,5,13H2,1H3,(H,24,25)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50282291 (2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-hydro...) Show SMILES CCCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H24N2O5/c1-2-3-8-20-24-19(14-26)21(23(29)30)25(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(27)28/h4-7,9-12,26H,2-3,8,13-14H2,1H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018183 (2-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)C1CCc2sc(Cn3ccnc3)cc2C1 Show InChI InChI=1S/C13H14N2O2S/c16-13(17)9-1-2-12-10(5-9)6-11(18-12)7-15-4-3-14-8-15/h3-4,6,8-9H,1-2,5,7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018186 (2-Imidazol-1-ylmethyl-6,7-dihydro-benzo[b]thiophen...) Show SMILES OC(=O)C1=Cc2cc(Cn3ccnc3)sc2CC1 |t:3| Show InChI InChI=1S/C13H12N2O2S/c16-13(17)9-1-2-12-10(5-9)6-11(18-12)7-15-4-3-14-8-15/h3-6,8H,1-2,7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049110 (2-Propyl-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...) Show SMILES CCCc1nc(C(O)=O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C22H20N6O4/c1-2-5-17-23-18(21(29)30)19(22(31)32)28(17)12-13-8-10-14(11-9-13)15-6-3-4-7-16(15)20-24-26-27-25-20/h3-4,6-11H,2,5,12H2,1H3,(H,29,30)(H,31,32)(H,24,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049103 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-ethyl-2-propy...) Show SMILES CCCc1nc(CC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C23H24N2O4/c1-3-7-20-24-19(4-2)21(23(28)29)25(20)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22(26)27/h5-6,8-13H,3-4,7,14H2,1-2H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018178 (2-(2-Imidazol-1-yl-ethyl)-6,7-dihydro-benzo[b]thio...) Show SMILES OC(=O)C1=Cc2cc(CCn3ccnc3)sc2CC1 |t:3| Show InChI InChI=1S/C14H14N2O2S/c17-14(18)10-1-2-13-11(7-10)8-12(19-13)3-5-16-6-4-15-9-16/h4,6-9H,1-3,5H2,(H,17,18)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-1-3-11(4-2-10)17-8-7-14-6-5-13-9-14/h1-6,9H,7-8H2,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM7962 (4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...) Show SMILES OC(=O)c1ccc(OCCn2ccnc2)cc1 Show InChI InChI=1S/C12H12N2O3/c15-12(16)10-1-3-11(4-2-10)17-8-7-14-6-5-13-9-14/h1-6,9H,7-8H2,(H,15,16)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of platelet microsomal thromboxane A2 synthetase in rabbits				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049129 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-(1-ethyl-1-hy...) Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(O)(CC)CC Show InChI InChI=1S/C26H30N2O5/c1-4-9-21-27-23(26(33,5-2)6-3)22(25(31)32)28(21)16-17-12-14-18(15-13-17)19-10-7-8-11-20(19)24(29)30/h7-8,10-15,33H,4-6,9,16H2,1-3H3,(H,29,30)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049104 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-methyl-2-prop...) Show SMILES CCCc1nc(C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H22N2O4/c1-3-6-19-23-14(2)20(22(27)28)24(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21(25)26/h4-5,7-12H,3,6,13H2,1-2H3,(H,25,26)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018176 (2-(Imidazol-1-yl-phenyl-methyl)-6,7-dihydro-benzo[...) Show SMILES OC(=O)C1=Cc2cc(sc2CC1)C(c1ccccc1)n1ccnc1 |t:3| Show InChI InChI=1S/C19H16N2O2S/c22-19(23)14-6-7-16-15(10-14)11-17(24-16)18(21-9-8-20-12-21)13-4-2-1-3-5-13/h1-5,8-12,18H,6-7H2,(H,22,23)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50018184 (5-Imidazol-1-ylmethyl-4,5,6,7-tetrahydro-benzo[b]t...) Show SMILES OC(=O)c1cc2CC(Cn3ccnc3)CCc2s1 Show InChI InChI=1S/C13H14N2O2S/c16-13(17)12-6-10-5-9(1-2-11(10)18-12)7-15-4-3-14-8-15/h3-4,6,8-9H,1-2,5,7H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase				J Med Chem 32: 1265-72 (1989) BindingDB Entry DOI: 10.7270/Q2FF3RBV
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50009714 (CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50009714 (CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50009505 (2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chlor...) Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H21ClN2O4/c1-2-3-8-18-24-20(23)19(22(28)29)25(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21(26)27/h4-7,9-12H,2-3,8,13H2,1H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50009505 (2-Butyl-3-(2'-carboxy-biphenyl-4-ylmethyl)-5-chlor...) Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H21ClN2O4/c1-2-3-8-18-24-20(23)19(22(28)29)25(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21(26)27/h4-7,9-12H,2-3,8,13H2,1H3,(H,26,27)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair

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