Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM284944 (US10023583, Example 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10023583 (2018) BindingDB Entry DOI: 10.7270/Q29Z96X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM401319 (US10005762, Example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271290 (US10059720, Example 105 | US10975091, Example 105) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271290 (US10059720, Example 105 | US10975091, Example 105) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM401367 (US10005762, Example 47) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271330 (US10059720, Example 145 | US10975091, Example 145) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271330 (US10059720, Example 145 | US10975091, Example 145) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM284942 (US10023583, Example 14) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10023583 (2018) BindingDB Entry DOI: 10.7270/Q29Z96X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271310 (US10059720, Example 125 | US10975091, Example 125) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271310 (US10059720, Example 125 | US10975091, Example 125) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271316 (US10059720, Example 131 | US10975091, Example 131) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271316 (US10059720, Example 131 | US10975091, Example 131) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271309 (US10059720, Example 124 | US10975091, Example 124) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271309 (US10059720, Example 124 | US10975091, Example 124) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM401355 (US10005762, Example 35) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271318 (US10059720, Example 133 | US10975091, Example 133) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271288 (US10059720, Example 103 | US10975091, Example 103) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271198 (US10059720, Example 13 | US10975091, Example 13) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271288 (US10059720, Example 103 | US10975091, Example 103) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271198 (US10059720, Example 13 | US10975091, Example 13) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271318 (US10059720, Example 133 | US10975091, Example 133) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271258 (US10059720, Example 73 | US10975091, Example 73) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271258 (US10059720, Example 73 | US10975091, Example 73) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM284929 (US10023583, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10023583 (2018) BindingDB Entry DOI: 10.7270/Q29Z96X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271260 (US10059720, Example 75 | US10975091, Example 75) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271190 (US10059720, Example 6 | US10975091, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271213 (US10059720, Example 28 | US10975091, Example 28) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271260 (US10059720, Example 75 | US10975091, Example 75) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM401322 (US10005762, Example 4(3)) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271213 (US10059720, Example 28 | US10975091, Example 28) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271190 (US10059720, Example 6 | US10975091, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271330 (US10059720, Example 145 | US10975091, Example 145) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Rattus norvegicus) | BDBM271243 (US10059720, Example 58 | US10975091, Example 58) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP.... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271272 (US10059720, Example 87 | US10975091, Example 87) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair |
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