Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicase polyprotein 1ab (2019-nCoV) | BDBM581953 (WO2023004291, Compound CDD-1819) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | MCE PC cid PC sid UniChem | WIPO WO2023004291 | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581952 (WO2023004291, Compound CDD-1830) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581948 (WO2023004291, Compound CDD-1733) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | MCE PC cid PC sid UniChem | WIPO WO2023004291 | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581950 (WO2023004291, Compound CDD-1780) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab-His6 (2019-nCoV) | BDBM581944 (WO2023004291, Compound CDD-1714) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581944 (WO2023004291, Compound CDD-1714) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581951 (WO2023004291, Compound CDD-1795) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab-His6 (2019-nCoV) | BDBM484197 (CDD-1976 | WO2023004291, Compound CDD-1976) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484197 (CDD-1976 | WO2023004291, Compound CDD-1976) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab-His6 (2019-nCoV) | BDBM484196 (CDD-1713 | WO2023004291, Compound CDD-1713) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | WIPO WO2023004291 | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581949 (WO2023004291, Compound CDD-1829) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484196 (CDD-1713 | WO2023004291, Compound CDD-1713) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | WIPO WO2023004291 | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab-His6 (2019-nCoV) | BDBM581945 (WO2023004291, Compound CDD-1886) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM581945 (WO2023004291, Compound CDD-1886) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2023004291 | 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To evaluate the potency of synthesized compounds against Mpro, the proteolytic activity of 50 nM Mpro -His and Mpro was first measured in the presenc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7MGQ | |||||||||||
More data for this Ligand-Target Pair |